6CML
| Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 2093) | 分子名称: | 1-[(5-chloro-1H-imidazo[4,5-b]pyridin-2-yl)methyl]-4-[(2-chloro-4-methoxyphenyl)methyl]-3-ethyl-1,3-dihydro-2H-imidazol-2-one, GLYCEROL, METHIONINE, ... | 著者 | Barros-Alvarez, X, Hol, W.G.J. | 登録日 | 2018-03-05 | 公開日 | 2019-03-13 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure-guided discovery of selective methionyl-tRNA synthetase inhibitors with potent activity against Trypanosoma brucei Rsc Med Chem, 11, 2020
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6BQM
| Secreted serine protease VesC from Vibrio cholerae | 分子名称: | serine protease VesC | 著者 | Park, Y.J, Korotkov, K.V, Delarosa, J.R, Turley, S, DiMaio, F, Hol, W.G.J. | 登録日 | 2017-11-28 | 公開日 | 2018-11-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Suppressor Mutations in Type II Secretion Mutants of Vibrio cholerae: Inactivation of the VesC Protease. Msphere, 5, 2020
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5USF
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5V49
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2BP2
| THE STRUCTURE OF BOVINE PANCREATIC PROPHOSPHOLIPASE A2 AT 3.0 ANGSTROMS RESOLUTION | 分子名称: | PHOSPHOLIPASE A2 | 著者 | Dijkstra, B.W, Vannes, G.J.H, Kalk, K.H, Brandenburg, N.P, Hol, W.G.J, Drenth, J. | 登録日 | 1981-06-05 | 公開日 | 1981-07-16 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The Structure of Bovine Pancreatic Prophospholipase A2 at 3.0 Angstroms Resolution Acta Crystallogr.,Sect.B, 38, 1982
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1X6O
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1XQ9
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1XIQ
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1XO7
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2BH1
| X-ray structure of the general secretion pathway complex of the N- terminal domain of EpsE and the cytosolic domain of EpsL of Vibrio cholerae | 分子名称: | CALCIUM ION, GENERAL SECRETION PATHWAY PROTEIN E,, GENERAL SECRETION PATHWAY PROTEIN L | 著者 | Abendroth, J, Murphy, P.M, Mushtaq, A, Bagdasarian, M, Sandkvist, M, Hol, W.G.J. | 登録日 | 2005-01-06 | 公開日 | 2005-05-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The X-Ray Structure of the Type II Secretion System Complex Formed by the N-Terminal Domain of Epse and the Cytoplasmic Domain of Epsl of Vibrio Cholerae J.Mol.Biol., 348, 2005
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1YJ8
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1W97
| cyto-EpsL: the cytoplasmic domain of EpsL, an inner membrane component of the type II secretion system of Vibrio cholerae | 分子名称: | TYPE II SECRETION SYSTEM PROTEIN L | 著者 | Abendroth, J, Bagdasarian, M, Sansdkvist, M, Hol, W.G.J. | 登録日 | 2004-10-06 | 公開日 | 2004-11-30 | 最終更新日 | 2019-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The Structure of the Cytoplasmic Domain of Epsl, an Inner Membrane Component of the Type II Secretion System of Vibrio Cholerae: An Unusual Member of the Actin-Like ATPase Superfamily J.Mol.Biol., 344, 2004
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1XQ7
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1XTD
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1XTP
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2B94
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1Y13
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1Y1X
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2B30
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1Y63
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1ZLJ
| Crystal Structure of the Mycobacterium tuberculosis Hypoxic Response Regulator DosR C-terminal Domain | 分子名称: | Dormancy Survival Regulator | 著者 | Wisedchaisri, G, Wu, M, Rice, A.E, Roberts, D.M, Sherman, D.R, Hol, W.G.J. | 登録日 | 2005-05-06 | 公開日 | 2006-01-31 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of Mycobacterium tuberculosis DosR and DosR-DNA complex involved in gene activation during adaptation to hypoxic latency. J.Mol.Biol., 354, 2005
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1XUP
| ENTEROCOCCUS CASSELIFLAVUS GLYCEROL KINASE COMPLEXED WITH GLYCEROL | 分子名称: | GLYCEROL, Glycerol kinase | 著者 | Yeh, J.I, Charrier, V, Paulo, J, Hou, L, Darbon, E, Hol, W.G.J, Deutscher, J. | 登録日 | 2004-10-26 | 公開日 | 2004-12-14 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structures of Enterococcal Glycerol Kinase in the Absence and Presence of Glycerol: Correlation of Conformation to Substrate Binding and a Mechanism of Activation by Phosphorylation Biochemistry, 43, 2004
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1ZLK
| Crystal Structure of the Mycobacterium tuberculosis Hypoxic Response Regulator DosR C-terminal Domain-DNA Complex | 分子名称: | 5'-D(*CP*GP*TP*GP*GP*CP*CP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*AP*CP*TP*TP*TP*AP*GP*TP*CP*CP*CP*CP*AP*AP*AP*GP*CP*GP*CP*GP*GP*GP*CP*CP*AP*T)-3', 5'-D(*GP*GP*CP*CP*CP*GP*CP*GP*CP*TP*TP*TP*GP*GP*GP*GP*AP*CP*TP*AP*AP*AP*GP*TP*CP*CP*CP*TP*AP*AP*CP*CP*CP*TP*GP*GP*CP*CP*AP*CP*GP*AP*T)-3', Dormancy Survival Regulator | 著者 | Wisedchaisri, G, Wu, M, Rice, A.E, Roberts, D.M, Sherman, D.R, Hol, W.G.J. | 登録日 | 2005-05-06 | 公開日 | 2006-01-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structures of Mycobacterium tuberculosis DosR and DosR-DNA complex involved in gene activation during adaptation to hypoxic latency. J.Mol.Biol., 354, 2005
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2A0K
| Crystal structure of Nucleoside 2-deoxyribosyltransferase from Trypanosoma brucei at 1.8 A resolution | 分子名称: | GLYCEROL, Nucleoside 2-deoxyribosyltransferase, SULFATE ION | 著者 | Bosch, J, Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) | 登録日 | 2005-06-16 | 公開日 | 2005-07-26 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase. J.Med.Chem., 49, 2006
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2A0U
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