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5EKX
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BU of 5ekx by Molmil
DENGUE 3 NS5 METHYLTRANSFERASE BOUND TO S-ADENOSYLMETHIONINE AND FRAGMENT NB2E11
Descriptor: 4-chloro-5-methylbenzene-1,2-diamine, NS5 METHYLTRANSFERASE, S-ADENOSYLMETHIONINE
Authors:Barral, K, Bricogne, G, Sharff, A.
Deposit date:2015-11-04
Release date:2016-10-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design.
Eur.J.Med.Chem., 125, 2016
5EHI
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BU of 5ehi by Molmil
DENGUE 3 NS5 METHYLTRANSFERASE BOUND TO S-ADENOSYL METHIONINE AND MOLECULE BF287
Descriptor: 4-[[3-[(2-azanyl-4-chloranyl-phenyl)carbamoylamino]phenyl]sulfonylamino]benzoic acid, NS5 methyltransferase dengue virus, S-ADENOSYLMETHIONINE
Authors:Barral, K, Bricogne, G, Sharff, A.
Deposit date:2015-10-28
Release date:2016-10-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.303 Å)
Cite:Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design.
Eur.J.Med.Chem., 125, 2016
5EIW
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BU of 5eiw by Molmil
DENGUE 3 NS5 METHYLTRANSFERASE BOUND TO S-ADENOSYL METHIONINE AND FRAGMENT NB3C2
Descriptor: 4-(TRIFLUOROMETHYL)BENZENE-1,2-DIAMINE, NS5 methyltransferase, S-ADENOSYLMETHIONINE
Authors:Barral, K, Bricogne, G, Sharff, A.
Deposit date:2015-10-30
Release date:2016-10-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.611 Å)
Cite:Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design.
Eur.J.Med.Chem., 125, 2016
5EC8
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BU of 5ec8 by Molmil
DENGUE 3 NS5 METHYLTRANSFERASE BOUND TO S-ADENOSYL METHIONINE AND COMPOUND BF175
Descriptor: 2-[(2-azanyl-4-chloranyl-phenyl)carbamoylamino]-4-methyl-benzoic acid, Genome polyprotein, S-ADENOSYLMETHIONINE
Authors:Barral, K, Bricogne, G, Sharff, A.
Deposit date:2015-10-20
Release date:2016-10-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.714 Å)
Cite:Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design.
Eur.J.Med.Chem., 125, 2016
8A67
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BU of 8a67 by Molmil
Branched Lys48- and Lys63-linked tri-ubiquitin (K48-K63-Ub3) in complex with matured synthetic nanobody NbSL3.3Q (3rd generation)
Descriptor: CHLORIDE ION, GLYCEROL, ISOPROPYL ALCOHOL, ...
Authors:Lange, S.M, Kulathu, Y.
Deposit date:2022-06-16
Release date:2023-02-15
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:VCP/p97-associated proteins are binders and debranching enzymes of K48-K63-branched ubiquitin chains.
Nat.Struct.Mol.Biol., 2024
7ZFM
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BU of 7zfm by Molmil
Engineered Protein Targeting the Zika Viral Envelope Fusion Loop
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, HEXAETHYLENE GLYCOL, ...
Authors:Athayde, D, Archer, M, Viana, I.F.T, Adan, W.C.S, Xavier, L.S.S, Lins, R.D.
Deposit date:2022-04-01
Release date:2022-08-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.711 Å)
Cite:In Vitro Neutralisation of Zika Virus by an Engineered Protein Targeting the Viral Envelope Fusion Loop
SSRN, 2022
1RNB
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BU of 1rnb by Molmil
CRYSTAL STRUCTURE OF A BARNASE-D(*GP*C) COMPLEX AT 1.9 ANGSTROMS RESOLUTION
Descriptor: BARNASE, DNA (5'-D(*GP*C)-3'), SULFATE ION
Authors:Janin, J, Baudet, S.
Deposit date:1991-03-19
Release date:1992-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a barnase-d(GpC) complex at 1.9 A resolution.
J.Mol.Biol., 219, 1991
1BRS
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BU of 1brs by Molmil
PROTEIN-PROTEIN RECOGNITION: CRYSTAL STRUCTURAL ANALYSIS OF A BARNASE-BARSTAR COMPLEX AT 2.0-A RESOLUTION
Descriptor: BARNASE, BARSTAR
Authors:Buckle, A.M, Schreiber, G, Fersht, A.R.
Deposit date:1994-03-11
Release date:1994-06-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Protein-protein recognition: crystal structural analysis of a barnase-barstar complex at 2.0-A resolution.
Biochemistry, 33, 1994
1BXM
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BU of 1bxm by Molmil
ENGINEERED BETA-CRYPTOGEIN COMPLEXED WITH ERGOSTEROL
Descriptor: BETA-CRYPTOGEIN, ERGOSTEROL
Authors:Boissy, G, Brunie, S.
Deposit date:1998-10-05
Release date:1999-06-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The 2.1 A structure of an elicitin-ergosterol complex: a recent addition to the Sterol Carrier Protein family.
Protein Sci., 8, 1999
1B27
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BU of 1b27 by Molmil
STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE
Descriptor: PROTEIN (BARNASE), PROTEIN (BARSTAR)
Authors:Vaughan, C.K, Buckle, A.M, Fersht, A.R.
Deposit date:1998-12-04
Release date:1998-12-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural response to mutation at a protein-protein interface.
J.Mol.Biol., 286, 1999
1B2U
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BU of 1b2u by Molmil
STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE
Descriptor: PROTEIN (BARNASE), PROTEIN (BARSTAR)
Authors:Vaughan, C.K, Buckle, A.M, Fersht, A.R.
