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1QLU
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BU of 1qlu by Molmil
STRUCTURE OF THE H422A MUTANT VANILLYL-ALCOHOL OXIDASE IN COMPLEX WITH ISOEUGENOL
Descriptor: 2-methoxy-4-[(1E)-prop-1-en-1-yl]phenol, FLAVIN-ADENINE DINUCLEOTIDE, VANILLYL-ALCOHOL OXIDASE
Authors:Mattevi, A.
Deposit date:1999-09-16
Release date:1999-09-20
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Covalent Flavinylation is Essential for Efficient Redox Catalysis in Vanillyl-Alcohol Oxidase
J.Biol.Chem., 274, 1999
4UDP
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BU of 4udp by Molmil
Crystal structure of 5-hydroxymethylfurfural oxidase (HMFO) in the oxidized state
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE
Authors:Dijkman, W, Binda, C, Fraaije, M, Mattevi, A.
Deposit date:2014-12-11
Release date:2015-03-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-Based Enzyme Tailoring of 5-Hydroxymethylfurfural Oxidase
Acs Catalysis, 5, 2015
4UDR
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BU of 4udr by Molmil
Crystal structure of the H467A mutant of 5-hydroxymethylfurfural oxidase (HMFO)
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE
Authors:Dijkman, W, Binda, C, Fraaije, M, Mattevi, A.
Deposit date:2014-12-11
Release date:2015-03-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure-Based Enzyme Tailoring of 5-Hydroxymethylfurfural Oxidase
Acs Catalysis, 5, 2015
4UDQ
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BU of 4udq by Molmil
Crystal structure of 5-hydroxymethylfurfural oxidase (HMFO) in the reduced state
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE
Authors:Dijkman, W, Binda, C, Fraaije, M, Mattevi, A.
Deposit date:2014-12-11
Release date:2015-03-18
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure-Based Enzyme Tailoring of 5-Hydroxymethylfurfural Oxidase
Acs Catalysis, 5, 2015
1W4X
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BU of 1w4x by Molmil
Phenylacetone Monooxygenase, a Baeyer-Villiger Monooxygenase
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, PHENYLACETONE MONOOXYGENASE, SULFATE ION
Authors:Malito, E, Alfieri, A, Mattevi, A.
Deposit date:2004-08-03
Release date:2004-09-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of a Baeyer-Villiger Monooxygenase
Proc.Natl.Acad.Sci.USA, 101, 2004
7YWV
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BU of 7ywv by Molmil
Eugenol oxidase from rhodococcus jostii: mutant S81H, D151E, A423M, H434Y, S394V, Q425S, I445D, S518P
Descriptor: 2-methoxy-4-(prop-2-en-1-yl)phenol, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Alvigini, L, Mattevi, A.
Deposit date:2022-02-14
Release date:2022-11-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure- and computational-aided engineering of an oxidase to produce isoeugenol from a lignin-derived compound.
Nat Commun, 13, 2022
7YWU
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BU of 7ywu by Molmil
Eugenol oxidase from rhodococcus jostii: mutant S81H, A423M, H434Y, S394V, I445D, S518P
Descriptor: 2-methoxy-4-(prop-2-en-1-yl)phenol, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Alvigini, L, Mattevi, A.
Deposit date:2022-02-14
Release date:2022-11-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure- and computational-aided engineering of an oxidase to produce isoeugenol from a lignin-derived compound.
Nat Commun, 13, 2022
6SEM
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BU of 6sem by Molmil
Crystal Structure of Ancestral Flavin-containing monooxygenase (FMO) 2
Descriptor: Ancestral Flavin-containing monooxygenase (FMO) 2, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Nicoll, C, Bailleul, G, Fiorentini, F, Mascotti, M.L, Fraaije, M, Mattevi, A.
Deposit date:2019-07-30
Release date:2019-12-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs.
