7DV7
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7D2T
| Crystal structure of Rsu1/PINCH1_LIM45C complex | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, ... | 著者 | Yang, H, Wei, Z, Yu, C. | 登録日 | 2020-09-17 | 公開日 | 2021-02-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics. Elife, 10, 2021
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7D2S
| Crystal structure of Rsu1/PINCH1_LIM5C complex | 分子名称: | GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, Ras suppressor protein 1, ... | 著者 | Yang, H, Wei, Z, Cong, Y. | 登録日 | 2020-09-17 | 公開日 | 2021-02-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.653 Å) | 主引用文献 | Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics. Elife, 10, 2021
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7D2U
| Crystal structure of Rsu1/PINCH1_LIM45C complex | 分子名称: | GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, MALONATE ION, ... | 著者 | Yang, H, Wei, Z, Cong, Y. | 登録日 | 2020-09-17 | 公開日 | 2021-02-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics. Elife, 10, 2021
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7VRE
| The crystal structure of EGFR T790M/C797S with the inhibitor HCD2892 | 分子名称: | 5-chloranyl-N-[5-chloranyl-2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-4-(1-ethylsulfonylindol-3-yl)pyrimidin-2-amine, Epidermal growth factor receptor | 著者 | Zhu, S.J. | 登録日 | 2021-10-22 | 公開日 | 2022-06-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.507 Å) | 主引用文献 | Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-Generation Epidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations. J.Med.Chem., 65, 2022
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7VRA
| The crystal structure of EGFR T790M/C797S with the inhibitor HC5476 | 分子名称: | 25-chloro-11-(ethylsulfonyl)-44-morpholino-11H-5,12-dioxa-3-aza-1(3,6)-indola-2(4,2)-pyrimidina-4(1,3)-benzenacyclododecaphane, Epidermal growth factor receptor | 著者 | Zhu, S.J. | 登録日 | 2021-10-22 | 公開日 | 2022-06-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-Generation Epidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations. J.Med.Chem., 65, 2022
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7XMV
| E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A(AMP/ADP) filament bound with ADP, AMP and R5P | 分子名称: | 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Hu, H.H, Lu, G.M, Chang, C.C, Liu, J.L. | 登録日 | 2022-04-27 | 公開日 | 2022-06-29 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Filamentation modulates allosteric regulation of PRPS. Elife, 11, 2022
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7XN3
| E.coli phosphoribosylpyrophosphate (PRPP) synthetase type B filament bound with Pi | 分子名称: | PHOSPHATE ION, Ribose-phosphate pyrophosphokinase | 著者 | Hu, H.H, Lu, G.M, Chang, C.C, Liu, J.L. | 登録日 | 2022-04-27 | 公開日 | 2022-06-29 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Filamentation modulates allosteric regulation of PRPS. Elife, 11, 2022
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7XMU
| E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A filament bound with ADP, Pi and R5P | 分子名称: | 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Hu, H.H, Lu, G.M, Chang, C.C, Liu, J.L. | 登録日 | 2022-04-26 | 公開日 | 2022-06-29 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Filamentation modulates allosteric regulation of PRPS. Elife, 11, 2022
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7X9X
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7XA4
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7XA2
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7XOZ
| Crystal structure of RPPT-TIR | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase | 著者 | Song, W, Jia, A, Huang, S, Chai, J. | 登録日 | 2022-05-02 | 公開日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | TIR-catalyzed ADP-ribosylation reactions produce signaling molecules for plant immunity. Science, 377, 2022
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7XJP
| Cryo-EM structure of EDS1 and SAG101 with ATP-APDR | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ADENOSINE-5-DIPHOSPHORIBOSE, ISOPROPYL ALCOHOL, ... | 著者 | Huang, S.J, Jia, A.L, Han, Z.F, Chai, J.J. | 登録日 | 2022-04-18 | 公開日 | 2022-07-20 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | 主引用文献 | TIR-catalyzed ADP-ribosylation reactions produce signaling molecules for plant immunity. Science, 377, 2022
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7WBI
| BF2*1901-FLU | 分子名称: | Beta-2-microglobulin, ILE-ARG-HIS-GLU-ASN-ARG-MET-VAL-LEU, MHC class I alpha chain 2 | 著者 | Liu, W.J. | 登録日 | 2021-12-16 | 公開日 | 2022-12-21 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A Wider and Deeper Peptide-Binding Groove for the Class I Molecules from B15 Compared with B19 Chickens Correlates with Relative Resistance to Marek's Disease. J Immunol., 210, 2023
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7WBG
| BF2*1901/RY8 | 分子名称: | ARG-ARG-ARG-GLU-GLN-THR-ASP-TYR, Beta-2-microglobulin, MHC class I alpha chain 2 | 著者 | Liu, W.J. | 登録日 | 2021-12-16 | 公開日 | 2022-12-21 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Wider and Deeper Peptide-Binding Groove for the Class I Molecules from B15 Compared with B19 Chickens Correlates with Relative Resistance to Marek's Disease. J Immunol., 210, 2023
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7YK1
| Structural basis of human PRPS2 filaments | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Lu, G.M, Hu, H.H, Liu, J.L. | 登録日 | 2022-07-21 | 公開日 | 2023-08-02 | 最終更新日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Structural basis of human PRPS2 filaments. Cell Biosci, 13, 2023
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7WXH
| GPR domain open form of Drosophila P5CS filament with glutamate, ATP, and NADPH | 分子名称: | Delta-1-pyrroline-5-carboxylate synthase | 著者 | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | 登録日 | 2022-02-14 | 公開日 | 2022-03-30 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural basis of dynamic P5CS filaments. Elife, 11, 2022
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7WXG
| GPR domain closed form of Drosophila P5CS filament with glutamate, ATP, and NADPH | 分子名称: | Delta-1-pyrroline-5-carboxylate synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | 登録日 | 2022-02-14 | 公開日 | 2022-03-30 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural basis of dynamic P5CS filaments. Elife, 11, 2022
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7WXI
| GPR domain of Drosophila P5CS filament with glutamate and ATPgammaS | 分子名称: | Delta-1-pyrroline-5-carboxylate synthase, GAMMA-GLUTAMYL PHOSPHATE | 著者 | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | 登録日 | 2022-02-14 | 公開日 | 2022-03-30 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural basis of dynamic P5CS filaments. Elife, 11, 2022
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7WXF
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7WX4
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7WX3
| GK domain of Drosophila P5CS filament with glutamate, ATP, and NADPH | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Delta-1-pyrroline-5-carboxylate synthase, GAMMA-GLUTAMYL PHOSPHATE, ... | 著者 | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | 登録日 | 2022-02-14 | 公開日 | 2022-04-06 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of dynamic P5CS filaments. Elife, 11, 2022
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