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2H53
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BU of 2h53 by Molmil
Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26
Descriptor: small heat shock protein Hsp26
Authors:White, H.E, Orlova, E.V, Chen, S, Wang, L, Ignatiou, A, Gowen, B, Stromer, T, Franzmann, T.M, Haslbeck, M, Buchner, J, Saibil, H.R.
Deposit date:2006-05-25
Release date:2006-08-01
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein hsp26
Structure, 14, 2006
6QS8
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BU of 6qs8 by Molmil
ClpB (DWB and K476C mutant) bound to casein in presence of ATPgammaS - state KC-2B
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, MAGNESIUM ION, ...
Authors:Deville, C, Saibil, H.R.
Deposit date:2019-02-20
Release date:2019-07-03
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.
Cell Rep, 27, 2019
6QS4
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BU of 6qs4 by Molmil
Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Deville, C, Saibil, H.R.
Deposit date:2019-02-20
Release date:2019-07-03
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.
Cell Rep, 27, 2019
6QS7
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BU of 6qs7 by Molmil
ClpB (DWB and K476C mutant) bound to casein in presence of ATPgammaS - state KC-2A
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, MAGNESIUM ION, ...
Authors:Deville, C, Saibil, H.R.
Deposit date:2019-02-20
Release date:2019-07-03
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor.
Cell Rep, 27, 2019
8B6U
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BU of 8b6u by Molmil
Mpf2Ba1 monomer
Descriptor: MAGNESIUM ION, Mpf2Ba1
Authors:Marini, G, Poland, B, Leininger, C, Lukoyanova, N, Spielbauer, D, Barry, J, Altier, D, Lum, A, Scolaro, E, Perez-Ortega, C, Yalpani, N, Sandahl, G, Mabry, T, Klever, J, Nowatzki, T, Zhao, J.Z, Sethi, A, Kassa, A, Crane, V, Lu, A, Nelson, M.E, Eswar, N, Topf, M, Saibil, H.R.
Deposit date:2022-09-27
Release date:2023-05-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.134 Å)
Cite:Structural journey of an insecticidal protein against western corn rootworm.
Nat Commun, 14, 2023
8B6W
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BU of 8b6w by Molmil
Mpf2Ba1 pore
Descriptor: MAGNESIUM ION, Mpf2Ba1
Authors:Marini, G, Poland, B, Leininger, C, Lukoyanova, N, Spielbauer, D, Barry, J, Altier, D, Lum, A, Scolaro, E, Perez Ortega, C, Yalpani, N, Sandahl, G, Mabry, T, Klever, J, Nowatzki, T, Zhao, J.Z, Sethi, A, Kassa, A, Crane, V, Lu, A, Nelson, M.E, Eswar, N, Topf, M, Saibil, H.R.
Deposit date:2022-09-27
Release date:2023-05-31
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural journey of an insecticidal protein against western corn rootworm.
Nat Commun, 14, 2023
8B6V
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BU of 8b6v by Molmil
Mp2Ba1 pre-pore
Descriptor: MAGNESIUM ION, Mpf2Ba1
Authors:Marini, G, Poland, B, Leininger, C, Lukoyanova, N, Spielbauer, D, Barry, J, Altier, D, Lum, A, Scolaro, E, Perez Ortega, C, Yalpani, N, Sandahl, G, Mabry, T, Klever, J, Nowatzki, T, Zhao, J.Z, Sethi, A, Kassa, A, Crane, V, Lu, A, Nelson, M.E, Eswar, N, Topf, M, Saibil, H.R.
Deposit date:2022-09-27
Release date:2023-05-31
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural journey of an insecticidal protein against western corn rootworm.
Nat Commun, 14, 2023
8BA7
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BU of 8ba7 by Molmil
CryoEM structure of nucleotide-free GroEL-Rubisco.
Descriptor: Chaperonin GroEL
Authors:Gardner, S, Saibil, H.R.
Deposit date:2022-10-11
Release date:2023-10-25
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural basis of substrate progression through the bacterial chaperonin cycle.
Proc.Natl.Acad.Sci.USA, 120, 2023
8BA8
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BU of 8ba8 by Molmil
CryoEM structure of GroEL-ADP.BeF3-Rubisco.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chaperonin GroEL, ...
Authors:Gardner, S, Saibil, H.R.
Deposit date:2022-10-11
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of substrate progression through the bacterial chaperonin cycle.
Proc Natl Acad Sci U S A, 120, 2023
8BA9
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BU of 8ba9 by Molmil
CryoEM structure of GroEL-GroES-ADP.AlF3-Rubisco.