Nat.Struct.Mol.Biol., 27, 2020
6SF0
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BU of 6sf0 by Molmil
Crystal Structure of Ancestral Flavin-containing monooxygenase (FMO) 2 in the presence of NADP+
Descriptor: Ancestral Flavin-containing monooxygenase (FMO) 2, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Nicoll, C, Bailleul, G, Fiorentini, F, Mascotti, M.L, Fraaije, M, Mattevi, A.
Deposit date:2019-07-30
Release date:2019-12-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs.
Nat.Struct.Mol.Biol., 27, 2020
6SEK
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BU of 6sek by Molmil
Crystal Structure of Ancestral Flavin-containing monooxygenase (FMO) 5
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Ancestral Flavin-containing monooxygenase 5, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Nicoll, C, Bailleul, G, Fiorentini, F, Mascotti, M.L, Fraaije, M, Mattevi, A.
Deposit date:2019-07-30
Release date:2019-12-25
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs.
Nat.Struct.Mol.Biol., 27, 2020
6SE3
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BU of 6se3 by Molmil
Crystal Structure of Ancestral Flavin-containing monooxygenase (FMO) 3-6
Descriptor: Ancestral Flavin-containing monooxygenase (FMO) 3-6, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Nicoll, C, Bailleul, G, Fiorentini, F, Mascotti, M.L, Fraaije, M, Mattevi, A.
Deposit date:2019-07-29
Release date:2019-12-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs.
Nat.Struct.Mol.Biol., 27, 2020
8CP5
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BU of 8cp5 by Molmil
Structure of Aspartate-N-hydroxylase (FzmM)from Streptomyces sp. V2: complex with NADPH and Sulphate
Descriptor: DI(HYDROXYETHYL)ETHER, FAD-binding protein, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Rotilio, L, Mattevi, A.
Deposit date:2023-03-01
Release date:2023-07-12
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:A biosynthetic aspartate N-hydroxylase performs successive oxidations by holding intermediates at a site away from the catalytic center.
J.Biol.Chem., 299, 2023
8CP2
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BU of 8cp2 by Molmil
Structure of Aspartate-N-hydroxylase (FzmM)from Streptomyces sp. V2: complex with NADPH and L-aspartate
Descriptor: 3-NITROPROPANOIC ACID, ASPARTIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Rotilio, L, Mattevi, A.
Deposit date:2023-03-01
Release date:2023-07-12
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A biosynthetic aspartate N-hydroxylase performs successive oxidations by holding intermediates at a site away from the catalytic center.
J.Biol.Chem., 299, 2023
6HNS
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BU of 6hns by Molmil
Structure of Nitrincola lacisaponensis flavin-containing monooxygenase (FMO) in complex with FAD and NADP+
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Fiorentini, F, Mattevi, A.
Deposit date:2018-09-17
Release date:2019-01-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Characterization of a thermostable flavin-containing monooxygenase from Nitrincola lacisaponensis (NiFMO).
Appl. Microbiol. Biotechnol., 103, 2019
7AL4
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BU of 7al4 by Molmil
Ancestral Flavin-containing monooxygenase (FMO) 1 (mammalian)
Descriptor: Ancestral Flavin-containing monooxygenase 1 (mammalian), CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Nicoll, C.R, Mattevi, A.
Deposit date:2020-10-05
Release date:2020-12-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:Ancestral reconstruction of mammalian FMO1 enables structural determination, revealing unique features that explain its catalytic properties.
J.Biol.Chem., 296, 2020
5O0X
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BU of 5o0x by Molmil
Crystal structure of dehydrogenase domain of Cylindrospermum stagnale NADPH-Oxidase 5 (NOX5)
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Magnani, F, Nenci, S, Mattevi, A.
Deposit date:2017-05-17
Release date:2017-06-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures and atomic model of NADPH oxidase.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5O0T
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BU of 5o0t by Molmil
CRYSTAL STRUCTURE OF TRANS-MEMBRANE DOMAIN OF Cylindrospermum stagnale NADPH-OXIDASE 5 (NOX5)
Descriptor: DECANE, DI(HYDROXYETHYL)ETHER, EICOSANE, ...
Authors:Magnani, F, Nenci, S, Mattevi, A.
