2H53
| Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26 | Descriptor: | small heat shock protein Hsp26 | Authors: | White, H.E, Orlova, E.V, Chen, S, Wang, L, Ignatiou, A, Gowen, B, Stromer, T, Franzmann, T.M, Haslbeck, M, Buchner, J, Saibil, H.R. | Deposit date: | 2006-05-25 | Release date: | 2006-08-01 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (11.5 Å) | Cite: | Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein hsp26 Structure, 14, 2006
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6QS8
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6QS4
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6QS7
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8B6U
| Mpf2Ba1 monomer | Descriptor: | MAGNESIUM ION, Mpf2Ba1 | Authors: | Marini, G, Poland, B, Leininger, C, Lukoyanova, N, Spielbauer, D, Barry, J, Altier, D, Lum, A, Scolaro, E, Perez-Ortega, C, Yalpani, N, Sandahl, G, Mabry, T, Klever, J, Nowatzki, T, Zhao, J.Z, Sethi, A, Kassa, A, Crane, V, Lu, A, Nelson, M.E, Eswar, N, Topf, M, Saibil, H.R. | Deposit date: | 2022-09-27 | Release date: | 2023-05-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.134 Å) | Cite: | Structural journey of an insecticidal protein against western corn rootworm. Nat Commun, 14, 2023
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8B6W
| Mpf2Ba1 pore | Descriptor: | MAGNESIUM ION, Mpf2Ba1 | Authors: | Marini, G, Poland, B, Leininger, C, Lukoyanova, N, Spielbauer, D, Barry, J, Altier, D, Lum, A, Scolaro, E, Perez Ortega, C, Yalpani, N, Sandahl, G, Mabry, T, Klever, J, Nowatzki, T, Zhao, J.Z, Sethi, A, Kassa, A, Crane, V, Lu, A, Nelson, M.E, Eswar, N, Topf, M, Saibil, H.R. | Deposit date: | 2022-09-27 | Release date: | 2023-05-31 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural journey of an insecticidal protein against western corn rootworm. Nat Commun, 14, 2023
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8B6V
| Mp2Ba1 pre-pore | Descriptor: | MAGNESIUM ION, Mpf2Ba1 | Authors: | Marini, G, Poland, B, Leininger, C, Lukoyanova, N, Spielbauer, D, Barry, J, Altier, D, Lum, A, Scolaro, E, Perez Ortega, C, Yalpani, N, Sandahl, G, Mabry, T, Klever, J, Nowatzki, T, Zhao, J.Z, Sethi, A, Kassa, A, Crane, V, Lu, A, Nelson, M.E, Eswar, N, Topf, M, Saibil, H.R. | Deposit date: | 2022-09-27 | Release date: | 2023-05-31 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural journey of an insecticidal protein against western corn rootworm. Nat Commun, 14, 2023
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8BA7
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8BA8
| CryoEM structure of GroEL-ADP.BeF3-Rubisco. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chaperonin GroEL, ... | Authors: | Gardner, S, Saibil, H.R. | Deposit date: | 2022-10-11 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of substrate progression through the bacterial chaperonin cycle. Proc Natl Acad Sci U S A, 120, 2023
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8BA9
| CryoEM structure of GroEL-GroES-ADP.AlF3-Rubisco. | Descriptor: | 60 kDa chaperonin, ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ... | Authors: | Gardner, S, Saibil, H.R. | Deposit date: | 2022-10-11 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis of substrate progression through the bacterial chaperonin cycle. Proc Natl Acad Sci U S A, 120, 2023
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1GRU
| SOLUTION STRUCTURE OF GROES-ADP7-GROEL-ATP7 COMPLEX BY CRYO-EM | Descriptor: | GROEL, GROES | Authors: | Ranson, N.A, Farr, G.W, Roseman, A.M, Gowen, B, Fenton, W.A, Horwich, A.L, Saibil, H.R. | Deposit date: | 2001-12-16 | Release date: | 2002-01-28 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (12.5 Å) | Cite: | ATP-Bound States of Groel Captured by Cryo-Electron Microscopy. Cell(Cambridge,Mass.), 107, 2001
