2RGI
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2RPK
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![BU of 2rpk by Molmil](/molmil-images/mine/2rpk) | Solution Structure of Domain II of the Positive Polarity CCHMVD Hammerhead Ribozyme | 分子名称: | RNA (5'-R(*GP*GP*GP*AP*UP*CP*CP*AP*UP*GP*AP*CP*AP*GP*GP*AP*UP*CP*CP*C)-3') | 著者 | Gallego, J, Dufour, D, de la Pena, M, Gago, S, Flores, R. | 登録日 | 2008-05-28 | 公開日 | 2008-12-30 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure-function analysis of the ribozymes of chrysanthemum chlorotic mottle viroid: a loop-loop interaction motif conserved in most natural hammerheads Nucleic Acids Res., 37, 2009
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2RT5
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2RN7
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![BU of 2rn7 by Molmil](/molmil-images/mine/2rn7) | NMR solution structure of TnpE protein from Shigella flexneri. Northeast Structural Genomics Target SfR125 | 分子名称: | IS629 orfA | 著者 | Ramelot, T.A, Cort, J.R, Semesi, A, Garcia, M, Yee, A.A, Arrowsmith, C.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-12-08 | 公開日 | 2008-01-15 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution structure of TnpE protein from Shigella flexneri. Northeast
Structural Genomics Target SfR125 To be Published
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2ROW
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8FJZ
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![BU of 8fjz by Molmil](/molmil-images/mine/8fjz) | Crystal structure of HPK1 kinase domain T165E,S171E phosphomimetic mutant in complex with 3-{4-[(3R,5S)-3-Amino-5-methylpiperidin-1-yl]-6-chloro-7H-pyrrolo[2,3-d]pyrimidin-5-yl}benzonitrile | 分子名称: | (3P)-3-{4-[(3R,5S)-3-amino-5-methylpiperidin-1-yl]-6-chloro-7H-pyrrolo[2,3-d]pyrimidin-5-yl}benzonitrile, Mitogen-activated protein kinase kinase kinase kinase 1 | 著者 | McTigue, M, Johnson, E, Cronin, C. | 登録日 | 2022-12-20 | 公開日 | 2023-04-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.897 Å) | 主引用文献 | Design and Synthesis of Functionally Active 5-Amino-6-Aryl Pyrrolopyrimidine Inhibitors of Hematopoietic Progenitor Kinase 1. J.Med.Chem., 66, 2023
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8FH4
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![BU of 8fh4 by Molmil](/molmil-images/mine/8fh4) | Crystal structure of HPK1 kinase domain T165E,S171E phosphomimetic mutant in complex with 3-[6-chloro-4-(9-methyl-1-oxa-4,9-diazaspiro[5.5]undec-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile | 分子名称: | (3P)-3-[6-chloro-4-(9-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile, Mitogen-activated protein kinase kinase kinase kinase 1, SULFATE ION | 著者 | McTigue, M, Johnson, E, Cronin, C. | 登録日 | 2022-12-13 | 公開日 | 2023-04-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.827 Å) | 主引用文献 | Design and Synthesis of Functionally Active 5-Amino-6-Aryl Pyrrolopyrimidine Inhibitors of Hematopoietic Progenitor Kinase 1. J.Med.Chem., 66, 2023
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8FKO
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![BU of 8fko by Molmil](/molmil-images/mine/8fko) | Crystal structure of HPK1 kinase domain T165E,S171E phosphomimetic mutant in complex with 3-{4-[(2S,5R)-5-Amino-2-methylpiperidin-1-yl]-6-chloro-7H-pyrrolo[2,3-d]pyrimidin-5-yl}benzonitrile | 分子名称: | (3P)-3-{4-[(2S,5R)-5-amino-2-methylpiperidin-1-yl]-6-chloro-7H-pyrrolo[2,3-d]pyrimidin-5-yl}benzonitrile, Mitogen-activated protein kinase kinase kinase kinase 1 | 著者 | McTigue, M, Johnson, E, Cronin, C. | 登録日 | 2022-12-21 | 公開日 | 2023-04-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.104 Å) | 主引用文献 | Design and Synthesis of Functionally Active 5-Amino-6-Aryl Pyrrolopyrimidine Inhibitors of Hematopoietic Progenitor Kinase 1. J.Med.Chem., 66, 2023
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6LHE
