4XP7
 
 | | Crystal structure of Human tRNA dihydrouridine synthase 2 | | 分子名称: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, tRNA-dihydrouridine(20) synthase [NAD(P)+]-like | | 著者 | Whelan, F, Jenkins, H.T, Griffiths, S, Byrne, R.T, Dodson, E.J, Antson, A.A. | | 登録日 | 2015-01-16 | | 公開日 | 2015-01-28 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | From bacterial to human dihydrouridine synthase: automated structure determination.
Acta Crystallogr.,Sect.D, 71, 2015
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4YJM
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4YKA
 | | The structure of Agrobacterium tumefaciens ClpS2 in complex with L-tyrosinamide | | 分子名称: | ATP-dependent Clp protease adapter protein ClpS 2, L-TYROSINAMIDE, SULFATE ION | | 著者 | Stein, B, Grant, R.A, Sauer, R.T, Baker, T.A. | | 登録日 | 2015-03-04 | | 公開日 | 2016-01-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | | 主引用文献 | Structural Basis of an N-Degron Adaptor with More Stringent Specificity.
Structure, 24, 2016
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4Z2B
 | | The structure of human PDE12 residues 161-609 in complex with GSK3036342A | | 分子名称: | 1,2-ETHANEDIOL, 2',5'-phosphodiesterase 12, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | Nolte, R.T, Wisely, B, Wang, L, Wood, E.R. | | 登録日 | 2015-03-29 | | 公開日 | 2015-06-17 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors.
J.Biol.Chem., 290, 2015
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4Z0V
 | | The structure of human PDE12 residues 161-609 | | 分子名称: | 2',5'-phosphodiesterase 12, GLYCEROL, MAGNESIUM ION | | 著者 | Nolte, R.T, Wisely, B, Wang, L, Wood, E.R. | | 登録日 | 2015-03-26 | | 公開日 | 2015-06-17 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors.
J.Biol.Chem., 290, 2015
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4YCO
 | | E. coli dihydrouridine synthase C (DusC) in complex with tRNAPhe | | 分子名称: | FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, MANGANESE (II) ION, ... | | 著者 | Byrne, R.T, Jenkins, H.T, Peters, D.T, Whelan, F, Stowell, J, Aziz, N, Kasatsky, P, Rodnina, M.V, Koonin, E.V, Konevega, A.L, Antson, A.A. | | 登録日 | 2015-02-20 | | 公開日 | 2015-04-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4WW1
 | | Crystal structure of human TCR Alpha Chain-TRAV21-TRAJ8 and Beta Chain-TRBV7-8 | | 分子名称: | TCR Alpha Chain-TRAV21-TRAJ8, TCR Beta Chain-TRBV7-8 | | 著者 | Le Nours, J, Praveena, T, Pellicci, D.G, Lim, R.T, Besra, G, Howell, A.R, Godfrey, D.I, Rossjohn, J, Uldrich, A.P. | | 登録日 | 2014-11-10 | | 公開日 | 2016-02-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.
Nat Commun, 7, 2016
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4WW2
 | | Crystal structure of human TCR Alpha Chain-TRAV21-TRAJ8, Beta Chain-TRBV7-8, Antigen-presenting glycoprotein CD1d, and Beta-2-microglobulin | | 分子名称: | (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ... | | 著者 | Le Nours, J, Praveena, T, Pellicci, D, Gherardin, N.A, Lim, R.T, Besra, G, Keshipeddy, S, Richardson, S.K, Howell, A.R, Gras, S, Godfrey, D.I, Rossjohn, J, Uldrich, A.P. | | 登録日 | 2014-11-10 | | 公開日 | 2016-02-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.
Nat Commun, 7, 2016
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4WWK
 | | Crystal structure of human TCR Alpha Chain-TRAV12-3, Beta Chain-TRBV6-5, Antigen-presenting molecule CD1d, and Beta-2-microglobulin | | 分子名称: | (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ... | | 著者 | Le Nours, J, Praveena, T, Pellicci, D.G, Gherardin, N.A, Lim, R.T, Besra, G, Keshipeddy, A, Richardson, S.K, Howell, A.R, Gras, S, Godfrey, D.I, Rossjohn, J, Uldrich, A.P. | | 登録日 | 2014-11-11 | | 公開日 | 2016-02-03 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.
Nat Commun, 7, 2016
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4YCP
 | | E. coli dihydrouridine synthase C (DusC) in complex with tRNATrp | | 分子名称: | FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Byrne, R.T, Jenkins, H.T, Peters, D.T, Whelan, F, Stowell, J, Aziz, N, Kasatsky, P, Rodnina, M.V, Koonin, E.V, Konevega, A.L, Antson, A.A. | | 登録日 | 2015-02-20 | | 公開日 | 2015-04-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4YJX
 | | The structure of Agrobacterium tumefaciens ClpS2 bound to L-phenylalaninamide | | 分子名称: | ATP-dependent Clp protease adapter protein ClpS 2, PHENYLALANINE AMIDE, SULFATE ION | | 著者 | Stein, B, Grant, R.A, Sauer, R.T, Baker, T.A. | | 登録日 | 2015-03-03 | | 公開日 | 2016-01-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.547 Å) | | 主引用文献 | Structural Basis of an N-Degron Adaptor with More Stringent Specificity.
Structure, 24, 2016
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6LAA
 | | Crystal structure of full-length CYP116B46 from Tepidiphilus thermophilus | | 分子名称: | 1,2-ETHANEDIOL, CARBONATE ION, Cytochrome P450, ... | | 著者 | Zhang, L.L, Ko, T.P, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2019-11-12 | | 公開日 | 2020-06-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Structural insight into the electron transfer pathway of a self-sufficient P450 monooxygenase.
