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1AXV
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BU of 1axv by Molmil
SOLUTION NMR STRUCTURE OF THE [BP]DA ADDUCT OPPOSITE DT IN A DNA DUPLEX, 6 STRUCTURES
分子名称: 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, DNA DUPLEX D(CTCTC-[BP]A-CTTCC)D(GGAAGTGAGAG)
著者Mao, B, Gu, Z, Gorin, A.A, Chen, J, Hingerty, B.E, Amid, S, Broyde, S, Geacintov, N.E, Patel, D.J.
登録日1997-10-21
公開日1998-07-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the (+)-cis-anti-benzo[a]pyrene-dA ([BP]dA) adduct opposite dT in a DNA duplex.
Biochemistry, 38, 1999
2KGG
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BU of 2kgg by Molmil
Solution Structure of JARID1A C-terminal PHD finger
分子名称: Histone demethylase JARID1A, ZINC ION
著者Song, J, Wang, Z, Patel, D.J.
登録日2009-03-11
公開日2009-05-05
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature, 459, 2009
2H6N
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BU of 2h6n by Molmil
Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
分子名称: Histone H3 K4-Me2 9-residue peptide, WD-repeat protein 5
著者Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-05-31
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
2KF7
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BU of 2kf7 by Molmil
Structure of a two-G-tetrad basket-type intramolecular G-quadruplex formed by human telomeric repeats in K+ solution (with G7-to-BRG substitution)
分子名称: HUMAN TELOMERE DNA
著者Lim, K.W, Amrane, S, Bouaziz, S, Xu, W, Mu, Y, Patel, D.J, Luu, K.N, Phan, A.T.
登録日2009-02-12
公開日2009-03-24
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers
J.Am.Chem.Soc., 131, 2009
2H68
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Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
分子名称: WD-repeat protein 5
著者Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-05-30
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
2H6K
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BU of 2h6k by Molmil
Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex
分子名称: Histone H3 K4-Me 9-residue peptide, WD-repeat protein 5
著者Ruthenburg, A.J, Wang, W.-K, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L.
登録日2006-05-31
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Histone H3 recognition and presentation by the WDR5 module of the MLL1 complex.
Nat.Struct.Mol.Biol., 13, 2006
1A8W
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BU of 1a8w by Molmil
A K+ CATION-INDUCED CONFORMATIONAL SWITCH WITHIN A LOOP SPANNING SEGMENT OF A DNA QUADRUPLEX CONTAINING G-G-G-C REPEATS, NMR, 8 STRUCTURES
分子名称: DNA QUADRUPLEX CONTAINING GGGG TETRADS AND GC WATSON-CRICK BASE PAIRS
著者Bouaziz, S, Kettani, A, Patel, D.J.
登録日1998-03-28
公開日1998-10-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A K cation-induced conformational switch within a loop spanning segment of a DNA quadruplex containing G-G-G-C repeats.
J.Mol.Biol., 282, 1998
1B3P
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5'-D(*GP*GP*AP*GP*GP*AP*T)-3'
分子名称: DNA (5'-D(*GP*GP*AP*GP*GP*AP*T)-3')
著者Kettani, A, Bouaziz, S, Skripkin, E, Majumdar, A, Wang, W, Jones, R.A, Patel, D.J.
登録日1998-12-14
公開日1999-08-31
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Interlocked mismatch-aligned arrowhead DNA motifs.
Structure Fold.Des., 7, 1999
2KF8
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BU of 2kf8 by Molmil
Structure of a two-G-tetrad basket-type intramolecular G-quadruplex formed by human telomeric repeats in K+ solution
分子名称: HUMAN TELOMERE DNA
著者Lim, K.W, Amrane, S, Bouaziz, S, Xu, W, Mu, Y, Patel, D.J, Luu, K.N, Phan, A.T.
