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6SJE
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BU of 6sje by Molmil
Cryo-EM structure of the RecBCD Chi partially-recognised complex
Descriptor: DNA fork substrate, RecBCD enzyme subunit RecB, RecBCD enzyme subunit RecC, ...
Authors:Cheng, K, Wilkinson, M, Wigley, D.B.
Deposit date:2019-08-13
Release date:2020-01-01
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:A conformational switch in response to Chi converts RecBCD from phage destruction to DNA repair.
Nat.Struct.Mol.Biol., 27, 2020
6T2U
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BU of 6t2u by Molmil
Cryo-EM structure of the RecBCD in complex with Chi-minus2 substrate
Descriptor: DNA (Chi-minus2), RecBCD enzyme subunit RecB, RecBCD enzyme subunit RecC, ...
Authors:Cheng, K, Wilkinson, M, Wigley, D.B.
Deposit date:2019-10-09
Release date:2020-01-01
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:A conformational switch in response to Chi converts RecBCD from phage destruction to DNA repair.
Nat.Struct.Mol.Biol., 27, 2020
1PJR
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BU of 1pjr by Molmil
STRUCTURE OF DNA HELICASE
Descriptor: PCRA
Authors:Subramanya, H.S, Bird, L.E, Brannigan, J.A, Wigley, D.B.
Deposit date:1996-10-11
Release date:1997-12-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a DExx box DNA helicase.
Nature, 384, 1996
1OTG
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BU of 1otg by Molmil
5-CARBOXYMETHYL-2-HYDROXYMUCONATE ISOMERASE
Descriptor: 5-CARBOXYMETHYL-2-HYDROXYMUCONATE ISOMERASE, SULFATE ION
Authors:Subramanya, H.S, Roper, D.I, Dauter, Z, Dodson, E.J, Davies, G.J, Wilson, K.S, Wigley, D.B.
Deposit date:1995-11-09
Release date:1996-04-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Enzymatic ketonization of 2-hydroxymuconate: specificity and mechanism investigated by the crystal structures of two isomerases.
Biochemistry, 35, 1996
1QHH
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BU of 1qhh by Molmil
STRUCTURE OF DNA HELICASE WITH ADPNP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, PROTEIN (PCRA (SUBUNIT))
Authors:Soultanas, P, Dillingham, M.S, Velankar, S.S, Wigley, D.B.
Deposit date:1999-05-14
Release date:1999-07-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:DNA binding mediates conformational changes and metal ion coordination in the active site of PcrA helicase.
J.Mol.Biol., 290, 1999
1QHG
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BU of 1qhg by Molmil
STRUCTURE OF DNA HELICASE MUTANT WITH ADPNP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-DEPENDENT HELICASE PCRA, MAGNESIUM ION
Authors:Soultanas, P, Dillingham, M.S, Velankar, S.S, Wigley, D.B.
Deposit date:1999-05-14
Release date:1999-07-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:DNA binding mediates conformational changes and metal ion coordination in the active site of PcrA helicase.
J.Mol.Biol., 290, 1999
1CKO
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BU of 1cko by Molmil
STRUCTURE OF MRNA CAPPING ENZYME IN COMPLEX WITH THE CAP ANALOG GPPPG
Descriptor: DIGUANOSINE-5'-TRIPHOSPHATE, MRNA CAPPING ENZYME, ZINC ION
Authors:Hakansson, K, Wigley, D.B.
Deposit date:1997-09-06
Release date:1998-01-28
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of a complex between a cap analogue and mRNA guanylyl transferase demonstrates the structural chemistry of RNA capping.
Proc.Natl.Acad.Sci.USA, 95, 1998
1H2I
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BU of 1h2i by Molmil
Human Rad52 protein, N-terminal domain
Descriptor: DNA REPAIR PROTEIN RAD52 HOMOLOG
Authors:Singleton, M.R, Wentzell, L.M, Liu, Y, West, S.C, Wigley, D.B.
Deposit date:2002-08-09
Release date:2002-10-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the Single-Strand Annealing Domain of Human Rad52 Protein
Proc.Natl.Acad.Sci.USA, 99, 2002
1GM5
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BU of 1gm5 by Molmil
Structure of RecG bound to three-way DNA junction
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-(*CP*AP*GP*CP*TP*CP*CP*AP*TP*GP*AP*TP* CP*AP*TP*TP*GP*GP*CP*A)-3'), DNA (5'-(*GP*AP*GP*CP*AP*CP*TP*GP*C)-3'), ...
