2QZX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qzx by Molmil](/molmil-images/mine/2qzx) | Secreted aspartic proteinase (Sap) 5 from Candida albicans | Descriptor: | Candidapepsin-5, Pepstatin | Authors: | Lee, J.H, Ruge, E, Borelli, C, Maskos, K, Huber, R. | Deposit date: | 2007-08-17 | Release date: | 2008-07-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-ray structures of Sap1 and Sap5: Structural comparison of the secreted aspartic proteinases from Candida albicans. Proteins, 72, 2008
|
|
5H3H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h3h by Molmil](/molmil-images/mine/5h3h) | Esterase (EaEST) from Exiguobacterium antarcticum | Descriptor: | Abhydrolase domain-containing protein, ETHANEPEROXOIC ACID | Authors: | Lee, J.H, Lee, C.W. | Deposit date: | 2016-10-24 | Release date: | 2017-01-11 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structure and Functional Characterization of an Esterase (EaEST) from Exiguobacterium antarcticum. Plos One, 12, 2017
|
|
1HOX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hox by Molmil](/molmil-images/mine/1hox) | CRYSTAL STRUCTURE OF RABBIT PHOSPHOGLUCOSE ISOMERASE COMPLEXED WITH FRUCTOSE-6-PHOSPHATE | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, PHOSPHOGLUCOSE ISOMERASE | Authors: | Jeffrey, C.J, Lee, J.H, Chang, K.Z, Patel, V. | Deposit date: | 2000-12-11 | Release date: | 2001-07-20 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of rabbit phosphoglucose isomerase complexed with its substrate D-fructose 6-phosphate. Biochemistry, 40, 2001
|
|
3QID
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qid by Molmil](/molmil-images/mine/3qid) | Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase | Descriptor: | GLYCEROL, MANGANESE (III) ION, RNA dependent RNA polymerase, ... | Authors: | Kim, K.H, Intekhab, A, Lee, J.H. | Deposit date: | 2011-01-27 | Release date: | 2011-12-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase. J.Gen.Virol., 92, 2011
|
|
8G36
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g36 by Molmil](/molmil-images/mine/8g36) | Crystal structure of F182L-CYP199A4 in complex with terephthalic acid | Descriptor: | CHLORIDE ION, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Lee, J.H.Z, Bruning, J.B, Bell, S.G. | Deposit date: | 2023-02-06 | Release date: | 2023-05-17 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Engineering C-C Bond Cleavage Activity into a P450 Monooxygenase Enzyme. J.Am.Chem.Soc., 145, 2023
|
|
8G35
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g35 by Molmil](/molmil-images/mine/8g35) | Crystal structure of F182L-CYP199A4 in complex with (S)-4-(2-hydroxy-3-oxobutan-2-yl)benzoic acid | Descriptor: | 4-[(2S)-2-hydroxy-3-oxobutan-2-yl]benzoic acid, CHLORIDE ION, Cytochrome P450, ... | Authors: | Lee, J.H.Z, Bell, S.G, Bruning, J.B. | Deposit date: | 2023-02-06 | Release date: | 2023-05-17 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Engineering C-C Bond Cleavage Activity into a P450 Monooxygenase Enzyme. J.Am.Chem.Soc., 145, 2023
|
|
7JW5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jw5 by Molmil](/molmil-images/mine/7jw5) | Crystal structure of WT-CYP199A4 in complex with 4-phenylbenzoic acid | Descriptor: | CHLORIDE ION, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Lee, J.H.Z, Bruning, J.B, Bell, S.G. | Deposit date: | 2020-08-24 | Release date: | 2021-09-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.526 Å) | Cite: | Different Geometric Requirements for Cytochrome P450-Catalyzed Aliphatic Versus Aromatic Hydroxylation Results in Chemoselective Oxidation Acs Catalysis, 12, 2022
|
|
