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4H6J
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BU of 4h6j by Molmil
Identification of Cys 255 in HIF-1 as a novel site for development of covalent inhibitors of HIF-1 /ARNT PasB domain protein-protein interaction.
分子名称: ARYL HYDROCARBON NUCLEAR TRANSLOCATOR, HYPOXIA INDUCIBLE FACTOR 1-ALPHA
著者Cardoso, R, Love, R.A, Nilsson, C, Bergqvist, S, Nowlin, D, Yan, J, Liu, K, Zhu, J, Chen, P, Deng, Y.-L, Dyson, H.J, Greig, M.J, Brooun, A.
登録日2012-09-19
公開日2012-12-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Identification of Cys255 in HIF-1 alpha as a novel site for development of covalent inhibitors of HIF-1 alpha /ARNT PasB domain protein-protein interaction.
Protein Sci., 21, 2012
5O5C
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BU of 5o5c by Molmil
The crystal structure of DfoJ, the desferrioxamine biosynthetic pathway lysine decarboxylase from the fire blight disease pathogen Erwinia amylovora
分子名称: PYRIDOXAL-5'-PHOSPHATE, Putative decarboxylase involved in desferrioxamine biosynthesis
著者Salomone-Stagni, M, Bartho, J.D, Polsinelli, I, Bellini, D, Walsh, M.A, Demitri, N, Benini, S.
登録日2017-06-01
公開日2018-02-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A complete structural characterization of the desferrioxamine E biosynthetic pathway from the fire blight pathogen Erwinia amylovora.
J. Struct. Biol., 202, 2018
5O8R
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The crystal structure of DfoA bound to FAD and NADP; the desferrioxamine biosynthetic pathway cadaverine monooxygenase from the fire blight disease pathogen Erwinia amylovora
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, L-lysine 6-monooxygenase involved in desferrioxamine biosynthesis, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Salomone-Stagni, M, Bartho, J.D, Polsinelli, I, Bellini, D, Walsh, M.A, Demitri, N, Benini, S.
登録日2017-06-14
公開日2018-02-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A complete structural characterization of the desferrioxamine E biosynthetic pathway from the fire blight pathogen Erwinia amylovora.
J. Struct. Biol., 202, 2018
4AZ3
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crystal structure of cathepsin a, complexed with 15a
分子名称: (3S)-3-({[1-(2-fluorophenyl)-5-{[(2R)-2-hydroxy-3,3-dimethylbutyl]oxy}-1H-pyrazol-3-yl]carbonyl}amino)-3-(2-methylphenyl)propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ...
著者Ruf, S, Buning, C, Schreuder, H, Horstick, G, Linz, W, Olpp, T, Pernerstorfer, J, Hiss, K, Kroll, K, Kannt, A, Kohlmann, M, Linz, D, Huebschle, T, Ruetten, H, Wirth, K, Schmidt, T, Sadowski, T.
登録日2012-06-22
公開日2012-09-26
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Novel Beta-Amino Acid Derivatives as Inhibitors of Cathepsin A.
J.Med.Chem., 55, 2012
2IUB
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BU of 2iub by Molmil
Crystal structure of a divalent metal ion transporter CorA at 2.9 A resolution.
分子名称: CHLORIDE ION, DIVALENT CATION TRANSPORT-RELATED PROTEIN, MAGNESIUM ION
著者Eshaghi, S, Niegowski, D, Kohl, A, Martinez Molina, D, Lesley, S.A, Nordlund, P.
登録日2006-06-01
公開日2006-08-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure of a Divalent Metal Ion Transporter Cora at 2.9 Angstrom Resolution.
Science, 313, 2006
2BF0
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BU of 2bf0 by Molmil
crystal structure of the rpr of pcf11
分子名称: CALCIUM ION, PCF11
著者Noble, C.G, Hollingworth, D, Martin, S.R, Adeniran, V.E, Smerdon, S.J, Kelly, G, Taylor, I.A, Ramos, A.
