4HIS
 
 | | The Structure of V122I Mutant Transthyretin in Complex with Tafamidis | | Descriptor: | 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin | | Authors: | Connelly, S, Alhamadsheh, M, Graef, I, Wilson, I.A. | | Deposit date: | 2012-10-11 | | Release date: | 2013-06-05 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin.
Proc.Natl.Acad.Sci.USA, 110, 2013
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6E7G
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6CK8
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1IGF
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1GRC
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1HIM
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1HIL
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1GND
 | | GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, ALPHA-ISOFORM | | Descriptor: | GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR | | Authors: | Schalk, I, Zeng, K, Wu, S.-K, Stura, E.A, Metteson, J, Huang, M, Tandon, A, Wilson, I.A, Balch, W.E. | | Deposit date: | 1996-07-10 | | Release date: | 1997-02-12 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.81 Å) | | Cite: | Structure and mutational analysis of Rab GDP-dissociation inhibitor.
Nature, 381, 1996
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1HIN
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1KJV
 | | TAP-B-associated rat MHC class I molecule | | Descriptor: | Mature alpha chain of major histocompatibility complex class I antigen (HEAVY CHAIN), SULFATE ION, beta-2-microglobulin, ... | | Authors: | Rudolph, M.G, Stevens, J, Speir, J.A, Trowsdale, J, Butcher, G.W, Joly, E, Wilson, I.A. | | Deposit date: | 2001-12-05 | | Release date: | 2002-12-18 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | Crystal structures of two rat MHC class Ia (RT1-A) molecules that are associated differentially
with peptide transporter alleles TAP-A and TAP-B.
J.Mol.Biol., 324, 2002
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1KPV
 | | High resolution crystal structure of the MHC class I complex H-2Kb/SEV9 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 class I histocompatibility antigen, ... | | Authors: | Rudolph, M.G, Wilson, I.A. | | Deposit date: | 2002-01-02 | | Release date: | 2003-06-10 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | High Resolution Crystal Structure of H-2Kb/VSV8
To be Published
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9B82
 | | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody COVA2-15 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA2-15 antibody heavy chain, COVA2-15 antibody light chain, ... | | Authors: | Yuan, M, Zhu, X, Wilson, I.A. | | Deposit date: | 2024-03-28 | | Release date: | 2024-12-04 | | Last modified: | 2025-01-08 | | Method: | X-RAY DIFFRACTION (3.38 Å) | | Cite: | Plant-produced SARS-CoV-2 antibody engineered towards enhanced potency and in vivo efficacy.
Plant Biotechnol J, 23, 2025
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9BDI
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9BDH
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4ZCJ
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9C7D
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9C79
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9C7F
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9C22
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9DIO
 | | Crystal structure of H5 hemagglutinin Q226L mutant from the influenza virus A/Texas/37/2024 (H5N1) with LSTc | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | | Authors: | Lin, T.H, Zhu, Y, Wilson, I.A. | | Deposit date: | 2024-09-05 | | Release date: | 2024-12-04 | | Last modified: | 2025-01-22 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors.
Science, 386, 2024
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9DIQ
 | | Crystal structure of Apo-H5 hemagglutinin from the influenza virus A/Texas/37/2024 (H5N1) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | | Authors: | Lin, T.H, Zhu, Y, Wilson, I.A. | | Deposit date: | 2024-09-05 | | Release date: | 2024-12-04 | | Last modified: | 2025-01-22 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors.
Science, 386, 2024
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9DIP
 | | Crystal structure of H5 hemagglutinin from the influenza virus A/Texas/37/2024 (H5N1) with LSTa | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ... | | Authors: | Lin, T.H, Zhu, Y, Wilson, I.A. | | Deposit date: | 2024-09-05 | | Release date: | 2024-12-04 | | Last modified: | 2025-01-22 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors.
Science, 386, 2024
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5C7K
 | | Crystal structure BG505 SOSIP gp140 HIV-1 Env trimer bound to broadly neutralizing antibodies PGT128 and 8ANC195 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab 8ANC195 heavy chain, ... | | Authors: | Kong, L, Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2015-06-24 | | Release date: | 2015-10-07 | | Last modified: | 2024-12-25 | | Method: | X-RAY DIFFRACTION (4.6019 Å) | | Cite: | Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer.
Acta Crystallogr.,Sect.D, 71, 2015
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5BZD
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5CCK
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