3EGM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3egm by Molmil](/molmil-images/mine/3egm) | Structural basis of iron transport gating in Helicobacter pylori ferritin | Descriptor: | FE (III) ION, Ferritin, GLYCEROL | Authors: | Kim, K.H, Cho, K.J, Shin, H.J, Lee, J.H. | Deposit date: | 2008-09-11 | Release date: | 2009-07-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of ferritin from Helicobacter pylori reveals unusual conformational changes for iron uptake. J.Mol.Biol., 390, 2009
|
|
8WFC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8wfc by Molmil](/molmil-images/mine/8wfc) | |
3NAH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nah by Molmil](/molmil-images/mine/3nah) | Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase | Descriptor: | RNA dependent RNA polymerase, SULFATE ION | Authors: | Kim, K.H, Lee, J.H, Alam, I, Park, Y, Kang, S. | Deposit date: | 2010-06-02 | Release date: | 2011-06-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase To be Published
|
|
3NAI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nai by Molmil](/molmil-images/mine/3nai) | Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase | Descriptor: | 5-FLUOROURACIL, GLYCEROL, MAGNESIUM ION, ... | Authors: | Kim, K.H, Lee, J.H, Alam, I, Park, Y, Kang, S. | Deposit date: | 2010-06-02 | Release date: | 2011-06-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase To be Published
|
|
7C04
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7c04 by Molmil](/molmil-images/mine/7c04) | Crystal structure of human Trap1 with DN203492 | Descriptor: | 4-chloranyl-1-[[2-methoxy-4-(trifluoromethyl)phenyl]methyl]pyrazolo[3,4-d]pyrimidin-6-amine, Heat shock protein 75 kDa, mitochondrial | Authors: | Kim, D, Kim, D, Kim, S.Y, Lee, J.H, Kang, B.H, Kang, S, Lee, C. | Deposit date: | 2020-04-30 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models. Bioorg.Chem., 101, 2020
|
|
7C05
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7c05 by Molmil](/molmil-images/mine/7c05) | Crystal structure of human Trap1 with DN203495 | Descriptor: | 1-[(4-bromanyl-2-fluoranyl-phenyl)methyl]-4-chloranyl-pyrazolo[3,4-d]pyrimidin-6-amine, Heat shock protein 75 kDa, mitochondrial | Authors: | Kim, D, Kim, D, Kim, S.Y, Lee, J.H, Kang, B.H, Kang, S, Lee, C. | Deposit date: | 2020-04-30 | Release date: | 2020-07-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models. Bioorg.Chem., 101, 2020
|
|
4EDA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4eda by Molmil](/molmil-images/mine/4eda) | Structures of monomeric hemagglutinin and its complex with an Fab fragment of a neutralizing antibody that binds to H1 subtype influenza viruses: molecular basis of infectivity of 2009 pandemic H1N1 influenza A viruses | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | Authors: | Kim, K.H, Cho, K.J, Lee, J.H, Park, Y.H, Khan, T.G, Lee, J.Y, Kang, S.H, Alam, I. | Deposit date: | 2012-03-27 | Release date: | 2013-05-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.701 Å) | Cite: | Insight into structural diversity of influenza virus haemagglutinin J.Gen.Virol., 94, 2013
|
|
4EDB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4edb by Molmil](/molmil-images/mine/4edb) | Structures of monomeric hemagglutinin and its complex with an Fab fragment of a neutralizing antibody that binds to H1 subtype influenza viruses: molecular basis of infectivity of 2009 pandemic H1N1 influenza A viruses | Descriptor: | Hemagglutinin | Authors: | Kim, K.H, Cho, K.J, Lee, J.H, Park, Y.H, Khan, T.G, Lee, J.Y, Kang, S.H, Alam, I. | Deposit date: | 2012-03-27 | Release date: | 2013-05-22 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Insight into structural diversity of influenza virus haemagglutinin J.Gen.Virol., 94, 2013
|
|
5X3F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5x3f by Molmil](/molmil-images/mine/5x3f) | Crystal structure of the YgjG-Protein A-Zpa963-PKA catalytic domain | Descriptor: | Putrescine aminotransferase,Immunoglobulin G-binding protein A, Zpa963,cAMP-dependent protein kinase catalytic subunit alpha | Authors: | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | Deposit date: | 2017-02-05 | Release date: | 2017-06-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.38 Å) | Cite: | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method. Sci Rep, 7, 2017
