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4D3C
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BU of 4d3c by Molmil
Crystal structure of the NK1 domain of HGF in complex with anti-HGF monoclonal antibody SFN68.
Descriptor: HEPATOCYTE GROWTH FACTOR, SFN68 FAB
Authors:Kang, Y.J, Kim, K.L, Cho, H.S, Chung, J.H.
Deposit date:2014-10-21
Release date:2016-01-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist.
to be published
2JGU
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BU of 2jgu by Molmil
crystal structure of DNA-directed DNA polymerase
Descriptor: DNA POLYMERASE, MANGANESE (II) ION
Authors:Kim, D.U, Cho, H.S.
Deposit date:2007-02-15
Release date:2008-04-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Pfu, the High Fidelity DNA Polymerase from Pyrococcus Furiosus.
Int.J.Biol.Macromol., 42, 2008
1L7P
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BU of 1l7p by Molmil
SUBSTRATE BOUND PHOSPHOSERINE PHOSPHATASE COMPLEX STRUCTURE
Descriptor: PHOSPHATE ION, PHOSPHOSERINE, PHOSPHOSERINE PHOSPHATASE
Authors:Wang, W, Cho, H.S, Kim, R, Jancarik, J, Yokota, H, Nguyen, H.H, Grigoriev, I.V, Wemmer, D.E, Kim, S.H, Berkeley Structural Genomics Center (BSGC)
Deposit date:2002-03-16
Release date:2002-06-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic "snapshots" of intermediate states.
J.Mol.Biol., 319, 2002
1L7N
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BU of 1l7n by Molmil
TRANSITION STATE ANALOGUE OF PHOSPHOSERINE PHOSPHATASE (ALUMINUM FLUORIDE COMPLEX)
Descriptor: ALUMINUM FLUORIDE, MAGNESIUM ION, PHOSPHOSERINE PHOSPHATASE, ...
Authors:Wang, W, Cho, H.S, Kim, R, Jancarik, J, Yokota, H, Nguyen, H.H, Grigoriev, I.V, Wemmer, D.E, Kim, S.H, Berkeley Structural Genomics Center (BSGC)
Deposit date:2002-03-16
Release date:2002-06-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic "snapshots" of intermediate states.
J.Mol.Biol., 319, 2002
1L7M
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BU of 1l7m by Molmil
HIGH RESOLUTION LIGANDED STRUCTURE OF PHOSPHOSERINE PHOSPHATASE (PI COMPLEX)
Descriptor: MAGNESIUM ION, PHOSPHATE ION, Phosphoserine Phosphatase
Authors:Wang, W, Cho, H.S, Kim, R, Jancarik, J, Yokota, H, Nguyen, H.H, Grigoriev, I.V, Wemmer, D.E, Kim, S.H, Berkeley Structural Genomics Center (BSGC)
Deposit date:2002-03-15
Release date:2002-04-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic "snapshots" of intermediate states.
J.Mol.Biol., 319, 2002
1L7O
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BU of 1l7o by Molmil
CRYSTAL STRUCTURE OF PHOSPHOSERINE PHOSPHATASE IN APO FORM
Descriptor: ACETIC ACID, PHOSPHOSERINE PHOSPHATASE, ZINC ION
Authors:Wang, W, Cho, H.S, Kim, R, Jancarik, J, Yokota, H, Nguyen, H.H, Grigoriev, I.V, Wemmer, D.E, Kim, S.H, Berkeley Structural Genomics Center (BSGC)
Deposit date:2002-03-16
Release date:2002-06-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic "snapshots" of intermediate states.
J.Mol.Biol., 319, 2002
1PUX
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BU of 1pux by Molmil
NMR Solution Structure of BeF3-Activated Spo0F, 20 conformers
Descriptor: Sporulation initiation phosphotransferase F
Authors:Gardino, A.K, Volkman, B.F, Cho, H.S, Lee, S.Y, Wemmer, D.E, Kern, D.
Deposit date:2003-06-25
Release date:2003-08-19
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The NMR solution structure of BeF(3)(-)-activated Spo0F reveals the conformational switch in a phosphorelay system.
J.Mol.Biol., 331, 2003
5FJG
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BU of 5fjg by Molmil
The crystal structure of light-driven chloride pump ClR in pH 4.5.
Descriptor: ANHYDRORETINOL, CHLORIDE ION, CHLORIDE PUMPING RHODOPSIN, ...