登録日2009-02-12
公開日2009-03-24
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers
J.Am.Chem.Soc., 131, 2009
2KGI
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BU of 2kgi by Molmil
Solution structure of JARID1A C-terminal PHD finger in complex with H3(1-9)K4me3
分子名称: H3(1-9)K4me3, Histone demethylase JARID1A, ZINC ION
著者Song, J, Wang, Z, Patel, D.J.
登録日2009-03-12
公開日2009-05-05
最終更新日2020-02-26
実験手法SOLUTION NMR
主引用文献Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature, 459, 2009
2KYO
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BU of 2kyo by Molmil
Dimeric human ckit-2 proto-oncogene promoter quadruplex DNA NMR, 10 structures
分子名称: 5'-D(*CP*GP*GP*GP*CP*GP*GP*GP*CP*GP*CP*GP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3'
著者Kuryavyi, V, Phan, A.T, Patel, D.J.
登録日2010-06-05
公開日2010-06-30
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter.
Nucleic Acids Res., 38, 2010
1B5K
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BU of 1b5k by Molmil
3,N4-ETHENO-2'-DEOXYCYTIDINE OPPOSITE THYMIDINE IN AN 11-MER DUPLEX, SOLUTION STRUCTURE FROM NMR AND MOLECULAR DYNAMICS
分子名称: DNA (5'-D(*CP*GP*TP*AP*CP*EDCP*CP*AP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*TP*GP*TP*GP*TP*AP*CP*G)-3')
著者Cullinan, D, Korobka, A, Grollman, A.P, Patel, D.J, Eisenberg, M, De Santos, C.L.
登録日1999-01-07
公開日1999-01-13
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献NMR solution structure of an oligodeoxynucleotide duplex containing the exocyclic lesion 3,N4-etheno-2'-deoxycytidine opposite thymidine: comparison with the duplex containing deoxyadenosine opposite the adduct.
Biochemistry, 35, 1996
2KPR
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BU of 2kpr by Molmil
Monomeric intronic human chl1 gene quadruplex DNA NMR, 17 structures
分子名称: 5'-D(*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*GP*GP*GP*TP*GP*GP*GP*T)-3'
著者Kuryavyi, V, Patel, D.J.
登録日2009-10-19
公開日2010-03-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of a Unique G-Quadruplex Scaffold Adopted by a Guanosine-Rich Human Intronic Sequence.
Structure, 18, 2010
1EEG
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BU of 1eeg by Molmil
A(GGGG)A HEXAD PAIRING ALIGMENT FOR THE D(G-G-A-G-G-A-G) SEQUENCE
分子名称: DNA (5'-D(*GP*GP*AP*GP*GP*A)-3')
著者Kettani, A, Gorin, A, Majumdar, A, Hermann, T, Skripkin, E, Zhao, H, Jones, R, Patel, D.J.
登録日2000-01-31
公開日2000-04-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A dimeric DNA interface stabilized by stacked A.(G.G.G.G).A hexads and coordinated monovalent cations.
J.Mol.Biol., 297, 2000
2KYP
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BU of 2kyp by Molmil
Monomeric Human CKIT-2 proto-oncogene promoter quadruplex DNA NMR, 12 structures
分子名称: 5'-D(*CP*GP*GP*GP*CP*GP*GP*GP*CP*GP*CP*TP*AP*GP*GP*GP*AP*GP*GP*GP*T)-3'
著者Kuryavyi, V, Phan, A.T, Patel, D.J.
登録日2010-06-06
公開日2010-06-30
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter.
Nucleic Acids Res., 38, 2010
1EXY
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BU of 1exy by Molmil
SOLUTION STRUCTURE OF HTLV-1 PEPTIDE BOUND TO ITS RNA APTAMER TARGET
分子名称: HTLV-1 REX PEPTIDE, RNA APTAMER, 33-MER
著者Jiang, F, Gorin, A, Hu, W, Majumdar, A, Baskerville, S, Xu, W, Ellington, A, Patel, D.J.
