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7XMS
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BU of 7xms by Molmil
CryoEM structure of somatostatin receptor 4 (SSTR4) in complex with Gi1 and its endogeneous ligand SST-14
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
著者Wenli, Z, Shuo, H, Na, Q, Wenbo, Z, Mengjie, L, Dehua, Y, Ming-Wei, W, Wu, B, Zhao, Q.
登録日2022-04-26
公開日2022-08-03
最終更新日2022-08-17
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural insights into ligand recognition and selectivity of somatostatin receptors.
Cell Res., 32, 2022
7VAA
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BU of 7vaa by Molmil
Crystal structure of MiCGT(W93V/V124F/ F191A/R282H) in complex with UDPs
分子名称: UDP-glycosyltransferase 13, URIDINE-5'-DIPHOSPHATE
著者Zhong, L, Zhang, Z.M.
登録日2021-08-27
公開日2022-07-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.10002756 Å)
主引用文献Directed Evolution of a Plant Glycosyltransferase for Chemo- and Regioselective Glycosylation of Pharmaceutically Significant Flavonoids
Acs Catalysis, 11, 2021
7VA8
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BU of 7va8 by Molmil
Crystal structure of MiCGT
分子名称: UDP-glycosyltransferase 13, URIDINE-5'-DIPHOSPHATE-GLUCOSE
著者Zhong, L, Zhang, Z.M.
登録日2021-08-27
公開日2022-07-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.85003233 Å)
主引用文献Directed Evolution of a Plant Glycosyltransferase for Chemo- and Regioselective Glycosylation of Pharmaceutically Significant Flavonoids
Acs Catalysis, 11, 2021
7XN9
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BU of 7xn9 by Molmil
Crystal structure of SSTR2 and L-054,522 complex
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Somatostatin receptor type 2,Endo-1,4-beta-xylanase, tert-butyl (2S)-6-azanyl-2-[[(2R,3S)-3-(1H-indol-3-yl)-2-[[4-(2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]carbonylamino]butanoyl]amino]hexanoate
著者Zhao, W, Han, S, Qiu, N, Feng, W, Lu, M, Yang, D, Wang, M.-W, Wu, B, Zhao, Q.
登録日2022-04-28
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insights into ligand recognition and selectivity of somatostatin receptors.
Cell Res., 32, 2022
7XNA
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BU of 7xna by Molmil
Crystal structure of somatostatin receptor 2 (SSTR2) with peptide antagonist CYN 154806
分子名称: CYN 154806, Somatostatin receptor type 2,Endo-1,4-beta-xylanase
著者Zhao, W, Han, S, Qiu, N, Feng, W, Lu, M, Yang, D, Wang, M.-W, Wu, B, Zhao, Q.
登録日2022-04-28
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural insights into ligand recognition and selectivity of somatostatin receptors.
Cell Res., 32, 2022
7XJX
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BU of 7xjx by Molmil
The cryo-EM structure of Fe3+ induced alpha-syn fibril.
分子名称: Alpha-synuclein
著者Zhao, Q.Y, Tao, Y.Q, Zhao, K, Tao, Y.Q, Li, D.
登録日2022-04-18
公開日2023-01-18
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural Insights of Fe3+ Induced alpha-synuclein Fibrillation in Parkinson' Disease
J.Mol.Biol., 435, 2023
7XR5
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BU of 7xr5 by Molmil
Crystal structure of imine reductase with NAPDH from Streptomyces albidoflavus
分子名称: 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57-nonadecaoxanonapentacontane-1,59-diol, 6-phosphogluconate dehydrogenase NAD-binding, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhang, J, Chen, R.C, Gao, S.S.
登録日2022-05-09
公開日2022-10-19
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Actinomycetes-derived imine reductases with a preference towards bulky amine substrates.
Commun Chem, 5, 2022
7XE8
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BU of 7xe8 by Molmil
Crystal structure of imine reductase from Streptomyces albidoflavus
分子名称: 6-phosphogluconate dehydrogenase NAD-binding
著者Zhang, J, Chen, R.C, Gao, S.S.
