4C0C
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![BU of 4c0c by Molmil](/molmil-images/mine/4c0c) | Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-4-(4-(2,4-difluorophenyl)piperazin-1-yl)-2-fluorobenzamide. | 分子名称: | 4-[4-[2,4-bis(fluoranyl)phenyl]piperazin-1-yl]-2-fluoranyl-N-[(2R)-3-(1H-indol-3-yl)-1-oxidanylidene-1-(pyridin-4-ylamino)propan-2-yl]benzamide, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Calvet, C.M, Vieira, D.F, Choi, J.Y, Cameron, M.D, Gut, J, Kellar, D, Siqueira-Neto, J.L, McKerrow, J.H, Roush, W.R, Podust, L.M. | 登録日 | 2013-08-01 | 公開日 | 2014-08-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | 4-Aminopyridyl-Based Cyp51 Inhibitors as Anti-Trypanosoma Cruzi Drug Leads with Improved Pharmacokinetic Profile and in Vivo Potency. J.Med.Chem., 57, 2014
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4DC1
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6HXW
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![BU of 6hxw by Molmil](/molmil-images/mine/6hxw) | structure of human CD73 in complex with antibody IPH53 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-nucleotidase, IPH53 heavy chain, ... | 著者 | Roussel, A, Amigues, B. | 登録日 | 2018-10-18 | 公開日 | 2019-08-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies. Cell Rep, 27, 2019
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2MQ1
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1HHI
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![BU of 1hhi by Molmil](/molmil-images/mine/1hhi) | THE ANTIGENIC IDENTITY OF PEPTIDE(SLASH)MHC COMPLEXES: A COMPARISON OF THE CONFORMATION OF FIVE PEPTIDES PRESENTED BY HLA-A2 | 分子名称: | BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A*0201) (ALPHA CHAIN), INFLUENZA A MATRIX PROTEIN M1 (RESIDUES 58-66) | 著者 | Madden, D.R, Garboczi, D.N, Wiley, D.C. | 登録日 | 1993-06-30 | 公開日 | 1993-10-31 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2. Cell(Cambridge,Mass.), 75, 1993
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1DIW
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![BU of 1diw by Molmil](/molmil-images/mine/1diw) | THE HC FRAGMENT OF TETANUS TOXIN COMPLEXED WITH GALACTOSE | 分子名称: | TETANUS TOXIN HC, beta-D-galactopyranose | 著者 | Emsley, P, Fotinou, C, Black, I, Fairweather, N.F, Charles, I.G, Watts, C, Hewitt, E, Isaacs, N.W. | 登録日 | 1999-11-30 | 公開日 | 2000-03-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The structures of the H(C) fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside binding. J.Biol.Chem., 275, 2000
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2JUU
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![BU of 2juu by Molmil](/molmil-images/mine/2juu) | allo-ThrA3 DKP-insulin | 分子名称: | Insulin A chain, Insulin B chain | 著者 | Huang, K, Chan, S, Hua, Q, Chu, Y, Wang, R, Klaproth, B, Jia, W, Whittaker, J, De Meyts, P, Nakagawa, S.H, Steiner, D.F, Katsoyannis, P.G, Weiss, M.A. | 登録日 | 2007-09-03 | 公開日 | 2007-10-16 | 最終更新日 | 2021-10-20 | 実験手法 | SOLUTION NMR | 主引用文献 | The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE. J.Biol.Chem., 282, 2007
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1DLL
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![BU of 1dll by Molmil](/molmil-images/mine/1dll) | The HC fragement of tetanus toxin complexed with lactose | 分子名称: | GLYCEROL, TETANUS TOXIN, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | 著者 | Emsley, P, Fotinou, C, Black, I, Fairweather, N.F, Charles, I.G, Watts, C, Hewitt, E, Isaacs, N.W. | 登録日 | 1999-12-10 | 公開日 | 2000-03-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The structures of the H(C) fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside binding. J.Biol.Chem., 275, 2000
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2JUM
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![BU of 2jum by Molmil](/molmil-images/mine/2jum) | ThrA3-DKP-insulin | 分子名称: | Insulin A chain, Insulin B chain | 著者 | Huang, K, Chan, S, Hua, Q, Chu, Y, Wang, R, Klaproth, B, Jia, W, Whittaker, J, De Meyts, P, Nakagawa, S.H, Steiner, D.F, Katsoyannis, P.G, Weiss, M.A. | 登録日 | 2007-08-31 | 公開日 | 2007-10-16 | 最終更新日 | 2021-10-20 | 実験手法 | SOLUTION NMR | 主引用文献 | The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE. J.Biol.Chem., 282, 2007
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2JUV
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![BU of 2juv by Molmil](/molmil-images/mine/2juv) | AbaA3-DKP-insulin | 分子名称: | Insulin A chain, Insulin B chain | 著者 | Huang, K, Chan, S, Hua, Q, Chu, Y, Wang, R, Klaproth, B, Jia, W, Whittaker, J, De Meyts, P, Nakagawa, S.H, Steiner, D.F, Katsoyannis, P.G, Weiss, M.A. | 登録日 | 2007-09-05 | 公開日 | 2007-10-16 | 最終更新日 | 2021-10-20 | 実験手法 | SOLUTION NMR | 主引用文献 | The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE. J.Biol.Chem., 282, 2007
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5ZKH
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1D62
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1D0H
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![BU of 1d0h by Molmil](/molmil-images/mine/1d0h) | THE HC FRAGMENT OF TETANUS TOXIN COMPLEXED WITH N-ACETYL-GALACTOSAMINE | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, PROTEIN (TETANUS TOXIN HC), SULFATE ION | 著者 | Emsley, P, Fotinou, C, Black, I, Fairweather, N.F, Charles, I.G, Watts, C, Hewitt, E, Isaacs, N.W. | 登録日 | 1999-09-10 | 公開日 | 2000-03-27 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The structures of the H(C) fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside binding. J.Biol.Chem., 275, 2000
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3V9E
