3Q67
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3SB5
| Zn-mediated Trimer of T4 Lysozyme R125C/E128C by Synthetic Symmetrization | 分子名称: | CHLORIDE ION, GLYCEROL, Lysozyme, ... | 著者 | Laganowsky, A, Soriaga, A.B, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O. | 登録日 | 2011-06-03 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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3SB6
| Cu-mediated Dimer of T4 Lysozyme D61H/K65H/R76H/R80H by Synthetic Symmetrization | 分子名称: | CHLORIDE ION, COPPER (II) ION, Lysozyme | 著者 | Soriaga, A.B, Laganowsky, A, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O. | 登録日 | 2011-06-03 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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3SEV
| Zn-mediated Trimer of Maltose-binding Protein E310H/K314H by Synthetic Symmetrization | 分子名称: | CHLORIDE ION, Maltose-binding periplasmic protein, ZINC ION, ... | 著者 | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | 登録日 | 2011-06-11 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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3TH3
| Mg2+ Is Required for Optimal Folding of the Gamma-Carboxyglutamic Acid (Gla) Domains of Vitamin K-Dependent Clotting Factors At Physiological Ca2+ | 分子名称: | CALCIUM ION, CHLORIDE ION, Coagulation factor VII heavy chain, ... | 著者 | Vadivel, K, Agah, S, Cascio, D, Padmanabhan, K, Bajaj, S.P. | 登録日 | 2011-08-18 | 公開日 | 2012-08-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Mg2+ Is Required for Optimal Folding of the Gamma-Carboxyglutamic Acid (Gla)
Domains of Vitamin K-Dependent Clotting Factors At Physiological Ca2+ To be Published
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3TH2
| Mg2+ Is Required for Optimal Folding of the Gamma-Carboxyglutamic Acid (Gla) Domains of Vitamin K-Dependent Clotting Factors At Physiological Ca2+ | 分子名称: | BENZAMIDINE, CALCIUM ION, CHLORIDE ION, ... | 著者 | Vadivel, K, Agah, S, Cascio, D, Padmanabhan, K, Bajaj, S.P. | 登録日 | 2011-08-18 | 公開日 | 2012-08-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Mg2+ Is Required for Optimal Folding of the Gamma-Carboxyglutamic Acid (Gla)
Domains of Vitamin K-Dependent Clotting Factors At Physiological Ca2+ To be Published
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3Q65
| Human Aldose Reductase in Complex with NADP+ in Space Group P212121 | 分子名称: | Aldose reductase, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Sawaya, M.R, Cascio, D, Balendiran, G.K. | 登録日 | 2010-12-30 | 公開日 | 2011-01-19 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | The role of Cys-298 in aldose reductase function. J.Biol.Chem., 286, 2011
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3TH4
| Mg2+ Is Required for Optimal Folding of the Gamma-Carboxyglutamic Acid (Gla) Domains of Vitamin K-Dependent Clotting Factors At Physiological Ca2+ | 分子名称: | CALCIUM ION, CHLORIDE ION, Coagulation factor VII heavy chain, ... | 著者 | Vadivel, K, Agah, S, Cascio, D, Padmanabhan, K, Bajaj, S.P. | 登録日 | 2011-08-18 | 公開日 | 2012-08-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Mg2+ Is Required for Optimal Folding of the Gamma-Carboxyglutamic Acid (Gla)
Domains of Vitamin K-Dependent Clotting Factors At Physiological Ca2+ To be Published
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1MQ7
| CRYSTAL STRUCTURE OF DUTPASE FROM MYCOBACTERIUM TUBERCULOSIS (RV2697C) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE | 著者 | Sawaya, M.R, Chan, S, Segelke, B.W, Lekin, T, Heike, K, Cho, U.S, Naranjo, C, Perry, L.J, Yeates, T.O, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2002-09-13 | 公開日 | 2002-10-09 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of the Mycobacterium tuberculosis dUTPase: insights into the catalytic mechanism. J.Mol.Biol., 341, 2004
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2LGS
| FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE | 分子名称: | GLUTAMIC ACID, GLUTAMINE SYNTHETASE, MANGANESE (II) ION | 著者 | Liaw, S.-H, Eisenberg, D. | 登録日 | 1994-08-05 | 公開日 | 1994-11-30 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Feedback inhibition of fully unadenylylated glutamine synthetase from Salmonella typhimurium by glycine, alanine, and serine. Proc.Natl.Acad.Sci.USA, 90, 1993
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5VL4
| Accidental minimum contact crystal lattice formed by a redesigned protein oligomer | 分子名称: | T33-53H-B | 著者 | Cannon, K.A, Cascio, D, Sawaya, M.R, Park, R, Boyken, S, King, N, Yeates, T. | 登録日 | 2017-04-24 | 公開日 | 2018-05-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | Design and structure of two new protein cages illustrate successes and ongoing challenges in protein engineering. Protein Sci., 29, 2020
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8FQ7
| Nanobody with WIW inserted in CDR3 loop to Inhibit Growth of Alzheimer's Tau fibrils | 分子名称: | GLYCEROL, Nanobody with WIW insert in CDR3 loop to target tau fibrils | 著者 | Abskharon, R, Sawaya, M.R, Cascio, D.C, Eisenberg, D.S. | 登録日 | 2023-01-05 | 公開日 | 2023-10-04 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils. Proc.Natl.Acad.Sci.USA, 120, 2023
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1RLD
