2Z5V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2z5v by Molmil](/molmil-images/mine/2z5v) | Solution structure of the TIR domain of human MyD88 | Descriptor: | Myeloid differentiation primary response protein MyD88 | Authors: | Ohnishi, H, Tochio, H, Hiroaki, H, Kondo, N, Kato, Z, Shirakawa, M. | Deposit date: | 2007-07-19 | Release date: | 2008-08-05 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling. Proc.Natl.Acad.Sci.USA, 2009
|
|
6BY9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6by9 by Molmil](/molmil-images/mine/6by9) | Crystal structure of EHMT1 | Descriptor: | Histone-lysine N-methyltransferase EHMT1, UNKNOWN ATOM OR ION | Authors: | Dong, A, Wei, Y, Li, A, Tempel, W, Han, S, Sunnerhagen, M, Penn, L, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | Deposit date: | 2017-12-20 | Release date: | 2018-01-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of EHMT1 to be published
|
|
3G4D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3g4d by Molmil](/molmil-images/mine/3g4d) | Crystal Structure of (+)-delta-Cadinene Synthase from Gossypium arboreum and Evolutionary Divergence of Metal Binding Motifs for Catalysis | Descriptor: | (+)-delta-cadinene synthase isozyme XC1, BETA-MERCAPTOETHANOL, GLYCEROL | Authors: | Gennadios, H.A, Di Costanzo, L, Miller, D.J, Allemann, R.K, Christianson, D.W. | Deposit date: | 2009-02-03 | Release date: | 2009-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | Crystal structure of (+)-delta-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysis. Biochemistry, 48, 2009
|
|
3G4F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3g4f by Molmil](/molmil-images/mine/3g4f) | Crystal Structure of (+)- -Cadinene Synthase from Gossypium arboreum in complex with 2-fluorofarnesyl diphosphate | Descriptor: | (+)-delta-cadinene synthase isozyme XC1, (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, BETA-MERCAPTOETHANOL, ... | Authors: | Gennadios, H.A, Di Costanzo, L, Christianson, D.W. | Deposit date: | 2009-02-03 | Release date: | 2009-06-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.651 Å) | Cite: | Crystal structure of (+)-delta-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysis. Biochemistry, 48, 2009
|
|
4EED
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4eed by Molmil](/molmil-images/mine/4eed) | CorA coiled-coil mutant under Mg2+ presence | Descriptor: | MAGNESIUM ION, Magnesium transport protein CorA | Authors: | Pfoh, R, Pai, E.F. | Deposit date: | 2012-03-28 | Release date: | 2012-11-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.92 Å) | Cite: | Structural asymmetry in the magnesium channel CorA points to sequential allosteric regulation. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
4EEB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4eeb by Molmil](/molmil-images/mine/4eeb) | CorA coiled-coil mutant under Mg2+ absence | Descriptor: | CESIUM ION, Magnesium transport protein CorA, SODIUM ION | Authors: | Pfoh, R, Pai, E.F. | Deposit date: | 2012-03-28 | Release date: | 2012-11-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural asymmetry in the magnesium channel CorA points to sequential allosteric regulation. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
8H6Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8h6q by Molmil](/molmil-images/mine/8h6q) | Class I sesquiterpene synthase BCBOT2 (apo) | Descriptor: | Presilphiperfolan-8-beta-ol synthase | Authors: | Lou, T.T, Ma, M. | Deposit date: | 2022-10-18 | Release date: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Insights into Three Sesquiterpene Synthases for the Biosynthesis of Tricyclic Sesquiterpenes and Chemical Space Expansion by Structure-Based Mutagenesis. J.Am.Chem.Soc., 2023
|
|
