3SXG
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![BU of 3sxg by Molmil](/molmil-images/mine/3sxg) | Crystal structure of AAAA+UDP+Gal with MPD as the cryoprotectant | Descriptor: | DI(HYDROXYETHYL)ETHER, Histo-blood group ABO system transferase, MANGANESE (II) ION, ... | Authors: | Johal, A.R, Evans, S.V. | Deposit date: | 2011-07-14 | Release date: | 2012-02-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Sequence-dependent effects of cryoprotectants on the active sites of the human ABO(H) blood group A and B glycosyltransferases. Acta Crystallogr.,Sect.D, 68, 2012
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3SX3
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![BU of 3sx3 by Molmil](/molmil-images/mine/3sx3) | Crystal structure of AABB+UDP+Gal with glycerol as the cryoprotectant | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Histo-blood group ABO system transferase, ... | Authors: | Johal, A.R, Evans, S.V. | Deposit date: | 2011-07-14 | Release date: | 2012-02-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Sequence-dependent effects of cryoprotectants on the active sites of the human ABO(H) blood group A and B glycosyltransferases. Acta Crystallogr.,Sect.D, 68, 2012
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3SX8
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![BU of 3sx8 by Molmil](/molmil-images/mine/3sx8) | Crystal structure of ABBA+UDP+Gal with MPD as the cryoprotectant | Descriptor: | DI(HYDROXYETHYL)ETHER, Histo-blood group ABO system transferase, MANGANESE (II) ION, ... | Authors: | Johal, A.R, Evans, S.V. | Deposit date: | 2011-07-14 | Release date: | 2012-02-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Sequence-dependent effects of cryoprotectants on the active sites of the human ABO(H) blood group A and B glycosyltransferases. Acta Crystallogr.,Sect.D, 68, 2012
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3SXE
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![BU of 3sxe by Molmil](/molmil-images/mine/3sxe) | Crystal structure of AAAA+UDP+Gal with Glycerol as the cryoprotectant | Descriptor: | Histo-blood group ABO system transferase, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ... | Authors: | Johal, A.R, Evans, S.V. | Deposit date: | 2011-07-14 | Release date: | 2012-02-29 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Sequence-dependent effects of cryoprotectants on the active sites of the human ABO(H) blood group A and B glycosyltransferases. Acta Crystallogr.,Sect.D, 68, 2012
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2CSN
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![BU of 2csn by Molmil](/molmil-images/mine/2csn) | BINARY COMPLEX OF CASEIN KINASE-1 WITH CKI7 | Descriptor: | CASEIN KINASE-1, N-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE, SULFATE ION | Authors: | Xu, R.-M, Cheng, X. | Deposit date: | 1995-10-11 | Release date: | 1996-03-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for selectivity of the isoquinoline sulfonamide family of protein kinase inhibitors. Proc.Natl.Acad.Sci.USA, 93, 1996
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2VFO
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![BU of 2vfo by Molmil](/molmil-images/mine/2vfo) | Low Temperature Structure of P22 Tailspike Protein Fragment (109-666), Mutant V125L | Descriptor: | CALCIUM ION, GLYCEROL, P22 TAILSPIKE PROTEIN, ... | Authors: | Becker, M, Mueller, J.J, Heinemann, U, Seckler, R. | Deposit date: | 2007-11-05 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Side-Chain Stacking and Beta-Helix Stability in P22 Tailspike Protein To be Published
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2VFQ
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![BU of 2vfq by Molmil](/molmil-images/mine/2vfq) | Low Temperature Structure of P22 Tailspike Protein Fragment (109-666), Mutant V450A | Descriptor: | CALCIUM ION, GLYCEROL, P22 TAILSPIKE PROTEIN,, ... | Authors: | Becker, M, Mueller, J.J, Heinemann, U, Seckler, R. | Deposit date: | 2007-11-05 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Side-Chain Stacking and Beta-Helix Stability in P22 Tailspike Protein To be Published
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2VFN
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![BU of 2vfn by Molmil](/molmil-images/mine/2vfn) | Low Temperature Structure of P22 Tailspike Protein Fragment (109-666), Mutant V125A | Descriptor: | BIFUNCTIONAL TAIL PROTEIN, CALCIUM ION, GLYCEROL, ... | Authors: | Becker, M, Mueller, J.J, Heinemann, U, Seckler, R. | Deposit date: | 2007-11-05 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Side-Chain Stacking and Beta-Helix Stability in P22 Tailspike Protein To be Published
