1NZJ
 
 | | Crystal Structure and Activity Studies of Escherichia Coli Yadb ORF | | Descriptor: | Hypothetical protein yadB, ZINC ION | | Authors: | Campanacci, V, Kern, D.Y, Becker, H.D, Spinelli, S, Valencia, C, Vincentelli, R, Pagot, F, Bignon, C, Giege, R, Cambillau, C. | | Deposit date: | 2003-02-18 | | Release date: | 2004-04-13 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The Escherichia coli YadB gene product reveals a novel aminoacyl-tRNA synthetase like activity.
J.Mol.Biol., 337, 2004
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5WC7
 | | CypA Mutant - I97V S99T C115S | | Descriptor: | Peptidyl-prolyl cis-trans isomerase A | | Authors: | Fraser, J.S. | | Deposit date: | 2017-06-29 | | Release date: | 2018-04-18 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.43 Å) | | Cite: | Rescue of conformational dynamics in enzyme catalysis by directed evolution.
Nat Commun, 9, 2018
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1B76
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1GGM
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3K0M
 | | Cryogenic structure of CypA | | Descriptor: | Cyclophilin A | | Authors: | Fraser, J.S, Alber, T. | | Deposit date: | 2009-09-24 | | Release date: | 2009-12-08 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Hidden alternative structures of proline isomerase essential for catalysis.
Nature, 462, 2009
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3K0R
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3K0N
 | | Room temperature structure of CypA | | Descriptor: | Cyclophilin A | | Authors: | Fraser, J.S, Alber, T. | | Deposit date: | 2009-09-24 | | Release date: | 2009-12-08 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.391 Å) | | Cite: | Hidden alternative structures of proline isomerase essential for catalysis.
Nature, 462, 2009
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3K0Q
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3K0O
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1GPU
 | | Transketolase complex with reaction intermediate | | Descriptor: | 2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, CALCIUM ION, TRANSKETOLASE 1 | | Authors: | Fiedler, E, Thorell, S, Sandalova, T, Koenig, S, Schneider, G. | | Deposit date: | 2001-11-09 | | Release date: | 2002-02-11 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Snapshot of a Key Intermediate in Enzymatic Thiamin Catalysis: Crystal Structure of the Alpha-Carbanion of (Alpha,Beta-Dihydroxyethyl)-Thiamin Diphosphate in the Active Site of Transketolase from Saccharomyces Cerevisiae.
Proc.Natl.Acad.Sci.USA, 99, 2002
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9MUT
 | | Reduced state of a turn-on thiol-disulfide redox biosensor with a fluorescence-lifetime readout | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, FORMIC ACID, ... | | Authors: | Rosen, P, Yellen, G, Lim, D.C. | | Deposit date: | 2025-01-14 | | Release date: | 2025-06-18 | | Last modified: | 2025-06-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Mechanism and application of thiol-disulfide redox biosensors with a fluorescence-lifetime readout.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9MUV
 | | Oxidized state of a turn-on thiol-disulfide redox biosensor with a fluorescence-lifetime readout | | Descriptor: | ACETIC ACID, DI(HYDROXYETHYL)ETHER, Fluorescent thiol-disulfide redox biosensor, ... | | Authors: | Rosen, P, Yellen, G, Lim, D.C. | | Deposit date: | 2025-01-14 | | Release date: | 2025-06-18 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Mechanism and application of thiol-disulfide redox biosensors with a fluorescence-lifetime readout.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9MUU
 | | Oxidized state of a turn-off thiol-disulfide redox biosensor with a fluorescence-lifetime readout | | Descriptor: | ACETATE ION, FORMIC ACID, Fluorescent thiol-disulfide redox biosensor, ... | | Authors: | Rosen, P, Yellen, G, Lim, D.C. | | Deposit date: | 2025-01-14 | | Release date: | 2025-06-18 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Mechanism and application of thiol-disulfide redox biosensors with a fluorescence-lifetime readout.
Proc.Natl.Acad.Sci.USA, 122, 2025
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9MUS
 | | Reduced state of a turn-off thiol-disulfide redox biosensor with a fluorescence-lifetime readout | | Descriptor: | ACETIC ACID, Fluorescent thiol-disulfide redox biosensor, GLYCEROL, ... | | Authors: | Rosen, P, Yellen, G, Lim, D.C. | | Deposit date: | 2025-01-14 | | Release date: | 2025-06-18 | | Last modified: | 2025-06-25 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Mechanism and application of thiol-disulfide redox biosensors with a fluorescence-lifetime readout.
Proc.Natl.Acad.Sci.USA, 122, 2025
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3K0P
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2OSE
 | | Crystal Structure of the Mimivirus Cyclophilin | | Descriptor: | CHLORIDE ION, Probable peptidyl-prolyl cis-trans isomerase | | Authors: | Eisenmesser, E.Z, Thai, V, Renesto, P, Raoult, D. | | Deposit date: | 2007-02-05 | | Release date: | 2007-12-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Structural, biochemical, and in vivo characterization of the first virally encoded cyclophilin from the Mimivirus.
J.Mol.Biol., 378, 2008
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4M2O
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4MLW
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4M2P
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6BTA
 | | CypA Mutant - S99T C115S | | Descriptor: | Peptidyl-prolyl cis-trans isomerase A | | Authors: | Fraser, J.S, Kenner, L.R, Liu, L. | | Deposit date: | 2017-12-06 | | Release date: | 2018-04-18 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Rescue of conformational dynamics in enzyme catalysis by directed evolution.
Nat Commun, 9, 2018
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1EOV
 | | FREE ASPARTYL-TRNA SYNTHETASE (ASPRS) (E.C. 6.1.1.12) FROM YEAST | | Descriptor: | ASPARTYL-TRNA SYNTHETASE | | Authors: | Sauter, C, Lorber, B, Cavarelli, J, Moras, D, Giege, R. | | Deposit date: | 2000-03-24 | | Release date: | 2000-09-24 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The free yeast aspartyl-tRNA synthetase differs from the tRNA(Asp)-complexed enzyme by structural changes in the catalytic site, hinge region, and anticodon-binding domain.
J.Mol.Biol., 299, 2000
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9EFG
 | | VIP3Cb1 Toxin structure | | Descriptor: | MAGNESIUM ION, VIP3Cb1 Toxin | | Authors: | Rau, M.J, Rydel, T, Zheng, M, White, T. | | Deposit date: | 2024-11-20 | | Release date: | 2025-06-18 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Vip3C proteins from Paenibacillus spp. for controlling lepidopteran crop pests.
Appl.Environ.Microbiol., 2025
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9EFI
 | | VIP3Cb1 Protoxin Structure | | Descriptor: | VIP3Cb1 Protoxin Structure - Disable Toxin Variant | | Authors: | Rau, M.J, Rydel, T, Zheng, M, White, T. | | Deposit date: | 2024-11-20 | | Release date: | 2025-06-18 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Vip3C proteins from Paenibacillus spp. for controlling lepidopteran crop pests.
Appl.Environ.Microbiol., 2025
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