4TNF
 
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4TLS
 | | Crystal Structure of Human Transthyretin Glu92Pro Mutant | | 分子名称: | GLYCEROL, PHOSPHATE ION, SODIUM ION, ... | | 著者 | Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. | | 登録日 | 2014-05-30 | | 公開日 | 2015-10-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
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4PCK
 | | Crystal structure of the P22S mutant of N-terminal CS domain of human Shq1 | | 分子名称: | GLYCEROL, Protein SHQ1 homolog | | 著者 | Singh, M, Wang, Z, Cascio, D, Feigon, J. | | 登録日 | 2014-04-15 | | 公開日 | 2015-01-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | | 主引用文献 | Structure and Interactions of the CS Domain of Human H/ACA RNP Assembly Protein Shq1.
J.Mol.Biol., 427, 2015
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4TNE
 | | Crystal Structure of Human Transthyretin Thr119Tyr Mutant | | 分子名称: | GLYCEROL, Transthyretin | | 著者 | Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. | | 登録日 | 2014-06-03 | | 公開日 | 2015-10-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
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4TLT
 | | Crystal structure of human transthyretin | | 分子名称: | MAGNESIUM ION, Transthyretin | | 著者 | Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. | | 登録日 | 2014-05-30 | | 公開日 | 2015-10-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
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4RC1
 | | Structure of the methanofuran/methanopterin biosynthetic enzyme MJ1099 from Methanocaldococcus jannaschii with PRPP | | 分子名称: | PHOSPHATE ION, UPF0264 protein MJ1099 | | 著者 | Bobik, T.A, Morales, E.J, Cascio, D, Sawaya, M.R, Yeates, T.O, Rasche, M.E. | | 登録日 | 2014-09-14 | | 公開日 | 2014-11-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of the methanofuran/methanopterin-biosynthetic enzyme MJ1099 from Methanocaldococcus jannaschii.
Acta Crystallogr F Struct Biol Commun, 70, 2014
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4TM6
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4TM9
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4TLK
 | | Crystal Structure of Human Transthyretin Ser85Pro/Glu92Pro Mutant | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, SODIUM ION, ... | | 著者 | Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. | | 登録日 | 2014-05-30 | | 公開日 | 2015-10-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
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8FQ7
 | | Nanobody with WIW inserted in CDR3 loop to Inhibit Growth of Alzheimer's Tau fibrils | | 分子名称: | GLYCEROL, Nanobody with WIW insert in CDR3 loop to target tau fibrils | | 著者 | Abskharon, R, Sawaya, M.R, Cascio, D.C, Eisenberg, D.S. | | 登録日 | 2023-01-05 | | 公開日 | 2023-10-04 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils.
Proc.Natl.Acad.Sci.USA, 120, 2023
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1RLD
 | | SOLID-STATE PHASE TRANSITION IN THE CRYSTAL STRUCTURE OF RIBULOSE 1,5-BIPHOSPHATE CARBOXYLASE(SLASH)OXYGENASE | | 分子名称: | RIBULOSE 1,5 BISPHOSPHATE CARBOXYLASE/OXYGENASE (LARGE CHAIN), RIBULOSE 1,5 BISPHOSPHATE CARBOXYLASE/OXYGENASE (SMALL CHAIN) | | 著者 | Zhang, K.Y.J, Eisenberg, D. | | 登録日 | 1993-12-10 | | 公開日 | 1994-04-30 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Solid-state phase transition in the crystal structure of ribulose 1,5-bisphosphate carboxylase/oxygenase.
Acta Crystallogr.,Sect.D, 50, 1994
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1LNX
 | | Crystal structure of the P.aerophilum SmAP1 heptamer in a new crystal form (C2221) | | 分子名称: | ACETIC ACID, GLYCEROL, URIDINE, ... | | 著者 | Mura, C, Kozhukhovsky, A, Eisenberg, D. | | 登録日 | 2002-05-04 | | 公開日 | 2003-03-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs)
Protein Sci., 12, 2003
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5KBA
 | | Computational Design of Self-Assembling Cyclic Protein Homooligomers | | 分子名称: | Designed protein ANK1C2 | | 著者 | Sankaran, B, Zwart, P.H, Fallas, J.A, Pereira, J.H, Ueda, G, Baker, D. | | 登録日 | 2016-06-02 | | 公開日 | 2017-04-12 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | | 主引用文献 | Computational design of self-assembling cyclic protein homo-oligomers.
Nat Chem, 9, 2017
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5K7V
 | | Computational Design of Self-Assembling Cyclic Protein Homooligomers | | 分子名称: | Designed protein HR00C3 | | 著者 | Sankaran, B, Zwart, P.H, Fallas, J.A, Pereira, J.H, Ueda, G, Baker, D. | | 登録日 | 2016-05-26 | | 公開日 | 2017-04-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.165 Å) | | 主引用文献 | Computational design of self-assembling cyclic protein homo-oligomers.