Authors:Singleton, M.R, Scaife, S, Wigley, D.B.
Deposit date:2001-09-11
Release date:2001-10-03
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Structural Analysis of DNA Replication Fork Reversal by Recg
Cell(Cambridge,Mass.), 107, 2001
1A0P
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BU of 1a0p by Molmil
SITE-SPECIFIC RECOMBINASE, XERD
Descriptor: SITE-SPECIFIC RECOMBINASE XERD
Authors:Subramanya, H.S, Arciszewska, L.K, Baker, R.A, Bird, L.E, Sherratt, D.J, Wigley, D.B.
Deposit date:1997-12-05
Release date:1998-03-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the site-specific recombinase, XerD.
EMBO J., 16, 1997
1A0I
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BU of 1a0i by Molmil
ATP-DEPENDENT DNA LIGASE FROM BACTERIOPHAGE T7 COMPLEX WITH ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA LIGASE
Authors:Subramanya, H.S, Doherty, A.J, Ashford, S.R, Wigley, D.B.
Deposit date:1997-12-01
Release date:1998-03-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of an ATP-dependent DNA ligase from bacteriophage T7.
Cell(Cambridge,Mass.), 85, 1996
1B04
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BU of 1b04 by Molmil
STRUCTURE OF THE ADENYLATION DOMAIN OF AN NAD+ DEPENDENT LIGASE
Descriptor: PROTEIN (DNA LIGASE)
Authors:Singleton, M.R, Hakansson, K, Timson, D.J, Wigley, D.B.
Deposit date:1998-11-16
Release date:1999-11-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the adenylation domain of an NAD+-dependent DNA ligase.
Structure Fold.Des., 7, 1999
5OAF
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BU of 5oaf by Molmil
Human Rvb1/Rvb2 heterohexamer in INO80 complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
Authors:Aramayo, R.J, Bythell-Douglas, R, Ayala, R, Willhoft, O, Wigley, D, Zhang, X.
Deposit date:2017-06-21
Release date:2017-12-13
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Cryo-EM structures of the human INO80 chromatin-remodeling complex.
Nat. Struct. Mol. Biol., 25, 2018
3U44
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BU of 3u44 by Molmil
Crystal structure of AddAB-DNA complex
Descriptor: ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease subunit A, DNA (36-MER), ...
Authors:Saikrishnan, K, Krajewski, W, Wigley, D.
Deposit date:2011-10-07
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.201 Å)
Cite:Insights into Chi recognition from the structure of an AddAB-type helicase-nuclease complex.
Embo J., 31, 2012
3U4Q
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BU of 3u4q by Molmil
Structure of AddAB-DNA complex at 2.8 angstroms
Descriptor: 1,2-ETHANEDIOL, ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease subunit A, ...
Authors:Saikrishnan, K, Krajewski, W, Wigley, D.
Deposit date:2011-10-10
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Insights into Chi recognition from the structure of an AddAB-type helicase-nuclease complex.
Embo J., 31, 2012
5DMA
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BU of 5dma by Molmil
Crystal structure of C-terminal tudor domain in PcrA/UvrD helicase
Descriptor: ATP-dependent DNA helicase PcrA
Authors:Lin, C.L, Dillingham, M, Wigley, D.
Deposit date:2015-09-08
Release date:2016-09-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:The structure and function of an RNA polymerase interaction domain in the PcrA/UvrD helicase.
Nucleic Acids Res., 45, 2017
6FWS
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BU of 6fws by Molmil
Structure of DinG in complex with ssDNA and ADPBeF
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DinG, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Cheng, K, Wigley, D.
Deposit date:2018-03-07
Release date:2018-12-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:DNA translocation mechanism of an XPD family helicase.
Elife, 7, 2018
4CEJ
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BU of 4cej by Molmil
Crystal structure of AddAB-DNA-ADPNP complex at 3 Angstrom resolution
Descriptor: ATP-DEPENDENT HELICASE/DEOXYRIBONUCLEASE SUBUNIT B, ATP-DEPENDENT HELICASE/NUCLEASE SUBUNIT A, DNA, ...