Descriptor: 60 kDa chaperonin, ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ...
Authors:Gardner, S, Saibil, H.R.
Deposit date:2022-10-11
Release date:2023-12-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of substrate progression through the bacterial chaperonin cycle.
Proc Natl Acad Sci U S A, 120, 2023
1GRU
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BU of 1gru by Molmil
SOLUTION STRUCTURE OF GROES-ADP7-GROEL-ATP7 COMPLEX BY CRYO-EM
Descriptor: GROEL, GROES
Authors:Ranson, N.A, Farr, G.W, Roseman, A.M, Gowen, B, Fenton, W.A, Horwich, A.L, Saibil, H.R.
Deposit date:2001-12-16
Release date:2002-01-28
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (12.5 Å)
Cite:ATP-Bound States of Groel Captured by Cryo-Electron Microscopy.
Cell(Cambridge,Mass.), 107, 2001
1GR5
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BU of 1gr5 by Molmil
Solution Structure of apo GroEL by Cryo-Electron microscopy
Descriptor: 60 KDA CHAPERONIN
Authors:Ranson, N.A, Farr, G.W, Roseman, A.M, Gowen, B, Fenton, W.A, Horwich, A.L, Saibil, H.R.
Deposit date:2001-12-14
Release date:2002-01-28
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:ATP-Bound States of Groel Captured by Cryo-Electron Microscopy.
Cell(Cambridge,Mass.), 107, 2001
2BK1
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BU of 2bk1 by Molmil
The pore structure of pneumolysin, obtained by fitting the alpha carbon trace of perfringolysin O into a cryo-EM map
Descriptor: PERFRINGOLYSIN O
Authors:Tilley, S.J, Orlova, E.V, Gilbert, R.J.C, Andrew, P.W, Saibil, H.R.
Deposit date:2005-02-10
Release date:2005-05-04
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (29 Å)
Cite:Structural Basis of Pore Formation by the Bacterial Toxin Pneumolysin
Cell(Cambridge,Mass.), 121, 2005
2BYU
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BU of 2byu by Molmil
Negative stain EM reconstruction of M.tuberculosis Acr1(Hsp 16.3) fitted with wheat sHSP dimer
Descriptor: HEAT SHOCK PROTEIN 16.9B
Authors:Kennaway, C.K, Benesch, J.L.P, Gohlke, U, Wang, L, Robinson, C.V, Orlova, E.V, Saibil, H.R, Keep, N.H.
Deposit date:2005-08-05
Release date:2005-08-22
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (16.5 Å)
Cite:Dodecameric Structure of the Small Heat Shock Protein Acr1 from Mycobacterium Tuberculosis.
J.Biol.Chem., 280, 2005
2CGT
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BU of 2cgt by Molmil
GROEL-ADP-gp31 COMPLEX
Descriptor: 60 KDA GROEL, CAPSID ASSEMBLY PROTEIN GP31
Authors:Clare, D.K, Bakkes, P.J, van Heerikhuizen, H, van der Vies, S.M, Saibil, H.R.
Deposit date:2006-03-09
Release date:2006-03-29
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:An Expanded Protein Folding Cage in the Groel-Gp31 Complex.
J.Mol.Biol., 358, 2006
2C7E
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BU of 2c7e by Molmil
REVISED ATOMIC STRUCTURE FITTING INTO A GROEL(D398A)-ATP7 CRYO-EM MAP (EMD 1047)
Descriptor: 60 KDA CHAPERONIN, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Ranson, N.A, Farr, G.W, Roseman, A.M, Gowen, B, Fenton, W.A, Horwich, A.L, Saibil, H.R.
Deposit date:2005-11-22
Release date:2006-02-16
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (14.9 Å)
Cite:ATP-Bound States of Groel Captured by Cryo-Electron Microscopy
Cell(Cambridge,Mass.), 107, 2001
2C7D
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BU of 2c7d by Molmil
Fitted coordinates for GroEL-ADP7-GroES Cryo-EM complex (EMD-1181)
Descriptor: 10 KDA CHAPERONIN MOLECULE: GROES, PROTEIN CPN10, GROES PROTEIN, ...
Authors:Ranson, N.A, Clare, D.K, Farr, G.W, Houldershaw, D, Horwich, A.L, Saibil, H.R.
Deposit date:2005-11-22
Release date:2006-01-25
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Allosteric Signalling of ATP Hydrolysis in Groel-Groes Complexes.
