3ULI
| Human Cyclin Dependent Kinase 2 (CDK2) bound to azabenzimidazole derivative | 分子名称: | 1-(aminomethyl)-N-(3-{[6-bromo-2-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-7-yl]amino}propyl)cyclopropanecarboxamide, Cyclin-dependent kinase 2 | 著者 | Larsen, N.A, Tucker, J.A, Wang, T. | 登録日 | 2011-11-10 | 公開日 | 2013-08-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of azabenzimidazole derivatives as potent, selective inhibitors of TBK1/IKK epsilon kinases. Bioorg.Med.Chem.Lett., 22, 2012
|
|
3UEK
| Crystal structure of the catalytic domain of rat poly (ADP-ribose) glycohydrolase | 分子名称: | Poly(ADP-ribose) glycohydrolase | 著者 | Kim, I.K, Kiefer, J.R, Stegemann, R.A, Classen, S, Tainer, J.A, Ellenberger, T. | 登録日 | 2011-10-30 | 公開日 | 2012-05-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element. Nat.Struct.Mol.Biol., 19, 2012
|
|
3UGV
| Crystal structure of an enolase from alpha pretobacterium bal199 (EFI TARGET EFI-501650) with bound MG | 分子名称: | CHLORIDE ION, Enolase, MAGNESIUM ION, ... | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Wasserman, S.R, Morisco, L.L, Hillerich, B, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2011-11-03 | 公開日 | 2011-11-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of an enolase from alpha pretobacterium bal199 (EFI TARGET EFI-501650) with bound MG to be published
|
|
3USQ
| Structure of D159S/Y194F glycogenin mutant truncated at residue 270 | 分子名称: | CHLORIDE ION, GLYCEROL, Glycogenin-1 | 著者 | Issoglio, F.M, Carrizo, M.E, Romero, J.M, Curtino, J.A. | 登録日 | 2011-11-23 | 公開日 | 2011-12-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Mechanisms of monomeric and dimeric glycogenin autoglucosylation. J.Biol.Chem., 287, 2012
|
|
3UGE
| Silver Metallated Pseudomonas aeruginosa Azurin at 1.70 A | 分子名称: | Azurin, SILVER ION | 著者 | Panzner, M.J, Billinovich, S.M, Parker, J.A, Bladholm, E, Berry, S.M, Ziegler, C.J, Leeper, T.C. | 登録日 | 2011-11-02 | 公開日 | 2012-11-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Silver Metallation of Pseudomonas aeruginosa Azurin To be Published
|
|
3UEL
| Crystal structure of the catalytic domain of rat poly (ADP-ribose) glycohydrolase bound to ADP-HPD | 分子名称: | 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, Poly(ADP-ribose) glycohydrolase | 著者 | Kim, I.K, Kiefer, J.R, Stegemann, R.A, Classen, S, Tainer, J.A, Ellenberger, T. | 登録日 | 2011-10-30 | 公開日 | 2012-05-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element. Nat.Struct.Mol.Biol., 19, 2012
|
|
3UIY
| |
3S8E
| |
3UPI
| Synthesis of novel 4,5-dihydrofurano indoles and their evaluation as HCV NS5B polymerase inhibitors | 分子名称: | (3S)-6-(2,5-difluorobenzyl)-3-methyl-N-(methylsulfonyl)-8-(2-oxo-1,2-dihydropyridin-3-yl)-3,6-dihydro-2H-furo[2,3-e]indole-7-carboxamide, PHOSPHATE ION, RNA-directed RNA polymerase | 著者 | Velazquez, F, Venkataraman, S, Lesburg, C.A, Duca, J.S, Rosenblum, S.B, Kozlowski, J.A, Njoroge, F.G. | 登録日 | 2011-11-18 | 公開日 | 2012-01-25 | 最終更新日 | 2012-02-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Synthesis of New 4,5-Dihydrofuranoindoles and Their Evaluation as HCV NS5B Polymerase Inhibitors. Org.Lett., 14, 2012
|
|
3UMV
| Eukaryotic Class II CPD photolyase structure reveals a basis for improved UV-tolerance in plants | 分子名称: | 1,2-ETHANEDIOL, Deoxyribodipyrimidine photo-lyase, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Arvai, A.S, Hitomi, K, Getzoff, E.D, Tainer, J.A. | 登録日 | 2011-11-14 | 公開日 | 2011-12-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.705 Å) | 主引用文献 | Eukaryotic Class II Cyclobutane Pyrimidine Dimer Photolyase Structure Reveals Basis for Improved Ultraviolet Tolerance in Plants. J.Biol.Chem., 287, 2012
|
|
3UOT
| Crystal Structure of MDC1 FHA Domain in Complex with a Phosphorylated Peptide from the MDC1 N-terminus | 分子名称: | Mediator of DNA damage checkpoint protein 1 | 著者 | Clapperton, J.A, Lloyd, J, Haire, L.F, Li, J, Smerdon, S.J. | 登録日 | 2011-11-17 | 公開日 | 2011-12-28 | 最終更新日 | 2012-07-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator. Nucleic Acids Res., 40, 2012
|
|
3V5C
| Crystal structure of the mutant E234A of Galacturonate Dehydratase from GEOBACILLUS SP. complexed with Mg | 分子名称: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, Mandelate racemase/muconate lactonizing protein | 著者 | Fedorov, A.A, Fedorov, E.V, Groninger-Poe, F, Gerlt, J.A, Almo, S.C. | 登録日 | 2011-12-16 | 公開日 | 2012-12-19 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Crystal structure of the mutant E234A of Galacturonate Dehydratase from GEOBACILLUS SP. complexed with Mg To be Published
|
|
3UPH