8H6U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8h6u by Molmil](/molmil-images/mine/8h6u) | Class I sesquiterpene synthase BCBOT2 (complex) | Descriptor: | MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, PYROPHOSPHATE 2-, ... | Authors: | Lou, T.T, Ma, M. | Deposit date: | 2022-10-18 | Release date: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Structural Insights into Three Sesquiterpene Synthases for the Biosynthesis of Tricyclic Sesquiterpenes and Chemical Space Expansion by Structure-Based Mutagenesis. J.Am.Chem.Soc., 2023
|
|
8H72
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8h72 by Molmil](/molmil-images/mine/8h72) | Class I sesquiterpene synthase DbPROS (complex) | Descriptor: | Delta(6)-protoilludene synthase K435DRAFT_659367, MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium | Authors: | Lou, T.T, Ma, M. | Deposit date: | 2022-10-18 | Release date: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Structural Insights into Three Sesquiterpene Synthases for the Biosynthesis of Tricyclic Sesquiterpenes and Chemical Space Expansion by Structure-Based Mutagenesis. J.Am.Chem.Soc., 2023
|
|
7KSA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ksa by Molmil](/molmil-images/mine/7ksa) | Crystal structure of human CYP3A4 with the caged inhibitor | Descriptor: | (tert-butyl {1-[(1-oxo-3-phenyl-1-{[3-(pyridin-3-yl-kappaN)prop-1-en-1-yl]amino}propan-2-yl)sulfanyl]-3-phenylpropan-2-yl}carbamate)(6,6'-dimethyl-2,2'-bipyridine-kappa~2~N~1~,N~1'~)(1~2~,2~2~:2~6~,3~2~-terpyridine-kappa~3~N~1^{1~},N~2^{1~},N~3^{1~})ruthenium, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Sevrioukova, I.S. | Deposit date: | 2020-11-21 | Release date: | 2021-06-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Photosensitive Ru(II) Complexes as Inhibitors of the Major Human Drug Metabolizing Enzyme CYP3A4. J.Am.Chem.Soc., 143, 2021
|
|
7KS8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ks8 by Molmil](/molmil-images/mine/7ks8) | Crystal structure of human CYP3A4 with the caged inhibitor | Descriptor: | (tert-butyl {1-[(3-oxo-3-{[(pyridin-3-yl-kappaN)methyl]amino}propyl)sulfanyl]-3-phenylpropan-2-yl}carbamate)(6,6'-dimethyl-2,2'-bipyridine-kappa~2~N~1~,N~1'~)(1~2~,2~2~:2~6~,3~2~-terpyridine-kappa~3~N~1^{1~},N~2^{1~},N~3^{1~})ruthenium, Cytochrome P450 3A4, GLYCEROL, ... | Authors: | Sevrioukova, I.S. | Deposit date: | 2020-11-21 | Release date: | 2021-06-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Photosensitive Ru(II) Complexes as Inhibitors of the Major Human Drug Metabolizing Enzyme CYP3A4. J.Am.Chem.Soc., 143, 2021
|
|
7XZJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xzj by Molmil](/molmil-images/mine/7xzj) | Cryo-EM structure of TOC complex from Chlamydomonas reinhardtii. | Descriptor: | Ctap3, INOSITOL HEXAKISPHOSPHATE, Tic100, ... | Authors: | Liu, H, Li, A.J, Liu, Z.F. | Deposit date: | 2022-06-02 | Release date: | 2023-01-11 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Architecture of chloroplast TOC-TIC translocon supercomplex. Nature, 615, 2023
|
|
7XZI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xzi by Molmil](/molmil-images/mine/7xzi) | Cryo-EM structure of TOC-TIC supercomplex from Chlamydomonas reinhardtii | Descriptor: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, Ctap3, ... | Authors: | Liu, H, Li, A.J, Liu, Z.F. | Deposit date: | 2022-06-02 | Release date: | 2023-01-11 | Last modified: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | Architecture of chloroplast TOC-TIC translocon supercomplex. Nature, 615, 2023
|
|
5ZOL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zol by Molmil](/molmil-images/mine/5zol) | Crystal structure of a three sites mutantion of FSAA complexed with HA and product | Descriptor: | (3S,4S)-3,4-dihydroxy-4-(thiophen-2-yl)butan-2-one, 1-hydroxypropan-2-one, CHLORIDE ION, ... | Authors: | Wu, L, Yang, X.H, Yu, H.W, Zhou, J.H. | Deposit date: | 2018-04-13 | Release date: | 2019-06-12 | Last modified: | 2020-07-22 | Method: | X-RAY DIFFRACTION (2.172 Å) | Cite: | The engineering of decameric d-fructose-6-phosphate aldolase A by combinatorial modulation of inter- and intra-subunit interactions. Chem.Commun.(Camb.), 56, 2020