Deposit date:2017-05-17
Release date:2017-06-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures and atomic model of NADPH oxidase.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8OT8
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BU of 8ot8 by Molmil
Alditol oxidase from Actinomycetota bacterium in complex with D-xylulose
Descriptor: D-XYLULOSE, FAD-binding protein, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Rotilio, L, Mattevi, A.
Deposit date:2023-04-20
Release date:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery and biochemical characterization of thermostable glycerol oxidases.
Appl.Microbiol.Biotechnol., 108, 2024
7PBG
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BU of 7pbg by Molmil
4-ethylphenol oxidase from Gulosibacter chungangensis: native structure
Descriptor: CHLORIDE ION, FAD-binding oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Alvigini, L, Mattevi, A.
Deposit date:2021-08-02
Release date:2021-09-29
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Discovery, Biocatalytic Exploration and Structural Analysis of a 4-Ethylphenol Oxidase from Gulosibacter chungangensis.
Chembiochem, 22, 2021
7PBI
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BU of 7pbi by Molmil
4-ethylphenol oxidase from Gulosibacter chungangensis: isoeugenol complex
Descriptor: FAD-binding oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE, ISOEUGENOL
Authors:Alvigini, L, Mattevi, A.
Deposit date:2021-08-02
Release date:2021-09-29
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery, Biocatalytic Exploration and Structural Analysis of a 4-Ethylphenol Oxidase from Gulosibacter chungangensis.
Chembiochem, 22, 2021
6GQI
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BU of 6gqi by Molmil
Thermocrispum municipale cyclohexanone monooxygenase bound to hexanoic acid
Descriptor: ACETATE ION, Cyclohexanone Monooxygenase from Thermocrispum municipale, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Mattevi, A, Gomez Castellanos, J.R.
Deposit date:2018-06-07
Release date:2018-12-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Side-Chain Pruning Has Limited Impact on Substrate Preference in a Promiscuous Enzyme.
ACS Catal, 8, 2018
8BAM
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BU of 8bam by Molmil
Eugenol Oxidase (EUGO) from Rhodococcus jostii RHA1, tenfold mutant active on propanol syringol
Descriptor: 2,6-dimethoxy-4-(3-oxidanylpropyl)phenol, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Alvigini, L, Mattevi, A.
Deposit date:2022-10-11
Release date:2023-10-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:One-Pot Biocatalytic Synthesis of rac -Syringaresinol from a Lignin-Derived Phenol.
Acs Catalysis, 13, 2023
8BAP
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BU of 8bap by Molmil
Eugenol Oxidase (EUGO) from Rhodococcus jostii RHA1, eightfold mutant active on propanol syringol
Descriptor: 4-[(1E)-3-hydroxyprop-1-en-1-yl]-2,6-dimethoxyphenol, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Alvigini, L, Mattevi, A.
Deposit date:2022-10-11
Release date:2023-10-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:One-Pot Biocatalytic Synthesis of rac -Syringaresinol from a Lignin-Derived Phenol.
Acs Catalysis, 13, 2023
5M10
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BU of 5m10 by Molmil
Crystal structure of cyclohexanone monooxygenase from Thermocrispum municipale in the oxidised state with a bound nicotinamide.
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cyclohexanone Monooxygenase from Thermocrispum municipale, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Gomez-Castellanos, J.R, Mattevi, A.
Deposit date:2016-10-06
Release date:2016-12-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:Characterization and Crystal Structure of a Robust Cyclohexanone Monooxygenase.
Angew. Chem. Int. Ed. Engl., 55, 2016
5M0Z
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BU of 5m0z by Molmil
Cyclohexanone Monooxygenase from T. municipale: reduced enzyme bound to NADP+
Descriptor: Cyclohexanone Monooxygenase from Thermocrispum municipale., FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Gomez-Castellanos, J.R, Mattevi, A.
Deposit date:2016-10-06
Release date:2016-12-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Characterization and Crystal Structure of a Robust Cyclohexanone Monooxygenase.
Angew. Chem. Int. Ed. Engl., 55, 2016

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