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7ZHF
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BU of 7zhf by Molmil
GPN-loop GTPase from Sulfolobus acidocaldarius closed state (GppNHp)
Descriptor: CHLORIDE ION, GLYCEROL, GTPase, ...
Authors:Korf, L, Essen, L.-O.
Deposit date:2022-04-06
Release date:2023-10-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Archaeal GPN-loop GTPases involve a lock-switch-rock mechanism for GTP hydrolysis.
Mbio, 14, 2023
7ZHK
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BU of 7zhk by Molmil
GPN-loop GTPase from Sulfolobus acidocaldarius open state (GDP)
Descriptor: GTPase, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Korf, L, Essen, L.-O.
Deposit date:2022-04-06
Release date:2023-10-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Archaeal GPN-loop GTPases involve a lock-switch-rock mechanism for GTP hydrolysis.
Mbio, 14, 2023
4BUO
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BU of 4buo by Molmil
High Resolution Structure of Thermostable Agonist-bound Neurotensin Receptor 1 Mutant without Lysozyme Fusion
Descriptor: GLYCINE, NEUROTENSIN RECEPTOR TYPE 1, NEUROTENSIN/NEUROMEDIN N
Authors:Egloff, P, Hillenbrand, M, Schlinkmann, K.M, Batyuk, A, Mittl, P, Plueckthun, A.
Deposit date:2013-06-21
Release date:2014-01-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli
Proc.Natl.Acad.Sci.USA, 111, 2014
7PNB
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BU of 7pnb by Molmil
Sulfolobus acidocaldarius 0406 filament.
Descriptor: 6-deoxy-6-sulfo-beta-D-glucopyranose-(1-3)-[alpha-D-mannopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sulfolobus acidocaldarius 0406 filament., beta-D-glucopyranose-(1-4)-6-deoxy-6-sulfo-beta-D-glucopyranose-(1-3)-[alpha-D-mannopyranose-(1-4)][alpha-D-mannopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Isupov, M.N, Gaines, M, Daum, B.
Deposit date:2021-09-06
Release date:2022-09-14
Last modified:2023-03-29
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Electron cryo-microscopy reveals the structure of the archaeal thread filament.
Nat Commun, 13, 2022
7U0H
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BU of 7u0h by Molmil
State NE1 nucleolar 60S ribosome biogenesis intermediate - Overall model
Descriptor: 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ...
Authors:Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
Deposit date:2022-02-18
Release date:2022-12-14
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7R7O
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BU of 7r7o by Molmil
Structure of methyltransferase domain of Spb1 boudn to SAM
Descriptor: AdoMet-dependent rRNA methyltransferase SPB1, S-ADENOSYLMETHIONINE
Authors:Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
Deposit date:2021-06-25
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Post-catalytic rRNA binding by the DEAD-box ATPase Spb4 and methyltransferase Spb1 guide the late nucleolar assembly of 60S ribosomes
To Be Published
7R6K
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BU of 7r6k by Molmil
State E2 nucleolar 60S ribosomal intermediate - Model for Noc2/Noc3 region
Descriptor: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
Authors:Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
Deposit date:2021-06-22
Release date:2022-11-09
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7R7C
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BU of 7r7c by Molmil
State E2 nucleolar 60S ribosomal biogenesis intermediate - L1 stalk local model
Descriptor: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
Authors:Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
Deposit date:2021-06-24
Release date:2022-11-09
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7R72
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BU of 7r72 by Molmil
State E1 nucleolar 60S ribosome biogenesis intermediate - Spb4 local model
Descriptor: 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ...
Authors:Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
Deposit date:2021-06-24
Release date:2022-11-09
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7R6Q
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BU of 7r6q by Molmil
State E2 nucleolar 60S ribosome biogenesis intermediate - Foot region model
Descriptor: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ...
Authors:Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
Deposit date:2021-06-23
Release date:2022-11-09
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7R7A
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BU of 7r7a by Molmil
State E1 nucleolar 60S ribosome biogenesis intermediate - Composite model
Descriptor: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
Authors:Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
Deposit date:2021-06-24
Release date:2022-11-09
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7NAD
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BU of 7nad by Molmil
State E2 nucleolar 60S ribosomal biogenesis intermediate - Spb4 local refinement model
Descriptor: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L17-A, ...