|
|
7E4M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e4m by Molmil](/molmil-images/mine/7e4m) | |
7E4O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e4o by Molmil](/molmil-images/mine/7e4o) | |
7E4N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e4n by Molmil](/molmil-images/mine/7e4n) | Crystal structure of Sat1646 | Descriptor: | MAGNESIUM ION, Sat1646 | Authors: | Yu, J.H, Xing, B.Y, Ma, M. | Deposit date: | 2021-02-14 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Functional characterization and structural bases of two class I diterpene synthases in pimarane-type diterpene biosynthesis Commun Chem, 4, 2021
|
|
6II9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ii9 by Molmil](/molmil-images/mine/6ii9) | Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a human neutralizing antibody L3A-44 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of L3A-44 Fab, Hemagglutinin, ... | Authors: | Jiang, H.H, Shi, Y, Qi, J, Gao, G.F. | Deposit date: | 2018-10-03 | Release date: | 2018-10-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans. Nat Microbiol, 4, 2019
|
|
6K2U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6k2u by Molmil](/molmil-images/mine/6k2u) | Crystal structure of Thr66 ADP-ribosylated ubiquitin | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, MAGNESIUM ION, Polyubiquitin-C, ... | Authors: | Wang, X, Zhou, Y, Zhu, Y. | Deposit date: | 2019-05-15 | Release date: | 2020-03-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.554 Å) | Cite: | Threonine ADP-Ribosylation of Ubiquitin by a Bacterial Effector Family Blocks Host Ubiquitination. Mol.Cell, 78, 2020
|
|
6II8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ii8 by Molmil](/molmil-images/mine/6ii8) | Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a human neutralizing antibody L4B-18 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of L4B-18 Fab, Hemagglutinin, ... | Authors: | Jiang, H.H, Shi, Y, Qi, J, Gao, G.F. | Deposit date: | 2018-10-03 | Release date: | 2018-10-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.32 Å) | Cite: | Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans. Nat Microbiol, 4, 2019
|
|
6II4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ii4 by Molmil](/molmil-images/mine/6ii4) | Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a human neutralizing antibody L4A-14 | Descriptor: | Heavy chain of L4A-14 Fab, Hemagglutinin, Light chain of L4A-14 Fab | Authors: | Jiang, H.H, Shi, Y, Qi, J, Gao, G.F. | Deposit date: | 2018-10-03 | Release date: | 2018-10-24 | Last modified: | 2019-02-06 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans. Nat Microbiol, 4, 2019
|
|
7Y50
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7y50 by Molmil](/molmil-images/mine/7y50) | Class I diterpene synthase (CyS) from Streptomyces cattleya | Descriptor: | Putative glutamate dehydrogenase/leucine dehydrogenase | Authors: | Xing, B, Ma, M. | Deposit date: | 2022-06-16 | Release date: | 2022-12-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure Based Mutagenesis of Cattleyene Synthase Leads to the Generation of Rearranged Polycyclic Diterpenes. Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
7Y87
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7y87 by Molmil](/molmil-images/mine/7y87) | |
7Y88
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7y88 by Molmil](/molmil-images/mine/7y88) | class I diterpene synthase (CyS-GGPP-Mg2+) from Streptomyces cattleya | Descriptor: | GERANYLGERANYL DIPHOSPHATE, MAGNESIUM ION, Putative glutamate dehydrogenase/leucine dehydrogenase | Authors: | Xing, B, Ma, M. | Deposit date: | 2022-06-23 | Release date: | 2022-12-21 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Crystal Structure Based Mutagenesis of Cattleyene Synthase Leads to the Generation of Rearranged Polycyclic Diterpenes. Angew.Chem.Int.Ed.Engl., 61, 2022
|
|