7NZP
 
 | | D-lyxose isomerase from the hyperthermophilic archaeon Thermofilum sp complexed with D-fructose | | Descriptor: | 1,2-ETHANEDIOL, D-lyxose/D-mannose family sugar isomerase, MANGANESE (II) ION, ... | | Authors: | De Rose, S.A, Isupov, M.N, Littlechild, J.A, Schoenheit, P. | | Deposit date: | 2021-03-24 | | Release date: | 2021-10-13 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.345 Å) | | Cite: | Biochemical and Structural Characterisation of a Novel D-Lyxose Isomerase From the Hyperthermophilic Archaeon Thermofilum sp.
Front Bioeng Biotechnol, 9, 2021
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7P7W
 | | N-acetylglucosamine kinase from Plesiomonas shigelloides compexed with alpha-N-acetylglucosamine and ADP | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Roy, S, Isupov, M.N, Harmer, N.J, Ames, J.R. | | Deposit date: | 2021-07-20 | | Release date: | 2022-08-03 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases
J.Biol.Chem., 2022
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7P7I
 | | Native structure of N-acetylglucosamine kinase from Plesiomonas shigelloides | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | | Authors: | Roy, S, Isupov, M.N, Harmer, N.J, Ames, J.R. | | Deposit date: | 2021-07-19 | | Release date: | 2022-07-27 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases
J.Biol.Chem., 2022
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7P9L
 | | N-acetylglucosamine kinase from Plesiomonas shigelloides compexed with alpha-N-acetylglucosamine-6-phosphate | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-6-O-phosphono-beta-D-glucopyranose, ... | | Authors: | Roy, S, Isupov, M.N, Harmer, N.J, Ames, J.R. | | Deposit date: | 2021-07-27 | | Release date: | 2022-08-10 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases
J.Biol.Chem., 2022
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7P9P
 | | N-acetylglucosamine kinase from Plesiomonas shigelloides compexed with alpha-N-acetylglucosamine and AMP-PNP inhibitor | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Roy, S, Isupov, M.N, Harmer, N.J, Ames, J.R. | | Deposit date: | 2021-07-27 | | Release date: | 2022-08-10 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases
J.Biol.Chem., 2022
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7PA1
 | | Structure of N-acetylglucosamine kinase from Plesiomonas shigelloides in complex with AMP-PNP in the absence of N-acetylglucoseamine substrate | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Roy, S, Isupov, M.N, Harmer, N.J, Ames, J.R. | | Deposit date: | 2021-07-28 | | Release date: | 2022-08-10 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases
J.Biol.Chem., 2022
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7P9Y
 | | N-acetylglucosamine kinase from Plesiomonas shigelloides compexed with alpha-N-acetylglucosamine | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ... | | Authors: | Roy, S, Isupov, M.N, Harmer, N.J, Ames, J.R. | | Deposit date: | 2021-07-28 | | Release date: | 2022-08-10 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases
J.Biol.Chem., 2022
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2WBM
 | | Crystal structure of mthSBDS, the homologue of the Shwachman-Bodian- Diamond syndrome protein in the euriarchaeon Methanothermobacter thermautotrophicus | | Descriptor: | CHLORIDE ION, GLYCEROL, RIBOSOME MATURATION PROTEIN SDO1 HOMOLOG, ... | | Authors: | Ng, C.L, Isupov, M.N, Lebedev, A.A, Ortiz-Lombardia, M, Antson, A.A. | | Deposit date: | 2009-03-02 | | Release date: | 2009-06-02 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Conformational Flexibility and Molecular Interactions of an Archaeal Homologue of the Shwachman-Bodian-Diamond Syndrome Protein.
Bmc Struct.Biol., 9, 2009
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2WDU
 | | Fasciola hepatica sigma class GST | | Descriptor: | BROMIDE ION, DIMETHYL SULFOXIDE, GLUTATHIONE, ... | | Authors: | Line, K, Isupov, M.N, LaCourse, E.J, Brophy, P.M, Littlechild, J.A. | | Deposit date: | 2009-03-26 | | Release date: | 2010-04-21 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | The 1.6 Angstrom Crystal Structure of the Fasciola Hepatica Sigma Class Gst
To be Published
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2WB9
 | | Fasciola hepatica sigma class GST | | Descriptor: | BROMIDE ION, CYSTEINE, GLUTATHIONE, ... | | Authors: | Line, K, Isupov, M.N, LaCourse, J, Brophy, P.M, Littlechild, J.A. | | Deposit date: | 2009-02-23 | | Release date: | 2010-03-31 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | The 1.6 Angstrom Crystal Structure of the Fasciola Hepatica Sigma Class Gst
To be Published
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2VXI
 | | The binding of heme and zinc in Escherichia coli Bacterioferritin | | Descriptor: | BACTERIOFERRITIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... | | Authors: | Willies, S.C, Isupov, M.N, Garman, E.F, Littlechild, J.A. | | Deposit date: | 2008-07-04 | | Release date: | 2008-11-04 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | The Binding of Haem and Zinc in the 1.9 A X-Ray Structure of Escherichia Coli Bacterioferritin.