Nat.Struct.Mol.Biol., 13, 2006
2C7C
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BU of 2c7c by Molmil
FITTED COORDINATES FOR GROEL-ATP7-GROES CRYO-EM COMPLEX (EMD-1180)
Descriptor: 10 KDA CHAPERONIN MOLECULE: GROES, PROTEIN CPN10, GROES PROTEIN, ...
Authors:Ranson, N.A, Clare, D.K, Farr, G.W, Houldershaw, D, Horwich, A.L, Saibil, H.R.
Deposit date:2005-11-22
Release date:2006-01-25
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Allosteric Signalling of ATP Hydrolysis in Groel-Groes Complexes.
Nat.Struct.Mol.Biol., 13, 2006
2BK2
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BU of 2bk2 by Molmil
The prepore structure of pneumolysin, obtained by fitting the alpha carbon trace of perfringolysin O into a cryo-EM map
Descriptor: PERFRINGOLYSIN O
Authors:Tilley, S.J, Orlova, E.V, Gilbert, R.J.C, Andrew, P.W, Saibil, H.R.
Deposit date:2005-02-10
Release date:2005-05-04
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (28 Å)
Cite:Structural Basis of Pore Formation by the Bacterial Toxin Pneumolysin
Cell(Cambridge,Mass.), 121, 2005
4A8B
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BU of 4a8b by Molmil
Symmetrized cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozymes
Descriptor: LYSOZYME C, PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ
Authors:Malet, H, Canellas, F, Sawa, J, Yan, J, Thalassinos, K, Ehrmann, M, Clausen, T, Saibil, H.R.
Deposit date:2011-11-20
Release date:2012-01-11
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (13 Å)
Cite:Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
4AAR
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BU of 4aar by Molmil
ATP-triggered molecular mechanics of the chaperonin GroEL
Descriptor: 60 KDA CHAPERONIN, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Clare, D.K, Vasishtan, D, Stagg, S, Quispe, J, Farr, G.W, Topf, M, Horwich, A.L, Saibil, H.R.
Deposit date:2011-12-05
Release date:2012-12-12
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (8 Å)
Cite:ATP-Triggered Conformational Changes Delineate Substrate-Binding and -Folding Mechanics of the Groel Chaperonin.
Cell(Cambridge,Mass.), 149, 2012
4AAS
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BU of 4aas by Molmil
ATP-triggered molecular mechanics of the chaperonin GroEL
Descriptor: 60 KDA CHAPERONIN, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Clare, D.K, Vasishtan, D, Stagg, S, Quispe, J, Farr, G.W, Topf, M, Horwich, A.L, Saibil, H.R.
Deposit date:2011-12-05
Release date:2012-12-12
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:ATP-Triggered Conformational Changes Delineate Substrate-Binding and -Folding Mechanics of the Groel Chaperonin.
Cell(Cambridge,Mass.), 149, 2012
4AB2
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BU of 4ab2 by Molmil
ATP-triggered molecular mechanics of the chaperonin GroEL
Descriptor: 60 KDA CHAPERONIN, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Clare, D.K, Vasishtan, D, Stagg, S, Quispe, J, Farr, G.W, Topf, M, Horwich, A.L, Saibil, H.R.
Deposit date:2011-12-06
Release date:2012-12-12
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:ATP-Triggered Conformational Changes Delineate Substrate-Binding and -Folding Mechanics of the Groel Chaperonin.
Cell(Cambridge,Mass.), 149, 2012
4D2U
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BU of 4d2u by Molmil
Negative-stain electron microscopy of E. coli ClpB (BAP form bound to ClpP)
Descriptor: CHAPERONE PROTEIN CLPB
Authors:Carroni, M, Kummer, E, Oguchi, Y, Clare, D.K, Wendler, P, Sinning, I, Kopp, J, Mogk, A, Bukau, B, Saibil, H.R.
Deposit date:2014-05-13
Release date:2014-06-04
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Head-to-Tail Interactions of the Coiled-Coil Domains Regulate Clpb Activity and Cooperation with Hsp70 in Protein Disaggregation.
Elife, 3, 2014
4D2Q
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BU of 4d2q by Molmil
Negative-stain electron microscopy of E. coli ClpB mutant E432A (BAP form bound to ClpP)
Descriptor: CLPB
Authors:Carroni, M, Kummer, E, Oguchi, Y, Clare, D.K, Wendler, P, Sinning, I, Kopp, J, Mogk, A, Bukau, B, Saibil, H.R.
Deposit date:2014-05-12
Release date:2014-06-04
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (18 Å)
Cite:Head-to-Tail Interactions of the Coiled-Coil Domains Regulate Clpb Activity and Cooperation with Hsp70 in Protein Disaggregation.
Elife, 3, 2014

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