6K9K
 
 | | Monomeric human ATM (Ataxia telangiectasia mutated) kinase | | 分子名称: | Serine-protein kinase ATM | | 著者 | Xiao, J, Liu, M, Qi, Y, Yuriy, C, Zhang, P, Xu, Y. | | 登録日 | 2019-06-16 | | 公開日 | 2019-12-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (7.82 Å) | | 主引用文献 | Structural insights into the activation of ATM kinase.
Cell Res., 29, 2019
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1VRY
 | | Second and Third Transmembrane Domains of the Alpha-1 Subunit of Human Glycine Receptor | | 分子名称: | Glycine receptor alpha-1 chain | | 著者 | Ma, D, Liu, Z, Li, L, Tang, P, Xu, Y. | | 登録日 | 2005-07-20 | | 公開日 | 2005-07-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and Dynamics of the Second and Third Transmembrane Domains of Human Glycine Receptor.
Biochemistry, 44, 2005
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1TF7
 | | Crystal Structure of Circadian Clock Protein KaiC | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, KaiC | | 著者 | Pattanayek, R, Wang, J, Mori, T, Xu, Y, Johnson, C.H, Egli, M. | | 登録日 | 2004-05-26 | | 公開日 | 2004-08-24 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Visualizing a Circadian Clock Protein; Crystal Structure of KaiC and Functional Insights
Mol.Cell, 15, 2004
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3RQW
 | | Crystal structure of acetylcholine bound to a prokaryotic pentameric ligand-gated ion channel, ELIC | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETYLCHOLINE, ELIC Pentameric Ligand Gated Ion Channel from Erwinia Chrysanthemi, ... | | 著者 | Pan, J.J, Chen, Q, Yoshida, K, Cohen, A, Kong, X.P, Xu, Y, Tang, P. | | 登録日 | 2011-04-28 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.913 Å) | | 主引用文献 | Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine.
Nat Commun, 3, 2012
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3RQU
 | | Crystal structure of a prokaryotic pentameric ligand-gated ion channel, ELIC | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ELIC Pentameric Ligand Gated Ion Channel from Erwinia Chrysanthemi, GLYCEROL | | 著者 | Pan, J.J, Chen, Q, Yoshida, K, Cohen, A, Kong, X.P, Xu, Y, Tang, P. | | 登録日 | 2011-04-28 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.089 Å) | | 主引用文献 | Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine.
Nat Commun, 3, 2012
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5IL3
 | | Tobacco 5-epi-aristolochene synthase with MOPSO buffer molecule and Mg2+ ions | | 分子名称: | (2R)-2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonic acid, (2S)-2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonic acid, 5-epi-aristolochene synthase, ... | | 著者 | Koo, H.J, Louie, G.V, Xu, Y, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-04 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Small-molecule buffer components can directly affect terpene-synthase activity by interacting with the substrate-binding site of the enzyme
To Be Published
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5ILH
 | | Tobacco 5-epi-aristolochene synthase with CAPSO buffer molecule and Ca2+ ions | | 分子名称: | (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 5-epi-aristolochene synthase, ... | | 著者 | Koo, H.J, Louie, G.V, Xu, Y, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-04 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Small-molecule buffer components can directly affect terpene-synthase activity by interacting with the substrate-binding site of the enzyme
To Be Published
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5IK6
 | | Tobacco 5-epi-aristolochene synthase with germacrene A and PPi | | 分子名称: | 5-epi-aristolochene synthase, DIPHOSPHATE, GERMACRENE A, ... | | 著者 | Koo, H.J, Xu, Y, Louie, G.V, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-03 | | 公開日 | 2016-10-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants.
J.Antibiot., 69, 2016
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5IKA
 | | Tobacco 5-epi-aristolochene synthase with PPi | | 分子名称: | 5-epi-aristolochene synthase, DIPHOSPHATE, MAGNESIUM ION | | 著者 | Koo, H.J, Xu, Y, Louie, G.V, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-03 | | 公開日 | 2016-10-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants.