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1GR5
| Solution Structure of apo GroEL by Cryo-Electron microscopy | Descriptor: | 60 KDA CHAPERONIN | Authors: | Ranson, N.A, Farr, G.W, Roseman, A.M, Gowen, B, Fenton, W.A, Horwich, A.L, Saibil, H.R. | Deposit date: | 2001-12-14 | Release date: | 2002-01-28 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7.9 Å) | Cite: | ATP-Bound States of Groel Captured by Cryo-Electron Microscopy. Cell(Cambridge,Mass.), 107, 2001
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2BK1
| The pore structure of pneumolysin, obtained by fitting the alpha carbon trace of perfringolysin O into a cryo-EM map | Descriptor: | PERFRINGOLYSIN O | Authors: | Tilley, S.J, Orlova, E.V, Gilbert, R.J.C, Andrew, P.W, Saibil, H.R. | Deposit date: | 2005-02-10 | Release date: | 2005-05-04 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (29 Å) | Cite: | Structural Basis of Pore Formation by the Bacterial Toxin Pneumolysin Cell(Cambridge,Mass.), 121, 2005
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2BYU
| Negative stain EM reconstruction of M.tuberculosis Acr1(Hsp 16.3) fitted with wheat sHSP dimer | Descriptor: | HEAT SHOCK PROTEIN 16.9B | Authors: | Kennaway, C.K, Benesch, J.L.P, Gohlke, U, Wang, L, Robinson, C.V, Orlova, E.V, Saibil, H.R, Keep, N.H. | Deposit date: | 2005-08-05 | Release date: | 2005-08-22 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (16.5 Å) | Cite: | Dodecameric Structure of the Small Heat Shock Protein Acr1 from Mycobacterium Tuberculosis. J.Biol.Chem., 280, 2005
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2CGT
| GROEL-ADP-gp31 COMPLEX | Descriptor: | 60 KDA GROEL, CAPSID ASSEMBLY PROTEIN GP31 | Authors: | Clare, D.K, Bakkes, P.J, van Heerikhuizen, H, van der Vies, S.M, Saibil, H.R. | Deposit date: | 2006-03-09 | Release date: | 2006-03-29 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.2 Å) | Cite: | An Expanded Protein Folding Cage in the Groel-Gp31 Complex. J.Mol.Biol., 358, 2006
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2C7E
| REVISED ATOMIC STRUCTURE FITTING INTO A GROEL(D398A)-ATP7 CRYO-EM MAP (EMD 1047) | Descriptor: | 60 KDA CHAPERONIN, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Ranson, N.A, Farr, G.W, Roseman, A.M, Gowen, B, Fenton, W.A, Horwich, A.L, Saibil, H.R. | Deposit date: | 2005-11-22 | Release date: | 2006-02-16 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (14.9 Å) | Cite: | ATP-Bound States of Groel Captured by Cryo-Electron Microscopy Cell(Cambridge,Mass.), 107, 2001
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2C7D
| Fitted coordinates for GroEL-ADP7-GroES Cryo-EM complex (EMD-1181) | Descriptor: | 10 KDA CHAPERONIN MOLECULE: GROES, PROTEIN CPN10, GROES PROTEIN, ... | Authors: | Ranson, N.A, Clare, D.K, Farr, G.W, Houldershaw, D, Horwich, A.L, Saibil, H.R. | Deposit date: | 2005-11-22 | Release date: | 2006-01-25 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.7 Å) | Cite: | Allosteric Signalling of ATP Hydrolysis in Groel-Groes Complexes. Nat.Struct.Mol.Biol., 13, 2006
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2C7C
| FITTED COORDINATES FOR GROEL-ATP7-GROES CRYO-EM COMPLEX (EMD-1180) | Descriptor: | 10 KDA CHAPERONIN MOLECULE: GROES, PROTEIN CPN10, GROES PROTEIN, ... | Authors: | Ranson, N.A, Clare, D.K, Farr, G.W, Houldershaw, D, Horwich, A.L, Saibil, H.R. | Deposit date: | 2005-11-22 | Release date: | 2006-01-25 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | Allosteric Signalling of ATP Hydrolysis in Groel-Groes Complexes. Nat.Struct.Mol.Biol., 13, 2006
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2BK2