J.Biol.Inorg.Chem., 14, 2009
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2WRT
 | | The 2.4 Angstrom structure of the Fasciola hepatica mu class GST, GST26 | | Descriptor: | CHLORIDE ION, GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME 51 | | Authors: | Line, K, Isupov, M.N, LaCourse, E.J, Brophy, P.M, Littlechild, J.A. | | Deposit date: | 2009-09-02 | | Release date: | 2010-09-29 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The 2.5 Angstrom Structure of a Mu Class Gst from Fasciola Hepatica
To be Published
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2W43
 | | Structure of L-haloacid dehalogenase from S. tokodaii | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HYPOTHETICAL 2-HALOALKANOIC ACID DEHALOGENASE, PHOSPHATE ION | | Authors: | Rye, C.A, Isupov, M.N, Lebedev, A.A, Littlechild, J.A. | | Deposit date: | 2008-11-21 | | Release date: | 2008-12-09 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Biochemical and Structural Studies of a L-Haloacid Dehalogenase from the Thermophilic Archaeon Sulfolobus Tokodaii.
Extremophiles, 13, 2009
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2V9P
 | | Crystal structure of papillomavirus E1 hexameric helicase DNA-free form | | Descriptor: | MAGNESIUM ION, PHOSPHATE ION, REPLICATION PROTEIN E1 | | Authors: | Sanders, C.M, Kovalevskiy, O.V, Sizov, D, Lebedev, A.A, Isupov, M.N, Antson, A.A. | | Deposit date: | 2007-08-24 | | Release date: | 2007-10-02 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Papillomavirus E1 Helicase Assembly Maintains an Asymmetric State in the Absence of DNA and Nucleotide Cofactors.
Nucleic Acids Res., 35, 2007
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2WS2
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2VIM
 | | X-ray structure of Fasciola hepatica thioredoxin | | Descriptor: | THIOREDOXIN | | Authors: | Line, K, Isupov, M.N, Garcia-Rodriguez, E, Maggioli, G, Parra, F, Littlechild, J.A. | | Deposit date: | 2007-12-05 | | Release date: | 2008-07-29 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.38 Å) | | Cite: | The Fasciola Hepatica Thioredoxin: High Resolution Structure Reveals Two Oxidation States.
Mol.Biochem.Parasitol., 161, 2008
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4COQ
 | | The complex of alpha-Carbonic anhydrase from Thermovibrio ammonificans with inhibitor sulfanilamide. | | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, CARBONATE DEHYDRATASE, CHLORIDE ION, ... | | Authors: | James, P, Isupov, M.N, Sayer, C, Berg, S, Lioliou, M, Kotlar, H, Littlechild, J.A. | | Deposit date: | 2014-01-30 | | Release date: | 2014-10-15 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | The Structure of a Tetrameric [Alpha]-Carbonic Anhydrase from Thermovibrio Ammonificans Reveals a Core Formed Around Intermolecular Disulfides that Contribute to its Thermostability
Acta Crystallogr.,Sect.D, 70, 2014
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7PVI
 | | dTDP-sugar epimerase | | Descriptor: | CITRATE ANION, SODIUM ION, alpha-D-xylopyranose, ... | | Authors: | Cross, A.R, Harmer, N.J, Isupov, M.N. | | Deposit date: | 2021-10-04 | | Release date: | 2022-04-20 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.434 Å) | | Cite: | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
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7PWB
 | | dTDP-sugar epimerase from Coxiella burnetii in complex with dTDP | | Descriptor: | 1,2-ETHANEDIOL, CITRIC ACID, THYMIDINE-5'-DIPHOSPHATE, ... | | Authors: | Cross, A.R, Harmer, N.J, Isupov, M.N. | | Deposit date: | 2021-10-06 | | Release date: | 2022-04-20 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
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7PWH
 | | Structure of the dTDP-sugar epimerase StrM | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, THYMIDINE-5'-DIPHOSPHATE, ... | | Authors: | Cross, A.R, Harmer, N.J, Isupov, M.N. | | Deposit date: | 2021-10-06 | | Release date: | 2022-04-20 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
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7PWI
 | | Structure of the dTDP-sugar epimerase StrM | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, dTDP-4-keto-rhamnose 3,5-epimerase,dTDP-4-dehydrorhamnose 3,5-epimerase | | Authors: | Cross, A.R, Harmer, N.J, Isupov, M.N. | | Deposit date: | 2021-10-06 | | Release date: | 2022-04-20 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.326 Å) | | Cite: | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
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7PQ9
 | | Crystal structure of Bacillus clausii pdxR at 2.8 Angstroms resolution | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Vivoli Vega, M, Isupov, M.N, Harmer, N. | | Deposit date: | 2021-09-16 | | Release date: | 2022-09-28 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR.
Nucleic Acids Res., 51, 2023
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7QCA
 | | Spraguea lophii ribosome | | Descriptor: | 40S Ribosomal protein S19, 40S ribosomal protein S0, 40S ribosomal protein S10, ... | | Authors: | Gil Diez, P, McLaren, M, Isupov, M.N, Daum, B, Conners, R, Williams, B. | | Deposit date: | 2021-11-22 | | Release date: | 2022-11-30 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.79 Å) | | Cite: | CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state
Nat Microbiol, 2023
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4CF4
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4CF5
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