Authors:Kim, K.L, Kwon, S.K, Jun, S.H, Cha, J.S, Kim, H.Y, Kim, J.H, Cho, H.S.
Deposit date:2015-10-07
Release date:2016-11-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of Light-Driven Chloride Pump Clr in Ph 4.5.
To be Published
5A2P
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BU of 5a2p by Molmil
THE COMPLEX STRUCTURE OF PDZ DOMAINS IN SYNTENIN-1 WITH 4L PEPTIDE
Descriptor: SYNDECAN-4, SYNTENIN-1
Authors:Yoo, J.H, Yun, J.H, Cho, H.S, Lee, W.
Deposit date:2015-05-21
Release date:2016-06-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.496 Å)
Cite:Titl the Complex Structure of Pdz Domains in Syntenin-1 with 4L Peptide
To be Published
2XHS
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BU of 2xhs by Molmil
Crystal structure of the ligand binding domain of Fushi tarazu factor 1 of Drosophila melanogaster.
Descriptor: NUCLEAR HORMONE RECEPTOR FTZ-F1, SEGMENTATION PROTEIN FUSHI TARAZU
Authors:Yoo, J.H, Cho, H.S.
Deposit date:2010-06-21
Release date:2011-07-20
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Fushi Tarazu Factor 1 Ligand Binding Domain/Fushi Tarazu Peptide Complex Identifies New Class of Nuclear Receptors.
J.Biol.Chem., 286, 2011
2X29
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BU of 2x29 by Molmil
Crystal structure of human4-1BB ligand ectodomain
Descriptor: TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 9
Authors:Won, E.Y, Cho, H.S.
Deposit date:2010-01-12
Release date:2010-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Structure of the Trimer of Human 4-1Bb Ligand is Unique Among Members of the Tumor Necrosis Factor Superfamily.
J.Biol.Chem., 285, 2010
8CHO
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BU of 8cho by Molmil
CRYSTAL STRUCTURE OF DELTA5-3-KETOSTEROID ISOMERASE FROM PSEUDOMONAS TESTOSTERONI
Descriptor: O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, STEROID DELTA-ISOMERASE
Authors:Cho, H.-S, Oh, B.-H.
Deposit date:1998-01-06
Release date:1999-02-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure and enzyme mechanism of Delta 5-3-ketosteroid isomerase from Pseudomonas testosteroni.
Biochemistry, 37, 1998
1M6B
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BU of 1m6b by Molmil
Structure of the HER3 (ERBB3) Extracellular Domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor protein-tyrosine kinase erbB-3, ...
Authors:Leahy, D.J, Cho, H.-S.
Deposit date:2002-07-15
Release date:2002-08-02
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the extracellular region of HER3 reveals an interdomain tether.
Science, 297, 2002
4YNE
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BU of 4yne by Molmil
(R)-2-Phenylpyrrolidine Substitute Imidazopyridazines: a New Class of Potent and Selective Pan-TRK Inhibitors
Descriptor: 6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]-3-(pyridin-2-yl)imidazo[1,2-b]pyridazine, GLYCEROL, High affinity nerve growth factor receptor, ...
Authors:Kreusch, A, Rucker, P, Molteni, V, Loren, J.
Deposit date:2015-03-09
Release date:2015-06-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.0229 Å)
Cite:(R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors.
Acs Med.Chem.Lett., 6, 2015
4YPS
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BU of 4yps by Molmil
(R)-2-Phenylpyrrolidine Substitute Imidazopyridazines: a New Class of Potent and Selective Pan-TRK Inhibitors
Descriptor: 4-{6-[(3R)-3-(3-fluorophenyl)morpholin-4-yl]imidazo[1,2-b]pyridazin-3-yl}benzonitrile, High affinity nerve growth factor receptor, SULFATE ION
Authors:Kreusch, A, Rucker, P, Molteni, V, Loren, J.
Deposit date:2015-03-13
Release date:2015-06-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1012 Å)
Cite:(R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors.
Acs Med.Chem.Lett., 6, 2015
4YMJ
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BU of 4ymj by Molmil
(R)-2-Phenylpyrrolidine Substitute Imidazopyridazines: a New Class of Potent and Selective Pan-TRK Inhibitors
Descriptor: 4-[6-(benzylamino)imidazo[1,2-b]pyridazin-3-yl]benzonitrile, CHLORIDE ION, GLYCEROL, ...
Authors:Kreusch, A, Rucker, P, Molteni, V, Loren, J.