Deposit date:1998-12-01
Release date:1998-12-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural response to mutation at a protein-protein interface.
J.Mol.Biol., 286, 1999
1B3S
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BU of 1b3s by Molmil
STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE
Descriptor: PROTEIN (BARNASE), PROTEIN (BARSTAR)
Authors:Vaughan, C.K, Buckle, A.M, Fersht, A.R.
Deposit date:1998-12-01
Release date:1998-12-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structural response to mutation at a protein-protein interface.
J.Mol.Biol., 286, 1999
1B2S
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BU of 1b2s by Molmil
STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE
Descriptor: PROTEIN (BARNASE), PROTEIN (BARSTAR), SULFATE ION
Authors:Vaughan, C.K, Buckle, A.M, Fersht, A.R.
Deposit date:1998-11-30
Release date:1998-12-08
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structural response to mutation at a protein-protein interface.
J.Mol.Biol., 286, 1999
1BNJ
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BU of 1bnj by Molmil
BARNASE WILDTYPE STRUCTURE AT PH 9.0
Descriptor: BARNASE
Authors:Cameron, A, Henrick, K, Fersht, A.R, Dodson, G, Buckle, A.M.
Deposit date:1995-05-17
Release date:1995-09-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1BNI
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BU of 1bni by Molmil
BARNASE WILDTYPE STRUCTURE AT PH 6.0
Descriptor: BARNASE
Authors:Cameron, A, Henrick, K, Fersht, A.R, Dodson, G, Buckle, A.M.
Deposit date:1995-05-17
Release date:1995-09-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1B21
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BU of 1b21 by Molmil
DELETION OF A BURIED SALT BRIDGE IN BARNASE
Descriptor: PROTEIN (BARNASE), ZINC ION
Authors:Vaughan, C.K, Harryson, P, Buckle, A.M, Oliveberg, M, Fersht, A.R.
Deposit date:1998-12-03
Release date:1998-12-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase.
Acta Crystallogr.,Sect.D, 58, 2002
1BAN
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BU of 1ban by Molmil
THE CONTRIBUTION OF BURIED HYDROGEN BONDS TO PROTEIN STABILITY: THE CRYSTAL STRUCTURES OF TWO BARNASE MUTANTS
Descriptor: BARNASE
Authors:Chen, Y.W, Fersht, A.R, Henrick, K.
Deposit date:1993-05-19
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Contribution of buried hydrogen bonds to protein stability. The crystal structures of two barnase mutants.
J.Mol.Biol., 234, 1993
1B2X
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BU of 1b2x by Molmil
BARNASE WILDTYPE STRUCTURE AT PH 7.5 FROM A CRYO_COOLED CRYSTAL AT 100K
Descriptor: PROTEIN (BARNASE), ZINC ION
Authors:Harrison, P, Vaughan, C.K, Buckle, A.M, Fersht, A.R.
Deposit date:1998-12-03
Release date:1998-12-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase.
Acta Crystallogr.,Sect.D, 58, 2002
1BGS
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BU of 1bgs by Molmil
RECOGNITION BETWEEN A BACTERIAL RIBONUCLEASE, BARNASE, AND ITS NATURAL INHIBITOR, BARSTAR
Descriptor: BARNASE, BARSTAR
Authors:Guillet, V, Lapthorn, A, Mauguen, Y.
Deposit date:1993-11-02
Release date:1994-04-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Recognition between a bacterial ribonuclease, barnase, and its natural inhibitor, barstar.
Structure, 1, 1993
1BNS
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BU of 1bns by Molmil
STRUCTURAL STUDIES OF BARNASE MUTANTS
Descriptor: BARNASE
Authors:Chen, Y.W.
Deposit date:1994-04-11
Release date:1994-06-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Contribution of buried hydrogen bonds to protein stability. The crystal structures of two barnase mutants.
J.Mol.Biol., 234, 1993
1C1M
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BU of 1c1m by Molmil
PORCINE ELASTASE UNDER XENON PRESSURE (8 BAR)
Descriptor: CALCIUM ION, PROTEIN (PORCINE ELASTASE), SULFATE ION, ...
Authors:Prange, T, Schiltz, M, Pernot, L, Colloc'h, N, Longhi, S, Bourguet, W, Fourme, R.
Deposit date:1999-07-22
Release date:1999-07-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Exploring hydrophobic sites in proteins with xenon or krypton.
Proteins, 30, 1998
1BSE
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BU of 1bse by Molmil
CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
Descriptor: BARNASE
Authors:Buckle, A.M, Henrick, K, Fersht, A.R.
Deposit date:1993-07-19
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1BSA
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BU of 1bsa by Molmil
CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
Descriptor: BARNASE
Authors:Buckle, A.M, Henrick, K, Fersht, A.R.
Deposit date:1993-07-19
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1BRG
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BU of 1brg by Molmil
CRYSTALLOGRAPHIC ANALYSIS OF PHE->LEU SUBSTITUTION IN THE HYDROPHOBIC CORE OF BARNASE
Descriptor: BARNASE, ZINC ION
Authors:Chen, Y.W, Fersht, A.R, Henrick, K.
Deposit date:1994-03-30
Release date:1994-06-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic analysis of Phe-->Leu substitution in the hydrophobic core of barnase.
Acta Crystallogr.,Sect.D, 51, 1995
1BSB
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BU of 1bsb by Molmil
CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
Descriptor: BARNASE
Authors:Buckle, A.M, Henrick, K, Fersht, A.R.
Deposit date:1993-07-19
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993

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