J.Antibiot., 69, 2016
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5IL8
 | | Tobacco 5-epi-aristolochene synthase with MOPSO buffer molecule and Ca2+ ions | | 分子名称: | (2R)-2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonic acid, (2S)-2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonic acid, 5-epi-aristolochene synthase, ... | | 著者 | Koo, H.J, Louie, G.V, Xu, Y, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-04 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Small-molecule buffer components can directly affect terpene-synthase activity by interacting with the substrate-binding site of the enzyme
To Be Published
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5ILJ
 | | Tobacco 5-epi-aristolochene synthase with BIS-TRIS buffer molecule | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-epi-aristolochene synthase | | 著者 | Koo, H.J, Louie, G.V, Xu, Y, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-04 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Small-molecule buffer components can directly affect terpene-synthase activity by interacting with the substrate-binding site of the enzyme
To Be Published
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5ILZ
 | | Tobacco 5-epi-aristolochene synthase with BIS-TRIS propane (BTP) buffer molecule | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-epi-aristolochene synthase | | 著者 | Koo, H.J, Louie, G.V, Xu, Y, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-05 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Small-molecule buffer components can directly affect terpene-synthase activity by interacting with the substrate-binding site of the enzyme
To Be Published
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5ILK
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5ILY
 | | Tobacco 5-epi-aristolochene synthase with BIS-TRIS buffer molecule and diphosphate (PPi) | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-epi-aristolochene synthase, DIPHOSPHATE, ... | | 著者 | Koo, H.J, Louie, G.V, Xu, Y, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-05 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Small-molecule buffer components can directly affect terpene-synthase activity by interacting with the substrate-binding site of the enzyme
To Be Published
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5IK0
 | | Tobacco 5-epi-aristolochene synthase with FPP | | 分子名称: | 5-epi-aristolochene synthase, FARNESYL DIPHOSPHATE, MAGNESIUM ION | | 著者 | Koo, H.J, Xu, Y, Louie, G.V, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-03 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants.
J.Antibiot., 69, 2016
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5IK9
 | | Tobacco 5-epi-aristolochene with farnesyl monophosphate | | 分子名称: | (2E,6Z)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl dihydrogen phosphate, 5-epi-aristolochene synthase, MAGNESIUM ION | | 著者 | Koo, H.J, Xu, Y, Louie, G.V, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-03 | | 公開日 | 2016-10-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants.
J.Antibiot., 69, 2016
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5ILI
 | | Tobacco 5-epi-aristolochene synthase with CAPSO buffer molecule and Mg2+ ions | | 分子名称: | (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 5-epi-aristolochene synthase, ... | | 著者 | Koo, H.J, Louie, G.V, Xu, Y, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-04 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Small-molecule buffer components can directly affect terpene-synthase activity by interacting with the substrate-binding site of the enzyme
To Be Published
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5H64
 | | Cryo-EM structure of mTORC1 | | 分子名称: | Regulatory-associated protein of mTOR, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8 | | 著者 | Yang, H, Wang, J, Liu, M, Chen, X, Huang, M, Tan, D, Dong, M, Wong, C.C.L, Wang, J, Xu, Y, Wang, H. | | 登録日 | 2016-11-10 | | 公開日 | 2017-01-25 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | 4.4 angstrom Resolution Cryo-EM structure of human mTOR Complex 1
Protein Cell, 7, 2016
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5IM1
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5ILD
 | | Tobacco 5-epi-aristolochene synthase with MES buffer molecule and Mg2+ ions | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-epi-aristolochene synthase, MAGNESIUM ION | | 著者 | Koo, H.J, Louie, G.V, Xu, Y, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-04 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Small-molecule buffer components can directly affect terpene-synthase activity by interacting with the substrate-binding site of the enzyme
To Be Published
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6IGM
 | | Cryo-EM Structure of Human SRCAP Complex | | 分子名称: | Actin-related protein 6, Helicase SRCAP, RuvB-like 1, ... | | 著者 | Feng, Y, Tian, Y, Wu, Z, Xu, Y. | | 登録日 | 2018-09-25 | | 公開日 | 2019-07-24 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cryo-EM structure of human SRCAP complex.
Cell Res., 28, 2018
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5TIH
 | | Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA | | 分子名称: | ACETATE ION, CyRPA antibody Fab Heavy Chain, CyRPA antibody Fab Light Chain, ... | | 著者 | Chen, L, Xu, Y, Wang, W, Thompson, J.K, Goddard-Borger, E, Lawrence, M.C, Cowman, A.F. | | 登録日 | 2016-10-03 | | 公開日 | 2017-03-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Structural basis for inhibition of erythrocyte invasion by antibodies toPlasmodium falciparumprotein CyRPA.
Elife, 6, 2017
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2LLY
 | | NMR structures of the transmembrane domains of the nAChR a4 subunit | | 分子名称: | Neuronal acetylcholine receptor subunit alpha-4 | | 著者 | Bondarenko, V, Mowrey, D, Tillman, T, Cui, T, Liu, L.T, Xu, Y, Tang, P. | | 登録日 | 2011-11-18 | | 公開日 | 2012-03-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structures of the transmembrane domains of the a4b2 nAChR.
Biochim.Biophys.Acta, 1818, 2012
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2LM2
 | | NMR structures of the transmembrane domains of the AChR b2 subunit | | 分子名称: | Neuronal acetylcholine receptor subunit beta-2 | | 著者 | Bondarenko, V, Mowrey, D, Tillman, T, Cui, T, Liu, L.T, Xu, Y, Tang, P. | | 登録日 | 2011-11-18 | | 公開日 | 2012-03-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structures of the transmembrane domains of the a4b2 nAChR.
Biochim.Biophys.Acta, 1818, 2012
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2MAW
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