登録日2004-12-02
公開日2005-01-18
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Key Features of the Interaction between Pcf11 Cid and RNA Polymerase II Ctd.
Nat.Struct.Mol.Biol., 12, 2005
4AZ0
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BU of 4az0 by Molmil
crystal structure of cathepsin a, complexed with 8a.
分子名称: (S)-3-{[1-(2-Fluoro-phenyl)-5-hydroxy-1H-pyrazole-3-carbonyl]-amino}-3-o-tolyl-propionic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ...
著者Ruf, S, Buning, C, Schreuder, H, Horstick, G, Linz, W, Olpp, T, Pernerstorfer, J, Hiss, K, Kroll, K, Kannt, A, Kohlmann, M, Linz, D, Huebschle, T, Ruetten, H, Wirth, K, Schmidt, T, Sadowski, T.
登録日2012-06-22
公開日2012-09-26
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Novel Beta-Amino Acid Derivatives as Inhibitors of Cathepsin A.
J.Med.Chem., 55, 2012
2BKD
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BU of 2bkd by Molmil
Structure of the N-terminal domain of Fragile X Mental Retardation Protein
分子名称: Fragile X messenger ribonucleoprotein 1
著者Ramos, A, Hollingworth, D, Adinolfi, S, Castets, M, Kelly, G, Frenkiel, T.A, Bardoni, B, Pastore, A.
登録日2005-02-15
公開日2006-01-18
最終更新日2024-11-06
実験手法SOLUTION NMR
主引用文献The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction.
Structure, 14, 2006
4B8T
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BU of 4b8t by Molmil
RNA BINDING PROTEIN Solution structure of the third KH domain of KSRP in complex with the G-rich target sequence.
分子名称: 5'-R(*AP*GP*GP*GP*UP)-3', KH-TYPE SPLICING REGULATORY PROTEIN
著者Nicastro, G, Garcia-Mayoral, M.F, Hollingworth, D, Kelly, G, Martin, S.R, Briata, P, Gherzi, R, Ramos, A.
登録日2012-08-30
公開日2012-11-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Noncanonical G Recognition Mediates Ksrp Regulation of Let-7 Biogenesis
Nat.Struct.Mol.Biol., 19, 2012
1Z3H
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BU of 1z3h by Molmil
The exportin Cse1 in its cargo-free, cytoplasmic state
分子名称: Importin alpha re-exporter, MAGNESIUM ION
著者Cook, A, Fernandez, E, Lindner, D, Ebert, J, Schlenstedt, G, Conti, E.
登録日2005-03-12
公開日2005-05-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The structure of the nuclear export receptor cse1 in its cytosolic state reveals a closed conformation incompatible with cargo binding
Mol.Cell, 18, 2005
5O7O
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BU of 5o7o by Molmil
The crystal structure of DfoC, the desferrioxamine biosynthetic pathway acetyltransferase/Non-Ribosomal Peptide Synthetase (NRPS)-Independent Siderophore (NIS) from the fire blight disease pathogen Erwinia amylovora
分子名称: Desferrioxamine siderophore biosynthesis protein dfoC
著者Salomone-Stagni, M, Bartho, J.D, Polsinelli, I, Bellini, D, Walsh, M.A, Demitri, N, Benini, S.
登録日2017-06-09
公開日2018-02-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献A complete structural characterization of the desferrioxamine E biosynthetic pathway from the fire blight pathogen Erwinia amylovora.
J. Struct. Biol., 202, 2018
2JVZ
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BU of 2jvz by Molmil
Solution NMR Structure of the Second and Third KH Domains of KSRP
分子名称: Far upstream element-binding protein 2
著者Diaz-Moreno, I, Hollingworth, D, Garcia-Mayoral, M.F, Kelly, G, Cukier, C.D, Ramos, A.
