6KHU
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6K3F
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6L4H
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![BU of 6l4h by Molmil](/molmil-images/mine/6l4h) | Crystal structure of human NDRG3 C30S mutant | Descriptor: | Protein NDRG3 | Authors: | Kim, K.R, Han, B.W. | Deposit date: | 2019-10-16 | Release date: | 2020-08-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural and Biophysical Analyses of Human N-Myc Downstream-Regulated Gene 3 (NDRG3) Protein. Biomolecules, 10, 2020
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6L4B
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![BU of 6l4b by Molmil](/molmil-images/mine/6l4b) | Crystal structure of human WT NDRG3 | Descriptor: | Protein NDRG3 | Authors: | Kim, K.R, Han, B.W. | Deposit date: | 2019-10-16 | Release date: | 2020-08-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and Biophysical Analyses of Human N-Myc Downstream-Regulated Gene 3 (NDRG3) Protein. Biomolecules, 10, 2020
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7LM2
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![BU of 7lm2 by Molmil](/molmil-images/mine/7lm2) | HUMAN PI3KDELTA IN COMPLEX WITH COMPOUND 3C | Descriptor: | 1,2-ETHANEDIOL, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, ... | Authors: | Lesburg, C.A, Augustin, M. | Deposit date: | 2021-02-05 | Release date: | 2021-04-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Projected Dose Optimization of Amino- and Hydroxypyrrolidine Purine PI3K delta Immunomodulators. J.Med.Chem., 64, 2021
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1IX1
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![BU of 1ix1 by Molmil](/molmil-images/mine/1ix1) | Crystal Structure of P.aeruginosa Peptide deformylase Complexed with Antibiotic Actinonin | Descriptor: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, ACTINONIN, ZINC ION, ... | Authors: | Kim, H.-W, Yoon, H.-J, Lee, J.Y, Han, B.W, Yang, J.K, Lee, B.I, Ahn, H.J, Lee, H.H, Suh, S.W. | Deposit date: | 2002-06-07 | Release date: | 2003-09-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of peptide deformylase from Staphylococcus aureus in complex with actinonin, a naturally occurring antibacterial agent Proteins, 57, 2004
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2GJL
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![BU of 2gjl by Molmil](/molmil-images/mine/2gjl) | Crystal Structure of 2-nitropropane dioxygenase | Descriptor: | FLAVIN MONONUCLEOTIDE, hypothetical protein PA1024 | Authors: | Suh, S.W. | Deposit date: | 2006-03-31 | Release date: | 2006-05-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of 2-Nitropropane Dioxygenase Complexed with FMN and Substrate: identification of the catalytic base J.Biol.Chem., 281, 2006
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2GJN
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6JKG
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![BU of 6jkg by Molmil](/molmil-images/mine/6jkg) | The NAD+-free form of human NSDHL | Descriptor: | Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating | Authors: | Kim, D, Lee, S.J, Lee, B. | Deposit date: | 2019-02-28 | Release date: | 2020-03-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structures of human NSDHL and development of its novel inhibitor with the potential to suppress EGFR activity. Cell.Mol.Life Sci., 78, 2021
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6JKH
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![BU of 6jkh by Molmil](/molmil-images/mine/6jkh) | The NAD+-bound form of human NSDHL | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating | Authors: | Kim, D, Lee, S.J, Lee, B. | Deposit date: | 2019-02-28 | Release date: | 2020-03-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structures of human NSDHL and development of its novel inhibitor with the potential to suppress EGFR activity. Cell.Mol.Life Sci., 78, 2021
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6IFM
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![BU of 6ifm by Molmil](/molmil-images/mine/6ifm) | Crystal structure of DNA bound VapBC from Salmonella typhimurium | Descriptor: | Antitoxin VapB, DNA backward (27-MER), DNA forward (27-MER), ... | Authors: | Park, D.W, Lee, B.J. | Deposit date: | 2018-09-20 | Release date: | 2020-01-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.804 Å) | Cite: | Crystal structure of proteolyzed VapBC and DNA-bound VapBC from Salmonella enterica Typhimurium LT2 and VapC as a putative Ca2+-dependent ribonuclease. Faseb J., 34, 2020
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6IFC
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![BU of 6ifc by Molmil](/molmil-images/mine/6ifc) | Crystal structure of VapBC from Salmonella typhimurium | Descriptor: | Antitoxin VapB, CALCIUM ION, tRNA(fMet)-specific endonuclease VapC | Authors: | Park, D.W, Lee, B.J. | Deposit date: | 2018-09-19 | Release date: | 2020-01-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Crystal structure of proteolyzed VapBC and DNA-bound VapBC from Salmonella enterica Typhimurium LT2 and VapC as a putative Ca2+-dependent ribonuclease. Faseb J., 34, 2020
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3BIZ
