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7R7O

Structure of methyltransferase domain of Spb1 boudn to SAM

Summary for 7R7O
Entry DOI10.2210/pdb7r7o/pdb
Related7NAC 7NAD 7NAF 7R6K 7R6Q 7R72 7R7A 7R7C
EMDB information24269 24270 24271 24280 24286 24290 24296 24297
DescriptorAdoMet-dependent rRNA methyltransferase SPB1, S-ADENOSYLMETHIONINE (3 entities in total)
Functional Keywordsribosome biogenesis, methyltransferase, nucleolus, transferase
Biological sourceSaccharomyces cerevisiae (Baker's yeast)
Total number of polymer chains2
Total formula weight50777.26
Authors
Cruz, V.E.,Sekulski, K.,Peddada, N.,Erzberger, J.P. (deposition date: 2021-06-25, release date: 2022-06-29, Last modification date: 2023-10-18)
Primary citationCruz, V.E.,Sekulski, K.,Peddada, N.,Sailer, C.,Balasubramanian, S.,Weirich, C.S.,Stengel, F.,Erzberger, J.P.
Post-catalytic rRNA binding by the DEAD-box ATPase Spb4 and methyltransferase Spb1 guide the late nucleolar assembly of 60S ribosomes
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.58 Å)
Structure validation

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