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![BU of 6lhe by Molmil](/molmil-images/mine/6lhe) | Crystal Structure of Gold-bound NDM-1 | 分子名称: | GOLD ION, Metallo-beta-lactamase type 2, SULFATE ION | 著者 | Wang, H, Sun, H, Wang, M. | 登録日 | 2019-12-07 | 公開日 | 2020-09-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.206 Å) | 主引用文献 | Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin. Nat Commun, 11, 2020
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7RZC
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![BU of 7rzc by Molmil](/molmil-images/mine/7rzc) | Papain-Like Protease of SARS CoV-2 in complex with Jun9-84-3 inhibitor | 分子名称: | (1R)-N-[(1H-indol-3-yl)methyl]-N-methyl-1-(naphthalen-1-yl)ethan-1-amine, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | Osipiuk, J, Tesar, C, Endres, M, Wang, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-08-27 | 公開日 | 2021-09-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Papain-Like Protease of SARS CoV-2 in complex with Jun9-84-3 inhibitor To be Published
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6L9F
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6LB0
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6MDD
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6LBU
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![BU of 6lbu by Molmil](/molmil-images/mine/6lbu) | Crystal structure of yeast Stn1 and Ten1 | 分子名称: | KLLA0C11825p, KLLA0E09417p | 著者 | Ge, Y, Wu, Z, Wu, J, Lei, M. | 登録日 | 2019-11-14 | 公開日 | 2020-07-15 | 最終更新日 | 2020-08-19 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural insights into telomere protection and homeostasis regulation by yeast CST complex. Nat.Struct.Mol.Biol., 27, 2020
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6KVD
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![BU of 6kvd by Molmil](/molmil-images/mine/6kvd) | Crystal structure of human nucleosome containing H2A.J | 分子名称: | CHLORIDE ION, DNA (146-MER), Histone H2A.J, ... | 著者 | Tanaka, H, Koyama, M, Sato, S, Kujirai, T, Kurumizaka, H. | 登録日 | 2019-09-04 | 公開日 | 2019-12-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Biochemical and structural analyses of the nucleosome containing human histone H2A.J. J.Biochem., 167, 2020
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7RZP
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![BU of 7rzp by Molmil](/molmil-images/mine/7rzp) | Crystal structure of putative NAD(P)H-flavin oxidoreductase from Haemophilus influenzae R2866 | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, Dihydropteridine reductase, ... | 著者 | Maltseva, N, Kim, Y, Endres, M, Crofts, T, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-08-27 | 公開日 | 2021-09-29 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Functional and Structural Characterization of Diverse NfsB Chloramphenicol Reductase Enzymes from Human Pathogens. Microbiol Spectr, 10, 2022
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7S6P
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![BU of 7s6p by Molmil](/molmil-images/mine/7s6p) | The crystal structure of human ISG15 | 分子名称: | Ubiquitin-like protein ISG15 | 著者 | Osipiuk, J, Tesar, C, Jedrzejczak, R, Endres, M, Wydorski, P, Joachimiak, L, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-09-14 | 公開日 | 2021-09-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin. Nat Commun, 14, 2023
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7SDR
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![BU of 7sdr by Molmil](/molmil-images/mine/7sdr) | Papain-Like Protease of SARS CoV-2 in Complex with Jun9-72-2 Inhibitor | 分子名称: | 1,2-ETHANEDIOL, 4-({methyl[(1R)-1-(naphthalen-1-yl)ethyl]amino}methyl)phenol, CHLORIDE ION, ... | 著者 | Osipiuk, J, Tesar, C, Endres, M, Wang, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-09-29 | 公開日 | 2021-10-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Papain-Like Protease of SARS CoV-2 in Complex with Jun9-72-2 Inhibitor To be Published
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7S0N
