7FCF
 
 | | Crystal structure of T6SS Hcp protein | | Descriptor: | Fimbrial protein | | Authors: | Jobichen, C, Sivaraman, J. | | Deposit date: | 2021-07-14 | | Release date: | 2022-07-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Bacterial antagonism of Chromobacterium haemolyticum and characterization of its putative type VI secretion system.
Res.Microbiol., 173, 2022
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7CBK
 | | Structure of Human Neutrophil Elastase Ecotin complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ecotin, ... | | Authors: | Jobichen, C, Sivaraman, J. | | Deposit date: | 2020-06-12 | | Release date: | 2020-08-12 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural Basis for the Inhibition Mechanism of Ecotin against Neutrophil Elastase by Targeting the Active Site and Secondary Binding Site.
Biochemistry, 59, 2020
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1KAH
 | | L-HISTIDINOL DEHYDROGENASE (HISD) STRUCTURE COMPLEXED WITH L-HISTIDINE (PRODUCT), ZN AND NAD (COFACTOR) | | Descriptor: | HISTIDINE, Histidinol dehydrogenase, ZINC ION | | Authors: | Barbosa, J.A.R.G, Sivaraman, J, Li, Y, Larocque, R, Matte, A, Schrag, J.D, Cygler, M. | | Deposit date: | 2001-11-02 | | Release date: | 2002-06-12 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase.
Proc.Natl.Acad.Sci.USA, 99, 2002
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7EQZ
 | | Crystal structure of Carboxypeptidase B complexed with Potato Carboxypeptidase Inhibitor | | Descriptor: | Carboxypeptidase B, GLYCINE, Metallocarboxypeptidase inhibitor, ... | | Authors: | Choong, Y.K, Gavor, E, Jobichen, C, Sivaraman, J. | | Deposit date: | 2021-05-05 | | Release date: | 2021-11-10 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of Aedes aegypti carboxypeptidase B1-inhibitor complex uncover the disparity between mosquito and non-mosquito insect carboxypeptidase inhibition mechanism.
Protein Sci., 30, 2021
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4O7D
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4N7D
 | | Selenomethionine incorporated Bla g 4 | | Descriptor: | Bla g 4 allergen variant 1, CITRIC ACID, GLYCEROL | | Authors: | Offermann, L.R, Chan, S.L, Osinski, T, Tan, Y.W, Chew, F.T, Sivaraman, J, Mok, Y.K, Minor, W, Chruszcz, M. | | Deposit date: | 2013-10-15 | | Release date: | 2014-05-21 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The major cockroach allergen Bla g 4 binds tyramine and octopamine.
Mol.Immunol., 60, 2014
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1NPZ
 | | Crystal structures of Cathepsin S inhibitor complexes | | Descriptor: | Cathepsin S, N~2~-(morpholin-4-ylcarbonyl)-N-[(3S)-1-phenyl-5-(phenylsulfonyl)pentan-3-yl]-L-leucinamide | | Authors: | Pauly, T.A, Sulea, T, Ammirati, M, Sivaraman, J, Danley, D.E, Griffor, M.C, Kamath, A.V, Wang, I.K, Laird, E.R, Seddon, A.P, Menard, R, Cygler, M, Rath, V.L. | | Deposit date: | 2003-01-20 | | Release date: | 2003-04-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Specificity determinants of human cathepsin s revealed
by crystal structures of complexes.
Biochemistry, 42, 2003
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1NQC
 | | Crystal structures of Cathepsin S inhibitor complexes | | Descriptor: | Cathepsin S, N-[(1R)-2-(BENZYLSULFANYL)-1-FORMYLETHYL]-N-(MORPHOLIN-4-YLCARBONYL)-L-PHENYLALANINAMIDE | | Authors: | Pauly, T.A, Sulea, T, Ammirati, M, Sivaraman, J, Danley, D.E, Griffor, M.C, Kamath, A.V, Wang, I.K, Laird, E.R, Menard, R, Cygler, M, Rath, V.L. | | Deposit date: | 2003-01-21 | | Release date: | 2003-04-15 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Specificity determinants of human cathepsin s revealed
by crystal structures of complexes.