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2VFM
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![BU of 2vfm by Molmil](/molmil-images/mine/2vfm) | Low Temperature Structure of P22 Tailspike Protein Fragment (109-666) | Descriptor: | BIFUNCTIONAL TAIL PROTEIN, CALCIUM ION, GLYCEROL, ... | Authors: | Becker, M, Mueller, J.J, Heinemann, U, Seckler, R. | Deposit date: | 2007-11-05 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Side-Chain Stacking and Beta-Helix Stability in P22 Tailspike Protein To be Published
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2VFP
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![BU of 2vfp by Molmil](/molmil-images/mine/2vfp) | Low Temperature Structure of P22 Tailspike Protein Fragment (109-666), Mutant V349L | Descriptor: | CALCIUM ION, GLYCEROL, P22 TAILSPIKE PROTEIN, ... | Authors: | Becker, M, Mueller, J.J, Heinemann, U, Seckler, R. | Deposit date: | 2007-11-05 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Side-Chain Stacking and Beta-Helix Stability in P22 Tailspike Protein To be Published
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1CSN
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![BU of 1csn by Molmil](/molmil-images/mine/1csn) | BINARY COMPLEX OF CASEIN KINASE-1 WITH MGATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CASEIN KINASE-1, MAGNESIUM ION, ... | Authors: | Xu, R.-M, Cheng, X. | Deposit date: | 1995-04-25 | Release date: | 1995-07-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of casein kinase-1, a phosphate-directed protein kinase. EMBO J., 14, 1995
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5T9U
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![BU of 5t9u by Molmil](/molmil-images/mine/5t9u) | Discovery of a Potent Cyclophilin Inhibitor (Compound 3) based on Structural Simplification of Sanglifehrin A | Descriptor: | 3-[(3-hydroxyphenyl)methyl]-10,12-dimethoxy-9,11-dimethyl-6-(propan-2-yl)-19-oxa-1,4,7,25-tetraazabicyclo[19.3.1]pentacosa-13,15-diene-2,5,8,20-tetrone, Peptidyl-prolyl cis-trans isomerase A | Authors: | Appleby, T.C, Steadman, V, Pettit, S, Schmitz, U, Mackman, R.L, Schultz, B. | Deposit date: | 2016-09-09 | Release date: | 2017-01-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A. J. Med. Chem., 60, 2017
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5T9Z
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![BU of 5t9z by Molmil](/molmil-images/mine/5t9z) | Discovery of a Potent Cyclophilin Inhibitor (Compound 6) based on Structural Simplification of Sanglifehrin A | Descriptor: | 11-[(3-hydroxyphenyl)methyl]-18-methoxy-17-methyl-14-(propan-2-yl)-3-oxa-9,12,15,28-tetraazatricyclo[21.3.1.1~5,9~]octacosa-1(27),21,23,25-tetraene-4,10,13,16-tetrone, Peptidyl-prolyl cis-trans isomerase A | Authors: | Appleby, T.C, Steadman, V, Pettit, S, Schmitz, U, Mackman, R.L, Schultz, B. | Deposit date: | 2016-09-09 | Release date: | 2017-01-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A. J. Med. Chem., 60, 2017
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5TA2
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![BU of 5ta2 by Molmil](/molmil-images/mine/5ta2) | Discovery of a Potent Cyclophilin Inhibitor (Compound 7) based on Structural Simplification of Sanglifehrin A | Descriptor: | 11-[(3-hydroxyphenyl)methyl]-18-methoxy-2,17-dimethyl-14-(propan-2-yl)-3-oxa-9,12,15,28-tetraazatricyclo[21.3.1.1~5,9~]octacosa-1(27),21,23,25-tetraene-4,10,13,16-tetrone, Peptidyl-prolyl cis-trans isomerase A | Authors: | Appleby, T.C, Steadman, V, Pettit, S, Schmitz, U, Mackman, R.L, Schultz, B. | Deposit date: | 2016-09-09 | Release date: | 2017-01-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A. J. Med. Chem., 60, 2017
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5V4K
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![BU of 5v4k by Molmil](/molmil-images/mine/5v4k) | Crystal structure of NEDD4 LIR-fused human LC3B_2-119 | Descriptor: | GLYCEROL, Microtubule-associated proteins 1A/1B light chain 3B,Microtubule-associated proteins 1A/1B light chain 3B,Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION | Authors: | Qiu, Y, Zheng, Y, Schulman, B. | Deposit date: | 2017-03-09 | Release date: | 2017-05-17 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.099 Å) | Cite: | Insights into links between autophagy and the ubiquitin system from the structure of LC3B bound to the LIR motif from the E3 ligase NEDD4. Protein Sci., 26, 2017