Deposit date:2015-03-06
Release date:2015-06-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:(R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors.
Acs Med.Chem.Lett., 6, 2015
8UK7
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BU of 8uk7 by Molmil
Periplasmic domain of Escherichia coli CpxA
Descriptor: Sensor histidine kinase CpxA
Authors:Glover, M.J.N, Murray, C.R.A, Edwards, R.A, Thede, G.L.
Deposit date:2023-10-12
Release date:2023-10-25
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The sensor of the bacterial histidine kinase CpxA is a novel dimer of extracytoplasmic Per-ARNT-Sim domains.
J.Biol.Chem., 300, 2024
6XJF
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BU of 6xjf by Molmil
X-ray crystal structure of Pyrococcus furiosus general transcription factor TFE-alpha (SeMet labeled protein)
Descriptor: Transcription factor E
Authors:Murakami, K.S, Jun, S.H.
Deposit date:2020-06-23
Release date:2020-07-08
Last modified:2021-01-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase.
Nat Commun, 11, 2020
4UIP
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BU of 4uip by Molmil
The complex structure of extracellular domain of EGFR with Repebody (rAC1).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EPIDERMAL GROWTH FACTOR RECEPTOR, ...
Authors:Kang, Y.J, Cha, Y.J, Cho, H.S, Lee, J.J, Kim, H.S.
Deposit date:2015-03-31
Release date:2015-11-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Enzymatic Prenylation and Oxime Ligation for the Synthesis of Stable and Homogeneous Protein-Drug Conjugates for Targeted Therapy.
Angew.Chem.Int.Ed.Engl., 54, 2015
4ML7
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BU of 4ml7 by Molmil
Crystal structure of Brucella abortus PliC in complex with human lysozyme
Descriptor: Humanlysozyme, Lysozyme C
Authors:Ha, N.C, Um, S.H, Kim, J.S.
Deposit date:2013-09-06
Release date:2014-07-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for the Inhibition of Human Lysozyme by PliC from Brucella abortus
Biochemistry, 52, 2013
4MIR
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BU of 4mir by Molmil
The structure of Brucella abortus PliC in the hexagonal crystal form
Descriptor: Putative uncharacterized protein
Authors:Ha, N.C, Um, S.H, Kim, J.S.
Deposit date:2013-09-02
Release date:2014-07-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the inhibition of human lysozyme by PliC from Brucella abortus
Biochemistry, 52, 2013
4MIS
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BU of 4mis by Molmil
The structure of Brucella abortus PliC in the orthorombic crystal form
Descriptor: Putative uncharacterized protein
Authors:Ha, N.C, Um, S.H, Kim, J.S.
Deposit date:2013-09-02
Release date:2014-07-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the inhibition of human lysozyme by PliC from Brucella abortus
Biochemistry, 52, 2013
1W02
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BU of 1w02 by Molmil
Crystal structure of mutant enzyme Y16F/D103L of ketosteroid isomerase from Pseudomonas putida biotype B
Descriptor: STEROID DELTA-ISOMERASE
Authors:Jang, D.S, Choi, K.Y.
Deposit date:2004-05-30
Release date:2004-07-08
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Double-Mutant Cycle Analysis of a Hydrogen Bond Network in Ketosteroid Isomerase from Pseudomonas Putida Biotype B.
Biochem.J., 382, 2004
1W01
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BU of 1w01 by Molmil
Crystal structure of mutant enzyme Y57F/D103L of ketosteroid isomerase from Pseudomonas putida biotype B
Descriptor: STEROID DELTA-ISOMERASE
Authors:Jang, D.S, Choi, K.Y.
Deposit date:2004-05-30
Release date:2004-07-08
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Double-Mutant Cycle Analysis of a Hydrogen Bond Network in Ketosteroid Isomerase from Pseudomonas Putida Biotype B.
Biochem.J., 382, 2004
4TSV
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BU of 4tsv by Molmil
HIGH RESOLUTION CRYSTAL STRUCTURE OF A HUMAN TNF-ALPHA MUTANT
Descriptor: TUMOR NECROSIS FACTOR-ALPHA
Authors:Cha, S.-S, Kim, J.-S, Cho, H.-S, Oh, B.-H.
Deposit date:1997-10-29
Release date:1998-12-30
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High resolution crystal structure of a human tumor necrosis factor-alpha mutant with low systemic toxicity.
J.Biol.Chem., 273, 1998

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