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8HNT
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BU of 8hnt by Molmil
Crystal structure of anti-CRISPR protein AcrIIC4 bound to HpaCas9-sgRNA surveillance complex
Descriptor: CRISPR-associated endonuclease Cas9, anti-CRISPR protein AcrIIC4, sgRNA
Authors:Sun, W, Cheng, Z, Wang, Y.
Deposit date:2022-12-08
Release date:2023-07-19
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:AcrIIC4 inhibits type II-C Cas9 by preventing R-loop formation.
Proc.Natl.Acad.Sci.USA, 120, 2023
5WTJ
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BU of 5wtj by Molmil
Crystal structure of an endonuclease
Descriptor: CRISPR-associated endoribonuclease C2c2
Authors:Liu, L, Wang, Y.
Deposit date:2016-12-13
Release date:2017-02-08
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (3.503 Å)
Cite:Two Distant Catalytic Sites Are Responsible for C2c2 RNase Activities
Cell, 168, 2017
8JFU
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BU of 8jfu by Molmil
AcrIIA15 in complex with palindromic DNA substrate
Descriptor: AcrIIA15, DNA (5'-D(*AP*TP*TP*AP*TP*GP*AP*CP*AP*AP*AP*TP*GP*TP*CP*AP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*TP*GP*AP*CP*AP*TP*TP*TP*GP*TP*CP*AP*TP*AP*A)-3')
Authors:Deng, X, Wang, Y.
Deposit date:2023-05-18
Release date:2024-02-28
Last modified:2024-09-11
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:An anti-CRISPR that represses its own transcription while blocking Cas9-target DNA binding.
Nat Commun, 15, 2024
8JFO
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BU of 8jfo by Molmil
Crystal structure of anti-CRISPR protein AcrIIA15
Descriptor: AcrIIA15
Authors:Deng, X, Wang, Y.
Deposit date:2023-05-18
Release date:2024-02-28
Last modified:2024-09-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:An anti-CRISPR that represses its own transcription while blocking Cas9-target DNA binding.
Nat Commun, 15, 2024
8JFT
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BU of 8jft by Molmil
Cryo-EM structure of SaCas9-AcrIIA15 CTD-sgRNA complex
Descriptor: AcrIIA15, CRISPR-associated endonuclease Cas9, sgRNA of SaCas9
Authors:Deng, X, Wang, Y.
Deposit date:2023-05-18
Release date:2024-02-28
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:An anti-CRISPR that represses its own transcription while blocking Cas9-target DNA binding.
Nat Commun, 15, 2024
8JFR
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BU of 8jfr by Molmil
N-terminal domain of AcrIIA15 in complex with palindromic DNA substrate
Descriptor: AcrIIA15, DNA (5'-D(*AP*TP*TP*AP*TP*GP*AP*CP*AP*AP*AP*TP*GP*TP*CP*AP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*TP*GP*AP*CP*AP*TP*TP*TP*GP*TP*CP*AP*TP*AP*A)-3')
Authors:Deng, X, Wang, Y.
Deposit date:2023-05-18
Release date:2024-02-28
Last modified:2024-09-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:An anti-CRISPR that represses its own transcription while blocking Cas9-target DNA binding.
Nat Commun, 15, 2024
8JG9
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BU of 8jg9 by Molmil
Cryo-EM structure of the SaCas9-sgRNA-AcrIIA15-promoter DNA dimer
Descriptor: AcrIIA15, CRISPR-associated endonuclease Cas9, DNA (25-MER), ...
Authors:Deng, X, Wang, Y.
Deposit date:2023-05-20
Release date:2024-02-28
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.82 Å)
Cite:An anti-CRISPR that represses its own transcription while blocking Cas9-target DNA binding.
Nat Commun, 15, 2024
4FNF
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BU of 4fnf by Molmil
LT-IIB-B5 S74D mutant
Descriptor: ACETATE ION, Heat-labile enterotoxin IIB, B chain
Authors:Cody, V.
Deposit date:2012-06-19
Release date:2012-11-21
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure-activity correlations of variant forms of the B pentamer of Escherichia coli type II heat-labile enterotoxin LT-IIb with Toll-like receptor 2 binding.
Acta Crystallogr.,Sect.D, 68, 2012
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PDB entries from 2024-11-13

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