6IVX
 
 | | Discovery of the Second Generation ROR gamma Inhibitors Composed of an Azole Scaffold. | | Descriptor: | (4S)-4-[4'-cyclopropyl-5-(2,2-dimethylpropyl)[3,5'-bi-1,2-oxazol]-3'-yl]-6-[(2,4-dichlorophenyl)amino]-6-oxohexanoic acid, Nuclear receptor ROR-gamma, Nuclear receptor corepressor 2 | | Authors: | Noguchi, M, Nomura, A, Doi, S, Adachi, T. | | Deposit date: | 2018-12-04 | | Release date: | 2019-03-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Discovery of Second Generation ROR gamma Inhibitors Composed of an Azole Scaffold.
J. Med. Chem., 62, 2019
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6KD5
 | | Crystal structure of the extracellular domain of MSPL/TMPRSS13 in complex with dec-RVKR-cmk inhibitor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR, ... | | Authors: | Ohno, A, Maita, N, Okumura, Y, Nikawa, T. | | Deposit date: | 2019-06-30 | | Release date: | 2020-06-24 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza.
Life Sci Alliance, 4, 2021
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1CYC
 | | THE CRYSTAL STRUCTURE OF BONITO (KATSUO) FERROCYTOCHROME C AT 2.3 ANGSTROMS RESOLUTION. II. STRUCTURE AND FUNCTION | | Descriptor: | FERROCYTOCHROME C, HEME C | | Authors: | Tanaka, N, Yamane, T, Tsukihara, T, Ashida, T, Kakudo, M. | | Deposit date: | 1976-08-01 | | Release date: | 1976-10-06 | | Last modified: | 2021-03-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The crystal structure of bonito (katsuo) ferrocytochrome c at 2.3 A resolution. II. Structure and function.
J.Biochem.(Tokyo), 77, 1975
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5H5L
 | | Structure of prostaglandin synthase D of Nilaparvata lugens | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLUTATHIONE, ... | | Authors: | Yamamoto, K, Higashiura, A, Suzuki, S, Nakagawa, A. | | Deposit date: | 2016-11-07 | | Release date: | 2017-09-20 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.999 Å) | | Cite: | Molecular structure of a prostaglandin D synthase requiring glutathione from the brown planthopper, Nilaparvata lugens
Biochem. Biophys. Res. Commun., 492, 2017
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6KAW
 | | Crystal structure of CghA | | Descriptor: | CghA | | Authors: | Hara, K, Hashimoto, H, Yokoyama, M, Sato, M, Watanabe, K. | | Deposit date: | 2019-06-24 | | Release date: | 2020-06-24 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Catalytic mechanism and endo-to-exo selectivity reversion of an octalin-forming natural Diels-Alderase
Nat Catal, 2021
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6KBC
 | | Crystal structure of CghA with Sch210972 | | Descriptor: | (2S)-3-[(2S,4E)-4-[[(1R,2S,4aR,6S,8R,8aS)-2-[(E)-but-2-en-2-yl]-6,8-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]-oxidanyl-methylidene]-3,5-bis(oxidanylidene)pyrrolidin-2-yl]-2-methyl-2-oxidanyl-propanoic acid, CghA | | Authors: | Hara, K, Hashimoto, H, Maeda, N, Sato, M, Watanabe, K. | | Deposit date: | 2019-06-24 | | Release date: | 2020-06-24 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Catalytic mechanism and endo-to-exo selectivity reversion of an octalin-forming natural Diels-Alderase
Nat Catal, 2021
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2KTD
 | | Solution structure of mouse lipocalin-type prostaglandin D synthase / substrate analog (U-46619) complex | | Descriptor: | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, Prostaglandin-H2 D-isomerase | | Authors: | Shimamoto, S, Maruo, H, Yoshida, T, Kato, N, Ohkubo, T. | | Deposit date: | 2010-01-27 | | Release date: | 2011-02-02 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of Lipocalin-type Prostaglandin D synthase / Substrate analog complex reveals Open-Closed Conformational Change required for Substrate Recognition
To be Published
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3VPT
 | | Crystal structure of Bombyx mori sigma-class glutathione transferase in apo form | | Descriptor: | DI(HYDROXYETHYL)ETHER, Glutathione S-transferase sigma, S-1,2-PROPANEDIOL, ... | | Authors: | Yamamoto, K, Higashiura, A, Suzuki, M, Nakagawa, A. | | Deposit date: | 2012-03-13 | | Release date: | 2013-03-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of a Bombyx mori sigma-class glutathione transferase exhibiting prostaglandin E synthase activity
Biochim.Biophys.Acta, 1830, 2013
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3VPQ
 | | Crystal structure of Bombyx mori sigma-class glutathione transferase in complex with glutathione | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLUTATHIONE, Glutathione S-transferase sigma, ... | | Authors: | Yamamoto, K, Higashiura, A, Nakagawa, A, Suzuki, M. | | Deposit date: | 2012-03-08 | | Release date: | 2013-03-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.702 Å) | | Cite: | Crystal structure of a Bombyx mori sigma-class glutathione transferase exhibiting prostaglandin E synthase activity
Biochim.Biophys.Acta, 1830, 2013
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2TAA
 | | STRUCTURE AND POSSIBLE CATALYTIC RESIDUES OF TAKA-AMYLASE A | | Descriptor: | CALCIUM ION, TAKA-AMYLASE A | | Authors: | Kusunoki, M, Matsuura, Y, Tanaka, N, Kakudo, M. | | Deposit date: | 1982-10-18 | | Release date: | 1982-10-21 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure and possible catalytic residues of Taka-amylase A
J.Biochem.(Tokyo), 95, 1984
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3VI7
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3VI5
 | | Human hematopoietic prostaglandin D synthase inhibitor complex structures | | Descriptor: | 1-amino-9,10-dioxo-4-[(4-sulfamoylphenyl)amino]-9,10-dihydroanthracene-2-sulfonic acid, CALCIUM ION, GLUTATHIONE, ... | | Authors: | Kado, Y, Inoue, T. | | Deposit date: | 2011-09-21 | | Release date: | 2012-04-18 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Human hematopoietic prostaglandin D synthase inhibitor complex structures
J.Biochem., 151, 2012
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