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4AX8
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BU of 4ax8 by Molmil
Medium resolution structure of the bifunctional kinase- methyltransferase WbdD
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, S-ADENOSYLMETHIONINE, ...
著者Hagelueken, G, Huang, H, Naismith, J.H.
登録日2012-06-11
公開日2012-10-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystallization, Dehydration and Experimental Phasing of Wbdd, a Bifunctional Kinase and Methyltransferase from Escherichia Coli O9A.
Acta Crystallogr.,Sect.D, 68, 2012
4AZT
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BU of 4azt by Molmil
Co-crystal structure of WbdD and kinase inhibitor LY294002.
分子名称: 2-MORPHOLIN-4-YL-7-PHENYL-4H-CHROMEN-4-ONE, CHLORIDE ION, METHYLTRANSFERASE WBDD, ...
著者Hagelueken, G, Huang, H, Naismith, J.H.
登録日2012-06-26
公開日2012-09-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Structure of Wbdd; a Bifunctional Kinase and Methyltransferase that Regulates the Chain Length of the O Antigen in Escherichia Coli O9A.
Mol.Microbiol., 86, 2012
4AZS
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High resolution (2.2 A) crystal structure of WbdD.
分子名称: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, METHYLTRANSFERASE WBDD, ...
著者Hagelueken, G, Huang, H, Naismith, J.H.
登録日2012-06-26
公開日2012-09-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of Wbdd; a Bifunctional Kinase and Methyltransferase that Regulates the Chain Length of the O Antigen in Escherichia Coli O9A.
Mol.Microbiol., 86, 2012
4CCV
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BU of 4ccv by Molmil
Crystal structure of histidine-rich glycoprotein N2 domain reveals redox activity at an interdomain disulfide bridge: Implications for the regulation of angiogenesis
分子名称: GLUTATHIONE, GLYCEROL, HISTIDINE-RICH GLYCOPROTEIN, ...
著者McMahon, S.A, Kassaar, O, Stewart, A.J, Naismith, J.H.
登録日2013-10-29
公開日2014-02-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal Structure of Histidine-Rich Glycoprotein N2 Domain Reveals Redox Activity at an Interdomain Disulfide Bridge: Implications for Angiogenic Regulation.
Blood, 123, 2014
4BS9
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Structure of the heterocyclase TruD
分子名称: TRUD, ZINC ION
著者Koehnke, J, Bent, A.F, Zollman, D, Smith, K, Houssen, W.E, Zhu, X, Mann, G, Lebl, T, Scharff, R, Shirran, S, Botting, C.H, Jaspars, M, Schwarz-Linek, U, Naismith, J.H.
登録日2013-06-09
公開日2013-11-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Cyanobactin Heterocyclase Enzyme: A Processive Adenylase that Operates with a Defined Order of Reaction.
Angew.Chem.Int.Ed.Engl., 52, 2013
4BMK
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BU of 4bmk by Molmil
Serine Palmitoyltransferase K265A from S. paucimobilis with bound PLP- Myriocin Aldimine
分子名称: Decarboxylated Myriocin, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ...
著者Wadsworth, J.M, Clarke, D.J, McMahon, S.A, Beattie, A.E, Lowther, J, Dunn, T.M, Naismith, J.H, Campopiano, D.J.
登録日2013-05-09
公開日2013-09-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献The Chemical Basis of Serine Palmitoyltransferase Inhibition by Myriocin.
J.Am.Chem.Soc., 135, 2013
4BQQ
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BU of 4bqq by Molmil
Protein crystal structure of the N-terminal and recombinase domains of the Streptomyces temperate phage serine recombinase, fC31 integrase.
分子名称: INTEGRASE
著者McMahon, S.A, McEwan, A.R, Smith, M.C.M, Naismith, J.H.
登録日2013-05-31
公開日2013-06-12
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Protein Crystal Structure of the N-Terminal and Recombinase Domains of the Streptomyces Temperate Phage Serine Recombinase, Fc31 Integrase.
To be Published
4CQJ
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Fluorinase substrate flexibility enables last step aqueous and ambient 18F fluorination of a RGD peptide for positron emission tomography
分子名称: 5'-FLUORO-5'-DEOXY-ADENOSINE SYNTHASE, 5'-deoxy-2-ethynyl-5'-fluoroadenosine
著者McMahon, S.A, Thompson, S, O'Hagan, D, Naismith, J.H.
