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1BRC
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BU of 1brc by Molmil
RELOCATING A NEGATIVE CHARGE IN THE BINDING POCKET OF TRYPSIN
Descriptor: AMYLOID BETA-PROTEIN PRECURSOR INHIBITOR DOMAIN (APPI), TRYPSIN
Authors:Perona, J.J, Fletterick, R.J.
Deposit date:1992-12-17
Release date:1994-05-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Relocating a negative charge in the binding pocket of trypsin.
J.Mol.Biol., 230, 1993
1GTS
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BU of 1gts by Molmil
STRUCTURAL BASIS FOR TRANSFER RNA AMINOACEYLATION BY ESCHERICHIA COLI GLUTAMINYL-TRNA SYNTHETASE
Descriptor: ADENOSINE MONOPHOSPHATE, PROTEIN (GLUTAMINYL-TRNA SYNTHETASE (E.C.6.1.1.18)), TRNAGLN
Authors:Perona, J.J, Steitz, T.A, Rould, M.A.
Deposit date:1993-09-15
Release date:1995-02-07
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for transfer RNA aminoacylation by Escherichia coli glutaminyl-tRNA synthetase.
Biochemistry, 32, 1993
1BRB
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BU of 1brb by Molmil
CRYSTAL STRUCTURES OF RAT ANIONIC TRYPSIN COMPLEXED WITH THE PROTEIN INHIBITORS APPI AND BPTI
Descriptor: PANCREATIC TRYPSIN INHIBITOR, TRYPSIN
Authors:Perona, J.J, Fletterick, R.J.
Deposit date:1992-12-17
Release date:1994-07-31
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of rat anionic trypsin complexed with the protein inhibitors APPI and BPTI.
J.Mol.Biol., 230, 1993
1BRA
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BU of 1bra by Molmil
RELOCATING A NEGATIVE CHARGE IN THE BINDING POCKET OF TRYPSIN
Descriptor: BENZAMIDINE, CALCIUM ION, TRYPSIN
Authors:Perona, J.J, Mcgrath, M.E, Fletterick, R.J.
Deposit date:1992-12-17
Release date:1994-04-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Relocating a negative charge in the binding pocket of trypsin.
J.Mol.Biol., 230, 1993
1AZ0
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BU of 1az0 by Molmil
ECORV ENDONUCLEASE/DNA COMPLEX
Descriptor: CALCIUM ION, DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), PROTEIN (TYPE II RESTRICTION ENZYME ECORV)
Authors:Perona, J.J, Martin, A.M.
Deposit date:1997-11-24
Release date:1998-06-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational transitions and structural deformability of EcoRV endonuclease revealed by crystallographic analysis.
J.Mol.Biol., 273, 1997
1AZZ
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BU of 1azz by Molmil
FIDDLER CRAB COLLAGENASE COMPLEXED TO ECOTIN
Descriptor: COLLAGENASE, ECOTIN
Authors:Perona, J.J, Fletterick, R.J.
Deposit date:1997-11-24
Release date:1998-02-25
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of an ecotin-collagenase complex suggests a model for recognition and cleavage of the collagen triple helix.
Biochemistry, 36, 1997
1BSS
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BU of 1bss by Molmil
ECORV-T93A/DNA/CA2+
Descriptor: 5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3', CALCIUM ION, ECORV ENDONUCLEASE
Authors:Perona, J.J, Horton, N.C.
Deposit date:1998-08-30
Release date:1998-09-02
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Metal ion-mediated substrate-assisted catalysis in type II restriction endonucleases
Proc.Natl.Acad.Sci.USA, 95, 1998
1BUA
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BU of 1bua by Molmil
STRUCTURAL AND ENERGETIC ORIGINS OF INDIRECT READOUT IN SITE-SPECIFIC DNA CLEAVAGE BY A RESTRICTION ENDONUCLEASE
Descriptor: DNA (5'-D(*AP*AP*AP*GP*AP*CP*IP*TP*CP*TP*T)-3'), ENDONUCLEASE ECORV
Authors:Perona, J.J, Martin, A.M.
Deposit date:1998-09-03
Release date:1998-09-09
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and energetic origins of indirect readout in site-specific DNA cleavage by a restriction endonuclease.
Nat.Struct.Biol., 6, 1999
1BSU
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BU of 1bsu by Molmil
STRUCTURAL AND ENERGETIC ORIGINS OF INDIRECT READOUT IN SITE-SPECIFIC DNA CLEAVAGE BY A RESTRICTION ENDONUCLEASE
Descriptor: CALCIUM ION, DNA (5'-D(*AP*AP*AP*GP*AP*(5CM)P*IP*TP*CP*TP*T)-3'), DNA (5'-D(P*AP*AP*GP*AP*(5CM)P*IP*TP*CP*TP*T)-3'), ...
