4BB4
| ephB4 kinase domain inhibitor complex | 分子名称: | EPHRIN TYPE-B RECEPTOR 4, MAGNESIUM ION, N-(2-methoxyethyl)-4-[(6-pyridin-4-ylquinazolin-2-yl)amino]benzamide | 著者 | Read, J, Brassington, C.A, Green, I, McCall, E.J, Valentine, A.L. | 登録日 | 2012-09-19 | 公開日 | 2013-02-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Discovery and Optimization of a Novel Series of Potent Mutant B-Raf V600E Selective Kinase Inhibitors. J.Med.Chem., 56, 2013
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7C4X
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8DFM
| Ectodomain of full-length wild-type KIT-SCF dimers | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... | 著者 | Krimmer, S.G, Bertoletti, N, Mi, W, Schlessinger, J. | 登録日 | 2022-06-22 | 公開日 | 2023-03-29 | 最終更新日 | 2023-04-05 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention. Proc.Natl.Acad.Sci.USA, 120, 2023
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8DFP
| Ectodomain of full-length KIT(DupA502,Y503)-SCF dimers | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... | 著者 | Bertoletti, N, Krimmer, S.G, Mi, W, Schlessinger, J. | 登録日 | 2022-06-22 | 公開日 | 2023-03-29 | 最終更新日 | 2023-04-05 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention. Proc.Natl.Acad.Sci.USA, 120, 2023
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8DFQ
| Ectodomain of full-length KIT(T417I,delta418-419)-SCF dimers | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... | 著者 | Krimmer, S.G, Bertoletti, N, Mi, W, Schlessinger, J. | 登録日 | 2022-06-22 | 公開日 | 2023-03-29 | 最終更新日 | 2023-04-05 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention. Proc.Natl.Acad.Sci.USA, 120, 2023
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7VOU
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7X14
| Crystal structure of phospho-FFAT motif of MIGA2 bound to VAPB | 分子名称: | MIGA2 phospho FFAT motif, SULFATE ION, Vesicle-associated membrane protein-associated protein B | 著者 | Kim, H, Lee, C. | 登録日 | 2022-02-23 | 公開日 | 2022-09-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.675 Å) | 主引用文献 | Structural basis for mitoguardin-2 mediated lipid transport at ER-mitochondrial membrane contact sites. Nat Commun, 13, 2022
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7X15
| Crystal structure of MIGA2 LD targeting domain | 分子名称: | DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, FORMIC ACID, Mitoguardin 2 | 著者 | Kim, H, Lee, C. | 登録日 | 2022-02-23 | 公開日 | 2022-09-14 | 実験手法 | X-RAY DIFFRACTION (2.852 Å) | 主引用文献 | Structural basis for mitoguardin-2 mediated lipid transport at ER-mitochondrial membrane contact sites. Nat Commun, 13, 2022
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7VOV
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7VOX
| The crystal structure of human forkhead box protein A in complex with DNA 2 | 分子名称: | DNA (5'-D(P*AP*AP*AP*TP*AP*TP*TP*TP*AP*TP*TP*AP*TP*CP*GP*A)-3'), DNA (5'-D(P*TP*CP*GP*AP*TP*AP*AP*TP*AP*AP*AP*TP*AP*TP*TP*T)-3'), Hepatocyte nuclear factor 3-alpha, ... | 著者 | Choi, Y, Yoon, H.J, Lee, H.H. | 登録日 | 2021-10-15 | 公開日 | 2022-08-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations. Nucleic Acids Res., 50, 2022
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7FD4
| A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 1) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ... | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C. | 登録日 | 2021-07-16 | 公開日 | 2021-11-03 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Complete three-dimensional structures of the Lon protease translocating a protein substrate. Sci Adv, 7, 2021
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7FD5
