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1YJD
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BU of 1yjd by Molmil
Crystal structure of human CD28 in complex with the Fab fragment of a mitogenic antibody (5.11A1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab fragment of 5.11A1 antibody heavy chain, Fab fragment of 5.11A1 antibody light chain, ...
Authors:Evans, E.J, Esnouf, R.M, Manso-Sancho, R, Gilbert, R.J.C, James, J.R, Sorensen, P, Stuart, D.I, Davis, S.J.
Deposit date:2005-01-14
Release date:2005-02-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of a soluble CD28-Fab complex
Nat.Immunol., 6, 2005
6EON
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BU of 6eon by Molmil
Galactanase BT0290
Descriptor: Beta-galactosidase, CALCIUM ION, alpha-D-galactopyranose
Authors:Basle, A, Munoz, J, Gilbert, H.
Deposit date:2017-10-10
Release date:2017-11-29
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation.
Nat Microbiol, 3, 2018
6EUI
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BU of 6eui by Molmil
The GH43, Beta 1,3 Galactosidase, BT3683 with galactose
Descriptor: Beta-glucanase, CALCIUM ION, beta-D-galactopyranose
Authors:Cartmell, A, Gilbert, H.J.
Deposit date:2017-10-30
Release date:2018-10-17
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation.
Nat Microbiol, 3, 2018
6EUJ
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BU of 6euj by Molmil
The GH43, Beta 1,3 Galactosidase, BT0265
Descriptor: Beta-glucanase
Authors:Cartmell, A, Gilbert, H.J.
Deposit date:2017-10-30
Release date:2018-10-17
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation.
Nat Microbiol, 3, 2018
6EUF
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BU of 6euf by Molmil
The GH43, Beta 1,3 Galactosidase, BT0265
Descriptor: Beta-glucanase, alpha-L-arabinofuranose-(1-3)-[alpha-L-arabinofuranose-(1-4)][beta-D-glucopyranuronic acid-(1-6)]beta-D-galactopyranose-(1-6)-beta-D-galactopyranose, alpha-L-rhamnopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-6)-[alpha-L-arabinofuranose-(1-3)][alpha-L-arabinofuranose-(1-4)]beta-D-galactopyranose-(1-6)-beta-D-galactopyranose
Authors:Cartmell, A, Gilbert, H.J.
Deposit date:2017-10-30
Release date:2018-10-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation.
Nat Microbiol, 3, 2018
6EUH
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BU of 6euh by Molmil
The GH43, Beta 1,3 Galactosidase, BT3683 with galactodeoxynojirimycin
Descriptor: (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, Beta-glucanase, CALCIUM ION
Authors:Cartmell, A, Gilbert, H.J.
Deposit date:2017-10-30
Release date:2018-10-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation.
Nat Microbiol, 3, 2018
6EUG
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BU of 6eug by Molmil
The GH43, Beta 1,3 Galactosidase, BT3683 with galactoimidazole
Descriptor: Beta-glucanase, GLUCOIMIDAZOLE
Authors:Cartmell, A, Gilbert, H.J.
Deposit date:2017-10-30
Release date:2018-10-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation.
Nat Microbiol, 3, 2018
8AA3
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BU of 8aa3 by Molmil
Core SusCD transporter units from the inactive levan utilisome in the presence of levan fructo-oligosaccharides DP 15-25
Descriptor: MAGNESIUM ION, SusC homolog, SusD homolog, ...
Authors:White, J.B.R, Silale, A, Ranson, N.A, van den Berg, B.
Deposit date:2022-06-29
Release date:2023-06-07
Last modified:2023-06-21
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Outer membrane utilisomes mediate glycan uptake in gut Bacteroidetes.
Nature, 618, 2023
8A9Y
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BU of 8a9y by Molmil
Substrate-free levan utilisation machinery (utilisome)
Descriptor: DUF4960 domain-containing protein, Glycoside hydrolase family 32, MAGNESIUM ION, ...
Authors:White, J.B.R, Silale, A, Ranson, N.A, van den Berg, B.
Deposit date:2022-06-29
Release date:2023-06-07
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Outer membrane utilisomes mediate glycan uptake in gut Bacteroidetes.
Nature, 618, 2023
8AA4
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BU of 8aa4 by Molmil
SusC components of the dextran utilisation system (utilisome)
Descriptor: SusC homolog
Authors:White, J.B.R, Silale, A, Ranson, N.A, van den Berg, B.
Deposit date:2022-06-29
Release date:2023-06-07
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Outer membrane utilisomes mediate glycan uptake in gut Bacteroidetes.
Nature, 618, 2023
8AA1
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BU of 8aa1 by Molmil
Core SusCD transporter units from the levan utilisome with levan fructo-oligosaccharides DP 8-12
Descriptor: MAGNESIUM ION, SusC homolog, SusD homolog, ...
Authors:White, J.B.R, Silale, A, Ranson, N.A, van den Berg, B.