Authors:Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
Deposit date:2021-06-21
Release date:2022-11-09
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7NAC
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BU of 7nac by Molmil
State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model
Descriptor: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
Authors:Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
Deposit date:2021-06-21
Release date:2022-11-09
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
7NAF
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BU of 7naf by Molmil
State E2 nucleolar 60S ribosomal biogenesis intermediate - Spb1-MTD local model
Descriptor: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ...
Authors:Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P.
Deposit date:2021-06-21
Release date:2022-11-09
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Nat.Struct.Mol.Biol., 29, 2022
8Q30
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BU of 8q30 by Molmil
Sulfolobus acidocaldarius AAP filament.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-deoxy-6-sulfo-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Isupov, M.N, Gaines, M, Daum, B, McLaren, M.
Deposit date:2023-08-03
Release date:2024-03-06
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:CryoEM reveals the structure of an archaeal pilus involved in twitching motility.
Nat Commun, 15, 2024
8E2M
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BU of 8e2m by Molmil
Bruton's tyrosine kinase (BTK) with compound 13
Descriptor: (5P)-5-[4-methyl-6-(2-methylpropyl)pyridin-3-yl]-4-oxo-N-[(1R,2S)-2-propanamidocyclopentyl]-4,5-dihydro-3H-1-thia-3,5,8-triazaacenaphthylene-2-carboxamide, TRIETHYLENE GLYCOL, Tyrosine-protein kinase BTK
Authors:Alexander, R, Milligan, C.M.
Deposit date:2022-08-15
Release date:2022-11-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.904 Å)
Cite:Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase.
J.Med.Chem., 65, 2022
3K33
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BU of 3k33 by Molmil
Crystal structure of the Phd-Doc complex
Descriptor: ACETATE ION, Death on curing protein, Polypeptide of unknown amino acids and source, ...
Authors:Loris, R, Garcia-Pino, A.
Deposit date:2009-10-01
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Allostery and intrinsic disorder mediate transcription regulation by conditional cooperativity.
Cell(Cambridge,Mass.), 142, 2010
5YDX
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BU of 5ydx by Molmil
NMR structure of YAP1-2 WW1 domain with LATS1 PPxY motif complex
Descriptor: WW domain with PPxY motif
Authors:Fan, J.S, Sivaraman, J.
Deposit date:2017-09-15
Release date:2018-05-02
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Biophysical studies and NMR structure of YAP2 WW domain - LATS1 PPxY motif complexes reveal the basis of their interaction.
Oncotarget, 9, 2018
5YDY
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BU of 5ydy by Molmil
NMR structure of YAP1-2 WW2 domain with LATS1 PPxY motif complex
Descriptor: WW2 domain and PPxY motif complex
Authors:Fan, J.S, Sivaraman, J.
Deposit date:2017-09-15
Release date:2018-05-02
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Biophysical studies and NMR structure of YAP2 WW domain - LATS1 PPxY motif complexes reveal the basis of their interaction.
Oncotarget, 9, 2018
3HS2
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BU of 3hs2 by Molmil
Crystal structure of PHD truncated to residue 57 in an orthorhombic space group
Descriptor: Prevent host death protein, SULFATE ION
Authors:Garcia-Pino, A, Loris, R.
Deposit date:2009-06-10
Release date:2010-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Allostery and intrinsic disorder mediate transcription regulation by conditional cooperativity.
Cell(Cambridge,Mass.), 142, 2010
3HRY
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BU of 3hry by Molmil
Crystal structure of PHD in a trigonal space group and partially disordered
Descriptor: Prevent host death protein
Authors:Garcia-Pino, A, Loris, R.
Deposit date:2009-06-10
Release date:2010-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Allostery and intrinsic disorder mediate transcription regulation by conditional cooperativity.
Cell(Cambridge,Mass.), 142, 2010
3V10
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BU of 3v10 by Molmil
Crystal structure of the collagen binding domain of Erysipelothrix rhusiopathiae surface protein RspB
Descriptor: Rhusiopathiae surface protein B
Authors:Ponnuraj, K, Swarmistha devi, A, Ogawa, Y, Shimoji, Y, Subramainan, B.
Deposit date:2011-12-09
Release date:2012-10-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Collagen adhesin-nanoparticle interaction impairs adhesin's ligand binding mechanism
Biochim.Biophys.Acta, 1820, 2012
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