Nat Chem, 9, 2017
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4UNU
 | | MCG - a dimer of lambda variable domains | | 分子名称: | IG LAMBDA CHAIN V-II REGION MGC, POLYETHYLENE GLYCOL (N=34), SULFATE ION | | 著者 | Brumshtein, B, Esswein, S.R, Landau, M, Ryan, C, Whitelegge, J, Casio, D, Sawaya, M.R, Eisenberg, D.S. | | 登録日 | 2014-05-30 | | 公開日 | 2014-08-27 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | | 主引用文献 | Formation of Amyloid Fibers by Monomeric Light-Chain Variable Domains.
J.Biol.Chem., 289, 2014
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8V9O
 | | Imaging scaffold engineered to bind the therapeutic protein target BARD1 | | 分子名称: | CALCIUM ION, Tetrahedral Nanocage Cage Component Fused to Anti-BARD1 Darpin, Tetrahedral Nanocage Cage, ... | | 著者 | Agdanowski, M.P, Castells-Graells, R, Sawaya, M.R, Yeates, T.O, Arbing, M.A. | | 登録日 | 2023-12-08 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (3.81 Å) | | 主引用文献 | X-ray crystal structure of a designed rigidified imaging scaffold in the ligand-free conformation.
Acta Crystallogr.,Sect.F, 80, 2024
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5UI2
 | | CRYSTAL STRUCTURE OF ORANGE CAROTENOID PROTEIN | | 分子名称: | (3'R)-3'-hydroxy-beta,beta-caroten-4-one, CHLORIDE ION, Orange carotenoid-binding protein, ... | | 著者 | KERFELD, C.A, SAWAYA, M.R, VISHNU, B, KROGMANN, D, YEATES, T.O. | | 登録日 | 2017-01-12 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The crystal structure of a cyanobacterial water-soluble carotenoid binding protein.
Structure, 11, 2003
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4UNV
 | | Covalent dimer of lambda variable domains | | 分子名称: | IG LAMBDA CHAIN V-II REGION MGC, SULFATE ION | | 著者 | Brumshtein, B, Esswein, S, Landau, M, Ryan, C, Whitelegge, J, Sawaya, M, Eisenberg, D.S. | | 登録日 | 2014-05-30 | | 公開日 | 2014-08-27 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Formation of Amyloid Fibers by Monomeric Light-Chain Variable Domains.
J.Biol.Chem., 289, 2014
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2Y29
 | | Structure of segment KLVFFA from the amyloid-beta peptide (Ab, residues 16-21), alternate polymorph III | | 分子名称: | AMYLOID BETA A4 PROTEIN | | 著者 | Colletier, J, Laganowsky, A, Sawaya, M.R, Eisenberg, D. | | 登録日 | 2010-12-14 | | 公開日 | 2011-10-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Molecular Basis for Amyloid-{Beta} Polymorphism.
Proc.Natl.Acad.Sci.USA, 108, 2011
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2Y3L
 | | Structure of segment MVGGVVIA from the amyloid-beta peptide (Ab, residues 35-42), alternate polymorph 2 | | 分子名称: | AMYLOID BETA A4 PROTEIN | | 著者 | Colletier, J.P, Laganowsky, A, Sawaya, M.R, Eisenberg, D. | | 登録日 | 2010-12-21 | | 公開日 | 2011-11-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Molecular Basis for Amyloid-{Beta} Polymorphism.
Proc.Natl.Acad.Sci.USA, 108, 2011
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2Y3J
 | | Structure of segment AIIGLM from the amyloid-beta peptide (Ab, residues 30-35) | | 分子名称: | AMYLOID BETA A4 PROTEIN | | 著者 | Colletier, J.P, Laganowsky, A, Sawaya, M.R, Eisenberg, D. | | 登録日 | 2010-12-21 | | 公開日 | 2011-11-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Molecular Basis for Amyloid-{Beta} Polymorphism.
Proc.Natl.Acad.Sci.USA, 108, 2011
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2Y3K
 | | Structure of segment MVGGVVIA from the amyloid-beta peptide (Ab, residues 35-42), alternate polymorph 1 | | 分子名称: | AMYLOID BETA A4 PROTEIN | | 著者 | Colletier, J.P, Laganowsky, A, Sawaya, M.R, Eisenberg, D. | | 登録日 | 2010-12-21 | | 公開日 | 2011-11-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Molecular Basis for Amyloid-{Beta} Polymorphism.
Proc.Natl.Acad.Sci.USA, 108, 2011
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2Y2A
 | | Structure of segment KLVFFA from the amyloid-beta peptide (Ab, residues 16-21), alternate polymorph I | | 分子名称: | ACETATE ION, AMYLOID BETA A4 PROTEIN | | 著者 | Colletier, J, Laganowsky, A, Sawaya, M.R, Eisenberg, D. | | 登録日 | 2010-12-14 | | 公開日 | 2011-10-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Molecular Basis for Amyloid-{Beta} Polymorphism.
Proc.Natl.Acad.Sci.USA, 108, 2011
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6I9J
 | | Human transforming growth factor beta2 in a tetragonal crystal form | | 分子名称: | Transforming growth factor beta-2 proprotein | | 著者 | Gomis-Ruth, F.X, Marino-Puertas, L, del Amo-Maestro, L, Goulas, T. | | 登録日 | 2018-11-23 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Recombinant production, purification, crystallization, and structure analysis of human transforming growth factor beta 2 in a new conformation.
Sci Rep, 9, 2019
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2GLS
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