登録日2014-02-17
公開日2014-05-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structure of a Bacterial Fluorinating Enzyme with
To be Published
4CL6
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Crystal Structure of 3-hydroxydecanoyl-Acyl Carrier Protein Dehydratase (FabA) from Pseudomonas aeruginosa in complex with N-(4- Chlorobenzyl)-3-(2-furyl)-1H-1,2,4-triazol-5-amine
分子名称: 3-HYDROXYDECANOYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE, N-(4-chlorobenzyl)-5-(furan-2-yl)-1H-1,2,4-triazol-3-amine
著者Moynie, L, McMahon, S.A, Duthie, F.G, Naismith, J.H.
登録日2014-01-13
公開日2015-01-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献A Substrate Mimic Allows High Throughput Assay of the Faba Protein and Consequently the Identification of a Novel Inhibitor of Pseudomonas Aeruginosa Faba.
J.Mol.Biol., 428, 2016
4FQ9
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Crystal Structure of 3-hydroxydecanoyl-Acyl Carrier Protein Dehydratase (FabA) from Pseudomonas aeruginosa
分子名称: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, GLYCEROL, PHOSPHATE ION
著者Moynie, L, Mcmahon, S.A, Duthie, F.G, Naismith, J.H.
登録日2012-06-25
公開日2013-03-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural insights into the mechanism and inhibition of the beta-hydroxydecanoyl-acyl carrier protein dehydratase from Pseudomonas aeruginosa
J.Mol.Biol., 425, 2013
2WES
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BU of 2wes by Molmil
Crystal structures of mutant E46Q of tryptophan 5-halogenase (PyrH)
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, TRYPTOPHAN 5-HALOGENASE
著者Zhu, X, Naismith, J.H.
登録日2009-04-01
公開日2009-04-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Insights in the Regioselectivity in the Enzymatic Chlorination of Tryptophan.
J.Mol.Biol., 391, 2009
2W8U
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BU of 2w8u by Molmil
SPT with PLP, N100Y
分子名称: PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE
著者Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H.
登録日2009-01-19
公開日2009-01-27
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
2WEU
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BU of 2weu by Molmil
Crystal structure of tryptophan 5-halogenase (PyrH) complex with substrate tryptophan
分子名称: TRYPTOPHAN, TRYPTOPHAN 5-HALOGENASE
著者Leang, K, Zhu, X, Naismith, J.H.
登録日2009-04-01
公開日2009-04-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Insights in the Regioselectivity in the Enzymatic Chlorination of Tryptophan.
J.Mol.Biol., 391, 2009
2W8H
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BU of 2w8h by Molmil
Crystal structure of spin labeled Wza24-345.
分子名称: CHLORIDE ION, PUTATIVE OUTER MEMBRANE LIPOPROTEIN WZA, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
著者Hagelueken, G, Ingledew, W.J, Huang, H, Petrovic-Stojanovska, B, Whitfield, C, ElMkami, H, Schiemann, O, Naismith, J.H.
登録日2009-01-16
公開日2009-02-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Peldor Distance Fingerprinting of the Octameric Outer-Membrane Protein Wza from Escherichia Coli.
Angew.Chem.Int.Ed.Engl., 48, 2009
2W0M
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BU of 2w0m by Molmil
Crystal Structure of sso2452 from Sulfolobus solfataricus P2
分子名称: PYROPHOSPHATE 2-, SSO2452, ZINC ION
著者McRobbie, A, Carter, L, Johnson, K.A, Kerou, M, Liu, H, Mcmahon, S, Oke, M, Naismith, J.H, White, M.F.
登録日2008-08-19
公開日2009-05-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Functional Characterisation of a Conserved Archaeal Rada Paralog with Antirecombinase Activity.
J.Mol.Biol., 389, 2009
2W8W
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BU of 2w8w by Molmil
N100Y SPT with PLP-ser
分子名称: SERINE PALMITOYLTRANSFERASE, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE
著者Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H.
登録日2009-01-19
公開日2009-01-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
2VW8
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BU of 2vw8 by Molmil
Crystal Structure of Quinolone signal response protein pqsE from Pseudomonas aeruginosa
分子名称: 1,2-ETHANEDIOL, CACODYLATE ION, FE (II) ION, ...
