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Synthesis and SAR of guanine based analogues for HPPK inhibitors
Descriptor:	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 7-(2-HYDROXYETHYL)-8-MERCAPTOGUANINE
Authors:	Chhabra, S, Peat, T.S, Swarbrick, J.
Deposit date:	2011-12-22
Release date:	2013-01-16
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (1.85 Å)
Cite:	Exploring the Chemical Space Around 8-Mercaptoguanine as a Route to New Inhibitors of the Folate Biosynthesis Enzyme Hppk. Plos One, 8, 2013

Structure and design of a new pterin site inhibitor of S. aureus HPPK
Descriptor:	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 2-amino-8-sulfanyl-1,9-dihydro-6H-purin-6-one
Authors:	Peat, T.S, Chhabra, S, Swarbrick, J.D.
Deposit date:	2011-01-12
Release date:	2012-01-25
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (1.65 Å)
Cite:	Structure of S. aureus HPPK and the discovery of a new substrate site inhibitor Plos One, 7, 2012

Crystal structure of benzophenone synthase from Garcinia mangostana L. pericarps reveals basis for substrate specificity and catalysis
Descriptor:	2,4,6-trihydroxybenzophenone synthase, GLYCEROL, IMIDAZOLE, ...
Authors:	Songsiriritthigul, C, Nualkaew, N, Chen, C.-J.
Deposit date:	2020-06-12
Release date:	2020-12-09
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.301 Å)
Cite:	Crystal structure of benzophenone synthase from Garcinia mangostana L. pericarps reveals basis for substrate specificity and catalysis. Acta Crystallogr.,Sect.F, 76, 2020

STRUCTURE OF E. COLI THREONYL-TRNA SYNTHETASE COMPLEXED WITH ITS COGNATE TRNA
Descriptor:	ADENOSINE MONOPHOSPHATE, THREONINE TRNA, THREONYL-TRNA SYNTHETASE, ...
Authors:	Sankaranarayanan, R, Dock-Bregeon, A.C, Rees, B, Moras, D.
Deposit date:	1999-04-06
Release date:	1999-05-06
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (2.9 Å)
Cite:	The structure of threonyl-tRNA synthetase-tRNA(Thr) complex enlightens its repressor activity and reveals an essential zinc ion in the active site Cell(Cambridge,Mass.), 97, 1999