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![BU of 3biz by Molmil](/molmil-images/mine/3biz) | Wee1 kinase complex with inhibitor PD331618 | Descriptor: | 4-(2-chlorophenyl)-8-[3-(dimethylamino)propoxy]-9-hydroxy-6-methylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione, CHLORIDE ION, Wee1-like protein kinase | Authors: | Squire, C.J, Dickson, J.M, Ivanovic, I, Baker, E.N. | Deposit date: | 2007-12-02 | Release date: | 2007-12-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Synthesis and structure-activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of the Wee1 and Chk1 checkpoint kinases. Bioorg.Med.Chem.Lett., 18, 2008
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3BI6
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![BU of 3bi6 by Molmil](/molmil-images/mine/3bi6) | Wee1 kinase complex with inhibitor PD352396 | Descriptor: | 4-(2-chlorophenyl)-9-hydroxy-6-methyl-1,3-dioxo-N-(2-pyrrolidin-1-ylethyl)pyrrolo[3,4-g]carbazole-8-carboxamide, CHLORIDE ION, Wee1-like protein kinase | Authors: | Squire, C.J, Dickson, J.M, Ivanovic, I, Baker, E.N. | Deposit date: | 2007-11-29 | Release date: | 2007-12-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Synthesis and structure-activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of the Wee1 and Chk1 checkpoint kinases. Bioorg.Med.Chem.Lett., 18, 2008
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7XDP
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7XDM
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![BU of 7xdm by Molmil](/molmil-images/mine/7xdm) | ChCODH2 A559W mutant in anaerobic condition | Descriptor: | Carbon monoxide dehydrogenase 2, FE(4)-NI(1)-S(5) CLUSTER, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Heo, Y.Y, Kim, S.M. | Deposit date: | 2022-03-28 | Release date: | 2022-10-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | O2-tolerant CO dehydrogenase via tunnel redesign for the removal of CO from industrial flue gas Nat Catal, 5, 2022
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7XDN
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7E3W
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![BU of 7e3w by Molmil](/molmil-images/mine/7e3w) | Metallo beta-lactamase fold protein (cAMP bound) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CHLORIDE ION, ... | Authors: | Lee, K.-Y, Kim, D.-G, Lee, B.-J. | Deposit date: | 2021-02-09 | Release date: | 2022-02-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural and functional studies of SAV1707 from Staphylococcus aureus elucidate its distinct metal-dependent activity and a crucial residue for catalysis. Acta Crystallogr D Struct Biol, 77, 2021
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7E3V
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![BU of 7e3v by Molmil](/molmil-images/mine/7e3v) | Metallo beta-lactamase fold protein (cAMP free) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, NICKEL (II) ION, ... | Authors: | Lee, K.-Y, Kim, D.-G, Lee, B.-J. | Deposit date: | 2021-02-09 | Release date: | 2022-02-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural and functional studies of SAV1707 from Staphylococcus aureus elucidate its distinct metal-dependent activity and a crucial residue for catalysis. Acta Crystallogr D Struct Biol, 77, 2021
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3KAA
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![BU of 3kaa by Molmil](/molmil-images/mine/3kaa) | Structure of Tim-3 in complex with phosphatidylserine | Descriptor: | 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, CALCIUM ION, Hepatitis A virus cellular receptor 2 | Authors: | Ballesteros, A, Santiago, C, Casasnovas, J.M. | Deposit date: | 2009-10-19 | Release date: | 2010-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.002 Å) | Cite: | T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells. J.Immunol., 184, 2010
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6L4G
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2IO6
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![BU of 2io6 by Molmil](/molmil-images/mine/2io6) | Wee1 kinase complexed with inhibitor PD330961 | Descriptor: | 9-HYDROXY-6-(3-HYDROXYPROPYL)-4-(2-METHOXYPHENYL)PYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE, Wee1-like protein kinase | Authors: | Squire, C.J, Dickson, J.M, Ivanovic, I, Baker, E.N. | Deposit date: | 2006-10-10 | Release date: | 2007-09-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases. Eur.J.Med.Chem., 43, 2008
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2IN6
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![BU of 2in6 by Molmil](/molmil-images/mine/2in6) | Wee1 kinase complex with inhibitor PD311839 | Descriptor: | 3-(9-HYDROXY-1,3-DIOXO-4-PHENYL-2,3-DIHYDROPYRROLO[3,4-C]CARBAZOL-6(1H)-YL)PROPANOIC ACID, Wee1-like protein kinase | Authors: | Squire, C.J, Dickson, J.M, Ivanovic, I, Baker, E.N. | Deposit date: | 2006-10-05 | Release date: | 2007-09-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases. Eur.J.Med.Chem., 43, 2008
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2OWY
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7ERR
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![BU of 7err by Molmil](/molmil-images/mine/7err) | |