8S45
 
 | | CdaA-E05 complex | | Descriptor: | (1~{R},2~{S},3~{S},4~{R},5~{S})-2-azanyl-4-phenylsulfanyl-6,8-dioxabicyclo[3.2.1]octan-3-ol, Diadenylate cyclase | | Authors: | Neumann, P, Ficner, R. | | Deposit date: | 2024-02-21 | | Release date: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | CdaA-E05 complex
To Be Published
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8S47
 | | CdaA-D07 complex | | Descriptor: | CHLORIDE ION, Diadenylate cyclase, N-(pyridin-2-yl)-2-(1,3,5-trimethyl-1H-pyrazol-4-yl)acetamide | | Authors: | Neumann, P, Ficner, R. | | Deposit date: | 2024-02-21 | | Release date: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | CdaA-D07 complex
To Be Published
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8S4A
 | | CdaA-B04 complex | | Descriptor: | 2-[cyanomethyl(methyl)amino]-N-(6-methylpyridin-2-yl)ethanamide, CHLORIDE ION, Diadenylate cyclase | | Authors: | Neumann, P, Ficner, R. | | Deposit date: | 2024-02-21 | | Release date: | 2024-06-19 | | Last modified: | 2024-07-03 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | CdaA-B04 complex
To Be Published
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8S46
 | | CdaA-E01 complex | | Descriptor: | 2-chlorobenzyl carbamimidothioate, Diadenylate cyclase, SODIUM ION | | Authors: | Neumann, P, Ficner, R. | | Deposit date: | 2024-02-21 | | Release date: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | CdaA-E01 complex
To Be Published
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8S4B
 | | CdaA-C08 complex | | Descriptor: | (4-methoxycarbonylphenyl)methylazanium, Diadenylate cyclase | | Authors: | Neumann, P, Ficner, R. | | Deposit date: | 2024-02-21 | | Release date: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | CdaA-C08 complex
To Be Published
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8S4C
 | | CdaA-H04 complex | | Descriptor: | DAMINOZIDE, Diadenylate cyclase | | Authors: | Neumann, P, Ficner, R. | | Deposit date: | 2024-02-21 | | Release date: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | CdaA-H04 complex
To Be Published
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8S48
 | | CdaA-C11 complex | | Descriptor: | 2-(1H-indol-3-yl)-N-[(1-methyl-1H-pyrrol-2-yl)methyl]ethanamine, Diadenylate cyclase | | Authors: | Neumann, P, Ficner, R. | | Deposit date: | 2024-02-21 | | Release date: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | CdaA-C11 complex
To Be Published
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6TVO
 | | Human CRM1-RanGTP in complex with Leptomycin B | | Descriptor: | Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Shaikhqasem, A, Ficner, R. | | Deposit date: | 2020-01-10 | | Release date: | 2020-07-08 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.201 Å) | | Cite: | Characterization of Inhibition Reveals Distinctive Properties for Human andSaccharomyces cerevisiaeCRM1.
J.Med.Chem., 63, 2020
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6I3P
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6HVN
 | | CdaA-APO Y187A Mutant | | Descriptor: | CHLORIDE ION, Diadenylate cyclase, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | | Authors: | Heidemann, J.L, Neumann, P, Ficner, R. | | Deposit date: | 2018-10-11 | | Release date: | 2019-06-05 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.234 Å) | | Cite: | Crystal structures of the c-di-AMP-synthesizing enzyme CdaA.
J.Biol.Chem., 294, 2019
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6HVM
 | | Structural characterization of CdaA-APO | | Descriptor: | CHLORIDE ION, Diadenylate cyclase, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | | Authors: | Heidemann, J.L, Neumann, P, Ficner, R. | | Deposit date: | 2018-10-11 | | Release date: | 2019-06-05 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of the c-di-AMP-synthesizing enzyme CdaA.
J.Biol.Chem., 294, 2019
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6HVL
 | | CdaA complex with c-di-AMP and AMP | | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, ADENOSINE MONOPHOSPHATE, COBALT (II) ION, ... | | Authors: | Heidemann, J.L, Neumann, P, Ficner, R. | | Deposit date: | 2018-10-11 | | Release date: | 2019-06-05 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structures of the c-di-AMP-synthesizing enzyme CdaA.