| The prepore structure of pneumolysin, obtained by fitting the alpha carbon trace of perfringolysin O into a cryo-EM map | Descriptor: | PERFRINGOLYSIN O | Authors: | Tilley, S.J, Orlova, E.V, Gilbert, R.J.C, Andrew, P.W, Saibil, H.R. | Deposit date: | 2005-02-10 | Release date: | 2005-05-04 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (28 Å) | Cite: | Structural Basis of Pore Formation by the Bacterial Toxin Pneumolysin Cell(Cambridge,Mass.), 121, 2005
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4A8B
| Symmetrized cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozymes | Descriptor: | LYSOZYME C, PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ | Authors: | Malet, H, Canellas, F, Sawa, J, Yan, J, Thalassinos, K, Ehrmann, M, Clausen, T, Saibil, H.R. | Deposit date: | 2011-11-20 | Release date: | 2012-01-11 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (13 Å) | Cite: | Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq Nat.Struct.Mol.Biol., 19, 2012
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4AAR
| ATP-triggered molecular mechanics of the chaperonin GroEL | Descriptor: | 60 KDA CHAPERONIN, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Clare, D.K, Vasishtan, D, Stagg, S, Quispe, J, Farr, G.W, Topf, M, Horwich, A.L, Saibil, H.R. | Deposit date: | 2011-12-05 | Release date: | 2012-12-12 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | ATP-Triggered Conformational Changes Delineate Substrate-Binding and -Folding Mechanics of the Groel Chaperonin. Cell(Cambridge,Mass.), 149, 2012
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4AAS
| ATP-triggered molecular mechanics of the chaperonin GroEL | Descriptor: | 60 KDA CHAPERONIN, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Clare, D.K, Vasishtan, D, Stagg, S, Quispe, J, Farr, G.W, Topf, M, Horwich, A.L, Saibil, H.R. | Deposit date: | 2011-12-05 | Release date: | 2012-12-12 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.5 Å) | Cite: | ATP-Triggered Conformational Changes Delineate Substrate-Binding and -Folding Mechanics of the Groel Chaperonin. Cell(Cambridge,Mass.), 149, 2012
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4AB2
| ATP-triggered molecular mechanics of the chaperonin GroEL | Descriptor: | 60 KDA CHAPERONIN, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Clare, D.K, Vasishtan, D, Stagg, S, Quispe, J, Farr, G.W, Topf, M, Horwich, A.L, Saibil, H.R. | Deposit date: | 2011-12-06 | Release date: | 2012-12-12 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.5 Å) | Cite: | ATP-Triggered Conformational Changes Delineate Substrate-Binding and -Folding Mechanics of the Groel Chaperonin. Cell(Cambridge,Mass.), 149, 2012
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4D2U
| Negative-stain electron microscopy of E. coli ClpB (BAP form bound to ClpP) | Descriptor: | CHAPERONE PROTEIN CLPB | Authors: | Carroni, M, Kummer, E, Oguchi, Y, Clare, D.K, Wendler, P, Sinning, I, Kopp, J, Mogk, A, Bukau, B, Saibil, H.R. | Deposit date: | 2014-05-13 | Release date: | 2014-06-04 | Last modified: | 2017-08-23 | Method: | ELECTRON MICROSCOPY (17 Å) | Cite: | Head-to-Tail Interactions of the Coiled-Coil Domains Regulate Clpb Activity and Cooperation with Hsp70 in Protein Disaggregation. Elife, 3, 2014
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4D2Q
| Negative-stain electron microscopy of E. coli ClpB mutant E432A (BAP form bound to ClpP) | Descriptor: | CLPB | Authors: | Carroni, M, Kummer, E, Oguchi, Y, Clare, D.K, Wendler, P, Sinning, I, Kopp, J, Mogk, A, Bukau, B, Saibil, H.R. | Deposit date: | 2014-05-12 | Release date: | 2014-06-04 | Last modified: | 2017-08-23 | Method: | ELECTRON MICROSCOPY (18 Å) | Cite: | Head-to-Tail Interactions of the Coiled-Coil Domains Regulate Clpb Activity and Cooperation with Hsp70 in Protein Disaggregation. Elife, 3, 2014
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