4NJV
 
 | | Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with ritonavir | | Descriptor: | Protease, RITONAVIR | | Authors: | Yedidi, R.S, Garimella, H, Chang, S.B, Kaufman, J.D, Das, D, Wingfield, P.T, Mitsuya, H. | | Deposit date: | 2013-11-11 | | Release date: | 2014-04-02 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A Conserved Hydrogen-Bonding Network of P2 bis-Tetrahydrofuran-Containing HIV-1 Protease Inhibitors (PIs) with a Protease Active-Site Amino Acid Backbone Aids in Their Activity against PI-Resistant HIV.
Antimicrob.Agents Chemother., 58, 2014
|
|
4NJT
 | | Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with darunavir | | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Protease | | Authors: | Yedidi, R.S, Garimella, H, Chang, S.B, Kaufman, J.D, Das, D, Wingfield, P.T, Ghosh, A.K, Mitsuya, H. | | Deposit date: | 2013-11-11 | | Release date: | 2014-04-02 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | A Conserved Hydrogen-Bonding Network of P2 bis-Tetrahydrofuran-Containing HIV-1 Protease Inhibitors (PIs) with a Protease Active-Site Amino Acid Backbone Aids in Their Activity against PI-Resistant HIV.
Antimicrob.Agents Chemother., 58, 2014
|
|
1QBZ
 | | THE CRYSTAL STRUCTURE OF THE SIV GP41 ECTODOMAIN AT 1.47 A | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, CHLORIDE ION, MERCURY (II) ION, ... | | Authors: | Yang, Z.-N, Mueser, T.C, Kaufman, J, Stahl, S.J, Wingfield, P.T, Hyde, C.C. | | Deposit date: | 1999-04-28 | | Release date: | 1999-05-17 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (1.47 Å) | | Cite: | The crystal structure of the SIV gp41 ectodomain at 1.47 A resolution.
J.Struct.Biol., 126, 1999
|
|
1EY1
 | | SOLUTION STRUCTURE OF ESCHERICHIA COLI NUSB | | Descriptor: | ANTITERMINATION FACTOR NUSB | | Authors: | Altieri, A.S, Mazzulla, M.J, Horita, D.A, Coats, R.H, Wingfield, P.T, Byrd, R.A. | | Deposit date: | 2000-05-05 | | Release date: | 2000-06-14 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The structure of the transcriptional antiterminator NusB from Escherichia coli.
Nat.Struct.Biol., 7, 2000
|
|
6I1B
 | |
7I1B
 | |
4TRX
 | |
3TRX
 | |
2JR0
 | | Solution structure of NusB from Aquifex Aeolicus | | Descriptor: | N utilization substance protein B homolog | | Authors: | Das, R, Loss, S, Li, J, Tarasov, S, Wingfield, P, Waugh, D.S, Byrd, R.A, Altieri, A.S. | | Deposit date: | 2007-06-18 | | Release date: | 2008-02-19 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Structural biophysics of the NusB:NusE antitermination complex.
J.Mol.Biol., 376, 2008
|
|
8VJN
 | |
8VJO
 | |
2EZQ
 | |
2EZP
 | |
2EZS
 | |
2EZO
 | |
2EZR
 | |
7U0F
 | | HIV-1 Rev in complex with tubulin | | Descriptor: | Protein Rev, Tubulin alpha-1A chain, Tubulin beta chain | | Authors: | Eren, E. | | Deposit date: | 2022-02-18 | | Release date: | 2023-08-23 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3.53 Å) | | Cite: | Structural basis of microtubule depolymerization by the kinesin-like activity of HIV-1 Rev.
Structure, 31, 2023
|
|
5V4Y
 | | X-ray crystal structure of wild type HIV-1 protease in complex with GRL-09510 | | Descriptor: | (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate, Protease | | Authors: | Yedidi, R.S, Delino, N.S, Das, D, Kaufman, J.D, Wingfield, P.T, Ghosh, A.K, Mitsuya, H. | | Deposit date: | 2017-03-11 | | Release date: | 2017-09-13 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | GRL-09510, a Unique P2-Crown-Tetrahydrofuranylurethane -Containing HIV-1 Protease Inhibitor, Maintains Its Favorable Antiviral Activity against Highly-Drug-Resistant HIV-1 Variants in vitro.
Sci Rep, 7, 2017
|
|
1QA5
 | |
1QA4
 | |
1QCE
 | |
2NVH
 | |
7M18
 | | HeLa-tubulin in complex with cryptophycin 1 | | Descriptor: | Cryptophycin 1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Eren, E. | | Deposit date: | 2021-03-12 | | Release date: | 2021-09-08 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.38 Å) | | Cite: | Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action.
J.Biol.Chem., 297, 2021
|
|
7M20
 | | 18-mer HeLa-tubulin rings in complex with Cryptophycin 1 | | Descriptor: | Cryptophycin 1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Eren, E. | | Deposit date: | 2021-03-15 | | Release date: | 2021-09-08 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.84 Å) | | Cite: | Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action.
J.Biol.Chem., 297, 2021
|
|
7LXB
 | | HeLa-tubulin in complex with cryptophycin 52 | | Descriptor: | Cryptophycin 52, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Eren, E. | | Deposit date: | 2021-03-03 | | Release date: | 2021-09-08 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | Conformational changes in tubulin upon binding cryptophycin-52 reveal its mechanism of action.
J.Biol.Chem., 297, 2021
|
|
