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Crystal structure of the L317I mutant of the C-src tyrosine kinase domain complexed with pyrazolopyrimidine 5
Descriptor:	1-{4-[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]phenyl}-3-[3-(trifluoromethyl)phenyl]urea, Proto-oncogene tyrosine-protein kinase Src
Authors:	Boubeva, R, Pernot, L, Perozzo, R, Scapozza, L.
Deposit date:	2011-02-02
Release date:	2012-02-08
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (2.75 Å)
Cite:	A single amino-acid dictates the dynamics of the switch between active and inactive C-src conformation To be Published