登録日2007-09-28
公開日2009-02-17
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of the Second and Third KH Domains of KSRP
To be Published, 2007
5O3Z
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BU of 5o3z by Molmil
Crystal structure of Sorbitol-6-Phosphate 2-dehydrogenase SrlD from Erwinia amylovora
分子名称: CHLORIDE ION, Sorbitol-6-phosphate dehydrogenase
著者Salomone-Stagni, M, Bartho, J.D, Bellini, D, Walsh, M.A, Benini, S.
登録日2017-05-25
公開日2018-06-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structural and functional analysis of Erwinia amylovora SrlD. The first crystal structure of a sorbitol-6-phosphate 2-dehydrogenase.
J.Struct.Biol., 203, 2018
5O8P
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BU of 5o8p by Molmil
The crystal structure of DfoA bound to FAD, the desferrioxamine biosynthetic pathway cadaverine monooxygenase from the fire blight disease pathogen Erwinia amylovora
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, L-lysine 6-monooxygenase involved in desferrioxamine biosynthesis
著者Salomone-Stagni, M, Bartho, J.D, Polsinelli, I, Bellini, D, Walsh, M.A, Demitri, N, Benini, S.
登録日2017-06-14
公開日2018-06-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献A complete structural characterization of the desferrioxamine E biosynthetic pathway from the fire blight pathogen Erwinia amylovora.
J.Struct.Biol., 202, 2018
2N8L
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BU of 2n8l by Molmil
Zipcode-binding-protein-1 KH3KH4(DD) domains in complex with the KH3 RNA target
分子名称: Insulin-like growth factor 2 mRNA-binding protein 1, RNA (5'-R(P*GP*CP*AP*CP*AP*CP*CP*C)-3')
著者Nicastro, G, Candel, A.M, Ramos, A, Hollingworth, D.
登録日2015-10-21
公開日2017-01-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Zipcode-binding-protein-1 KH3KH4(DD) domains in complex with the RNA target GCACACCC
To be Published
2N8M
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BU of 2n8m by Molmil
Zipcode-binding-protein-1 KH3(DD)KH4 domains in complex with the KH4 RNA target
分子名称: Insulin-like growth factor 2 mRNA-binding protein 1, RNA (5'-R(P*UP*CP*GP*GP*AP*CP*U)-3')
著者Nicastro, G, Ramos, A, Candel, A, Hollingworth, D.
登録日2015-10-21
公開日2017-01-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Zipcode-binding-protein-1 KH3(DD)KH4 domains in complex with the RNA target UCGGACU
To be Published
3WQA
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BU of 3wqa by Molmil
Acinetobacter sp. Tol 5 AtaA YDD-DALL3 domains in C-terminal stalk fused to GCN4 adaptors (CstalkC1ii)
分子名称: CHLORIDE ION, NICKEL (II) ION, PHOSPHATE ION, ...
著者Koiwai, K, Hartmann, M.D, Yoshimoto, S, Nur 'Izzah, N, Suzuki, A, Linke, D, Lupas, A.N, Hori, K.
登録日2014-01-24
公開日2015-03-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Structural Basis for Toughness and Flexibility in the C-terminal Passenger Domain of an Acinetobacter Trimeric Autotransporter Adhesin.
J.Biol.Chem., 291, 2016
3WPR
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Acinetobacter sp. Tol 5 AtaA N-terminal half of C-terminal stalk fused to GCN4 adaptors (CstalkN)
分子名称: Trimeric autotransporter adhesin
著者Koiwai, K, Hartmann, M.D, Yoshimoto, S, Nur 'Izzah, N, Suzuki, A, Linke, D, Lupas, A.N, Hori, K.
登録日2014-01-15
公開日2015-03-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.899 Å)
主引用文献Structural Basis for Toughness and Flexibility in the C-terminal Passenger Domain of an Acinetobacter Trimeric Autotransporter Adhesin.
