5TJL

Crystal structure of GTA + A trisaccharide (mercury derivative)

Summary for 5TJL

Entry DOI	10.2210/pdb5tjl/pdb
Related	5TJK 5TJM 5TJN 5TJO 5TJP
Descriptor	Histo-blood group ABO system transferase, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]octyl beta-D-galactopyranoside, MERCURY (II) ION, ... (4 entities in total)
Functional Keywords	glycosyltransferases, histo blood group enzymes, product trisaccharide, gt-a fold, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	36008.96
Authors	Legg, M.S.G.,Gagnon, S.M.L.,Evans, S.V. (deposition date: 2016-10-04, release date: 2017-06-14, Last modification date: 2023-10-04)
Primary citation	Gagnon, S.M.L.,Legg, M.S.G.,Sindhuwinata, N.,Letts, J.A.,Johal, A.R.,Schuman, B.,Borisova, S.N.,Palcic, M.M.,Peters, T.,Evans, S.V. High-resolution crystal structures and STD NMR mapping of human ABO(H) blood group glycosyltransferases in complex with trisaccharide reaction products suggest a molecular basis for product release. Glycobiology, 27:966-977, 2017 Cited by PubMed: 28575295 DOI: 10.1093/glycob/cwx053 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.89 Å)

Structure validation