Authors:Perona, J.J, Martin, A.M.
Deposit date:1998-08-30
Release date:1998-09-09
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and energetic origins of indirect readout in site-specific DNA cleavage by a restriction endonuclease.
Nat.Struct.Biol., 6, 1999
4JXX
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BU of 4jxx by Molmil
Crystal structure of E coli E. coli glutaminyl-tRNA synthetase bound to tRNA(Gln)(CUG) and ATP from novel cryostabilization conditions
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Glutamine--tRNA ligase, RNA (71-MER), ...
Authors:Perona, J.J, Rodriguez-Hernandez, A.
Deposit date:2013-03-28
Release date:2013-05-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Mechanistic Basis for Enhanced Translational Efficiency by 2-Thiouridine at the tRNA Anticodon Wobble Position.
J.Mol.Biol., 425, 2013
4JXZ
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BU of 4jxz by Molmil
Structure of E. coli glutaminyl-tRNA synthetase bound to ATP and a tRNA(Gln) acceptor containing a UUG anticodon
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Glutamine--tRNA ligase, RNA (71-MER), ...
Authors:Perona, J.J, Rodriguez-Hernandez, A.
Deposit date:2013-03-28
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and Mechanistic Basis for Enhanced Translational Efficiency by 2-Thiouridine at the tRNA Anticodon Wobble Position.
J.Mol.Biol., 425, 2013
4JYZ
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BU of 4jyz by Molmil
Crystal structure of E. coli glutaminyl-tRNA synthetase bound to ATP and native tRNA(Gln) containing the cmnm5s2U34 anticodon wobble base
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Glutamine--tRNA ligase, RNA (72-MER), ...
Authors:Perona, J.J, Rodriguez-Hernandez, A.
Deposit date:2013-04-01
Release date:2013-05-29
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and Mechanistic Basis for Enhanced Translational Efficiency by 2-Thiouridine at the tRNA Anticodon Wobble Position.
J.Mol.Biol., 425, 2013
2B0D
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BU of 2b0d by Molmil
EcoRV Restriction Endonuclease/GAATTC/Ca2+
Descriptor: 5'-D(*AP*AP*AP*GP*AP*AP*TP*TP*CP*TP*T)-3', CALCIUM ION, Type II restriction enzyme EcoRV
Authors:Hiller, D.A, Rodriguez, A.M, Perona, J.J.
Deposit date:2005-09-13
Release date:2005-09-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Non-cognate Enzyme-DNA Complex: Structural and Kinetic Analysis of EcoRV Endonuclease Bound to the EcoRI Recognition Site GAATTC
J.Mol.Biol., 354, 2005
2B0E
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BU of 2b0e by Molmil
EcoRV Restriction Endonuclease/GAAUTC/Ca2+
Descriptor: 5'-D(*AP*AP*AP*GP*AP*AP*(DU)P*TP*CP*TP*T)-3', CALCIUM ION, Type II restriction enzyme EcoRV
Authors:Hiller, D.A, Rodriguez, A.M, Perona, J.J.
Deposit date:2005-09-13
Release date:2005-09-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Non-cognate Enzyme-DNA Complex: Structural and Kinetic Analysis of EcoRV Endonuclease Bound to the EcoRI Recognition Site GAATTC
J.Mol.Biol., 354, 2005
1LI7
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BU of 1li7 by Molmil
Crystal Structure of Cysteinyl-tRNA Synthetase with Cysteine Substrate Bound
Descriptor: CYSTEINE, CYSTEINYL-TRNA SYNTHETASE, ZINC ION
Authors:Newberry, K.J, Hou, Y.-M, Perona, J.J.
Deposit date:2002-04-17
Release date:2002-04-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural origins of amino acid selection without editing by cysteinyl-tRNA synthetase
EMBO J., 21, 2002
1LI5
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BU of 1li5 by Molmil
Crystal Structure of Cysteinyl-tRNA Synthetase
Descriptor: CYSTEINYL-TRNA SYNTHETASE, ZINC ION
Authors:Newberry, K.J, Hou, Y.-M, Perona, J.J.
Deposit date:2002-04-17
Release date:2002-04-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural origins of amino acid selection without editing by cysteinyl-tRNA synthetase
EMBO J., 21, 2002
2RD2
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BU of 2rd2 by Molmil
Glutaminyl-tRNA synthetase mutant C229R with bound analog 5'-O-[N-(L-GLUTAMINYL)-SULFAMOYL]ADENOSINE
Descriptor: 5'-O-[N-(L-GLUTAMINYL)-SULFAMOYL]ADENOSINE, Glutamine tRNA, Glutaminyl-tRNA synthetase, ...
