6M14
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6m14 by Molmil](/molmil-images/mine/6m14) | Crystal Structure of the BARD1 BRCT Mutant | Descriptor: | BRCA1-associated RING domain protein 1, SULFATE ION | Authors: | Chen, T, Huang, W.T. | Deposit date: | 2020-02-24 | Release date: | 2021-02-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.88001835 Å) | Cite: | BARD1 is an ATPase activating protein for OLA1. Biochim Biophys Acta Gen Subj, 1866, 2022
|
|
6CZ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6cz1 by Molmil](/molmil-images/mine/6cz1) | Crystal structure of ATPase domain of Human GRP78 bound to Ver155008 | Descriptor: | 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitrile, Endoplasmic reticulum chaperone BiP, MAGNESIUM ION | Authors: | Antoshchenko, T, Chen, Y, Hughes, S, Park, H. | Deposit date: | 2018-04-07 | Release date: | 2019-04-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Crystallographic selection of adenosine analogs that fit the mold of the active site of human GRP78 and beyond To be Published
|
|
2JXD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jxd by Molmil](/molmil-images/mine/2jxd) | |
6LW5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lw5 by Molmil](/molmil-images/mine/6lw5) | Crystal structure of the human formyl peptide receptor 2 in complex with WKYMVm | Descriptor: | CHOLESTEROL, Soluble cytochrome b562,N-formyl peptide receptor 2, TRP-LYS-TYR-MET-VAL-QXV | Authors: | Chen, T, Zong, X, Zhang, H, Wang, M, Zhao, Q, Wu, B. | Deposit date: | 2020-02-07 | Release date: | 2020-03-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of ligand binding modes at the human formyl peptide receptor 2. Nat Commun, 11, 2020
|
|
2R75
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2r75 by Molmil](/molmil-images/mine/2r75) | Aquifex aeolicus FtsZ with 8-morpholino-GTP | Descriptor: | 8-morpholin-4-ylguanosine 5'-(tetrahydrogen triphosphate), Cell division protein ftsZ, MAGNESIUM ION | Authors: | Lappchen, T, Pinas, V.A, Hartog, A.F, Koomen, G.J, Schaffner-Barbero, C, Andreu, J.M, Trambaiolo, D, Lowe, J, Juhem, A, Popov, A.V, den Blaauwen, T. | Deposit date: | 2007-09-07 | Release date: | 2008-07-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.402 Å) | Cite: | Probing FtsZ and tubulin with C8-substituted GTP analogs reveals differences in their nucleotide binding sites Chem.Biol., 15, 2008
|
|
5FZT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5fzt by Molmil](/molmil-images/mine/5fzt) | The crystal structure of R7R8 in complex with a DLC1 fragment. | Descriptor: | MALONATE ION, RHO GTPASE-ACTIVATING PROTEIN 7, TALIN-1 | Authors: | Zacharchenko, T, Qian, X, Goult, B.T, Jethwa, D, Almeida, T, Ballestrem, C, Critchley, D.R, Lowy, D.R, Barsukov, I.L. | Deposit date: | 2016-03-15 | Release date: | 2016-04-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Ld Motif Recognition by Talin: Structure of the Talin-Dlc1 Complex. Structure, 24, 2016
|
|
6XXS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xxs by Molmil](/molmil-images/mine/6xxs) | |
6Y3E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y3e by Molmil](/molmil-images/mine/6y3e) | |
6XZZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xzz by Molmil](/molmil-images/mine/6xzz) | |
6Y17
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y17 by Molmil](/molmil-images/mine/6y17) | |
6YBM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ybm by Molmil](/molmil-images/mine/6ybm) | |
6ZBU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zbu by Molmil](/molmil-images/mine/6zbu) | |
6XYX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xyx by Molmil](/molmil-images/mine/6xyx) | |
6XWF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xwf by Molmil](/molmil-images/mine/6xwf) | |
6TBT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tbt by Molmil](/molmil-images/mine/6tbt) | |
6TCJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tcj by Molmil](/molmil-images/mine/6tcj) | |
6GVB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gvb by Molmil](/molmil-images/mine/6gvb) | Crystal structure of Cutibacterium acnes exo-beta-1,4-mannosidase | Descriptor: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, exo-beta-1,4-mannosidase | Authors: | Reichenbach, T, Divne, C. | Deposit date: | 2018-06-20 | Release date: | 2019-07-03 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and biochemical characterization of the Cutibacterium acnes exo-beta-1,4-mannosidase that targets the N-glycan core of host glycoproteins. Plos One, 13, 2018
|
|
2KR7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kr7 by Molmil](/molmil-images/mine/2kr7) | |
8IBH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ibh by Molmil](/molmil-images/mine/8ibh) | Cep57 C-terminal domain | Descriptor: | Centrosomal protein of 57 kDa | Authors: | Chen, T, Yeh, H.-W, Cheng, H.-C. | Deposit date: | 2023-02-10 | Release date: | 2024-02-14 | Last modified: | 2024-06-26 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Cep57 regulates human centrosomes through multivalent interactions. Proc.Natl.Acad.Sci.USA, 121, 2024
|
|
5G4X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5g4x by Molmil](/molmil-images/mine/5g4x) | The crystal structure of the SHANK3 N-terminus | Descriptor: | 1,2-ETHANEDIOL, SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 3 | Authors: | Zacharchenko, T, Barsukov, I. | Deposit date: | 2016-05-17 | Release date: | 2017-01-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.166 Å) | Cite: | SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras. Nat. Cell Biol., 19, 2017
|
|
8AK3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ak3 by Molmil](/molmil-images/mine/8ak3) | |
8AK2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ak2 by Molmil](/molmil-images/mine/8ak2) | Drosophila melanogaster UNC89 Protein Kinase Domain 1 (apo) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Obscurin | Authors: | Dorendorf, T, Zacharchenko, T, Mayans, O. | Deposit date: | 2022-07-29 | Release date: | 2023-03-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | PK1 from Drosophila obscurin is an inactive pseudokinase with scaffolding properties. Open Biology, 13, 2023
|
|
6TWN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6twn by Molmil](/molmil-images/mine/6twn) | Crystal structure of Talin1 R7R8 in complex with CDK1 (206-223) | Descriptor: | CHLORIDE ION, Cyclin-dependent kinase 1, GLYCEROL, ... | Authors: | Zacharchenko, T, Muench, S.P, Goult, B.T. | Deposit date: | 2020-01-13 | Release date: | 2021-05-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Talin mechanosensitivity is modulated by a direct interaction with cyclin-dependent kinase-1. J.Biol.Chem., 297, 2021
|
|
8AS9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8as9 by Molmil](/molmil-images/mine/8as9) | Crystal structure of the talin-KANK1 complex | Descriptor: | B-cell lymphoma 6 protein, GLYCEROL, KN-motif NCoR1 BBD fusion,Nuclear receptor corepressor 1, ... | Authors: | Zacharchenko, T. | Deposit date: | 2022-08-18 | Release date: | 2023-06-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | The structural basis of the talin-KANK1 interaction that coordinates the actin and microtubule cytoskeletons at focal adhesions. Open Biology, 13, 2023
|
|
8BNQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8bnq by Molmil](/molmil-images/mine/8bnq) | |