Authors:Krajewski, W.W, Wilkinson, M, Fu, X, Cronin, N.B, Wigley, D.
Deposit date:2013-11-11
Release date:2014-03-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis for Translocation by Addab Helicase-Nuclease and its Arrest at Chi Sites.
Nature, 508, 2014
4CEH
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BU of 4ceh by Molmil
Crystal structure of AddAB with a forked DNA substrate
Descriptor: ATP-DEPENDENT HELICASE/DEOXYRIBONUCLEASE SUBUNIT B, ATP-DEPENDENT HELICASE/NUCLEASE SUBUNIT A, DNA, ...
Authors:Krajewski, W.W, Wilkinson, M, Fu, X, Cronin, N.B, Wigley, D.
Deposit date:2013-11-11
Release date:2014-03-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Structural Basis for Translocation by Addab Helicase-Nuclease and its Arrest at Chi Sites.
Nature, 508, 2014
4CEI
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BU of 4cei by Molmil
Crystal structure of ADPNP-bound AddAB with a forked DNA substrate
Descriptor: ATP-DEPENDENT HELICASE/DEOXYRIBONUCLEASE SUBUNIT B, ATP-DEPENDENT HELICASE/NUCLEASE SUBUNIT A, DNA, ...
Authors:Krajewski, W.W, Wilkinson, M, Fu, X, Cronin, N.B, Wigley, D.
Deposit date:2013-11-11
Release date:2014-03-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Translocation by Addab Helicase-Nuclease and its Arrest at Chi Sites.
Nature, 508, 2014
1P7F
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BU of 1p7f by Molmil
GB3 solution structure obtained by refinement of X-ray structure with dipolar couplings
Descriptor: Immunoglobulin G binding protein G
Authors:Ulmer, T.S, Ramirez, B.E, Delaglio, F, Bax, A.
Deposit date:2003-05-01
Release date:2003-08-05
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Evaluation of backbone proton positions and dynamics in a small protein by liquid crystal NMR spectroscopy.
J.Am.Chem.Soc., 125, 2003
1AJ6
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BU of 1aj6 by Molmil
NOVOBIOCIN-RESISTANT MUTANT (R136H) OF THE N-TERMINAL 24 KDA FRAGMENT OF DNA GYRASE B COMPLEXED WITH NOVOBIOCIN AT 2.3 ANGSTROMS RESOLUTION
Descriptor: GYRASE, NOVOBIOCIN
Authors:Weston, S.A, Tunnicliffe, A, Pauptit, R.A.
Deposit date:1997-05-15
Release date:1998-05-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The entropic penalty of ordered water accounts for weaker binding of the antibiotic novobiocin to a resistant mutant of DNA gyrase: a thermodynamic and crystallographic study.
Biochemistry, 36, 1997
1P7E
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BU of 1p7e by Molmil
GB3 solution structure obtained by refinement of X-ray structure with dipolar couplings
Descriptor: Immunoglobulin G binding protein G
Authors:Ulmer, T.S, Ramirez, B.E, Delaglio, F, Bax, A.
Deposit date:2003-05-01
Release date:2003-08-05
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Evaluation of backbone proton positions and dynamics in a small protein by liquid crystal NMR spectroscopy.
J.Am.Chem.Soc., 125, 2003
1TAE
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BU of 1tae by Molmil
Structural rearrangement accompanying NAD+ synthesis within a bacterial DNA ligase crystal
Descriptor: DNA ligase, NAD-dependent, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Gajiwala, K.S, Pinko, C.
Deposit date:2004-05-19
Release date:2004-11-23
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural rearrangement accompanying NAD+ synthesis within a bacterial DNA ligase crystal.
STRUCTURE, 12, 2004
1TA8
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BU of 1ta8 by Molmil
Structural rearrangement accompanying NAD+ synthesis within a bacterial DNA ligase crystal
Descriptor: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase, NAD-dependent, ...
Authors:Gajiwala, K.S, Pinko, C.
Deposit date:2004-05-19
Release date:2004-11-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural rearrangement accompanying NAD+ synthesis within a bacterial DNA ligase crystal.
STRUCTURE, 12, 2004
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