3F51
| Crystal Structure of the clp gene regulator ClgR from Corynebacterium glutamicum | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, Clp gene regulator (ClgR) | Authors: | Russo, S, Schweitzer, J.E, Polen, T, Bott, M, Pohl, E. | Deposit date: | 2008-11-03 | Release date: | 2008-11-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structure of the caseinolytic protease gene regulator, a transcriptional activator in actinomycetes J.Biol.Chem., 284, 2009
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1E3O
| Crystal structure of Oct-1 POU dimer bound to MORE | Descriptor: | 5'-D(*AP*TP*GP*CP*AP*TP*GP*AP*GP*GP*A)-3', 5'-D(*TP*CP*CP*TP*CP*AP*TP*GP*CP*AP*T)-3', OCTAMER-BINDING TRANSCRIPTION FACTOR 1 | Authors: | Remenyi, A, Tomilin, A, Pohl, E, Schoeler, H, Wilmanns, M. | Deposit date: | 2000-06-20 | Release date: | 2001-11-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Differential Dimer Activities of the Transcription Factor Oct-1 by DNA-Induced Interface Swapping Mol.Cell, 8, 2001
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7OB6
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7OB7
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4R8H
| The role of protein-ligand contacts in allosteric regulation of the Escherichia coli Catabolite Activator Protein | Descriptor: | 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL, GLYCEROL, cAMP-activated global transcriptional regulator CRP | Authors: | Townsend, P.D, Pohl, E, McLeish, T.C.B, Rodgers, T.L, Glover, L.C, Korhonen, H.J, Wilson, M.R, Hodgson, D.R.W, Cann, M.J. | Deposit date: | 2014-09-02 | Release date: | 2015-07-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | The Role of Protein-Ligand Contacts in Allosteric Regulation of the Escherichia coli Catabolite Activator Protein. J.Biol.Chem., 290, 2015
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2DTR
| STRUCTURE OF DIPHTHERIA TOXIN REPRESSOR | Descriptor: | COBALT (II) ION, DIPHTHERIA TOXIN REPRESSOR, SULFATE ION | Authors: | Qiu, X, Pohl, E, Hol, W.G. | Deposit date: | 1996-07-26 | Release date: | 1997-08-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High-resolution structure of the diphtheria toxin repressor complexed with cobalt and manganese reveals an SH3-like third domain and suggests a possible role of phosphate as co-corepressor. Biochemistry, 35, 1996
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2R91
| Crystal Structure of KD(P)GA from T.tenax | Descriptor: | 2-Keto-3-deoxy-(6-phospho-)gluconate aldolase, SULFATE ION | Authors: | Pauluhn, A, Pohl, E, Lorentzen, E, Siebers, B, Ahmed, H, Buchinger, S, Schomburg, D. | Deposit date: | 2007-09-12 | Release date: | 2008-03-18 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure and stereochemical studies of KD(P)G aldolase from Thermoproteus tenax. Proteins, 72, 2008
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6HKR
| Human Cellular Retinoic Acid Binding Protein II (CRABPII) with bound synthetic retinoid DC271. | Descriptor: | 1,2-ETHANEDIOL, 4-[2-(4,4-dimethyl-1-propan-2-yl-2,3-dihydroquinolin-6-yl)ethynyl]benzoic acid, Cellular retinoic acid-binding protein 2, ... | Authors: | Tomlinson, C, Chisholm, D, Whiting, A, Pohl, E. | Deposit date: | 2018-09-07 | Release date: | 2018-11-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Novel Fluorescence Competition Assay for Retinoic Acid Binding Proteins. ACS Med Chem Lett, 9, 2018
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2O03
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2R94
| Crystal Structure of KD(P)GA from T.tenax | Descriptor: | 2-Keto-3-deoxy-(6-phospho-)gluconate aldolase, PYRUVIC ACID | Authors: | Pauluhn, A, Pohl, E. | Deposit date: | 2007-09-12 | Release date: | 2008-03-18 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure and stereochemical studies of KD(P)G aldolase from Thermoproteus tenax. Proteins, 72, 2008
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5OGB