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![BU of 3v9e by Molmil](/molmil-images/mine/3v9e) | Structure of the L499M mutant of the laccase from B.aclada | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, GLYCEROL, ... | 著者 | Osipov, E.M, Polyakov, K.M, Tikhonova, T.V, Dorovatovsky, P.V, Ludwig, R, Kittl, R, Shleev, S.V, Popov, V.O. | 登録日 | 2011-12-27 | 公開日 | 2013-01-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Effect of the L499M mutation of the ascomycetous Botrytis aclada laccase on redox potential and catalytic properties. Acta Crystallogr.,Sect.D, 70, 2014
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1D61
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![BU of 1d61 by Molmil](/molmil-images/mine/1d61) | THE STRUCTURE OF THE B-DNA DECAMER C-C-A-A-C-I-T-T-G-G: MONOCLINIC FORM | 分子名称: | CACODYLATE ION, CALCIUM ION, DNA (5'-D(*CP*CP*AP*AP*CP*IP*TP*TP*GP*G)-3') | 著者 | Lipanov, A, Kopka, M.L, Kaczor-Grzeskowiak, M, Quintana, J, Dickerson, R.E. | 登録日 | 1992-02-26 | 公開日 | 1993-04-15 | 最終更新日 | 2023-07-26 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structure of the B-DNA decamer C-C-A-A-C-I-T-T-G-G in two different space groups: conformational flexibility of B-DNA. Biochemistry, 32, 1993
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6ICE
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![BU of 6ice by Molmil](/molmil-images/mine/6ice) | Crystal structure of Hamster MIF | 分子名称: | Macrophage migration inhibitory factor | 著者 | Sundaram, R, Vasudevan, D. | 登録日 | 2018-09-05 | 公開日 | 2019-09-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Macrophage migration inhibitory factor of Syrian golden hamster shares structural and functional similarity with human counterpart and promotes pancreatic cancer. Sci Rep, 9, 2019
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1FV2
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![BU of 1fv2 by Molmil](/molmil-images/mine/1fv2) | The Hc fragment of tetanus toxin complexed with an analogue of its ganglioside receptor GT1B | 分子名称: | ETHYL-TRIMETHYL-SILANE, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-beta-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, PHOSPHATE ION, ... | 著者 | Fotinou, C, Emsley, P, Black, I, Ando, H, Ishida, H, Kiso, M, Sinha, K.A, Fairweather, N.F, Isaacs, N.W. | 登録日 | 2000-09-18 | 公開日 | 2001-09-05 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin. J.Biol.Chem., 276, 2001
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2HZC
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3NUL
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![BU of 3nul by Molmil](/molmil-images/mine/3nul) | Profilin I from Arabidopsis thaliana | 分子名称: | GLYCEROL, PROFILIN I, SULFATE ION | 著者 | Thorn, K, Christensen, H.E.M, Shigeta, R, Huddler, D, Chua, N.-H, Shalaby, L, Lindberg, U, Schutt, C.E. | 登録日 | 1996-11-27 | 公開日 | 1997-12-03 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The crystal structure of a major allergen from plants. Structure, 5, 1997
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4KHP
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![BU of 4khp by Molmil](/molmil-images/mine/4khp) | Structure of the Thermus thermophilus 30S ribosomal subunit in complex with de-6-MSA-pactamycin | 分子名称: | 16S Ribosomal RNA, 30S Ribosomal protein S10, 30S Ribosomal protein S11, ... | 著者 | Tourigny, D.S, Fernandez, I.S, Kelley, A.C, Ramakrishnan, V. | 登録日 | 2013-05-01 | 公開日 | 2013-06-05 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystal Structure of a Bioactive Pactamycin Analog Bound to the 30S Ribosomal Subunit. J.Mol.Biol., 425, 2013
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2KQT
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![BU of 2kqt by Molmil](/molmil-images/mine/2kqt) | Solid-state NMR structure of the M2 transmembrane peptide of the influenza A virus in DMPC lipid bilayers bound to deuterated amantadine | 分子名称: | (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, M2 protein | 著者 | Cady, S.D, Schmidt-Rohr, K, Wang, J, Soto, C.S, DeGrado, W.F, Hong, M. | 登録日 | 2009-11-18 | 公開日 | 2010-02-09 | 最終更新日 | 2024-05-08 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers Nature, 463, 2010
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4M51
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![BU of 4m51 by Molmil](/molmil-images/mine/4m51) | Crystal structure of amidohydrolase nis_0429 (ser145ala mutant) from nitratiruptor sp. sb155-2 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Amidohydrolase family protein, BENZOIC ACID, ... | 著者 | Patskovsky, Y, Toro, R, Gobble, A, Raushel, F.M, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2013-08-07 | 公開日 | 2013-09-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | 主引用文献 | Deamination of 6-aminodeoxyfutalosine in menaquinone biosynthesis by distantly related enzymes. Biochemistry, 52, 2013
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4DBZ
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4DC0
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1DFQ
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![BU of 1dfq by Molmil](/molmil-images/mine/1dfq) | THE HC FRAGMENT OF TETANUS TOXIN COMPLEXED WITH SIALIC ACID | 分子名称: | N-acetyl-beta-neuraminic acid, TETANUS TOXIN HC | 著者 | Emsley, P, Fotinou, C, Black, I, Fairweather, N.F, Charles, I.G, Watts, C, Hewitt, E, Isaacs, N.W. | 登録日 | 1999-11-20 | 公開日 | 2000-03-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The structures of the H(C) fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside binding. J.Biol.Chem., 275, 2000
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