| A complete three-dimensional structure of the Lon protease translocating a protein substrate (conformation 2) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Alpha-S1-casein, Lon protease, ... | 著者 | Li, S, Hsieh, K, Kuo, C, Lee, S, Pintilie, G, Zhang, K, Chang, C. | 登録日 | 2021-07-16 | 公開日 | 2021-11-03 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Complete three-dimensional structures of the Lon protease translocating a protein substrate. Sci Adv, 7, 2021
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2VNC
| Crystal structure of Glycogen Debranching enzyme TreX from Sulfolobus solfataricus | 分子名称: | GLYCOGEN OPERON PROTEIN GLGX | 著者 | Song, H.-N, Yoon, S.-M, Cha, H, Park, K.-T, Woo, E.-J. | 登録日 | 2008-02-04 | 公開日 | 2008-07-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Insight Into the Bifunctional Mechanism of the Glycogen-Debranching Enzyme Trex from the Archaeon Sulfolobus Solfataricus. J.Biol.Chem., 283, 2008
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6JTT
| MHETase in complex with BHET | 分子名称: | 4-(2-hydroxyethyloxycarbonyl)benzoic acid, CALCIUM ION, Mono(2-hydroxyethyl) terephthalate hydrolase, ... | 著者 | Sagong, H.-Y, Seo, H, Kim, K.-J. | 登録日 | 2019-04-12 | 公開日 | 2020-04-15 | 最終更新日 | 2020-10-28 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Decomposition of PET film by MHETase using Exo-PETase function Acs Catalysis, 10, 2020
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7RP6
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7RQ7
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7RSB
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7RNX
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7RO0
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7RP5
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6JTU
| Crystal structure of MHETase from Ideonella sakaiensis | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | 著者 | Sagong, H.-Y, Seo, H, Kim, K.-J. | 登録日 | 2019-04-12 | 公開日 | 2020-04-15 | 最終更新日 | 2020-10-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Decomposition of PET film by MHETase using Exo-PETase function Acs Catalysis, 10, 2020
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6TYQ
| Salmonella Typhi PltB Homopentamer with Neu-5NAc-9OAc-alpha-2-6-Gal-beta-1-4-GlcNAc Glycans | 分子名称: | 9-O-acetyl-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Pertussis-like toxin subunit B | 著者 | Nguyen, T, Milano, S.K, Yang, Y.A, Song, J. | 登録日 | 2019-08-09 | 公開日 | 2020-02-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication. Plos Pathog., 16, 2020
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6TYN
| Salmonella Typhi PltB Homopentamer with Neu-5NAc-9OAc-alpha-2-3-Gal-beta-1-4-GlcNAc Glycans | 分子名称: | 9-O-acetyl-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Pertussis like toxin subunit B | 著者 | Nguyen, T, Milano, S.K, Yang, Y.A, Song, J. | 登録日 | 2019-08-09 | 公開日 | 2020-02-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication. Plos Pathog., 16, 2020
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5VFC
| WDR5 bound to inhibitor MM-589 | 分子名称: | 1,2-ETHANEDIOL, N-{(3R,6S,9S,12R)-6-ethyl-12-methyl-9-[3-(N'-methylcarbamimidamido)propyl]-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetraazacyclotetradecan-12-yl}-2-methylpropanamide, SULFATE ION, ... | 著者 | Stuckey, J.A. | 登録日 | 2017-04-07 | 公開日 | 2017-06-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)-Mixed Lineage Leukemia (MLL) Protein-Protein Interaction. J. Med. Chem., 60, 2017
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5I9J
| Structure of the cholesterol and lutein-binding domain of human STARD3 at 1.74A | 分子名称: | 1,2-ETHANEDIOL, L(+)-TARTARIC ACID, SULFATE ION, ... | 著者 | Horvath, M.P, Bernstein, P.S, Li, B, George, E.W, Tran, Q.T. | 登録日 | 2016-02-20 | 公開日 | 2016-03-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Structure of the lutein-binding domain of human StARD3 at 1.74 angstrom resolution and model of a complex with lutein. Acta Crystallogr.,Sect.F, 72, 2016
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