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![BU of 7s0n by Molmil](/molmil-images/mine/7s0n) | Structure of MS3494 from Mycobacterium Smegmatis determined by Solution NMR | 分子名称: | Secreted protein | 著者 | Kent, J.E, Tian, Y, Shin, K, Zhang, L, Niederweis, M, Marassi, F.M. | 登録日 | 2021-08-30 | 公開日 | 2021-10-06 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of MS3494 from Mycobacterium Smegmatis To Be Published
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7S14
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![BU of 7s14 by Molmil](/molmil-images/mine/7s14) | Crystal structure of putative NAD(P)H-flavin oxidoreductase from Haemophilus influenzae 86-028NP | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Kim, Y, Maltseva, N, Endres, M, Crofts, T, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-08-31 | 公開日 | 2021-10-06 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Functional and Structural Characterization of Diverse NfsB Chloramphenicol Reductase Enzymes from Human Pathogens. Microbiol Spectr, 10, 2022
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7RZL
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![BU of 7rzl by Molmil](/molmil-images/mine/7rzl) | Crystal structure of putative NAD(P)H-flavin oxidoreductase from Haemophilus influenzae R2846 in complex with 4-nitrophenol | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN MONONUCLEOTIDE, ... | 著者 | Maltseva, N, Kim, Y, Endres, M, Crofts, T, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-08-27 | 公開日 | 2021-09-29 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Functional and Structural Characterization of Diverse NfsB Chloramphenicol Reductase Enzymes from Human Pathogens. Microbiol Spectr, 10, 2022
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6L0Q
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![BU of 6l0q by Molmil](/molmil-images/mine/6l0q) | Crystal Structure of the O-Phosphoserine Sulfhydrylase from Aeropyrum pernix Complexed with O-Phosphoserine | 分子名称: | (2S)-2-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-phosphonooxy-propanoic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, Protein CysO | 著者 | Nakabayashi, M, Takeda, E, Ishikawa, K, Nakamura, T. | 登録日 | 2019-09-26 | 公開日 | 2020-09-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Identification of amino acid residues important for recognition of O-phospho-l-serine substrates by cysteine synthase. J.Biosci.Bioeng., 131, 2021
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8UO9
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![BU of 8uo9 by Molmil](/molmil-images/mine/8uo9) | Structure of synaptic vesicle protein 2A in complex with a nanobody | 分子名称: | (4R)-1-{[(4S)-2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]methyl}-4-(4,4,4-trifluorobutyl)pyrrolidin-2-one, 1,2-DIDECANOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE], 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Mittal, A, Martin, M.F, Levin, E, Adams, C, Yang, M, Ledecq, M, Horanyi, P.S, Coleman, J.A. | 登録日 | 2023-10-19 | 公開日 | 2024-05-22 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structures of synaptic vesicle protein 2A and 2B bound to anticonvulsants. Nat.Struct.Mol.Biol., 2024
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7S2N
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6L2N
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![BU of 6l2n by Molmil](/molmil-images/mine/6l2n) | Crystal structure of the R.PabI(Y68F-K154A)-dsDNA(GTAC-3bp-GTAC) complex | 分子名称: | DNA (5'-D(*TP*CP*AP*GP*CP*AP*GP*TP*AP*CP*TP*AP*AP*GP*TP*AP*CP*TP*GP*CP*TP*GP*A)-3'), RE_R_Pab1 domain-containing protein | 著者 | Miyazono, K, Wang, D, Ito, T, Tanokura, M. | 登録日 | 2019-10-05 | 公開日 | 2020-03-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Distortion of double-stranded DNA structure by the binding of the restriction DNA glycosylase R.PabI. Nucleic Acids Res., 48, 2020
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