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1P10
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BU of 1p10 by Molmil
STRUCTURAL PLASTICITY AS A DETERMINANT OF ENZYME SPECIFICITY. CREATING BROADLY SPECIFIC PROTEASES
分子名称: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-VALINE BORONIC ACID INHIBITOR, SULFATE ION
著者Bone, R, Agard, D.A.
登録日1989-04-24
公開日1990-04-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural plasticity broadens the specificity of an engineered protease.
Nature, 339, 1989
1P09
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STRUCTURAL PLASTICITY AS A DETERMINANT OF ENZYME SPECIFICITY. CREATING BROADLY SPECIFIC PROTEASES
分子名称: ALPHA-LYTIC PROTEASE, SULFATE ION
著者Bone, R, Agard, D.A.
登録日1989-04-24
公開日1990-04-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural plasticity broadens the specificity of an engineered protease.
Nature, 339, 1989
1P06
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BU of 1p06 by Molmil
STRUCTURE ANALYSIS OF SPECIFICITY. ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGUES OF REACTION INTERMEDIATES
分子名称: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
著者Bone, R, Agard, D.A.
登録日1989-04-24
公開日1990-04-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates.
Biochemistry, 28, 1989
1AVF
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BU of 1avf by Molmil
ACTIVATION INTERMEDIATE 2 OF HUMAN GASTRICSIN FROM HUMAN STOMACH
分子名称: GASTRICSIN, SODIUM ION
著者Khan, A.R, Cherney, M.M, Tarasova, N.I, James, M.N.G.
登録日1997-09-16
公開日1998-02-25
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural characterization of activation 'intermediate 2' on the pathway to human gastricsin.
Nat.Struct.Biol., 4, 1997
1EUD
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BU of 1eud by Molmil
CRYSTAL STRUCTURE OF PHOSPHORYLATED PIG HEART, GTP-SPECIFIC SUCCINYL-COA SYNTHETASE
分子名称: SUCCINYL-COA SYNTHETASE, ALPHA CHAIN, BETA CHAIN, ...
著者Fraser, M.E, James, M.N.G, Bridger, W.A, Wolodko, W.T.
登録日2000-04-14
公開日2000-07-27
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Phosphorylated and dephosphorylated structures of pig heart, GTP-specific succinyl-CoA synthetase.
J.Mol.Biol., 299, 2000
1EAI
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COMPLEX OF ASCARIS CHYMOTRPSIN/ELASTASE INHIBITOR WITH PORCINE ELASTASE
分子名称: PROTEIN (CHYMOTRYPSIN/ELASTASE ISOINHIBITOR 1), PROTEIN (ELASTASE)
著者Huang, K, Strynadka, N.C.J, Bernard, V.D, Peanasky, R.J, James, M.N.G.
登録日1999-03-25
公開日1999-04-05
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The molecular structure of the complex of Ascaris chymotrypsin/elastase inhibitor with porcine elastase.
Structure, 2, 1994
1EUC
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CRYSTAL STRUCTURE OF DEPHOSPHORYLATED PIG HEART, GTP-SPECIFIC SUCCINYL-COA SYNTHETASE
分子名称: PHOSPHATE ION, SUCCINYL-COA SYNTHETASE, ALPHA CHAIN, ...
著者Fraser, M.E, James, M.N.G, Bridger, W.A, Wolodko, W.T.
登録日2000-04-14
公開日2000-07-27
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Phosphorylated and dephosphorylated structures of pig heart, GTP-specific succinyl-CoA synthetase.
J.Mol.Biol., 299, 2000
1PUC
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P13SUC1 IN A STRAND-EXCHANGED DIMER
分子名称: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, P13SUC1
著者Khazanovich, N, Bateman, K.S, Chernaia, M, Michalak, M, James, M.N.G.
登録日1995-12-08
公開日1996-04-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the yeast cell-cycle control protein, p13suc1, in a strand-exchanged dimer.
Structure, 4, 1996
1QS8
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Crystal structure of the P. vivax aspartic proteinase plasmepsin complexed with the inhibitor pepstatin A
分子名称: ACETATE ION, PEPSTATIN A, PLASMEPSIN
著者Khazanovich Bernstein, N, Cherney, M.M, Yowell, C.A, Dame, J.B, James, M.N.G.
登録日1999-06-25
公開日1999-07-07
最終更新日2013-02-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into the activation of P. vivax plasmepsin.
J.Mol.Biol., 329, 2003
1PFZ
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PROPLASMEPSIN II FROM PLASMODIUM FALCIPARUM
分子名称: GLYCEROL, PROPLASMEPSIN II
著者Bernstein, N.K, Cherney, M.M, Loetscher, H, Ridley, R.G, James, M.N.G.