Nat Commun, 11, 2020
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6KQX
 | | Crystal structure of Yijc from B. subtilis in complex with UDP | | 分子名称: | URIDINE-5'-DIPHOSPHATE, Uncharacterized UDP-glucosyltransferase YjiC | | 著者 | Hu, Y.M, Dai, L.H, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2019-08-20 | | 公開日 | 2020-09-30 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Structural dissection of unnatural ginsenoside-biosynthetic UDP-glycosyltransferase Bs-YjiC from Bacillus subtilis for substrate promiscuity.
Biochem.Biophys.Res.Commun., 534, 2021
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6KQW
 | | Crystal structure of Yijc from B. subtilis | | 分子名称: | CITRIC ACID, Uncharacterized UDP-glucosyltransferase YjiC | | 著者 | Hu, Y.M, Dai, L.H, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2019-08-20 | | 公開日 | 2020-09-30 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Structural dissection of unnatural ginsenoside-biosynthetic UDP-glycosyltransferase Bs-YjiC from Bacillus subtilis for substrate promiscuity.
Biochem.Biophys.Res.Commun., 534, 2021
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6LDL
 | | Crystal structure of CYP116B46-N(20-445) from Tepidiphilus thermophilus in complex with HEME | | 分子名称: | BICINE, Cytochrome P450, GLYCEROL, ... | | 著者 | Zhang, L.L, Xie, Z.Z, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2019-11-21 | | 公開日 | 2020-10-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Structural insight into the electron transfer pathway of a self-sufficient P450 monooxygenase.
Nat Commun, 11, 2020
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6LNH
 | | Crystal structure of IDO from Bacillus thuringiensis | | 分子名称: | FE (III) ION, L-isoleucine-4-hydroxylase, MERCURY (II) ION | | 著者 | Feng, Y, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2019-12-30 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Crystal structure of IDO from Bacillus thuringiensis
to be published
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6NCJ
 | | Structure of HIV-1 Integrase with potent 5,6,7,8-Tetrahydro-1,6-naphthyridine Derivatives Allosteric Site Inhibitors | | 分子名称: | (2~{S})-2-[4-(8-fluoranyl-5-methyl-3,4-dihydro-2~{H}-chromen-6-yl)-2-methyl-6-[[(1~{S},2~{R})-2-phenylcyclopropyl]methyl]-7,8-dihydro-5~{H}-1,6-naphthyridin-3-yl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid, 1,2-ETHANEDIOL, Integrase, ... | | 著者 | Nolte, R.T. | | 登録日 | 2018-12-11 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | 5,6,7,8-Tetrahydro-1,6-naphthyridine Derivatives as Potent HIV-1-Integrase-Allosteric-Site Inhibitors.
J. Med. Chem., 62, 2019
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4PER
 | | Structure of Gallus gallus ribonuclease inhibitor complexed with Gallus gallus ribonuclease I | | 分子名称: | Angiogenin, Ribonuclease Inhibitor | | 著者 | Bianchetti, C.M, Lomax, J.E, Raines, R.T, Fox, B.G. | | 登録日 | 2014-04-24 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Functional evolution of ribonuclease inhibitor: insights from birds and reptiles.
J.Mol.Biol., 426, 2014
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4Q2Z
 | | Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE356, from a non-human primate | | 分子名称: | Heavy chain of Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, Light chain of Fab fragment of HIV vaccine-elicited CD4bs-directed antibody | | 著者 | Navis, M, Tran, K, Bale, S, Phad, G, Guenaga, J, Wilson, R, Soldemo, M, McKee, K, Sundling, C, Mascola, J, Li, Y, Wyatt, R.T, Hedestam, G.B.K. | | 登録日 | 2014-04-10 | | 公開日 | 2014-09-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | HIV-1 Receptor Binding Site-Directed Antibodies Using a VH1-2 Gene Segment Orthologue Are Activated by Env Trimer Immunization.
Plos Pathog., 10, 2014
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4R0D
 | | Crystal structure of a eukaryotic group II intron lariat | | 分子名称: | GROUP IIB INTRON LARIAT, IRIDIUM HEXAMMINE ION, LIGATED EXONS, ... | | 著者 | Robart, A.R, Chan, R.T, Peters, J.K, Rajashankar, K.R, Toor, N. | | 登録日 | 2014-07-30 | | 公開日 | 2014-10-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.676 Å) | | 主引用文献 | Crystal structure of a eukaryotic group II intron lariat.
Nature, 514, 2014
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4PEQ
 | | Structure of bovine ribonuclease inhibitor complexed with bovine ribonuclease I | | 分子名称: | Ribonuclease pancreatic, Ribonuclease/angiogenin inhibitor 1 | | 著者 | Bianchetti, C.M, Lomax, J.E, Raines, R.T, Fox, B.G. | | 登録日 | 2014-04-24 | | 公開日 | 2014-06-25 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.211 Å) | | 主引用文献 | Functional evolution of ribonuclease inhibitor: insights from birds and reptiles.
J.Mol.Biol., 426, 2014
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4RSD
 | | STRUCTURE OF THE D121A VARIANT OF RIBONUCLEASE A | | 分子名称: | ACETATE ION, CHLORIDE ION, RIBONUCLEASE A | | 著者 | Schultz, L.W, Quirk, D.J, Raines, R.T. | | 登録日 | 1998-02-05 | | 公開日 | 1998-07-15 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | His...Asp catalytic dyad of ribonuclease A: structure and function of the wild-type, D121N, and D121A enzymes.
Biochemistry, 37, 1998
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4RSK
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4RQZ
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4RR0
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