2G0C
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8DKC
| P. gingivalis RNA Polymerase | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Liu, B, Bu, F. | 登録日 | 2022-07-05 | 公開日 | 2023-06-21 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM Structure of Porphyromonas gingivalis RNA Polymerase. J.Mol.Biol., 436, 2024
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6J1O
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6J46
| LepI-SAH complex structure | 分子名称: | O-methyltransferase lepI, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Qiu, S, Wei, C. | 登録日 | 2019-01-08 | 公開日 | 2019-05-01 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.621 Å) | 主引用文献 | Deciphering the regulatory and catalytic mechanisms of an unusual SAM-dependent enzyme. Signal Transduct Target Ther, 4, 2019
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6J24
| Crystal structure of a SAM-dependent methyltransferase LepI in complex with its substrate | 分子名称: | (3~{S},4'~{R},4'~{a}~{S},6'~{R},8'~{a}~{S})-4',6'-dimethyl-5-phenyl-spiro[1~{H}-pyridine-3,5'-2,3,4,4~{a},6,8~{a}-hexahydro-1~{H}-naphthalene]-2,4-dione, O-methyltransferase, S-ADENOSYLMETHIONINE | 著者 | Qiu, S, Wei, C. | 登録日 | 2018-12-30 | 公開日 | 2019-05-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.244 Å) | 主引用文献 | Deciphering the regulatory and catalytic mechanisms of an unusual SAM-dependent enzyme. Signal Transduct Target Ther, 4, 2019
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2MT9
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2MTB
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6OCG
| Crystal structure of VASH1-SVBP complex bound with EpoY | 分子名称: | CHLORIDE ION, GLYCEROL, N-[(3R)-4-ethoxy-3-hydroxy-4-oxobutanoyl]-L-tyrosine, ... | 著者 | Li, F, Luo, X, Yu, H. | 登録日 | 2019-03-23 | 公開日 | 2019-06-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.833 Å) | 主引用文献 | Structural basis of tubulin detyrosination by vasohibins. Nat.Struct.Mol.Biol., 26, 2019
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5ZVV
| Structure of SeMet-phAimR | 分子名称: | AimR transcriptional regulator, GLYCEROL | 著者 | Cheng, W, Dou, C. | 登録日 | 2018-05-13 | 公開日 | 2018-09-05 | 最終更新日 | 2019-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and functional insights into the regulation of the lysis-lysogeny decision in viral communities. Nat Microbiol, 3, 2018
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5ZW6
| Structure of spAimR | 分子名称: | AimR transcriptional regulator, GLY-MET-PRO-ARG-GLY-ALA | 著者 | Cheng, W, Dou, C. | 登録日 | 2018-05-14 | 公開日 | 2018-09-05 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural and functional insights into the regulation of the lysis-lysogeny decision in viral communities. Nat Microbiol, 3, 2018
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5ZW5
| Structure of SeMet-spAimR | 分子名称: | AimR transcriptional regulator | 著者 | Cheng, W, Dou, C. | 登録日 | 2018-05-14 | 公開日 | 2018-08-29 | 最終更新日 | 2019-03-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and functional insights into the regulation of the lysis-lysogeny decision in viral communities. Nat Microbiol, 3, 2018
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5ZVW
| Structure of phAimR-Ligand | 分子名称: | AimR transcriptional regulator, SER-ALA-ILE-ARG-GLY-ALA | 著者 | Cheng, W, Dou, C. | 登録日 | 2018-05-13 | 公開日 | 2018-09-05 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.292 Å) | 主引用文献 | Structural and functional insights into the regulation of the lysis-lysogeny decision in viral communities. Nat Microbiol, 3, 2018
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5ZXL
| Structure of GldA from E.coli | 分子名称: | CHLORIDE ION, GLYCEROL, Glycerol dehydrogenase, ... | 著者 | Zhang, J, Lin, L. | 登録日 | 2018-05-21 | 公開日 | 2019-03-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | 主引用文献 | Structure of glycerol dehydrogenase (GldA) from Escherichia coli. Acta Crystallogr F Struct Biol Commun, 75, 2019
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2QU3
| BACE1 with Compound 2 | 分子名称: | Beta-secretase 1, N-[amino(imino)methyl]-2-[2-(2-chlorophenyl)-4-(4-propoxyphenyl)-3-thienyl]acetamide | 著者 | Chopra, R. | 登録日 | 2007-08-03 | 公開日 | 2008-08-05 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Thiophene substituted acylguanidines as BACE1 inhibitors. Bioorg.Med.Chem.Lett., 17, 2007
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1PEF
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2ZDZ
| X-ray structure of Bace-1 in complex with compound 3.b.10 | 分子名称: | Beta-secretase 1, N-carbamimidoyl-2-[2-(2-chlorophenyl)-5-[4-(4-ethanoylphenoxy)phenyl]pyrrol-1-yl]ethanamide | 著者 | Chopra, R, Olland, A. | 登録日 | 2007-12-04 | 公開日 | 2008-12-09 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets. Bioorg.Med.Chem.Lett., 18, 2008
