7CBK
Structure of Human Neutrophil Elastase Ecotin complex
Summary for 7CBK
| Entry DOI | 10.2210/pdb7cbk/pdb |
| Descriptor | Ecotin, Neutrophil elastase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
| Functional Keywords | protease-inhibitor complex, lyase |
| Biological source | Escherichia coli K-12 More |
| Total number of polymer chains | 4 |
| Total formula weight | 95767.51 |
| Authors | Jobichen, C.,Sivaraman, J. (deposition date: 2020-06-12, release date: 2020-08-12, Last modification date: 2023-11-29) |
| Primary citation | Jobichen, C.,Prabhakar, M.T.,Loh, S.N.,Sivaraman, J. Structural Basis for the Inhibition Mechanism of Ecotin against Neutrophil Elastase by Targeting the Active Site and Secondary Binding Site. Biochemistry, 59:2788-2795, 2020 Cited by PubMed: 32657577DOI: 10.1021/acs.biochem.0c00493 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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