Deposit date:2022-06-29
Release date:2023-06-07
Last modified:2023-06-21
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Outer membrane utilisomes mediate glycan uptake in gut Bacteroidetes.
Nature, 618, 2023
8AA0
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BU of 8aa0 by Molmil
Levan utilisation machinery (utilisome) with levan fructo-oligosaccharides DP 8-12
Descriptor: DUF4960 domain-containing protein, Glycoside hydrolase family 32, MAGNESIUM ION, ...
Authors:White, J.B.R, Silale, A, Ranson, N.A, van den Berg, B.
Deposit date:2022-06-29
Release date:2023-06-07
Last modified:2023-06-21
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Outer membrane utilisomes mediate glycan uptake in gut Bacteroidetes.
Nature, 618, 2023
8AA2
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BU of 8aa2 by Molmil
Inactive levan utilisation machinery (utilisome) in the presence of levan fructo-oligosaccharides DP 15-25
Descriptor: DUF4960 domain-containing protein, Glycoside hydrolase family 32, MAGNESIUM ION, ...
Authors:White, J.B.R, Silale, A, Ranson, N.A, van den Berg, B.
Deposit date:2022-06-29
Release date:2023-06-07
Last modified:2023-06-21
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Outer membrane utilisomes mediate glycan uptake in gut Bacteroidetes.
Nature, 618, 2023
7ZNR
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BU of 7znr by Molmil
Inactive D62N mutant of BT1760 Endo-acting levanase from Bacteroides thetaiotaomicron VPI-5482
Descriptor: SULFATE ION, Sucrose-6-phosphate hydrolase, beta-D-fructofuranose-(2-6)-beta-D-fructofuranose, ...
Authors:Basle, A, Bolam, D.
Deposit date:2022-04-21
Release date:2023-06-21
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Outer membrane utilisomes mediate glycan uptake in gut Bacteroidetes.
Nature, 618, 2023
7ZNS
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BU of 7zns by Molmil
Inactive D62N mutant of BT1760 Endo-acting levanase from Bacteroides thetaiotaomicron VPI-5482
Descriptor: Glycoside hydrolase family 32, SULFATE ION, beta-D-fructofuranose-(2-6)-beta-D-fructofuranose, ...
Authors:Basle, A, Bolam, D.
Deposit date:2022-04-21
Release date:2023-06-21
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Outer membrane utilisomes mediate glycan uptake in gut Bacteroidetes.
Nature, 618, 2023
3PP1
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BU of 3pp1 by Molmil
Crystal Structure of the Human Mitogen-activated protein kinase kinase 1 (MEK 1) in complex with ligand and MgATP
Descriptor: 3-[(2R)-2,3-dihydroxypropyl]-6-fluoro-5-[(2-fluoro-4-iodophenyl)amino]-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione, ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Dougan, D.R.
Deposit date:2010-11-23
Release date:2011-02-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery of TAK-733, a potent and selective MEK allosteric site inhibitor for the treatment of cancer.
Bioorg.Med.Chem.Lett., 21, 2011
3P23
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BU of 3p23 by Molmil
Crystal structure of the Human kinase and RNase domains in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SULFATE ION, ...
Authors:Ali, M.M.U, Pearl, L.H.
Deposit date:2010-10-01
Release date:2011-02-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response.
Embo J., 30, 2011
4Z3V
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BU of 4z3v by Molmil
Fragment-Based Discovery of a Small Molecule Reversible Inhibitor of Bruton's Tyrosine Kinase
Descriptor: 1,2-ETHANEDIOL, 4-amino-8-(5-methyl-1H-indazol-6-yl)cinnoline-3-carboxamide, IMIDAZOLE, ...
Authors:Dougan, D.R.
Deposit date:2015-03-31
Release date:2015-07-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Fragment-Based Discovery of a Small Molecule Inhibitor of Bruton's Tyrosine Kinase.
J.Med.Chem., 58, 2015
4ZLZ
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BU of 4zlz by Molmil
Crystal Structure of Bruton's Tyrosine Kinase in complex with a substituted Cinnoline
Descriptor: 4-amino-8-(4-methylpyridin-3-yl)cinnoline-3-carboxamide, DIMETHYL SULFOXIDE, IMIDAZOLE, ...
Authors:Dougan, D.R.
Deposit date:2015-05-01
Release date:2015-07-01
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Fragment-Based Discovery of a Small Molecule Inhibitor of Bruton's Tyrosine Kinase.
J.Med.Chem., 58, 2015
3MBL
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BU of 3mbl by Molmil
Crystal Structure of the human mitogen-activated protein kinase kinase 1 (MEK 1) in complex with ligand and MgADP
Descriptor: 5-acetyl-2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-1-methyl-1H-pyrrole-3-carboxamide, ADENOSINE-5'-DIPHOSPHATE, Dual specificity mitogen-activated protein kinase kinase 1, ...
Authors:Dougan, D.R, Mol, C.D.
Deposit date:2010-03-25
Release date:2010-07-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-based design and synthesis of pyrrole derivatives as MEK inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
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