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6O1S
| Structure of human plasma kallikrein protease domain with inhibitor | 分子名称: | 1,2-ETHANEDIOL, N-[(6-amino-2,4-dimethylpyridin-3-yl)methyl]-1-({4-[(1H-pyrazol-1-yl)methyl]phenyl}methyl)-1H-pyrazole-4-carboxamide, PHOSPHATE ION, ... | 著者 | Partridge, J.R, Choy, R.M. | 登録日 | 2019-02-21 | 公開日 | 2019-03-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structures of full-length plasma kallikrein bound to highly specific inhibitors describe a new mode of targeted inhibition. J.Struct.Biol., 206, 2019
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2ZE1
| X-ray structure of Bace-1 in complex with compound 6g | 分子名称: | 3-bromo-N-[4-[1-(2-carbamimidamido-2-oxo-ethyl)-5-phenyl-pyrrol-2-yl]phenyl]benzamide, Beta-secretase 1 | 著者 | Chopra, R, Olland, A. | 登録日 | 2007-12-05 | 公開日 | 2008-12-09 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets. Bioorg.Med.Chem.Lett., 18, 2008
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5J1A
| Antigen presenting molecule | 分子名称: | 3-[(8Z,11Z)-pentadeca-8,11-dien-1-yl]benzene-1,2-diol, Beta-2-microglobulin, T-cell surface glycoprotein CD1a | 著者 | Yongqing, T, Rossjohn, J, Le Nours, J, Marquez, E, Winau, F. | 登録日 | 2016-03-29 | 公開日 | 2016-08-03 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | CD1a on Langerhans cells controls inflammatory skin disease. Nat. Immunol., 17, 2016
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6CJ7
| Crystal structure of Manduca sexta Serine protease inhibitor (Serpin)-12 | 分子名称: | Serpin-12 | 著者 | Gulati, M, Hu, Y, Peng, S, Pathak, P.K, Wang, Y, Deng, J, Jiang, H. | 登録日 | 2018-02-26 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Manduca sexta serpin-12 controls the prophenoloxidase activation system in larval hemolymph. Insect Biochem. Mol. Biol., 99, 2018
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7Y9G
| Crystal structure of diterpene synthase VenA from Streptomyces venezuelae ATCC 15439 in complex with pyrophosphate | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | 著者 | Zhang, L.L, Xie, Z.Z, Huang, J.-W, Hu, Y.C, Liu, W.D, Yang, Y, Chen, C.-C, Guo, R.-T. | 登録日 | 2022-06-24 | 公開日 | 2023-06-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Molecular insights into the catalytic promiscuity of a bacterial diterpene synthase. Nat Commun, 14, 2023
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7Y9H
| Crystal structure of diterpene synthase VenA from Streptomyces venezuelae ATCC 15439 | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Diterpene synthase VenA, ... | 著者 | Zhang, L.L, Xie, Z.Z, Huang, J.-W, Hu, Y.C, Liu, W.D, Yang, Y, Chen, C.-C, Guo, R.-T. | 登録日 | 2022-06-24 | 公開日 | 2023-06-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Molecular insights into the catalytic promiscuity of a bacterial diterpene synthase. Nat Commun, 14, 2023
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6IJ1
| Crystal structure of a protein from Actinoplanes | 分子名称: | ACETATE ION, IMIDAZOLE, Prenylcyclase | 著者 | Yang, Z.Z, Zhang, L.L, Liu, W.D, Chen, C.C, Guo, R.T. | 登録日 | 2018-10-08 | 公開日 | 2019-09-11 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.521 Å) | 主引用文献 | Crystal structure of TchmY from Actinoplanes teichomyceticus. Acta Crystallogr.,Sect.F, 75, 2019
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7W5S
| A nonheme iron- and alpha-ketoglutarate- dependent halogenase that catalyzes nucleotide substrates | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FE (II) ION, ... | 著者 | Dai, L.H, Zhang, X, Hu, Y.M, Huang, J.W, Chen, C.C, Guo, R.T. | 登録日 | 2021-11-30 | 公開日 | 2022-04-13 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Structural and Functional Insights into a Nonheme Iron- and alpha-Ketoglutarate-Dependent Halogenase That Catalyzes Chlorination of Nucleotide Substrates. Appl.Environ.Microbiol., 88, 2022
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7W5T
| A nonheme iron- and alpha-ketoglutarate- dependent halogenase that catalyzes nucleotide substrates | 分子名称: | 2-OXOGLUTARIC ACID, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Dai, L.H, Zhang, X, Hu, Y.M, Huang, J.W, Chen, C.C, Guo, R.T. | 登録日 | 2021-11-30 | 公開日 | 2022-04-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Structural and Functional Insights into a Nonheme Iron- and alpha-Ketoglutarate-Dependent Halogenase That Catalyzes Chlorination of Nucleotide Substrates. Appl.Environ.Microbiol., 88, 2022
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