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5KLA
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BU of 5kla by Molmil
Crystal structure of the drosophila Pumilio RNA-binding domain in complex with hunchback RNA
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Maternal protein pumilio, ...
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2016-06-23
Release date:2016-08-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio.
Elife, 5, 2016
5BYM
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BU of 5bym by Molmil
Crystal structure of the RNA-binding domain of yeast Puf5p bound to SMX2 RNA
Descriptor: RNA (5'-R(*UP*GP*UP*AP*CP*UP*AP*UP*A)-3'), Suppressor protein MPT5
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2015-06-10
Release date:2015-09-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.708 Å)
Cite:RNA regulatory networks diversified through curvature of the PUF protein scaffold.
Nat Commun, 6, 2015
5BZU
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BU of 5bzu by Molmil
Crystal structure of the RNA-binding domain of yeast Puf5p bound to AAT2 RNA
Descriptor: Suppressor protein MPT5, UGUAAUA
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2015-06-11
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:RNA regulatory networks diversified through curvature of the PUF protein scaffold.
Nat Commun, 6, 2015
5BZ1
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BU of 5bz1 by Molmil
Crystal structure of the RNA-binding domain of yeast Puf5p bound to MFA2 RNA
Descriptor: RNA (5'-R(*UP*GP*UP*AP*UP*UP*UP*GP*UP*A)-3'), Suppressor protein MPT5
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2015-06-11
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:RNA regulatory networks diversified through curvature of the PUF protein scaffold.
Nat Commun, 6, 2015
5BZ5
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BU of 5bz5 by Molmil
Crystal structure of the RNA-binding domain of yeast Puf5p bound to AMN1 RNA
Descriptor: RNA (5'-R(*UP*GP*UP*AP*AP*CP*UP*UP*UP*A)-3'), Suppressor protein MPT5
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2015-06-11
Release date:2015-09-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:RNA regulatory networks diversified through curvature of the PUF protein scaffold.
Nat Commun, 6, 2015
5BZV
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BU of 5bzv by Molmil
Crystal structure of the RNA-binding domain of yeast Puf5p bound to SMX2 RNA
Descriptor: RNA (5'-R(*UP*GP*UP*AP*CP*UP*AP*UP*A)-3'), Suppressor protein MPT5
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2015-06-11
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.354 Å)
Cite:RNA regulatory networks diversified through curvature of the PUF protein scaffold.
Nat Commun, 6, 2015
4DZS
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BU of 4dzs by Molmil
Crystal structure of yeast Puf4p RNA binding domain in complex with HO-4BE mutant RNA
Descriptor: 5'-R(*UP*GP*UP*AP*UP*CP*AP*UP*A)-3', Pumilio homology domain family member 4
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2012-03-01
Release date:2012-04-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Patterns and plasticity in RNA-protein interactions enable recruitment of multiple proteins through a single site.
Proc.Natl.Acad.Sci.USA, 109, 2012
6NOF
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BU of 6nof by Molmil
Crystal structure of FBF-2 repeat 5 mutant (C363A, R364Y, Q367S) in complex with 8-nt RNA
Descriptor: 1,2-ETHANEDIOL, Fem-3 mRNA-binding factor 2, RNA (5'-R(*UP*GP*UP*AP*AP*AP*UP*A)-3')
Authors:McCann, K.L, Wang, Y, Qiu, C, Hall, T.M.T.
Deposit date:2019-01-16
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.251 Å)
Cite:Engineering a conserved RNA regulatory protein repurposes its biological function in vivo .
Elife, 8, 2019
3V74
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BU of 3v74 by Molmil
crystal structure of FBF-2 in complex with gld-1 FBEa13 RNA
Descriptor: Fem-3 mRNA-binding factor 2, RNA (5'-R(*UP*CP*AP*UP*GP*UP*GP*CP*CP*AP*UP*AP*C)-3')
Authors:Wang, Y, Qiu, C, Kershner, A, Holley, C.P, Wilinski, D, Keles, S, Kimble, J, Wickens, M, Hall, T.M.T.
Deposit date:2011-12-20
Release date:2012-01-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Divergence of PUF protein specificity through variations in an RNA-binding pocket
J.Biol.Chem., 2012
5SVD
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BU of 5svd by Molmil
Nop9, a new PUF-like protein, prevents premature pre-rRNA cleavage to correctly process mature 18S rRNA
Descriptor: Nucleolar protein 9
Authors:Zhang, J, Qiu, C, Hall, T.
Deposit date:2016-08-05
Release date:2016-10-26
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA.
Nat Commun, 7, 2016
6WPI
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BU of 6wpi by Molmil
Crystal structure of Nop9 in complex with ITS1 RNA
Descriptor: 3,3',3''-phosphanetriyltripropanoic acid, GLYCEROL, Nucleolar protein 9, ...
Authors:Zhang, J, Qiu, C, Hall, T.M.T.
Deposit date:2020-04-27
Release date:2020-05-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Nop9 recognizes structured and single-stranded RNA elements of preribosomal RNA.