登録日2000-05-05
公開日2000-05-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Anchoring an extended HTLV-1 Rex peptide within an RNA major groove containing junctional base triples.
Structure Fold.Des., 7, 1999
5U34
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BU of 5u34 by Molmil
Crystal structure of AacC2c1-sgRNA binary complex
分子名称: CRISPR-associated endonuclease C2c1, sgRNA
著者Yang, H, Gao, P, Rajashankar, K.R, Patel, D.J.
登録日2016-12-01
公開日2017-01-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.255 Å)
主引用文献PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease.
Cell, 167, 2016
5U30
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Crystal structure of AacC2c1-sgRNA-extended target DNA ternary complex
分子名称: CRISPR-associated endonuclease C2c1, Non-target DNA strand, SULFATE ION, ...
著者Yang, H, Gao, P, Rajashankar, K.R, Patel, D.J.
登録日2016-12-01
公開日2017-01-25
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease.
Cell, 167, 2016
5U33
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BU of 5u33 by Molmil
Crystal structure of AacC2c1-sgRNA-extended non-target DNA ternary complex
分子名称: CRISPR-associated endonuclease C2c1, Non-target DNA strand, SULFATE ION, ...
著者Yang, H, Gao, P, Rajashankar, K.R, Patel, D.J.
登録日2016-12-01
公開日2017-01-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.75 Å)
主引用文献PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease.
Cell, 167, 2016
5U31
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Crystal structure of AacC2c1-sgRNA-8mer substrate DNA ternary complex
分子名称: CRISPR-associated endonuclease C2c1, Non-target DNA strand, SULFATE ION, ...
著者Yang, H, Gao, P, Rajashankar, K.R, Patel, D.J.
登録日2016-12-01
公開日2017-01-25
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease.
Cell, 167, 2016
5VW1
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BU of 5vw1 by Molmil
Crystal structure of SpyCas9-sgRNA-AcrIIA4 ternary complex
分子名称: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9/Csn1, DI(HYDROXYETHYL)ETHER, ...
著者Yang, H, Patel, D.J.
登録日2017-05-21
公開日2017-06-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.598 Å)
主引用文献Inhibition Mechanism of an Anti-CRISPR Suppressor AcrIIA4 Targeting SpyCas9.
Mol. Cell, 67, 2017
3PT6
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BU of 3pt6 by Molmil
Crystal structure of mouse DNMT1(650-1602) in complex with DNA
分子名称: DNA (5'-D(*CP*CP*TP*GP*CP*GP*GP*AP*GP*GP*CP*TP*CP*AP*CP*GP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*CP*GP*TP*GP*AP*GP*CP*CP*TP*CP*CP*GP*CP*AP*GP*G)-3'), DNA (cytosine-5)-methyltransferase 1, ...
著者Song, J, Patel, D.J.
登録日2010-12-02
公開日2010-12-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.
Science, 331, 2011
3Q0B
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Crystal structure of SUVH5 SRA- fully methylated CG DNA complex in space group P42212
分子名称: DNA (5'-D(*AP*CP*TP*AP*(5CM)P*GP*TP*AP*GP*T)-3'), Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5
著者Eerappa, R, Simanshu, D.K, Patel, D.J.
登録日2010-12-15
公開日2011-02-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
Genes Dev., 25, 2011
3Q0F
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Crystal structure of SUVH5 SRA- methylated CHH DNA complex
分子名称: DNA (5'-D(*CP*TP*GP*AP*GP*GP*AP*GP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*CP*TP*(5CM)P*CP*TP*CP*AP*G)-3'), Histone-lysine N-methyltransferase, ...
著者Eerappa, R, Simanshu, D.K, Patel, D.J.
登録日2010-12-15
公開日2011-02-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo.
Genes Dev., 25, 2011
3PT9
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Crystal structure of mouse DNMT1(731-1602) in the free state
分子名称: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
著者Song, J, Patel, D.J.
登録日2010-12-02
公開日2010-12-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.
Science, 331, 2011

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