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5TA4
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![BU of 5ta4 by Molmil](/molmil-images/mine/5ta4) | Discovery of a Potent Cyclophilin Inhibitor (Compound 8) based on Structural Simplification of Sanglifehrin A | Descriptor: | 18-methoxy-2,11,17-trimethyl-14-(propan-2-yl)-3-oxa-9,12,15,28-tetraazatricyclo[21.3.1.1~5,9~]octacosa-1(27),21,23,25-tetraene-4,10,13,16-tetrone, Peptidyl-prolyl cis-trans isomerase A, SULFATE ION | Authors: | Appleby, T.C, Steadman, V, Pettit, S, Schmitz, U, Mackman, R.L, Schultz, B. | Deposit date: | 2016-09-09 | Release date: | 2017-01-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A. J. Med. Chem., 60, 2017
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5T9W
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![BU of 5t9w by Molmil](/molmil-images/mine/5t9w) | Discovery of a Potent Cyclophilin Inhibitor (Compound 5) based on Structural Simplification of Sanglifehrin A | Descriptor: | 3-[(3-hydroxyphenyl)methyl]-6-(propan-2-yl)-19-oxa-1,4,7,25-tetraazabicyclo[19.3.1]pentacosa-13,15-diene-2,5,8,20-tetrone, Peptidyl-prolyl cis-trans isomerase A | Authors: | Appleby, T.C, Steadman, V, Pettit, P, Schmitz, U, Mackman, R.L, Schultz, B. | Deposit date: | 2016-09-09 | Release date: | 2017-01-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of Potent Cyclophilin Inhibitors Based on the Structural Simplification of Sanglifehrin A. J. Med. Chem., 60, 2017
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5TJN
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![BU of 5tjn by Molmil](/molmil-images/mine/5tjn) | Crystal structure of GTB + B trisaccharide (native) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Histo-blood group ABO system transferase, alpha-L-fucopyranose-(1-2)-[alpha-D-galactopyranose-(1-3)]octyl beta-D-galactopyranoside | Authors: | Legg, M.S.G, Gagnon, S.M.L, Evans, S.V. | Deposit date: | 2016-10-04 | Release date: | 2017-06-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | High-resolution crystal structures and STD NMR mapping of human ABO(H) blood group glycosyltransferases in complex with trisaccharide reaction products suggest a molecular basis for product release. Glycobiology, 27, 2017
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5TJK
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![BU of 5tjk by Molmil](/molmil-images/mine/5tjk) | Crystal structure of GTA + A trisaccharide (native) | Descriptor: | GLYCEROL, Histo-blood group ABO system transferase, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]octyl beta-D-galactopyranoside | Authors: | Legg, M.S.G, Gagnon, S.M.L, Evans, S.V. | Deposit date: | 2016-10-04 | Release date: | 2017-06-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | High-resolution crystal structures and STD NMR mapping of human ABO(H) blood group glycosyltransferases in complex with trisaccharide reaction products suggest a molecular basis for product release. Glycobiology, 27, 2017
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5TJL
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![BU of 5tjl by Molmil](/molmil-images/mine/5tjl) | Crystal structure of GTA + A trisaccharide (mercury derivative) | Descriptor: | Histo-blood group ABO system transferase, MERCURY (II) ION, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]octyl beta-D-galactopyranoside | Authors: | Legg, M.S.G, Gagnon, S.M.L, Evans, S.V. | Deposit date: | 2016-10-04 | Release date: | 2017-06-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | High-resolution crystal structures and STD NMR mapping of human ABO(H) blood group glycosyltransferases in complex with trisaccharide reaction products suggest a molecular basis for product release. Glycobiology, 27, 2017
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5TJO
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![BU of 5tjo by Molmil](/molmil-images/mine/5tjo) | Crystal structure of GTB + B trisaccharide (mercury derivative) | Descriptor: | Histo-blood group ABO system transferase, MERCURY (II) ION, alpha-L-fucopyranose-(1-2)-[alpha-D-galactopyranose-(1-3)]octyl beta-D-galactopyranoside | Authors: | Legg, M.S.G, Gagnon, S.M.L, Evans, S.V. | Deposit date: | 2016-10-04 | Release date: | 2017-06-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | High-resolution crystal structures and STD NMR mapping of human ABO(H) blood group glycosyltransferases in complex with trisaccharide reaction products suggest a molecular basis for product release. Glycobiology, 27, 2017
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