7TJ0
 
 | | Crystal structure of SARS-CoV-2 3CL in complex with inhibitor SL-4-241 | | 分子名称: | (1S,2S)-2-({N-[(benzyloxy)carbonyl]-3-cyclohexyl-L-alanyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase nsp5, ACETATE ION | | 著者 | Forouhar, F, Liu, H, Iketani, S, Zack, A, Khanizeman, N, Bednarova, E, Fowler, B, Hong, S.J, Mohri, H, Nair, M.S, Huang, Y, Tay, N.E.S, Lee, S, Karan, C, Resnick, S.J, Quinn, C, Li, W, Shion, H, Jurtschenko, C, Lauber, M.A, McDonald, T, Stokes, M, Hurst, B, Rovis, T, Chavez, A, Ho, D.D, Stockwell, B.R. | | 登録日 | 2022-01-14 | | 公開日 | 2022-05-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19.
Nat Commun, 13, 2022
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5E26
 | | Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | | 著者 | DONG, A, LOPPNAU, P, RAVICHANDRAN, M, CHENG, C, TEMPEL, W, SEITOVA, A, HUTCHINSON, A, HONG, B.S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, Structural Genomics Consortium (SGC) | | 登録日 | 2015-09-30 | | 公開日 | 2015-10-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate
to be published
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1FG9
 | | 3:1 COMPLEX OF INTERFERON-GAMMA RECEPTOR WITH INTERFERON-GAMMA DIMER | | 分子名称: | INTERFERON GAMMA, INTERFERON-GAMMA RECEPTOR ALPHA CHAIN | | 著者 | Thiel, D.J, le Du, M.-H, Walter, R.L, D'Arcy, A, Chene, C, Fountoulakis, M, Garotta, G, Winkler, F.K, Ealick, S.E. | | 登録日 | 2000-07-28 | | 公開日 | 2000-08-11 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Observation of an unexpected third receptor molecule in the crystal structure of human interferon-gamma receptor complex.
Structure Fold.Des., 8, 2000
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5BN5
 | | Structural basis for a unique ATP synthase core complex from Nanoarcheaum equitans | | 分子名称: | NEQ263, SULFATE ION, V-type ATP synthase alpha chain | | 著者 | Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J. | | 登録日 | 2015-05-25 | | 公開日 | 2015-09-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.997 Å) | | 主引用文献 | Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans
J.Biol.Chem., 290, 2015
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5BN3
 | | Structure of a unique ATP synthase NeqA-NeqB in complex with ADP from Nanoarcheaum equitans | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | | 著者 | Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J. | | 登録日 | 2015-05-25 | | 公開日 | 2015-09-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans
J.Biol.Chem., 290, 2015
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5BN4
 | | Structure of a unique ATP synthase NeqA-NeqB in complex with ANP from Nanoarcheaum equitans | | 分子名称: | MAGNESIUM ION, NEQ263, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J. | | 登録日 | 2015-05-25 | | 公開日 | 2015-09-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.699 Å) | | 主引用文献 | Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans
J.Biol.Chem., 290, 2015
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5BO5
 | | Structure of a unique ATP synthase subunit NeqB from Nanoarcheaum equitans | | 分子名称: | MAGNESIUM ION, NEQ263, SULFATE ION | | 著者 | Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J. | | 登録日 | 2015-05-27 | | 公開日 | 2015-09-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.808 Å) | | 主引用文献 | Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans
J.Biol.Chem., 290, 2015
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8GWR
 | | Near full length Kidney type Glutaminase in complex with 2,2-Dimethyl-2,3-Dihydrobenzo[a] Phenanthridin-4(1H)-one (DDP) | | 分子名称: | 2,2-dimethyl-1,3-dihydrobenzo[a]phenanthridin-4-one, Glutaminase kidney isoform, mitochondrial | | 著者 | Shankar, S, Jobichen, C, Sivaraman, J. | | 登録日 | 2022-09-17 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | | 主引用文献 | A novel allosteric site employs a conserved inhibition mechanism in human kidney-type glutaminase.
Febs J., 290, 2023
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3WXX
 | | Crystal Structure of a T3SS complex from Aeromonas hydrophila | | 分子名称: | AcrH, AopB, MAGNESIUM ION | | 著者 | Nguyen, V.S, Jobichen, C, Sivaraman, J, Henry, Y.K.M. | | 登録日 | 2014-08-12 | | 公開日 | 2015-10-14 | | 最終更新日 | 2015-11-11 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of AcrH-AopB Chaperone-Translocator Complex Reveals a Role for Membrane Hairpins in Type III Secretion System Translocon Assembly
Structure, 23, 2015
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5OQV
 | | Near-atomic resolution fibril structure of complete amyloid-beta(1-42) by cryo-EM | | 分子名称: | Amyloid beta A4 protein | | 著者 | Gremer, L, Schoelzel, D, Schenk, C, Reinartz, E, Labahn, J, Ravelli, R, Tusche, M, Lopez-Iglesias, C, Hoyer, W, Heise, H, Willbold, D, Schroeder, G.F. | | 登録日 | 2017-08-14 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Fibril structure of amyloid-beta (1-42) by cryo-electron microscopy.
