8V52
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7EKN
| Crystal structure of AF10-ipep complex | 分子名称: | Protein AF-10, ipep | 著者 | Chen, S, Zhou, Z. | 登録日 | 2021-04-05 | 公開日 | 2021-04-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Structural characteristics of coiled-coil regions in AF10-DOT1L and AF10-inhibitory peptide complex. J Leukoc Biol, 110, 2021
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7EDP
| Crystal structure of AF10-DOT1L complex | 分子名称: | Histone-lysine N-methyltransferase, H3 lysine-79 specific, Protein AF-10 | 著者 | Chen, S, Zhou, Z. | 登録日 | 2021-03-16 | 公開日 | 2021-04-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural characteristics of coiled-coil regions in AF10-DOT1L and AF10-inhibitory peptide complex. J Leukoc Biol, 110, 2021
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8XAI
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7DE1
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5HLG
| Structure of reduced AbfR bound to DNA | 分子名称: | DNA (5'-D(*TP*AP*AP*CP*TP*CP*AP*AP*TP*CP*GP*CP*GP*CP*GP*CP*GP*AP*TP*TP*GP*AP*GP*T)-3'), MarR family transcriptional regulator | 著者 | Liu, G, Liu, X, Gan, J, Yang, C.G. | 登録日 | 2016-01-15 | 公開日 | 2017-01-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR. J. Am. Chem. Soc., 139, 2017
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7X5V
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5HLI
| Structure of Disulfide formed AbfR | 分子名称: | CHLORIDE ION, COPPER (II) ION, MarR family transcriptional regulator | 著者 | Liu, G, Liu, X, Gan, J, Yang, C.-G. | 登録日 | 2016-01-15 | 公開日 | 2017-01-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR. J. Am. Chem. Soc., 139, 2017
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6IMK
| The crystal structure of AsfvLIG:CG complex | 分子名称: | DNA (5'-D(*CP*CP*AP*GP*TP*CP*CP*GP*AP*CP*CP*CP*GP*CP*AP*TP*CP*CP*CP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*GP*GP*GP*AP*TP*GP*CP*GP*G)-3'), DNA (5'-D(P*GP*TP*CP*GP*GP*AP*CP*TP*GP*G)-3'), ... | 著者 | Chen, Y.Q, Gan, J.H. | 登録日 | 2018-10-23 | 公開日 | 2019-02-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | 主引用文献 | Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues. Nat Commun, 10, 2019
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6IMN
| The crystal structure of AsfvLIG:CT2 complex | 分子名称: | CHLORIDE ION, DNA (5'-D(*CP*CP*AP*GP*TP*CP*CP*GP*AP*CP*CP*CP*GP*CP*AP*TP*CP*CP*CP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*GP*GP*GP*AP*TP*GP*CP*GP*TP*GP*TP*CP*GP*GP*AP*CP*TP*GP*G)-3'), ... | 著者 | Chen, Y.Q, Gan, J.H. | 登録日 | 2018-10-23 | 公開日 | 2019-02-27 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues. Nat Commun, 10, 2019
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6IML
| The crystal structure of AsfvLIG:CT1 complex | 分子名称: | DNA (5'-D(*CP*CP*AP*GP*TP*CP*CP*GP*AP*CP*CP*CP*GP*CP*AP*TP*CP*CP*CP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*GP*GP*GP*AP*TP*GP*CP*GP*T)-3'), DNA (5'-D(P*GP*TP*CP*GP*GP*AP*CP*TP*GP*G)-3'), ... | 著者 | Chen, Y.Q, Gan, J.H. | 登録日 | 2018-10-23 | 公開日 | 2019-02-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues. Nat Commun, 10, 2019
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7XR4
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7XR6
| Structure of human excitatory amino acid transporter 2 (EAAT2) in complex with WAY-213613 | 分子名称: | (2S)-2-azanyl-4-[[4-[2-bromanyl-4,5-bis(fluoranyl)phenoxy]phenyl]amino]-4-oxidanylidene-butanoic acid, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Zhao, Y, Zhang, Z. | 登録日 | 2022-05-09 | 公開日 | 2022-06-22 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of ligand binding modes of human EAAT2. Nat Commun, 13, 2022
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6IMJ
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7WY5
| ADGRL3/Gq complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Isoform 3 of Adhesion G protein-coupled receptor L3, ... | 著者 | He, Y, Qian, Y. | 登録日 | 2022-02-15 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-30 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Structural insights into adhesion GPCR ADGRL3 activation and Gq, Gs, Gi, and G12 coupling. Mol.Cell, 82, 2022