J.Biol.Chem., 294, 2019
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6I3O
 | | Crystal structure of DEAH-box ATPase Prp22 | | Descriptor: | Putative pre-mRNA splicing factor | | Authors: | Hamann, F, Ficner, R. | | Deposit date: | 2018-11-07 | | Release date: | 2019-03-06 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | Structural basis for RNA translocation by DEAH-box ATPases.
Nucleic Acids Res., 47, 2019
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6F2C
 | | Methylglyoxal synthase MgsA from Bacillus subtilis | | Descriptor: | CHLORIDE ION, GLYCEROL, Methylglyoxal synthase | | Authors: | Dickmanns, A, Neumann, P, Ficner, R. | | Deposit date: | 2017-11-24 | | Release date: | 2018-03-07 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Structural basis for the regulatory interaction of the methylglyoxal synthase MgsA with the carbon flux regulator Crh inBacillus subtilis.
J. Biol. Chem., 293, 2018
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5O5S
 | | X-ray crystal structure of the RapZ C-terminal domain from Escherichia coli | | Descriptor: | MALONATE ION, RNase adapter protein RapZ | | Authors: | Gonzalez, G.M, Durica-Mitic, S, Hardwick, S.W, Moncrieffe, M, Resch, M, Neumann, P, Ficner, R, Gorke, B, Luisi, B.F. | | Deposit date: | 2017-06-02 | | Release date: | 2017-08-30 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.17 Å) | | Cite: | Structural insights into RapZ-mediated regulation of bacterial amino-sugar metabolism.
Nucleic Acids Res., 45, 2017
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5O5O
 | | X-ray crystal structure of RapZ from Escherichia coli (P32 space group) | | Descriptor: | RNase adapter protein RapZ, SULFATE ION | | Authors: | Gonzalez, G.M, Durica-Mitic, S, Hardwick, S.W, Moncrieffe, M, Resch, M, Neumann, P, Ficner, R, Gorke, B, Luisi, B.F. | | Deposit date: | 2017-06-02 | | Release date: | 2017-08-30 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (3.404 Å) | | Cite: | Structural insights into RapZ-mediated regulation of bacterial amino-sugar metabolism.
Nucleic Acids Res., 45, 2017
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5O5Q
 | | X-ray crystal structure of RapZ from Escherichia coli (P3221 space group) | | Descriptor: | RNase adapter protein RapZ, SULFATE ION | | Authors: | Gonzalez, G.M, Durica-Mitic, S, Hardwick, S.W, Moncrieffe, M, Resch, M, Neumann, P, Ficner, R, Gorke, B, Luisi, B.F. | | Deposit date: | 2017-06-02 | | Release date: | 2017-08-30 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | Structural insights into RapZ-mediated regulation of bacterial amino-sugar metabolism.
Nucleic Acids Res., 45, 2017
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1S2N
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1SH7
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1N93
 | | Crystal Structure of the Borna Disease Virus Nucleoprotein | | Descriptor: | p40 nucleoprotein | | Authors: | Rudolph, M.G, Kraus, I, Dickmanns, A, Garten, W, Ficner, R. | | Deposit date: | 2002-11-22 | | Release date: | 2003-10-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Crystal structure of the Borna Disease Virus nucleoprotein
Structure, 11, 2003
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1PP1
 | | Crystal structure of the Borna Disease Virus Nucleoprotein | | Descriptor: | p40 nucleoprotein | | Authors: | Rudolph, M.G, Kraus, I, Dickmanns, A, Garten, W, Ficner, R. | | Deposit date: | 2003-06-16 | | Release date: | 2003-10-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of the Borna Disease Virus nucleoprotein
Structure, 11, 2003
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5LTA
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5LTJ
 | | Crystal structure of the Prp43-ADP-BeF3 complex (in orthorhombic space group) | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Tauchert, M.J, Ficner, R. | | Deposit date: | 2016-09-06 | | Release date: | 2017-01-25 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Structural insights into the mechanism of the DEAH-box RNA helicase Prp43.
Elife, 6, 2017
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5LTK
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6FA9
 | | CRYSTAL STRUCTURE OF THE DEAH-BOX HELICASE PRP2 | | Descriptor: | Putative mRNA splicing factor, SULFATE ION | | Authors: | Schmitt, A, Hamann, F, Neumann, P, Ficner, R. | | Deposit date: | 2017-12-15 | | Release date: | 2018-07-11 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of the spliceosomal DEAH-box ATPase Prp2.
Acta Crystallogr D Struct Biol, 74, 2018
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