登録日1998-07-07
公開日1999-01-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the novel aspartic proteinase zymogen proplasmepsin II from plasmodium falciparum.
Nat.Struct.Biol., 6, 1999
3ER5
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THE ACTIVE SITE OF ASPARTIC PROTEINASES
分子名称: ENDOTHIAPEPSIN, H-189
著者Bailey, D, Veerapandian, B, Cooper, J, Szelke, M, Blundell, T.L.
登録日1991-01-05
公開日1991-04-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray-crystallographic studies of complexes of pepstatin A and a statine-containing human renin inhibitor with endothiapepsin.
Biochem.J., 289 ( Pt 2), 1993
3CI2
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BU of 3ci2 by Molmil
REFINEMENT OF THE THREE-DIMENSIONAL SOLUTION STRUCTURE OF BARLEY SERINE PROTEINASE INHIBITOR 2 AND COMPARISON WITH THE STRUCTURES IN CRYSTALS
分子名称: CHYMOTRYPSIN INHIBITOR 2
著者Poulsen, F.M.
登録日1991-09-10
公開日1993-10-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Refinement of the three-dimensional solution structure of barley serine proteinase inhibitor 2 and comparison with the structures in crystals.
J.Mol.Biol., 222, 1991
3ER3
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BU of 3er3 by Molmil
The active site of aspartic proteinases
分子名称: 6-ammonio-N-[(2R,4R,5R)-5-{[N-(tert-butoxycarbonyl)-L-phenylalanyl-3-(1H-imidazol-3-ium-4-yl)-L-alanyl]amino}-6-cyclohexyl-4-hydroxy-2-(2-methylpropyl)hexanoyl]-L-norleucylphenylalanine, ENDOTHIAPEPSIN
著者Al-Karadaghi, S, Cooper, J.B, Veerapandian, B, Hoover, D, Blundell, T.L.
登録日1991-01-02
公開日1991-04-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Active Site of Aspartic Proteinases
FEBS Lett., 174, 1984
2ER9
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BU of 2er9 by Molmil
X-RAY STUDIES OF ASPARTIC PROTEINASE-STATINE INHIBITOR COMPLEXES.
分子名称: ENDOTHIAPEPSIN, L363,564
著者Cooper, J.B, Foundling, S.I, Boger, J, Blundell, T.L.
登録日1990-10-20
公開日1991-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-ray studies of aspartic proteinase-statine inhibitor complexes.
Biochemistry, 28, 1989
2ER7
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BU of 2er7 by Molmil
X-RAY ANALYSES OF ASPARTIC PROTEINASES.III. THREE-DIMENSIONAL STRUCTURE OF ENDOTHIAPEPSIN COMPLEXED WITH A TRANSITION-STATE ISOSTERE INHIBITOR OF RENIN AT 1.6 ANGSTROMS RESOLUTION
分子名称: ENDOTHIAPEPSIN, SULFATE ION, TRANSITION-STATE ISOSTERE INHIBITOR OF RENIN
著者Veerapandian, B, Cooper, J.B, Szelke, M, Blundell, T.L.
登録日1990-11-12
公開日1991-01-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献X-ray analyses of aspartic proteinases. III Three-dimensional structure of endothiapepsin complexed with a transition-state isostere inhibitor of renin at 1.6 A resolution.
J.Mol.Biol., 216, 1990
2ER6
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BU of 2er6 by Molmil
The structure of a synthetic pepsin inhibitor complexed with endothiapepsin.
分子名称: ENDOTHIAPEPSIN, H-256 peptide
著者Cooper, J.B, Foundling, S.I, Szelke, M, Blundell, T.L.
登録日1990-10-13
公開日1991-01-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structure of a synthetic pepsin inhibitor complexed with endothiapepsin
Eur.J.Biochem., 169, 1987
2ER0
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BU of 2er0 by Molmil
X-RAY STUDIES OF ASPARTIC PROTEINASE-STATINE INHIBITOR COMPLEXES
分子名称: ENDOTHIAPEPSIN, L364,099
著者Cooper, J.B, Foundling, S.I, Boger, J, Blundell, T.L.
登録日1990-10-20
公開日1991-01-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray studies of aspartic proteinase-statine inhibitor complexes.
