6WSA
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6WSB
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3F9Q
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8ENU
| Structure of the C3bB proconvertase in complex with lufaxin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3 beta chain, Complement C3b alpha' chain, ... | Authors: | Andersen, J.F, Lei, H. | Deposit date: | 2022-09-30 | Release date: | 2023-08-09 | Last modified: | 2024-10-23 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism. Blood, 141, 2023
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8EO2
| Lufaxin a bifunctional inhibitor of complement and coagulation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, ... | Authors: | Andersen, J.F, Strayer, E.C. | Deposit date: | 2022-10-01 | Release date: | 2023-08-09 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism. Blood, 141, 2023
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8EOK
| Structure of the C3bB proconvertase in complex with lufaxin and factor Xa | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Activated factor Xa heavy chain, Complement C3 beta chain, ... | Authors: | Andersen, J.F, Lei, H. | Deposit date: | 2022-10-03 | Release date: | 2023-08-30 | Last modified: | 2024-10-30 | Method: | ELECTRON MICROSCOPY (3.53 Å) | Cite: | A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism. Blood, 141, 2023
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6B1Z
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6BRL
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5TGD
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