| Human Cellular Retinoic Acid Binding Protein II (CRABPII) with bound synthetic retinoid DC360. | Descriptor: | 4-[2-(4,4-dimethyl-1-propan-2-yl-quinolin-6-yl)ethynyl]benzoic acid, Cellular retinoic acid-binding protein 2 | Authors: | Chisholm, D, Tomlinson, C, Whiting, A, Pohl, E. | Deposit date: | 2017-07-12 | Release date: | 2018-10-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Fluorescent Retinoic Acid Analogues as Probes for Biochemical and Intracellular Characterization of Retinoid Signaling Pathways. Acs Chem.Biol., 14, 2019
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1M4J
| CRYSTAL STRUCTURE OF THE N-TERMINAL ADF-H DOMAIN OF MOUSE TWINFILIN ISOFORM-1 | Descriptor: | A6 gene product | Authors: | Paavilainen, V.O, Merckel, M.C, Falck, S, Ojala, P.J, Pohl, E, Wilmanns, M, Lappalainen, P. | Deposit date: | 2002-07-03 | Release date: | 2002-11-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Conservation Between the Actin Monomer-binding Sites of Twinfilin and Actin-depolymerizing Factor (ADF)/Cofilin J.Biol.Chem., 277, 2002
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1M5W
| 1.96 A Crystal Structure of Pyridoxine 5'-Phosphate Synthase in Complex with 1-deoxy-D-xylulose phosphate | Descriptor: | 1-DEOXY-D-XYLULOSE-5-PHOSPHATE, PHOSPHATE ION, Pyridoxal phosphate biosynthetic protein pdxJ | Authors: | Yeh, J.I, Du, S, Pohl, E, Cane, D.E. | Deposit date: | 2002-07-10 | Release date: | 2003-07-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Multistate Binding in Pyridoxine 5'-Phosphate Synthase: 1.96 A Crystal Structure in
Complex with 1-deoxy-D-xylulose phosphate Biochemistry, 41, 2002
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7AA1
| Structural comparison of cellular retinoic acid binding proteins I and II in the presence and absence of natural and synthetic ligands | Descriptor: | 4-[2-(5,5,8,8-tetramethyl-6,7-dihydroquinoxalin-2-yl)ethynyl]benzoic acid, Cellular retinoic acid-binding protein 2 | Authors: | Tomlinson, C.W.E, Cornish, K.A.S, Pohl, E. | Deposit date: | 2020-09-02 | Release date: | 2021-02-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Structure-functional relationship of cellular retinoic acid-binding proteins I and II interacting with natural and synthetic ligands. Acta Crystallogr D Struct Biol, 77, 2021
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7A9Y
| Structural comparison of cellular retinoic acid binding protein I and II in the presence and absence of natural and synthetic ligands | Descriptor: | Cellular retinoic acid-binding protein 1, GLYCEROL, MYRISTIC ACID, ... | Authors: | Tomlinson, C.W.E, Cornish, K.A.S, Pohl, E. | Deposit date: | 2020-09-02 | Release date: | 2021-02-17 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structure-functional relationship of cellular retinoic acid-binding proteins I and II interacting with natural and synthetic ligands. Acta Crystallogr D Struct Biol, 77, 2021
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7A9Z
| Structural comparison of cellular retinoic acid binding protein I and II in the presence and absence of natural and synthetic ligands | Descriptor: | 4-[2-(5,5,8,8-tetramethyl-6,7-dihydroquinoxalin-2-yl)ethynyl]benzoic acid, Cellular retinoic acid-binding protein 1 | Authors: | Tomlinson, C.W.E, Cornish, K.A.S, Pohl, E. | Deposit date: | 2020-09-02 | Release date: | 2021-02-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Structure-functional relationship of cellular retinoic acid-binding proteins I and II interacting with natural and synthetic ligands. Acta Crystallogr D Struct Biol, 77, 2021
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7AA0