| Synthesis of novel 4,5-dihydrofurano indoles and their evaluation as HCV NS5B polymerase inhibitors | 分子名称: | 6-(2,5-difluorobenzyl)-N-(methylsulfonyl)-8-(2-oxo-1,2-dihydropyridin-3-yl)-3,6-dihydro-2H-furo[2,3-e]indole-7-carboxamide, PHOSPHATE ION, RNA-directed RNA polymerase | 著者 | Velazquez, F, Venkataraman, S, Lesburg, C.A, Duca, J.S, Rosenblum, S.B, Kozlowski, J.A, Njoroge, F.G. | 登録日 | 2011-11-18 | 公開日 | 2012-01-25 | 最終更新日 | 2012-02-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Synthesis of New 4,5-Dihydrofuranoindoles and Their Evaluation as HCV NS5B Polymerase Inhibitors. Org.Lett., 14, 2012
|
|
3USR
| Structure of Y194F glycogenin mutant truncated at residue 270 | 分子名称: | CHLORIDE ION, GLYCEROL, Glycogenin-1 | 著者 | Issoglio, F.M, Carrizo, M.E, Romero, J.M, Curtino, J.A. | 登録日 | 2011-11-23 | 公開日 | 2011-12-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mechanisms of monomeric and dimeric glycogenin autoglucosylation. J.Biol.Chem., 287, 2012
|
|
3V2T
| |
3TTE
| Crystal structure of enolase brado_4202 (target EFI-501651) from Bradyrhizobium complexed with magnesium and mandelic acid | 分子名称: | (S)-MANDELIC ACID, FORMIC ACID, GLYCEROL, ... | 著者 | Patskovsky, Y, Kim, J, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammond, J, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2011-09-14 | 公開日 | 2011-09-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Mandelate Racemase from Bradyrhizobium Sp. Ors278 To be Published
|
|
3TOT
| Crystal structure of GLUTATHIONE TRANSFERASE (TARGET EFI-501058) from Ralstonia solanacearum GMI1000 | 分子名称: | ACETATE ION, Glutathione s-transferase protein | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Zencheck, W.D, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2011-09-06 | 公開日 | 2011-09-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Crystal structure of GLUTATHIONE S-TRANSFERASE from Ralstonia solanacearum To be Published
|
|
3UJ2
| CRYSTAL STRUCTURE OF AN ENOLASE FROM ANAEROSTIPES CACCAE (EFI TARGET EFI-502054) WITH BOUND MG AND SULFATE | 分子名称: | Enolase 1, MAGNESIUM ION, SULFATE ION | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Hillerich, B, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2011-11-07 | 公開日 | 2011-11-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | CRYSTAL STRUCTURE OF AN ENOLASE FROM ANAEROSTIPES CACCAE (EFI TARGET EFI-502054) WITH BOUND MG AND SULFATE to be published
|
|
3UIZ
| |
3US9
| Crystal Structure of the NCX1 Intracellular Tandem Calcium Binding Domains(CBD12) | 分子名称: | CALCIUM ION, Sodium/calcium exchanger 1 | 著者 | Giladi, M, Sasson, Y, Hirsch, J.A, Khananshvili, D. | 登録日 | 2011-11-23 | 公開日 | 2012-07-11 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | A common Ca2+-driven interdomain module governs eukaryotic NCX regulation. Plos One, 7, 2012
|
|
3V1P
| Crystal structure of the mutant Q185A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP | 分子名称: | 6-HYDROXYURIDINE-5'-PHOSPHATE, Orotidine 5'-phosphate decarboxylase, SULFATE ION | 著者 | Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C. | 登録日 | 2011-12-09 | 公開日 | 2012-11-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry, 51, 2012
|
|
3V3W
| Crystal structure of an enolase from the soil bacterium Cellvibrio japonicus (TARGET EFI-502161) with bound MG and glycerol | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CHLORIDE ION, GLYCEROL, ... | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Wasserman, S.R, Morisco, L.L, Sojitra, S, Seidel, R, Hillerich, B, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2011-12-14 | 公開日 | 2012-01-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal structure of an enolase from the soil bacterium Cellvibrio japonicus (TARGET EFI-502161) with bound MG and glycerol to be published
|
|
3V4B
| Crystal structure of an enolase from the soil bacterium Cellvibrio japonicus (TARGET EFI-502161) with bound MG and L-tartrate | 分子名称: | CHLORIDE ION, L(+)-TARTARIC ACID, MAGNESIUM ION, ... | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Wasserman, S.R, Morisco, L.L, Sojitra, S, Seidel, R.D, Hillerich, B, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Al Obaidi, N, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2011-12-14 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal structure of an enolase from the soil bacterium Cellvibrio japonicus (TARGET EFI-502161) with bound MG and l-tartrate to be published
|
|
3V5F
| Crystal structure of the mutant E234A of Galacturonate Dehydratase from GEOBACILLUS SP. complexed with Mg | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, Mandelate racemase/muconate lactonizing protein | 著者 | Fedorov, A.A, Fedorov, E.V, Groninger-Poe, F, Gerlt, J.A, Almo, S.C. | 登録日 | 2011-12-16 | 公開日 | 2012-12-19 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the mutant E234A of Galacturonate Dehydratase from GEOBACILLUS SP. complexed with Mg To be Published
|
|
3VHJ
| |