著者Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, Oke, M, Naismith, J.H, White, M.F.
登録日2008-06-17
公開日2010-07-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
2X5D
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BU of 2x5d by Molmil
Crystal Structure of a probable aminotransferase from Pseudomonas aeruginosa
分子名称: PROBABLE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
著者Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, White, M.F, Naismith, J.H.
登録日2010-02-08
公開日2010-07-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genom., 11, 2010
2WJD
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Crystal structure of the tyrosine phosphatase Cps4B from Steptococcus pneumoniae TIGR4.
分子名称: MANGANESE (II) ION, SAMARIUM (III) ION, SULFATE ION, ...
著者Hagelueken, G, Huang, H, Naismith, J.H.
登録日2009-05-25
公開日2009-07-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.799 Å)
主引用文献Crystal Structures of Wzb of Escherichia Coli and Cpsb of Streptococcus Pneumoniae, Representatives of Two Families of Tyrosine Phosphatases that Regulate Capsule Assembly.
J.Mol.Biol., 392, 2009
2X6T
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AGME bound to ADP-B-mannose
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADP-L-GLYCERO-D-MANNO-HEPTOSE-6-EPIMERASE, CHLORIDE ION, ...
著者Kowatz, T, Morrison, J.P, Tanner, M.E, Naismith, J.H.
登録日2010-02-21
公開日2010-03-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献The Crystal Structure of the Y140F Mutant of Adp-L-Glycero-D-Manno-Heptose 6-Epimerase Bound to Adp-Beta-D-Mannose Suggests a One Base Mechanism.
Protein Sci., 19, 2010
2X0F
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Structure of WsaF in complex with dTDP-beta-L-Rha
分子名称: 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, GLYCEROL, WSAF
著者Steiner, K, Hagelueken, G, Naismith, J.H.
登録日2009-12-08
公開日2010-02-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural Basis of Substrate Binding in Wsaf, a Rhamnosyltransferase from Geobacillus Stearothermophilus.
J.Mol.Biol., 397, 2010
2WJF
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Crystal structure of the tyrosine phosphatase Cps4B from Steptococcus pneumoniae TIGR4 in complex with phosphate.
分子名称: MANGANESE (II) ION, PHOSPHATE ION, TYROSINE-PROTEIN PHOSPHATASE CPSB
著者Hagelueken, G, Huang, H, Naismith, J.H.
登録日2009-05-25
公開日2009-07-14
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Crystal Structures of Wzb of Escherichia Coli and Cpsb of Streptococcus Pneumoniae, Representatives of Two Families of Tyrosine Phosphatases that Regulate Capsule Assembly.
J.Mol.Biol., 392, 2009
2X3N
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Crystal structure of pqsL, a probable FAD-dependent monooxygenase from Pseudomonas aeruginosa
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, PROBABLE FAD-DEPENDENT MONOOXYGENASE
著者Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, White, M.F, Naismith, J.H.
登録日2010-01-25
公開日2010-07-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
2X4H
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Crystal Structure of the hypothetical protein SSo2273 from Sulfolobus solfataricus
分子名称: HYPOTHETICAL PROTEIN SSO2273, ZINC ION
著者Oke, M, Carter, L.G, Johnson, K.A, Liu, H, Mcmahon, S.A, White, M.F, Naismith, J.H.
登録日2010-01-31
公開日2010-07-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Scottish Structural Proteomics Facility: Targets, Methods and Outputs.
J.Struct.Funct.Genomics, 11, 2010
2X3J
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CO-COMPLEX STRUCTURE OF ACHROMOBACTIN SYNTHETASE PROTEIN D (ACSD) WITH ATP AND N-CITRYL-ETHYLENEDIAMINE FROM PECTOBACTERIUM CHRYSANTHEMI
分子名称: (2S)-2-{2-[(2-AMINOETHYL)AMINO]-2-OXOETHYL}-2-HYDROXYBUTANEDIOIC ACID, ACSD, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Schmelz, S, Challis, G.L, Naismith, J.H.
登録日2010-01-25
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Acyl Acceptor Specificity in the Achromobactin Biosynthetic Enzyme Acsd.
J.Mol.Biol., 412, 2011

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