Authors:Bullock, T.L, Perona, J.J.
Deposit date:2007-09-20
Release date:2008-01-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A rationally engineered misacylating aminoacyl-tRNA synthetase.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2RE8
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BU of 2re8 by Molmil
Glutaminyl-tRNA synthetase mutant C229R with bound analog 5'-O-[N-(L-GLUTAMYL)-SULFAMOYL]ADENOSINE
Descriptor: Glutamine tRNA, Glutaminyl-tRNA synthetase, O5'-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE, ...
Authors:Bullock, T.L, Perona, J.J.
Deposit date:2007-09-25
Release date:2008-01-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A rationally engineered misacylating aminoacyl-tRNA synthetase.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1GSG
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BU of 1gsg by Molmil
Structure of E.coli glutaminyl-tRNA synthetase complexed with trnagln and ATP at 2.8 Angstroms resolution
Descriptor: GLUTAMINYL-TRNA SYNTHETASE, TRNAGLN
Authors:Rould, M.A, Perona, J.J, Soell, D, Steitz, T.A.
Deposit date:1990-04-03
Release date:1992-02-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of E. coli glutaminyl-tRNA synthetase complexed with tRNA(Gln) and ATP at 2.8 A resolution.
Science, 246, 1989
1ZJW
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BU of 1zjw by Molmil
Glutaminyl-tRNA synthetase complexed to glutamine and 2'deoxy A76 glutamine tRNA
Descriptor: ADENOSINE MONOPHOSPHATE, GLUTAMINE, Glutaminyl-tRNA, ...
Authors:Gruic-Sovulj, I, Uter, N, Bullock, T, Perona, J.J.
Deposit date:2005-05-01
Release date:2005-06-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:tRNA-dependent Aminoacyl-adenylate Hydrolysis by a Nonediting Class I Aminoacyl-tRNA Synthetase.
J.Biol.Chem., 280, 2005
2GE5
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BU of 2ge5 by Molmil
EcoRV Restriction Endonuclease C-terminal deletion mutant/GATATC/Ca2+
Descriptor: 5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3', CALCIUM ION, Type II restriction enzyme EcoRV
Authors:Hiller, D.A, Perona, J.J.
Deposit date:2006-03-17
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Positively Charged C-Terminal Subdomains of EcoRV Endonuclease: Contributions to DNA Binding, Bending, and Cleavage.
Biochemistry, 45, 2006
1KC6
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BU of 1kc6 by Molmil
HincII Bound to Cognate DNA
Descriptor: 5'-D(P*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*G)-3', SODIUM ION, TYPE II RESTRICTION ENZYME HINCII
Authors:Horton, N.C, Dorner, L.F, Perona, J.J.
Deposit date:2001-11-07
Release date:2001-12-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Sequence selectivity and degeneracy of a restriction endonuclease mediated by DNA intercalation.
Nat.Struct.Biol., 9, 2002
1O0B
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BU of 1o0b by Molmil
CRYSTAL STRUCTURE OF L-GLUTAMINE AND AMPCPP BOUND TO GLUTAMINE AMINOACYL TRNA SYNTHETASE
Descriptor: ADENOSINE MONOPHOSPHATE, GLUTAMINE, Glutaminyl tRNA, ...
Authors:Bullock, T.L, Perona, J.J.
Deposit date:2003-02-20
Release date:2003-04-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Amino Acid Discrimination by a class I aminoacyl-tRNA synthetase specified by negative determinants
J.Mol.Biol., 328, 2003
1O0C
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BU of 1o0c by Molmil
CRYSTAL STRUCTURE OF L-GLUTAMATE AND AMPCPP BOUND TO GLUTAMINE AMINOACYL TRNA SYNTHETASE
Descriptor: ADENOSINE MONOPHOSPHATE, GLUTAMIC ACID, Glutaminyl tRNA, ...
Authors:Bullock, T.L, Perona, J.J.
Deposit date:2003-02-20
Release date:2003-04-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Amino Acid Discrimination by a class I aminoacyl-tRNA synthetase specified by negative determinants
J.Mol.Biol., 328, 2003
1SX5
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BU of 1sx5 by Molmil
K38A EcoRV bound to cleaved DNA and Mn2+: P1 crystal form
Descriptor: 5'-D(*AP*AP*AP*GP*AP*T)-3', 5'-D(P*AP*TP*CP*TP*T)-3', MANGANESE (II) ION, ...
Authors:Horton, N.C, Perona, J.J.
Deposit date:2004-03-30
Release date:2004-04-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:DNA cleavage by EcoRV endonuclease: Two metal ions in three metal ion binding sites
Biochemistry, 43, 2004

 

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