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8V4U
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BU of 8v4u by Molmil
Structure of SARS-CoV-2 main protease in complex with a covalent inhibitor
分子名称: 3C-like proteinase nsp5, N-(methoxycarbonyl)-3-methyl-L-valyl-(4R)-N-{(1Z,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-4-(trifluoromethyl)-L-prolinamide
著者Greasley, S.E, Ferre, R.A, Liu, W.
登録日2023-11-29
公開日2024-05-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.819 Å)
主引用文献A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19.
J.Med.Chem., 67, 2024
8XFB
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BU of 8xfb by Molmil
Cryo-EM structure of partial dimeric WDR11-FAM91A1 complex
分子名称: Protein FAM91A1, WD repeat-containing protein 11
著者Jia, G.W, Deng, Q.H, Su, Z.M, Jia, D.
登録日2023-12-13
公開日2024-08-14
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献The WDR11 complex is a receptor for acidic-cluster-containing cargo proteins.
Cell, 187, 2024
7XYD
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BU of 7xyd by Molmil
Crystal structure of TMPRSS2 in complex with Nafamostat
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ...
著者Wang, H, Liu, X, Duan, Y, Liu, X, Sun, L, Yang, H.
登録日2022-06-01
公開日2023-12-06
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
7Y0F
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BU of 7y0f by Molmil
Crystal structure of TMPRSS2 in complex with UK-371804
分子名称: 2-[(1-carbamimidamido-4-chloranyl-isoquinolin-7-yl)sulfonylamino]-2-methyl-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Wang, H, Duan, Y, Liu, X, Sun, L, Yang, H.
登録日2022-06-04
公開日2023-12-06
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
7Y0E
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BU of 7y0e by Molmil
Crystal structure of TMPRSS2 in complex with Camostat
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ...
著者Wang, H, Duan, Y, Liu, X, Sun, L, Yang, H.
登録日2022-06-04
公開日2023-12-06
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
8GU7
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BU of 8gu7 by Molmil
Selective targeting of the Beclin 2-Atg14L coiled coil complex by stapled peptides promotes autophagy and endolysosomal trafficking of GPCRs
分子名称: Beclin 1-associated autophagy-related key regulator, Beclin-2
著者Qiu, X, Zhao, Y.
登録日2022-09-11
公開日2023-07-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The potent BECN2-ATG14 coiled-coil interaction is selectively critical for endolysosomal degradation of GPRASP1/GASP1-associated GPCRs.
Autophagy, 19, 2023
8ID0
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BU of 8id0 by Molmil
Crystal structure of PflD bound to 1,5-anhydromannitol-6-phosphate in Streptococcus dysgalactiae subsp. equisimilis
分子名称: [(2R,3S,4R,5R)-3,4,5-tris(oxidanyl)oxan-2-yl]methyl dihydrogen phosphate, formate C-acetyltransferase
著者Ma, K.L, Zhang, Y.
登録日2023-02-11
公開日2024-10-02
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献A Widespread Radical-Mediated Glycolysis Pathway.
J.Am.Chem.Soc., 146, 2024
8ID7
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BU of 8id7 by Molmil
Crystal structure of YbiW in complex with 1,5-anhydroglucitol-6-phosphate in Escherichia coli
分子名称: 1,5-anhydro-6-O-phosphono-D-glucitol, Probable dehydratase YbiW
著者Ma, K.L, Zhang, Y.
登録日2023-02-12
公開日2024-10-02
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献A Widespread Radical-Mediated Glycolysis Pathway.
J.Am.Chem.Soc., 146, 2024
7Y55
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BU of 7y55 by Molmil
Crystal structure of a glutathione S-transferase Tau1 from Pinus densata in complex with GSH
分子名称: GLUTATHIONE, PdGSTU1
著者Qu, C, Zeng, Q.Y.
登録日2022-06-16
公開日2022-12-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.19113064 Å)
主引用文献Functional significance of asymmetrical retention of parental alleles in a hybrid pine species complex
J Syst Evol, n/a, 2023
7DMW
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BU of 7dmw by Molmil
Crystal structure of CcpC regulatory domain in complex with citrate from Bacillus amyloliquefaciens
分子名称: CITRATE ANION, CcpC
著者Chen, J, Wang, L, Shang, F, Liu, W, Chen, Y, Lan, J, Bu, T, Bai, X, Xu, Y.
登録日2020-12-08
公開日2021-10-27
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Functional and structural analysis of catabolite control protein C that responds to citrate.
Sci Rep, 11, 2021
6JK8
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BU of 6jk8 by Molmil
Cryo-EM structure of the full-length human IGF-1R in complex with insulin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin, ...
著者Zhang, X, Yu, D, Wang, T.
登録日2019-02-27
公開日2020-03-04
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Visualization of Ligand-Bound Ectodomain Assembly in the Full-Length Human IGF-1 Receptor by Cryo-EM Single-Particle Analysis.
Structure, 28, 2020
7DPD
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BU of 7dpd by Molmil
Human MCM9 N-terminal domain
分子名称: DNA helicase MCM9, SODIUM ION, ZINC ION
著者Li, J, Liu, L, Liu, Y.
登録日2020-12-18
公開日2021-05-19
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural study of the N-terminal domain of human MCM8/9 complex.
Structure, 29, 2021
7DP3
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BU of 7dp3 by Molmil
Human MCM8 N-terminal domain
分子名称: DNA helicase MCM8, ZINC ION
著者Li, J, Liu, L, Liu, Y.
登録日2020-12-17
公開日2021-05-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural study of the N-terminal domain of human MCM8/9 complex.
Structure, 29, 2021

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件を2024-11-06に公開中

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