6C5R
| Crystal structure of the soluble domain of the mitochondrial calcium uniporter | Descriptor: | calcium uniporter | Authors: | Fan, C, Fan, M, Fastman, N, Zhang, J, Feng, L. | Deposit date: | 2018-01-16 | Release date: | 2018-07-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.09608316 Å) | Cite: | X-ray and cryo-EM structures of the mitochondrial calcium uniporter. Nature, 559, 2018
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6C5W
| Crystal structure of the mitochondrial calcium uniporter | Descriptor: | CALCIUM ION, calcium uniporter, nanobody | Authors: | Fan, C, Fan, M, Fastman, N, Zhang, J, Feng, L. | Deposit date: | 2018-01-17 | Release date: | 2018-07-11 | Last modified: | 2019-04-24 | Method: | X-RAY DIFFRACTION (3.10010242 Å) | Cite: | X-ray and cryo-EM structures of the mitochondrial calcium uniporter. Nature, 559, 2018
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6PAM
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6PAN
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6PAQ
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6PAO
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6PAR
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7S7Y
| Crystal structure of iCytSnFR Cytisine Sensor precursor binding protein | Descriptor: | IMIDAZOLE, iNicSnFR 4.0 Fluorescent Nicotine Sensor precursor binding protein | Authors: | Fan, C, Nichols, N.L, Luebbert, L, Looger, L.L, Lester, H.A, Rees, D.C. | Deposit date: | 2021-09-17 | Release date: | 2021-10-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure, Function, and Application of Bacterial ABC Transporters Ph.D.Thesis,California Institute of Technology, 2020
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7S7W
| Crystal structure of iNicSnFR3a Nicotine Sensor precursor binding protein | Descriptor: | 1,2-ETHANEDIOL, SODIUM ION, iNicSnFR 3.0 Fluorescent Nicotine Sensor precursor binding protein | Authors: | Fan, C, Shivange, A.V, Looger, L.L, Lester, H.A, Rees, D.C. | Deposit date: | 2021-09-17 | Release date: | 2021-10-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Structure, Function, and Application of Bacterial ABC Transporters Ph.D.Thesis,California Institute of Technology, 2020
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7S80
| Crystal structure of iAChSnFR Acetylcholine Sensor precursor binding protein | Descriptor: | 1,2-ETHANEDIOL, MALONATE ION, iAchSnFR Fluorescent Acetylcholine Sensor precursor binding protein | Authors: | Fan, C, Borden, P.M, Looger, L.L, Lester, H.A, Rees, D.C. | Deposit date: | 2021-09-17 | Release date: | 2021-10-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure, Function, and Application of Bacterial ABC Transporters Ph.D.Thesis,California Institute of Technology, 2020
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7S7Z
| Crystal structure of iAChSnFR Acetylcholine Sensor precursor binding protein with choline bound | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CHOLINE ION, iAchSnFR Fluorescent Acetylcholine Sensor precursor binding protein | Authors: | Fan, C, Borden, P.M, Looger, L.L, Lester, H.A, Rees, D.C. | Deposit date: | 2021-09-17 | Release date: | 2021-10-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure, Function, and Application of Bacterial ABC Transporters Ph.D.Thesis,California Institute of Technology, 2020
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7S7X
| Crystal structure of iCytSnFR Cytisine Sensor precursor binding protein with varenicline bound | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, DI(HYDROXYETHYL)ETHER, VARENICLINE, ... | Authors: | Fan, C, Nichols, N.L, Luebbert, L, Looger, L.L, Lester, H.A, Rees, D.C. | Deposit date: | 2021-09-17 | Release date: | 2021-10-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure, Function, and Application of Bacterial ABC Transporters Ph.D.Thesis,California Institute of Technology, 2020
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7N59
| Structure of AtAtm3 in the inward-facing conformation with GSSG bound | Descriptor: | ABC transporter B family member 25, mitochondrial, OXIDIZED GLUTATHIONE DISULFIDE | Authors: | Fan, C, Rees, D.C. | Deposit date: | 2021-06-05 | Release date: | 2022-04-13 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Glutathione binding to the plant At Atm3 transporter and implications for the conformational coupling of ABC transporters. Elife, 11, 2022
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7N5B
| Structure of AtAtm3 in the outward-facing conformation | Descriptor: | ABC transporter B family member 25, mitochondrial, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Fan, C, Rees, D.C. | Deposit date: | 2021-06-05 | Release date: | 2022-04-13 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Glutathione binding to the plant At Atm3 transporter and implications for the conformational coupling of ABC transporters. Elife, 11, 2022
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7N58
| Structure of AtAtm3 in the inward-facing conformation | Descriptor: | ABC transporter B family member 25, mitochondrial | Authors: | Fan, C, Rees, D.C. | Deposit date: | 2021-06-05 | Release date: | 2022-04-13 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Glutathione binding to the plant At Atm3 transporter and implications for the conformational coupling of ABC transporters. Elife, 11, 2022
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7N5A
| Structure of AtAtm3 in the closed conformation | Descriptor: | ABC transporter B family member 25, mitochondrial, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Fan, C, Rees, D.C. | Deposit date: | 2021-06-05 | Release date: | 2022-04-13 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.95 Å) | Cite: | Glutathione binding to the plant At Atm3 transporter and implications for the conformational coupling of ABC transporters. Elife, 11, 2022
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5BKI
| Blocker-free closed MthK channel in nanodisc | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CADMIUM ION, Calcium-gated potassium channel MthK, ... | Authors: | Fan, C, Nimigean, C.M. | Deposit date: | 2021-03-19 | Release date: | 2022-09-21 | Last modified: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Calcium-gated potassium channel blockade via membrane-facing fenestrations. Nat.Chem.Biol., 2023
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5BKJ
| TPeA-bound closed MthK channel in nanodisc | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 1-(tripentyl-$l^{4}-azanyl)pentane, Calcium-gated potassium channel MthK, ... | Authors: | Fan, C, Nimigean, C.M. | Deposit date: | 2021-03-19 | Release date: | 2022-09-21 | Last modified: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Calcium-gated potassium channel blockade via membrane-facing fenestrations. Nat.Chem.Biol., 2023
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5BKK
| bbTBA-bound closed MthK channel in nanodisc | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, (~{R})-phenyl-[4-[(tributyl-$l^{4}-azanyl)methyl]phenyl]methanol, Calcium-gated potassium channel MthK, ... | Authors: | Fan, C, Nimigean, C.M. | Deposit date: | 2021-03-19 | Release date: | 2022-09-21 | Last modified: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Calcium-gated potassium channel blockade via membrane-facing fenestrations. Nat.Chem.Biol., 2023
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6U5R
| Calcium-bound MthK closed state | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | Authors: | Fan, C, Nimigean, C.M. | Deposit date: | 2019-08-28 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel. Nature, 580, 2020
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6U5P
| Calcium-bound MthK gating ring state 1 | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | Authors: | Fan, C, Nimigean, C.M. | Deposit date: | 2019-08-28 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel. Nature, 580, 2020
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6U68
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6U6D
| MthK closed state with EDTA | Descriptor: | Calcium-gated potassium channel MthK, POTASSIUM ION | Authors: | Fan, C, Rheinberger, J, Nimigean, C.M. | Deposit date: | 2019-08-29 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel. Nature, 580, 2020
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6U6E
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6U5N
| Calcium-bound MthK gating ring state 2 | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | Authors: | Fan, C, Nimigean, C.M. | Deposit date: | 2019-08-28 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel. Nature, 580, 2020
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