Biochemistry, 28, 1989
1RNE
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BU of 1rne by Molmil
THE CRYSTAL STRUCTURE OF RECOMBINANT GLYCOSYLATED HUMAN RENIN ALONE AND IN COMPLEX WITH A TRANSITION STATE ANALOG INHIBITOR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, RENIN, [[[3-(2-METHYL-PROPANE-2-SULFONYL)-1-BENZENYL]-2-PROPYL]-CARBONYL-HISTIDYL]-AMINO-[CYCLOHEXYLMETHYL]-[2-HYDROXY-4-ISOPROPYL]-PENTAN-5-OIC ACID BUTYLAMIDE
著者Gruetter, M.G, Rahuel, J, Priestle, J.P.
登録日1991-12-12
公開日1993-10-31
最終更新日2020-10-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structures of recombinant glycosylated human renin alone and in complex with a transition state analog inhibitor.
J.Struct.Biol., 107, 1991
1SIB
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BU of 1sib by Molmil
REFINED CRYSTAL STRUCTURES OF SUBTILISIN NOVO IN COMPLEX WITH WILD-TYPE AND TWO MUTANT EGLINS. COMPARISON WITH OTHER SERINE PROTEINASE INHIBITOR COMPLEXES
分子名称: CALCIUM ION, EGLIN C, SUBTILISIN NOVO BPN'
著者Gruetter, M.G, Heinz, D.W, Priestle, J.P.
登録日1993-08-02
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Refined crystal structures of subtilisin novo in complex with wild-type and two mutant eglins. Comparison with other serine proteinase inhibitor complexes.
J.Mol.Biol., 217, 1991
1SBN
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BU of 1sbn by Molmil
REFINED CRYSTAL STRUCTURES OF SUBTILISIN NOVO IN COMPLEX WITH WILD-TYPE AND TWO MUTANT EGLINS. COMPARISON WITH OTHER SERINE PROTEINASE INHIBITOR COMPLEXES
分子名称: CALCIUM ION, EGLIN C, SUBTILISIN NOVO BPN'
著者Gruetter, M.G, Heinz, D.W, Priestle, J.P.
登録日1991-12-20
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Refined crystal structures of subtilisin novo in complex with wild-type and two mutant eglins. Comparison with other serine proteinase inhibitor complexes.
J.Mol.Biol., 217, 1991
1H6M
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Covalent glycosyl-enzyme intermediate of hen egg white lysozyme
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-glucopyranose, LYSOZYME C, SODIUM ION
著者Vocadlo, D.J, Davies, G.J, Laine, R, Withers, S.G.
登録日2001-06-19
公開日2001-08-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Catalysis by Hen Egg-White Lysozyme Proceeds Via a Covalent Intermediate
Nature, 412, 2001
1CSE
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BU of 1cse by Molmil
THE HIGH-RESOLUTION X-RAY CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN SUBTILISIN CARLSBERG AND EGLIN C, AN ELASTASE INHIBITOR FROM THE LEECH HIRUDO MEDICINALIS. STRUCTURAL ANALYSIS, SUBTILISIN STRUCTURE AND INTERFACE GEOMETRY
分子名称: CALCIUM ION, EGLIN C, SUBTILISIN CARLSBERG
著者Bode, W.
登録日1988-06-03
公開日1988-07-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The high-resolution X-ray crystal structure of the complex formed between subtilisin Carlsberg and eglin c, an elastase inhibitor from the leech Hirudo medicinalis. Structural analysis, subtilisin structure and interface geometry.
Eur.J.Biochem., 166, 1987
1CQ4
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CI2 MUTANT WITH TETRAGLUTAMINE (MGQQQQGM) REPLACING MET59
分子名称: PROTEIN (SERINE PROTEINASE INHIBITOR 2), SULFATE ION
著者Chen, Y.W, Stott, K.R.
登録日1998-11-17
公開日1998-11-25
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a dimeric chymotrypsin inhibitor 2 mutant containing an inserted glutamine repeat.
Proc.Natl.Acad.Sci.USA, 96, 1999
1COA
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THE EFFECT OF CAVITY CREATING MUTATIONS IN THE HYDROPHOBIC CORE OF CHYMOTRYPSIN INHIBITOR 2
分子名称: CHYMOTRYPSIN INHIBITOR 2
著者Jackson, S.E, Moracci, M, Elmasry, N, Johnson, C.M, Fersht, A.R.
登録日1993-05-14
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Effect of cavity-creating mutations in the hydrophobic core of chymotrypsin inhibitor 2.
Biochemistry, 32, 1993
1ER8
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THE ACTIVE SITE OF ASPARTIC PROTEINASES
分子名称: Endothiapepsin, H-77
著者Hemmings, A.M, Veerapandian, B, Szelke, M, Cooper, J.B, Blundell, T.L.
登録日1989-10-16
公開日1991-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Active Site of Aspartic Proteinases
FEBS Lett., 174, 1984

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