|
|
5XBY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xby by Molmil](/molmil-images/mine/5xby) | Crystal structure of the PKA-Protein A fusion protein (end-to-end fusion) | Descriptor: | cAMP-dependent protein kinase type II-alpha regulatory subunit,Immunoglobulin G-binding protein A | Authors: | Youn, S.J, Kwon, N.Y, Lee, J.H, Kim, J.H, Lee, H, Lee, J.O. | Deposit date: | 2017-03-21 | Release date: | 2017-07-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Construction of novel repeat proteins with rigid and predictable structures using a shared helix method. Sci Rep, 7, 2017
|
|
8HGU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hgu by Molmil](/molmil-images/mine/8hgu) | |
8HM5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hm5 by Molmil](/molmil-images/mine/8hm5) | |
8HG9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hg9 by Molmil](/molmil-images/mine/8hg9) | Cytochrome P450 steroid hydroxylase (BaCYP106A6) from Bacillus species | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 steroid hydroxylase | Authors: | Do, H, Lee, J.H. | Deposit date: | 2022-11-14 | Release date: | 2023-07-26 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Crystal Structure and Biochemical Analysis of a Cytochrome P450 Steroid Hydroxylase ( Ba CYP106A6) from Bacillus Species. J Microbiol Biotechnol., 33, 2023
|
|
5Y7W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y7w by Molmil](/molmil-images/mine/5y7w) | Crystal structure of the Nco-A1 PAS-B domain with YL-2 | Descriptor: | Nuclear receptor coactivator 1, YL-2 peptide | Authors: | Lee, Y.J, Yoon, H.S, Lee, J.H, Bae, J.H, Song, J.Y, Lim, H.S. | Deposit date: | 2017-08-18 | Release date: | 2017-11-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Targeted Inhibition of the NCOA1/STAT6 Protein-Protein Interaction J. Am. Chem. Soc., 139, 2017
|
|
5YX3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yx3 by Molmil](/molmil-images/mine/5yx3) | |
4F15
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4f15 by Molmil](/molmil-images/mine/4f15) | Molecular basis of infectivity of 2009 pandemic H1N1 influenza A viruses | Descriptor: | Fab fragment, heavy chain, light chain, ... | Authors: | Kim, K.H, Cho, K.J, Lee, J.H, Park, Y.H, Khan, T.G, Lee, J.Y, Kang, S.H, Alam, I. | Deposit date: | 2012-05-06 | Release date: | 2013-05-15 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Molecular basis of infectivity of 2009 pandemic H1N1 influenza A viruses To be Published
|
|
5YX4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yx4 by Molmil](/molmil-images/mine/5yx4) | Isoliquiritigenin-complexed Chalcone isomerase (S189A) from the Antarctic vascular plant Deschampsia Antarctica (DaCHI1) | Descriptor: | 2',4,4'-TRIHYDROXYCHALCONE, Chalcone-flavonone isomerase family protein | Authors: | Lee, C.W, Park, S, Lee, J.H. | Deposit date: | 2017-12-01 | Release date: | 2018-02-14 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure and enzymatic properties of chalcone isomerase from the Antarctic vascular plant Deschampsia antarctica Desv. PLoS ONE, 13, 2018
|
|
6A7J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6a7j by Molmil](/molmil-images/mine/6a7j) | Testerone bound CYP154C4 from Streptomyces sp. ATCC 11861 | Descriptor: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, TESTOSTERONE | Authors: | Lee, C.W, Lee, J.H. | Deposit date: | 2018-07-03 | Release date: | 2019-01-16 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Characterization of two steroid hydroxylases from different Streptomyces spp. and their ligand-bound and -unbound crystal structures. Febs J., 286, 2019
|
|