Science, 358, 2017
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1RO2
 | | Bifunctional DNA primase/polymerase domain of ORF904 from the archaeal plasmid pRN1- Triple mutant F50M/L107M/L110M manganese soak | | 分子名称: | MANGANESE (II) ION, ZINC ION, hypothetical protein ORF904 | | 著者 | Lipps, G, Weinzierl, A.O, von Scheven, G, Buchen, C, Cramer, P. | | 登録日 | 2003-12-01 | | 公開日 | 2004-01-27 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of a bifunctional DNA primase-polymerase
Nat.Struct.Mol.Biol., 11, 2004
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1RNI
 | | Bifunctional DNA primase/polymerase domain of ORF904 from the archaeal plasmid pRN1 | | 分子名称: | ORF904, ZINC ION | | 著者 | Lipps, G, Weinzierl, A.O, von Scheven, G, Buchen, C, Cramer, P. | | 登録日 | 2003-12-01 | | 公開日 | 2004-01-27 | | 最終更新日 | 2011-11-16 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structure of a bifunctional DNA primase-polymerase
Nat.Struct.Mol.Biol., 11, 2004
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1RO0
 | | Bifunctional DNA primase/polymerase domain of ORF904 from the archaeal plasmid pRN1- Triple mutant F50M/L107M/L110M SeMet remote | | 分子名称: | ORF904, ZINC ION | | 著者 | Lipps, G, Weinzierl, A.O, von Scheven, G, Buchen, C, Cramer, P. | | 登録日 | 2003-12-01 | | 公開日 | 2004-01-27 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of a bifunctional DNA primase-polymerase
Nat.Struct.Mol.Biol., 11, 2004
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4KT5
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6GHO
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6ST7
 | | Crystal Structure of Domain Swapped Trp Repressor V58I Variant with bound L-trp | | 分子名称: | ISOPROPYL ALCOHOL, TRYPTOPHAN, Trp operon repressor | | 著者 | Sprenger, J, Lawson, C.L, Carey, J, Drouard, F, von Wachenfeldt, C, Schulz, A, Linse, S, Lo Leggio, L. | | 登録日 | 2019-09-10 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Crystal structures of Val58Ile tryptophan repressor in a domain-swapped array in the presence and absence of L-tryptophan.
Acta Crystallogr.,Sect.F, 77, 2021
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8HBC
 | | Crystal structure of the CysR-CTLD3 fragment of human DEC205 | | 分子名称: | Lymphocyte antigen 75 | | 著者 | Kong, D, Yu, B, Hu, Z, Cheng, C, Cao, L, He, Y. | | 登録日 | 2022-10-28 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Interaction of human dendritic cell receptor DEC205/CD205 with keratins.
J.Biol.Chem., 300, 2024
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6GHB
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6ST6
 | | Crystal Structure of Domain Swapped Trp Repressor V58I Variant | | 分子名称: | ISOPROPYL ALCOHOL, Trp operon repressor | | 著者 | Sprenger, J, Lawson, C.L, Carey, J, Drouard, F, von Wachenfeldt, C, Schulz, A, Linse, S, Lo Leggio, L. | | 登録日 | 2019-09-10 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal structures of Val58Ile tryptophan repressor in a domain-swapped array in the presence and absence of L-tryptophan.
Acta Crystallogr.,Sect.F, 77, 2021
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6S9L
 | | Designed Armadillo Repeat protein Lock1 bound to (KR)4KLSF target | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, KR4KLSF Lock1, LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG-LYS-LEU-SER-PHE | | 著者 | Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A. | | 登録日 | 2019-07-15 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.
Acs Chem.Biol., 15, 2020
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6S9N
 | | Designed Armadillo Repeat protein Lock2 fused to target peptide KRKRKAKLSF | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Lock2_KRKRKAKLSF | | 著者 | Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A. | | 登録日 | 2019-07-15 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.
Acs Chem.Biol., 15, 2020
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6S9O
 | | Designed Armadillo Repeat protein internal Lock1 fused to target peptide KRKRKLKFKR | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, designed Armadillo repeat protein with internal Lock1 fused to target peptide KRKRKLKFKR | | 著者 | Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A. | | 登録日 | 2019-07-15 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | | 主引用文献 | Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.
Acs Chem.Biol., 15, 2020
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6S9P
 | | Designed Armadillo Repeat protein internal Lock2 fused to target peptide KRKAKITWKR | | 分子名称: | 1,2-ETHANEDIOL, internal Lock2 fused to target peptide KRKAKITWKR | | 著者 | Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A. | | 登録日 | 2019-07-15 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.
Acs Chem.Biol., 15, 2020
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6S9M
 | | Designed Armadillo Repeat protein Lock2 fused to target peptide KRKRKAKITW | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Lock2_KRKRKAKITW, ... | | 著者 | Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A. | | 登録日 | 2019-07-15 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.
Acs Chem.Biol., 15, 2020
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4NQF
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