Biochemistry, 42, 2003
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1EOL
 | | Design of P1' and P3' residues of trivalent thrombin inhibitors and their crystal structures | | Descriptor: | ALPHA THROMBIN, THROMBIN INHIBITOR P628 | | Authors: | Slon-Usakiewicz, J.J, Sivaraman, J, Li, Y, Cygler, M, Konishi, Y. | | Deposit date: | 2000-03-23 | | Release date: | 2000-05-03 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Design of P1' and P3' residues of trivalent thrombin inhibitors and their crystal structures.
Biochemistry, 39, 2000
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1FC4
 | | 2-AMINO-3-KETOBUTYRATE COA LIGASE | | Descriptor: | 2-AMINO-3-KETOBUTYRATE CONENZYME A LIGASE, 2-AMINO-3-KETOBUTYRIC ACID, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Schmidt, A, Matte, A, Li, Y, Sivaraman, J, Larocque, R, Schrag, J.D, Smith, C, Sauve, V, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | Deposit date: | 2000-07-17 | | Release date: | 2001-05-02 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Three-dimensional structure of 2-amino-3-ketobutyrate CoA ligase from Escherichia coli complexed with a PLP-substrate intermediate: inferred reaction mechanism.
Biochemistry, 40, 2001
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1EOJ
 | | Design of P1' and P3' residues of trivalent thrombin inhibitors and their crystal structures | | Descriptor: | ALPHA THROMBIN, THROMBIN INHIBITOR P798 | | Authors: | Slon-Usakiewicz, J.J, Sivaraman, J, Li, Y, Cygler, M, Konishi, Y. | | Deposit date: | 2000-03-23 | | Release date: | 2000-05-03 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Design of P1' and P3' residues of trivalent thrombin inhibitors and their crystal structures.
Biochemistry, 39, 2000
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3RKD
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3RJ2
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3RKC
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3WX6
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3WFN
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3WXX
 | | Crystal Structure of a T3SS complex from Aeromonas hydrophila | | Descriptor: | AcrH, AopB, MAGNESIUM ION | | Authors: | Nguyen, V.S, Jobichen, C, Sivaraman, J, Henry, Y.K.M. | | Deposit date: | 2014-08-12 | | Release date: | 2015-10-14 | | Last modified: | 2015-11-11 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure of AcrH-AopB Chaperone-Translocator Complex Reveals a Role for Membrane Hairpins in Type III Secretion System Translocon Assembly
Structure, 23, 2015
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3OB1
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3PH0
 | | Crystal structure of the heteromolecular chaperone, AscE-AscG, from the type III secretion system in Aeromonas hydrophila | | Descriptor: | AscE, AscG | | Authors: | Chatterjee, C, Kumar, S, Chakraborty, S, Tan, Y.W, Leung, K.Y, Sivaraman, J, Mok, Y.K. | | Deposit date: | 2010-11-03 | | Release date: | 2011-07-20 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the heteromolecular chaperone, AscE-AscG, from the type III secretion system in Aeromonas hydrophila
Plos One, 6, 2011
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3PIS
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3PLC
 | | Crystal structure of Beta-Cardiotoxin, a novel three-finger cardiotoxin from the venom of Ophiophagus hannah | | Descriptor: | Beta-cardiotoxin OH-27 | | Authors: | Roy, A, Qingxiang, S, Kini, R.M, Sivaraman, J. | | Deposit date: | 2010-11-15 | | Release date: | 2011-11-16 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Identification of a alpha-helical molten globule intermediate and structural characterization of beta-cardiotoxin, an all beta-sheet protein isolated from the venom of Ophiophagus hannah (king cobra).
Protein Sci., 28, 2019
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3PLF
 | | Reverse Binding Mode of MetRD peptide complexed with c-Cbl TKB domain | | Descriptor: | CALCIUM ION, CHLORIDE ION, E3 ubiquitin-protein ligase CBL, ... | | Authors: | Sun, Q, Sivaraman, J. | | Deposit date: | 2010-11-15 | | Release date: | 2010-12-01 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | An adjacent arginine, and the phosphorylated tyrosine in the c-Met receptor target sequence, dictates the orientation of c-Cbl binding
Febs Lett., 585, 2011
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3QTL
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3OB2
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3OF8
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