3T2F
 
 | | Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, soaked with EDTA and DHAP | | 分子名称: | Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION | | 著者 | Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O. | | 登録日 | 2011-07-22 | | 公開日 | 2011-10-26 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase.
Nature, 478, 2011
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3T2E
 | | Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, F6P-bound form | | 分子名称: | FRUCTOSE -6-PHOSPHATE, Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION | | 著者 | Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O. | | 登録日 | 2011-07-22 | | 公開日 | 2011-10-26 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase.
Nature, 478, 2011
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3T2B
 | | Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, ligand free | | 分子名称: | Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION | | 著者 | Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O. | | 登録日 | 2011-07-22 | | 公開日 | 2011-10-26 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase.
Nature, 478, 2011
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3TA2
 | | A. fulgidus GlnK3, MgATP/2-OG complex | | 分子名称: | 2-OXOGLUTARIC ACID, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Maier, S, Schleberger, P, Lue, W, Wacker, T, Pflueger, T, Litz, C, Andrade, S.L.A. | | 登録日 | 2011-08-03 | | 公開日 | 2011-10-26 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Mechanism of disruption of the Amt-GlnK complex by P(II)-mediated sensing of 2-oxoglutarate.
Plos One, 6, 2011
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5IMO
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5XP0
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8Q7O
 | | Crystal structure of the FZD3 cysteine-rich domain in complex with a nanobody (14478) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, DIMETHYL SULFOXIDE, ... | | 著者 | Hillier, J.S, Zhao, Y, Malinauskas, T, Jones, E.Y. | | 登録日 | 2023-08-16 | | 公開日 | 2024-08-28 | | 最終更新日 | 2024-09-04 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Structural insights into Frizzled3 through nanobody modulators.
Nat Commun, 15, 2024
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8QW4
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5IMK
 | | Nanobody targeting human Vsig4 in Spacegroup C2 | | 分子名称: | Nanobody, V-set and immunoglobulin domain-containing protein 4 | | 著者 | Wen, Y. | | 登録日 | 2016-03-06 | | 公開日 | 2017-01-11 | | 最終更新日 | 2017-07-05 | | 実験手法 | X-RAY DIFFRACTION (1.227 Å) | | 主引用文献 | Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity
Immunobiology, 222, 2017
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5IML
 | | Nanobody targeting human Vsig4 in Spacegroup P212121 | | 分子名称: | Nanobody, V-set and immunoglobulin domain-containing protein 4 | | 著者 | Wen, Y. | | 登録日 | 2016-03-06 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural evaluation of a nanobody targeting complement receptor Vsig4 and its cross reactivity
Immunobiology, 222, 2017
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5IMM
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6O2Z
 | | Crystal structure of IDH1 R132H mutant in complex with compound 32 | | 分子名称: | 6-{[(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)methyl]amino}-2-methylpyridine-3-carbonitrile, GLYCEROL, Isocitrate dehydrogenase [NADP] cytoplasmic, ... | | 著者 | Toms, A.V, Lin, J. | | 登録日 | 2019-02-25 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery and Optimization of Quinolinone Derivatives as Potent, Selective, and Orally Bioavailable Mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors.
J.Med.Chem., 62, 2019
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6O2Y
 | | Crystal structure of IDH1 R132H mutant in complex with compound 24 | | 分子名称: | 4-{[(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)methyl]amino}-2-methoxybenzonitrile, BETA-MERCAPTOETHANOL, Isocitrate dehydrogenase [NADP] cytoplasmic, ... | | 著者 | Toms, A.V, Lin, J. | | 登録日 | 2019-02-25 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Discovery and Optimization of Quinolinone Derivatives as Potent, Selective, and Orally Bioavailable Mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors.
J.Med.Chem., 62, 2019
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6PLX
 | | CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, desensitized state | | 分子名称: | GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Yu, J, Zhu, H, Gouaux, E. | | 登録日 | 2019-07-01 | | 公開日 | 2021-01-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
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6PLZ
 | | CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, closed state | | 分子名称: | GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Yu, J, Zhu, H, Gouaux, E. | | 登録日 | 2019-07-01 | | 公開日 | 2021-01-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
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6PLY
 | | CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, open state | | 分子名称: | GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Yu, J, Zhu, H, Gouaux, E. | | 登録日 | 2019-07-01 | | 公開日 | 2021-01-06 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
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6PLR
 | | CryoEM structure of zebra fish alpha-1 glycine receptor bound with glycine in nanodisc, desensitized state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, Glycine receptor subunit alphaZ1, ... | | 著者 | Yu, J, Zhu, H, Gouaux, E. | | 登録日 | 2019-07-01 | | 公開日 | 2021-01-06 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
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6PLT
 | | CryoEM structure of zebra fish alpha-1 glycine receptor bound with taurine in nanodisc, closed state | | 分子名称: | 2-AMINOETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1, ... | | 著者 | Yu, J, Zhu, H, Gouaux, E. | | 登録日 | 2019-07-01 | | 公開日 | 2021-01-06 | | 最終更新日 | 2021-07-21 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
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6PLO
 | | CryoEM structure of zebra fish alpha-1 glycine receptor YGF mutant bound with GABA in SMA,open state | | 分子名称: | GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Yu, J, Zhu, H, Gouaux, E. | | 登録日 | 2019-07-01 | | 公開日 | 2021-01-06 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
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6PLS
 | | CryoEM structure of zebra fish alpha-1 glycine receptor bound with taurine in nanodisc, desensitized state | | 分子名称: | 2-AMINOETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1, ... | | 著者 | Yu, J, Zhu, H, Gouaux, E. | | 登録日 | 2019-07-01 | | 公開日 | 2021-01-06 | | 最終更新日 | 2021-07-21 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
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6PLV
 | | CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in nanodisc, closed state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, ... | | 著者 | Yu, J, Zhu, H, Gouaux, E. | | 登録日 | 2019-07-01 | | 公開日 | 2021-01-06 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
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6PLU
 | | CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in nanodisc, desensitized state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, ... | | 著者 | Yu, J, Zhu, H, Gouaux, E. | | 登録日 | 2019-07-01 | | 公開日 | 2021-01-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
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6PLQ
 | | CryoEM structure of zebra fish alpha-1 glycine receptor YGF mutant bound with GABA in SMA, super-open state | | 分子名称: | GAMMA-AMINO-BUTANOIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Yu, J, Zhu, H, Gouaux, E. | | 登録日 | 2019-07-01 | | 公開日 | 2021-02-10 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
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6PM1
 | | CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, desensitized state | | 分子名称: | 2-AMINOETHANESULFONIC ACID, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Yu, J, Zhu, H, Gouaux, E. | | 登録日 | 2019-07-01 | | 公開日 | 2021-02-10 | | 最終更新日 | 2021-08-25 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
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6PM4
 | | CryoEM structure of zebra fish alpha-1 glycine receptor bound with Glycine in SMA, super-open state | | 分子名称: | GLYCINE, Glycine receptor subunit alphaZ1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Yu, J, Zhu, H, Gouaux, E. | | 登録日 | 2019-07-01 | | 公開日 | 2021-02-10 | | 最終更新日 | 2021-08-25 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
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