| Structural comparison of cellular retinoic acid binding protein I and II in the presence and absence of natural and synthetic ligands | Descriptor: | (~{E})-3-[4-(4,4-dimethyl-1-propan-2-yl-2,3-dihydroquinolin-6-yl)phenyl]prop-2-enoic acid, Cellular retinoic acid-binding protein 2 | Authors: | Tomlinson, C.W.E, Cornish, K.A.S, Pohl, E. | Deposit date: | 2020-09-02 | Release date: | 2021-02-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Structure-functional relationship of cellular retinoic acid-binding proteins I and II interacting with natural and synthetic ligands. Acta Crystallogr D Struct Biol, 77, 2021
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1OK4
| Archaeal fructose 1,6-bisphosphate aldolase covalently bound to the substrate dihydroxyacetone phosphate | Descriptor: | 1,3-DIHYDROXYACETONEPHOSPHATE, FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS I | Authors: | Lorentzen, E, Zwart, P, Stark, A, Hensel, R, Siebers, B, Pohl, E. | Deposit date: | 2003-07-17 | Release date: | 2003-09-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of an archaeal class I aldolase and the evolution of (betaalpha)8 barrel proteins. J. Biol. Chem., 278, 2003
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1OK6
| Orthorhombic crystal form of an Archaeal fructose 1,6-bisphosphate aldolase | Descriptor: | FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS I, GLYCEROL | Authors: | Lorentzen, E, Zwart, P, Stark, A, Hensel, R, Siebers, B, Pohl, E. | Deposit date: | 2003-07-18 | Release date: | 2003-09-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of an archaeal class I aldolase and the evolution of (betaalpha)8 barrel proteins. J. Biol. Chem., 278, 2003
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1UXQ
| Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax | Descriptor: | 1-O-phosphono-alpha-D-glucopyranose, GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (NADP+), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Lorentzen, E, Hensel, R, Pohl, E. | Deposit date: | 2004-03-01 | Release date: | 2004-08-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax J.Mol.Biol., 341, 2004
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1W0M
| Triosephosphate isomerase from Thermoproteus tenax | Descriptor: | PHOSPHATE ION, TRIOSEPHOSPHATE ISOMERASE | Authors: | Walden, H, Taylor, G, Lorentzen, E, Pohl, E, Lilie, H, Schramm, A, Knura, T, Stubbe, K, Tjaden, B, Hensel, R. | Deposit date: | 2004-06-08 | Release date: | 2004-09-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure and Function of a Regulated Archaeal Triosephosphate Isomerase Adapted to High Temperature J.Mol.Biol., 342, 2004
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4CYA
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1OJX
| Crystal structure of an Archaeal fructose 1,6-bisphosphate aldolase | Descriptor: | FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS I | Authors: | Lorentzen, E, Zwart, P, Stark, A, Hensel, R, Siebers, B, Pohl, E. | Deposit date: | 2003-07-16 | Release date: | 2003-09-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of an archaeal class I aldolase and the evolution of (betaalpha)8 barrel proteins. J. Biol. Chem., 278, 2003
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1W8S
| The mechanism of the Schiff Base Forming Fructose-1,6-bisphosphate Aldolase: Structural analysis of reaction intermediates | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS I | Authors: | Lorentzen, E, Hensel, R, Siebers, B, Pohl, E. | Deposit date: | 2004-09-27 | Release date: | 2005-03-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Mechanism of the Schiff base forming fructose-1,6-bisphosphate aldolase: structural analysis of reaction intermediates. Biochemistry, 44, 2005
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1UXN
| Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax | Descriptor: | ADENOSINE MONOPHOSPHATE, GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (NADP+), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Lorentzen, E, Hensel, R, Pohl, E. | Deposit date: | 2004-02-27 | Release date: | 2004-08-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax J.Mol.Biol., 341, 2004
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