J.Biol.Chem., 291, 2016
4AE8
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Crystal structure of human THEM4
分子名称: THIOESTERASE SUPERFAMILY MEMBER 4
著者Zhuravleva, E, Gut, H, Hynx, D, Marcellin, D, Bleck, C.K.E, Genoud, C, Cron, P, Keusch, J.J, Dummler, B, Degli Esposti, M, Hemmings, B.A.
登録日2012-01-09
公開日2012-07-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.594 Å)
主引用文献Acyl Coenzyme a Thioesterase Them5/Acot15 is Involved in Cardiolipin Remodeling and Fatty Liver Development.
Mol.Cell.Biol., 32, 2012
4AE7
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Crystal structure of human THEM5
分子名称: THIOESTERASE SUPERFAMILY MEMBER 5
著者Zhuravleva, E, Gut, H, Hynx, D, Marcellin, D, Bleck, C.K.E, Genoud, C, Cron, P, Keusch, J.J, Dummler, B, Degli Esposti, M, Hemmings, B.A.
登録日2012-01-09
公開日2012-07-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Acyl Coenzyme a Thioesterase Them5/Acot15 is Involved in Cardiolipin Remodeling and Fatty Liver Development.
Mol.Cell.Biol., 32, 2012
2MPW
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BU of 2mpw by Molmil
Solution structure of the LysM region of the E. coli Intimin periplasmic domain
分子名称: Intimin
著者Coles, M, Chaubey, M, Leo, J.C, Linke, D, Schuetz, M.C, Goetz, F, Autenrieth, I.B.
登録日2014-06-05
公開日2014-11-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Intimin periplasmic domain mediates dimerisation and binding to peptidoglycan.
Mol.Microbiol., 95, 2015
3WPP
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BU of 3wpp by Molmil
Acinetobacter sp. Tol 5 AtaA YDD-DALL3 domains in C-terminal stalk fused to GCN4 adaptors (CstalkC1iii)
分子名称: CHLORIDE ION, Trimeric autotransporter adhesin
著者Koiwai, K, Hartmann, M.D, Yoshimoto, S, Nur 'Izzah, N, Suzuki, A, Linke, D, Lupas, A.N, Hori, K.
登録日2014-01-15
公開日2015-03-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.952 Å)
主引用文献Structural Basis for Toughness and Flexibility in the C-terminal Passenger Domain of an Acinetobacter Trimeric Autotransporter Adhesin.
J.Biol.Chem., 291, 2016
2KXH
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Solution structure of the first two RRM domains of FIR in the complex with FBP Nbox peptide
分子名称: Poly(U)-binding-splicing factor PUF60, peptide of Far upstream element-binding protein 1
著者Cukier, C.D, Ramos, A, Hollingworth, D, Diaz-Moreno, I, Kelly, G.
登録日2010-05-05
公開日2010-08-18
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Molecular basis of FIR-mediated c-myc transcriptional control.
Nat.Struct.Mol.Biol., 17, 2010
2LME
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BU of 2lme by Molmil
Solid-state NMR structure of the membrane anchor domain of the trimeric autotransporter YadA
分子名称: Adhesin yadA
著者Shahid, S.A, Bardiaux, B, Franks, W.T, Habeck, M, Linke, D, van Rossum, B.
登録日2011-11-30
公開日2012-11-07
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Membrane-protein structure determination by solid-state NMR spectroscopy of microcrystals.
Nat.Methods, 9, 2012
2MVO
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Solution structure of the lantibiotic self-resistance lipoprotein MlbQ from Microbispora ATCC PTA-5024
分子名称: Putative lipoprotein
著者Pozzi, R, Schwartz, P, Linke, D, Kulik, A, Nega, M, Wohlleben, W, Stegmann, E, Coles, M.
登録日2014-10-09
公開日2015-07-15
最終更新日2024-11-06
実験手法SOLUTION NMR
主引用文献Distinct mechanisms contribute to immunity in the lantibiotic NAI-107 producer strain Microbispora ATCC PTA-5024.
Environ Microbiol, 18, 2016

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