| SOLID-STATE PHASE TRANSITION IN THE CRYSTAL STRUCTURE OF RIBULOSE 1,5-BIPHOSPHATE CARBOXYLASE(SLASH)OXYGENASE | 分子名称: | RIBULOSE 1,5 BISPHOSPHATE CARBOXYLASE/OXYGENASE (LARGE CHAIN), RIBULOSE 1,5 BISPHOSPHATE CARBOXYLASE/OXYGENASE (SMALL CHAIN) | 著者 | Zhang, K.Y.J, Eisenberg, D. | 登録日 | 1993-12-10 | 公開日 | 1994-04-30 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Solid-state phase transition in the crystal structure of ribulose 1,5-bisphosphate carboxylase/oxygenase. Acta Crystallogr.,Sect.D, 50, 1994
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6WX1
| Antigen Binding Fragment of OKT9 | 分子名称: | GLYCEROL, OKT9 Fab Heavy Chain, OKT9 Fab Light Chain | 著者 | Rodriguez, J.A, Helguera, G, Sawaya, M, Cascio, D, Collazo, M, Flores, M, Zink, S, Ferrero, S, Payes, C, Fuentes, D, Short, C. | 登録日 | 2020-05-09 | 公開日 | 2021-05-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Antibody-Based Inhibition of Pathogenic New World Hemorrhagic Fever Mammarenaviruses by Steric Occlusion of the Human Transferrin Receptor 1 Apical Domain. J.Virol., 95, 2021
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4UNU
| MCG - a dimer of lambda variable domains | 分子名称: | IG LAMBDA CHAIN V-II REGION MGC, POLYETHYLENE GLYCOL (N=34), SULFATE ION | 著者 | Brumshtein, B, Esswein, S.R, Landau, M, Ryan, C, Whitelegge, J, Casio, D, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2014-05-30 | 公開日 | 2014-08-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | 主引用文献 | Formation of Amyloid Fibers by Monomeric Light-Chain Variable Domains. J.Biol.Chem., 289, 2014
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6I9J
| Human transforming growth factor beta2 in a tetragonal crystal form | 分子名称: | Transforming growth factor beta-2 proprotein | 著者 | Gomis-Ruth, F.X, Marino-Puertas, L, del Amo-Maestro, L, Goulas, T. | 登録日 | 2018-11-23 | 公開日 | 2019-07-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Recombinant production, purification, crystallization, and structure analysis of human transforming growth factor beta 2 in a new conformation. Sci Rep, 9, 2019
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4UNV
| Covalent dimer of lambda variable domains | 分子名称: | IG LAMBDA CHAIN V-II REGION MGC, SULFATE ION | 著者 | Brumshtein, B, Esswein, S, Landau, M, Ryan, C, Whitelegge, J, Sawaya, M, Eisenberg, D.S. | 登録日 | 2014-05-30 | 公開日 | 2014-08-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Formation of Amyloid Fibers by Monomeric Light-Chain Variable Domains. J.Biol.Chem., 289, 2014
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2DPK
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7QX4
| mosquitocidal Cry11Aa determined at pH 7 from naturally-occurring nanocrystals by Serial femtosecond crystallography | 分子名称: | Pesticidal crystal protein Cry11Aa | 著者 | De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P. | 登録日 | 2022-01-26 | 公開日 | 2022-07-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals. Nat Commun, 13, 2022
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7QX6
| mosquitocidal Cry11Aa-E583Q determined at pH 7 from naturally-occurring nanocrystals by Serial femtosecond crystallography | 分子名称: | Pesticidal crystal protein Cry11Aa | 著者 | De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P. | 登録日 | 2022-01-26 | 公開日 | 2022-07-27 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals. Nat Commun, 13, 2022
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7QX5
| mosquitocidal Cry11Aa-Y449F determined at pH 7 from naturally-occurring nanocrystals by Serial femtosecond crystallography | 分子名称: | Pesticidal crystal protein Cry11Aa | 著者 | De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P. | 登録日 | 2022-01-26 | 公開日 | 2022-07-27 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals. Nat Commun, 13, 2022
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7QX7
| mosquitocidal Cry11Aa-F17Y determined at pH 7 from naturally-occurring nanocrystals by Serial femtosecond crystallography | 分子名称: | Pesticidal crystal protein Cry11Aa | 著者 | De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P. | 登録日 | 2022-01-26 | 公開日 | 2022-07-27 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals. Nat Commun, 13, 2022
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2Y29
| Structure of segment KLVFFA from the amyloid-beta peptide (Ab, residues 16-21), alternate polymorph III | 分子名称: | AMYLOID BETA A4 PROTEIN | 著者 | Colletier, J, Laganowsky, A, Sawaya, M.R, Eisenberg, D. | 登録日 | 2010-12-14 | 公開日 | 2011-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular Basis for Amyloid-{Beta} Polymorphism. Proc.Natl.Acad.Sci.USA, 108, 2011
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2Y3L
| Structure of segment MVGGVVIA from the amyloid-beta peptide (Ab, residues 35-42), alternate polymorph 2 | 分子名称: | AMYLOID BETA A4 PROTEIN | 著者 | Colletier, J.P, Laganowsky, A, Sawaya, M.R, Eisenberg, D. | 登録日 | 2010-12-21 | 公開日 | 2011-11-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Molecular Basis for Amyloid-{Beta} Polymorphism. Proc.Natl.Acad.Sci.USA, 108, 2011
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2Y3K
| Structure of segment MVGGVVIA from the amyloid-beta peptide (Ab, residues 35-42), alternate polymorph 1 | 分子名称: | AMYLOID BETA A4 PROTEIN | 著者 | Colletier, J.P, Laganowsky, A, Sawaya, M.R, Eisenberg, D. | 登録日 | 2010-12-21 | 公開日 | 2011-11-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular Basis for Amyloid-{Beta} Polymorphism. Proc.Natl.Acad.Sci.USA, 108, 2011
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