登録日2022-03-30
公開日2022-10-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Actinomycetes-derived imine reductases with a preference towards bulky amine substrates
Commun Chem, 5, 2022
6K20
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BU of 6k20 by Molmil
Structure of Apo YdiU
分子名称: MAGNESIUM ION, Protein adenylyltransferase SelO
著者Li, B, Yang, Y, Ma, Y.
登録日2019-05-13
公開日2020-05-13
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structure of Apo-YdiU
To Be Published
6HZ2
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BU of 6hz2 by Molmil
SOLUTION NMR STRUCTURE OF MAXIMIN 3 IN 50% TRIFLUOROETHANOL
分子名称: Maximins 3/H11 type 2
著者Benetti, S, Timmons, P.B, Hewage, C.M.
登録日2018-10-22
公開日2019-02-20
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献NMR model structure of the antimicrobial peptide maximin 3.
Eur.Biophys.J., 48, 2019
7X9Q
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BU of 7x9q by Molmil
Crystal structure of human STING complexed with compound BSP16
分子名称: (2R)-4-(5,6-dimethoxy-1-benzoselenophen-2-yl)-2-ethyl-4-oxidanylidene-butanoic acid, Stimulator of interferon genes protein
著者Pan, L, Guan, X, Feng, X, Li, Z, Bian, J.
登録日2022-03-15
公開日2022-09-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of Selenium-Containing STING Agonists as Orally Available Antitumor Agents.
J.Med.Chem., 65, 2022
7X9P
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BU of 7x9p by Molmil
Crystal structure of human STING complexed with compound BSP17
分子名称: 4-[6-methoxy-5-[3-[[6-methoxy-2-(4-oxidanyl-4-oxidanylidene-butanoyl)-1-benzoselenophen-5-yl]oxy]propoxy]-1-benzoselenophen-2-yl]-4-oxidanylidene-butanoic acid, Stimulator of interferon genes protein
著者Pan, L, Guan, X, Feng, X, Li, Z, Bian, J.
登録日2022-03-15
公開日2023-03-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Discovery of Selenium-containing STING agonists as orally available anti tumor agents
To be published
7VLM
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BU of 7vlm by Molmil
crystal structure of anti-CRISPR protein AcrIIA18
分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, H2C7, ...
著者Zhang, H, Wang, X.S, Li, X.Z.
登録日2021-10-04
公開日2021-12-01
最終更新日2023-07-05
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Inhibition mechanisms of CRISPR-Cas9 by AcrIIA17 and AcrIIA18
Nucleic Acids Res., 50, 2022
7WJQ
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BU of 7wjq by Molmil
Crystal structure of GSDMB in complex with Ipah7.8
分子名称: Isoform 2 of Gasdermin-B, Probable E3 ubiquitin-protein ligase ipaH7.8
著者Li, X, Zhang, H, Yin, H.
登録日2022-01-07
公開日2023-01-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Insights into the GSDMB-mediated cellular lysis and its targeting by IpaH7.8
Nat Commun, 14, 2023
7WNW
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BU of 7wnw by Molmil
Crystal structure of Imine Reductase Mutant(M5) from Actinoalloteichus hymeniacidonis in complex with NADPH
分子名称: 3-hydroxyisobutyrate dehydrogenase-like beta-hydroxyacid dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhand, J, Chen, R, Gao, S.
登録日2022-01-19
公開日2022-04-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Tuning an Imine Reductase for the Asymmetric Synthesis of Azacycloalkylamines by Concise Structure-Guided Engineering.
Angew.Chem.Int.Ed.Engl., 61, 2022
7WNN
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BU of 7wnn by Molmil
Crystal structure of Imine Reductase from Actinoalloteichus hymeniacidonis in complex with NADPH
分子名称: 3-hydroxyisobutyrate dehydrogenase-like beta-hydroxyacid dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhang, J, Chen, R, Gao, S.
登録日2022-01-19
公開日2022-04-06
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Tuning an Imine Reductase for the Asymmetric Synthesis of Azacycloalkylamines by Concise Structure-Guided Engineering.
Angew.Chem.Int.Ed.Engl., 61, 2022

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件を2024-06-12に公開中

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