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7WY8
| ADGRL3/Gs complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Isoform 3 of Adhesion G protein-coupled receptor L3, ... | 著者 | He, Y, Qian, Y. | 登録日 | 2022-02-15 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-30 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Structural insights into adhesion GPCR ADGRL3 activation and Gq, Gs, Gi, and G12 coupling Mol.Cell, 82, 2022
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7WYB
| ADGRL3/Gi complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | He, Y, Qian, Y. | 登録日 | 2022-02-15 | 公開日 | 2022-10-26 | 最終更新日 | 2022-11-30 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Structural insights into adhesion GPCR ADGRL3 activation and G q , G s , G i , and G 12 coupling. Mol.Cell, 82, 2022
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7X10
| ADGRL3/miniG12 complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Isoform 3 of Adhesion G protein-coupled receptor L3, ... | 著者 | He, Y, Qian, Y. | 登録日 | 2022-02-22 | 公開日 | 2022-11-09 | 最終更新日 | 2022-11-30 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Structural insights into adhesion GPCR ADGRL3 activation and Gq, Gs, Gi, and G12 coupling. Mol.Cell, 82, 2022
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8K9V
| Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 3 (ADKI3) | 分子名称: | GLYCEROL, LYSINE, Lysine--tRNA ligase, ... | 著者 | Zhou, J, Xia, M, Yang, G, Li, P, Fang, P. | 登録日 | 2023-08-01 | 公開日 | 2024-06-26 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors. Commun Biol, 7, 2024
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8K9X
| Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 5 (ADKI5) | 分子名称: | (2~{S})-2,6-bis(azanyl)-~{N}-[3-[2-[[4-[(2,5-dimethoxyphenyl)amino]-1,3,5-triazin-2-yl]amino]phenyl]sulfonylpropyl]hexanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Lysine--tRNA ligase | 著者 | Zhou, J, Xia, M, Yang, G, Li, P, Fang, P. | 登録日 | 2023-08-01 | 公開日 | 2024-06-26 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors. Commun Biol, 7, 2024
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8K9S
| Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 1 (ADKI1) | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LYSINE, Lysine--tRNA ligase, ... | 著者 | Zhou, J, Xia, M, Yang, G, Li, P, Fang, P. | 登録日 | 2023-08-01 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors. Commun Biol, 7, 2024
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8K9U
| Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 2 (ADKI2) | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LYSINE, Lysine--tRNA ligase, ... | 著者 | Zhou, J, Xia, M, Yang, G, Li, P, Fang, P. | 登録日 | 2023-08-01 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors. Commun Biol, 7, 2024
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8K9W
| Crystal structure of plasmodium LysRS complexing with ASP3026 derived LysRS inhibitor 4 (ADKI4) | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Lysine--tRNA ligase, ~{N}2-(2-methoxyphenyl)-~{N}4-(2-propan-2-ylsulfonylphenyl)-1,3,5-triazine-2,4-diamine | 著者 | Zhou, J, Xia, M, Yang, G, Li, P, Fang, P. | 登録日 | 2023-08-01 | 公開日 | 2024-06-26 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-guided conversion from an anaplastic lymphoma kinase inhibitor into Plasmodium lysyl-tRNA synthetase selective inhibitors. Commun Biol, 7, 2024
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6ITS
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6J1L
| Crystal Structure Analysis of the ROR gamma(C455E) | 分子名称: | 2-[4-(ethylsulfonyl)phenyl]-N-[2'-fluoro-4'-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)[1,1'-biphenyl]-4-yl]acetamide, Nuclear receptor ROR-gamma | 著者 | zhang, Y, Li, C.C, wu, X.S. | 登録日 | 2018-12-28 | 公開日 | 2019-05-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable ROR gamma Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer. J.Med.Chem., 62, 2019
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