2CXP
 
 | | Crystal structure of mouse AMF / A5P complex | | 分子名称: | ARABINOSE-5-PHOSPHATE, GLYCEROL, Glucose-6-phosphate isomerase | | 著者 | Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T. | | 登録日 | 2005-06-30 | | 公開日 | 2006-05-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
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2E8J
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2CVP
 | | Crystal structure of mouse AMF | | 分子名称: | ACETATE ION, GLYCEROL, Glucose-6-phosphate isomerase | | 著者 | Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T. | | 登録日 | 2005-06-10 | | 公開日 | 2006-05-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
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2CXQ
 | | Crystal structure of mouse AMF / S6P complex | | 分子名称: | D-SORBITOL-6-PHOSPHATE, GLYCEROL, Glucose-6-phosphate isomerase | | 著者 | Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T. | | 登録日 | 2005-06-30 | | 公開日 | 2006-05-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
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2CXS
 | | Crystal structure of mouse AMF / F6P complex | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, GLYCEROL, Glucose-6-phosphate isomerase | | 著者 | Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T. | | 登録日 | 2005-06-30 | | 公開日 | 2006-05-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
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2CXR
 | | Crystal structure of mouse AMF / 6PG complex | | 分子名称: | 6-PHOSPHOGLUCONIC ACID, GLYCEROL, Glucose-6-phosphate isomerase | | 著者 | Tanaka, N, Haga, A, Naba, N, Shiraiwa, K, Kusakabe, Y, Hashimoto, K, Funasaka, T, Nagase, H, Raz, A, Nakamura, K.T. | | 登録日 | 2005-06-30 | | 公開日 | 2006-05-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors
J.Mol.Biol., 356, 2006
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2DLC
 | | Crystal structure of the ternary complex of yeast tyrosyl-tRNA synthetase | | 分子名称: | MAGNESIUM ION, O-(ADENOSINE-5'-O-YL)-N-(L-TYROSYL)PHOSPHORAMIDATE, T-RNA (76-MER), ... | | 著者 | Tsunoda, M, Kusakabe, Y, Tanaka, N, Nakamura, K.T. | | 登録日 | 2006-04-18 | | 公開日 | 2007-06-12 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for recognition of cognate tRNA by tyrosyl-tRNA synthetase from three kingdoms.
Nucleic Acids Res., 35, 2007
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5B13
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5XQZ
 | | Structure of the MOB1-NDR2 complex | | 分子名称: | GLYCEROL, MOB kinase activator 1A, Serine/threonine-protein kinase 38-like, ... | | 著者 | Wu, G, Lin, K. | | 登録日 | 2017-06-07 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control.
Nat Commun, 8, 2017
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3ATG
 | | endo-1,3-beta-glucanase from Cellulosimicrobium cellulans | | 分子名称: | CALCIUM ION, GLUCANASE, GLYCEROL, ... | | 著者 | Tanabe, Y, Pang, Z, Oda, M, Mikami, B. | | 登録日 | 2011-01-04 | | 公開日 | 2012-01-18 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Structural and thermodynamic characterization of endo-1,3-beta-glucanase: Insights into the substrate recognition mechanism.
Biochim. Biophys. Acta, 1866, 2018
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2RPP
 | | Solution structure of Tandem zinc finger domain 12 in Muscleblind-like protein 2 | | 分子名称: | Muscleblind-like protein 2, ZINC ION | | 著者 | Abe, C, Dang, W, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2008-06-24 | | 公開日 | 2009-05-12 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the RNA binding domain in the human muscleblind-like protein 2
Protein Sci., 18, 2009
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8IG0
 | | Crystal structure of menin in complex with DS-1594b | | 分子名称: | (1R,2S,4R)-4-[[4-(5,6-dimethoxypyridazin-3-yl)phenyl]methylamino]-2-[methyl-[6-[2,2,2-tris(fluoranyl)ethyl]thieno[2,3-d]pyrimidin-4-yl]amino]cyclopentan-1-ol, DIMETHYL SULFOXIDE, Menin, ... | | 著者 | Suzuki, M, Yoneyama, T, Imai, E. | | 登録日 | 2023-02-20 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1.
Cancer Cell Int, 23, 2023
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3WO8
 | | Crystal structure of the beta-N-acetylglucosaminidase from Thermotoga maritima | | 分子名称: | Beta-N-acetylglucosaminidase | | 著者 | Mine, S, Kado, Y, Watanabe, M, Inoue, T, Ishikawa, K. | | 登録日 | 2013-12-20 | | 公開日 | 2014-12-24 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | The structure of hyperthermophilic beta-N-acetylglucosaminidase reveals a novel dimer architecture associated with the active site.
Febs J., 281, 2014
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1RFP
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1KXX
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1KXY
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1KXW
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7VGP
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7VGO
 | | Hen egg lysozyme | | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | | 著者 | Oda, M, Ikura, T, Ito, N. | | 登録日 | 2021-09-17 | | 公開日 | 2022-02-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structural Analysis of Hen Egg Lysozyme Refolded after Denaturation at Acidic pH.
Protein J., 41, 2022
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5YY4
 | | Crystal structure of the scFv antibody 4B08 with sulfated epitope peptide | | 分子名称: | C-C chemokine receptor type 5, CHLORIDE ION, SULFATE ION, ... | | 著者 | Caaveiro, J.M.M, Miyanabe, K, Tsumoto, K. | | 登録日 | 2017-12-07 | | 公開日 | 2018-07-18 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Tyrosine Sulfation Restricts the Conformational Ensemble of a Flexible Peptide, Strengthening the Binding Affinity for an Antibody
Biochemistry, 57, 2018
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2E5S
 | | Solution structure of the zf-CCCHx2 domain of muscleblind-like 2, isoform 1 [Homo sapiens] | | 分子名称: | OTTHUMP00000018578, ZINC ION | | 著者 | Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-12-22 | | 公開日 | 2007-06-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the RNA binding domain in the human muscleblind-like protein 2
Protein Sci., 18, 2009
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2ZTB
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3VJK
 | | Crystal structure of human depiptidyl peptidase IV (DPP-4) in complex with MP-513 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, ... | | 著者 | Akahoshi, F, Kishida, H, Miyaguchi, I, Yoshida, T, Ishii, S. | | 登録日 | 2011-10-24 | | 公開日 | 2012-10-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl]thiazolidine): A highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Bioorg.Med.Chem., 20, 2012
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3VJL
 | | Crystal structure of human depiptidyl peptidase IV (DPP-4) in complex with a prolylthiazolidine inhibitor #2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, ... | | 著者 | Akahoshi, F, Kishida, H, Miyaguchi, I, Yoshida, T, Ishii, S. | | 登録日 | 2011-10-24 | | 公開日 | 2012-10-24 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.393 Å) | | 主引用文献 | Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl]thiazolidine): A highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Bioorg.Med.Chem., 20, 2012
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2E7A
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