Rna, 26, 2020
3REF
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BU of 3ref by Molmil
Crystal structure of EhRho1 bound to GDP and Magnesium
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho-like small GTPase, ...
Authors:Bosch, D.E, Qiu, C, Siderovski, D.P.
Deposit date:2011-04-04
Release date:2011-09-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Unique structural and nucleotide exchange features of the Rho1 GTPase of Entamoeba histolytica.
J.Biol.Chem., 286, 2011
3REG
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BU of 3reg by Molmil
Crystal structure of EhRho1 bound to a GTP analog and Magnesium
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Rho-like small GTPase
Authors:Bosch, D.E, Qiu, C, Siderovski, D.P.
Deposit date:2011-04-04
Release date:2011-09-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Unique structural and nucleotide exchange features of the Rho1 GTPase of Entamoeba histolytica.
J.Biol.Chem., 286, 2011
3QGB
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BU of 3qgb by Molmil
Crystal structure of FBF-2 R288Y mutant in complex with gld-1 FBEa
Descriptor: 5'-R(*UP*GP*UP*GP*CP*CP*AP*UP*A)-3', Fem-3 mRNA-binding factor 2
Authors:Wang, Y, Qiu, C, Koh, Y.Y, Opperman, L, Gross, L, Hall, T.M.T, Wickens, M.
Deposit date:2011-01-24
Release date:2011-03-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Stacking interactions in PUF-RNA complexes.
Rna, 17, 2011
1NGN
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BU of 1ngn by Molmil
Mismatch repair in methylated DNA. Structure of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4
Descriptor: methyl-CpG binding protein MBD4
Authors:Wu, P, Qiu, C, Sohail, A, Zhang, X, Bhagwat, A.S, Cheng, X.
Deposit date:2002-12-17
Release date:2003-03-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mismatch repair in methylated DNA. Structure and activity of the mismatch-specific thymine glycosylase domain of methyl-CpG-binding protein MBD4
J.Biol.Chem., 278, 2003
6NOD
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BU of 6nod by Molmil
Crystal structure of C. elegans PUF-8 in complex with RNA
Descriptor: PUF (Pumilio/FBF) domain-containing, RNA (5'-R(P*UP*GP*UP*AP*UP*AP*UP*A)-3')
Authors:Wang, Y, McCann, K.L, Qiu, C, Hall, T.M.T.
Deposit date:2019-01-16
Release date:2019-01-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.547 Å)
Cite:Engineering a conserved RNA regulatory protein repurposes its biological function in vivo .
Elife, 8, 2019
2ACL
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BU of 2acl by Molmil
Liver X-Receptor alpha Ligand Binding Domain with SB313987
Descriptor: 1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE, Oxysterols receptor LXR-alpha, RETINOIC ACID, ...
Authors:Jaye, M.C, Krawiec, J.A, Campobasso, N, Smallwood, A, Qiu, C, Lu, Q, Kerrigan, J.J.
Deposit date:2005-07-19
Release date:2005-09-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery of substituted maleimides as liver x receptor agonists and determination of a ligand-bound crystal structure.
J.Med.Chem., 48, 2005
6NOC
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BU of 6noc by Molmil
Crystal structure of FBF-2 repeat 5 mutant (C363A, R364Y) in complex with 8-nt RNA
Descriptor: Fem-3 mRNA-binding factor 2, RNA (5'-R(*UP*GP*UP*AP*AP*AP*UP*A)-3')
Authors:McCann, K, Wang, Y, Qiu, C, Hall, T.M.T.
Deposit date:2019-01-16
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.849 Å)
Cite:Engineering a conserved RNA regulatory protein repurposes its biological function in vivo .
Elife, 8, 2019
6NOH
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BU of 6noh by Molmil
Crystal structure of FBF-2 repeat 5 mutant (C363S, R364Y, Q367S) in complex with 8-nt RNA
Descriptor: 1,2-ETHANEDIOL, Fem-3 mRNA-binding factor 2, RNA (5'-R(*UP*GP*UP*AP*AP*AP*UP*A)-3')
Authors:McCann, K.L, Wang, Y, Qiu, C, Hall, T.M.T.
Deposit date:2019-01-16
Release date:2019-01-30
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.249 Å)
Cite:Engineering a conserved RNA regulatory protein repurposes its biological function in vivo .
Elife, 8, 2019
3QG9
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BU of 3qg9 by Molmil
crystal structure of FBF-2/gld-1 FBEa A7U mutant complex
Descriptor: 1,2-ETHANEDIOL, 5'-R(*UP*GP*UP*GP*CP*CP*UP*UP*A)-3', Fem-3 mRNA-binding factor 2
Authors:Koh, Y.Y, Wang, Y, Qiu, C, Opperman, L, Gross, L, Hall, T.M.T, Wickens, M.
Deposit date:2011-01-24
Release date:2011-03-23
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Stacking interactions in PUF-RNA complexes.
Rna, 17, 2011
3QGC
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BU of 3qgc by Molmil
Crystal structure of FBF-2 R288Y mutant in complex with gld-1 FBEa A7U mutant
Descriptor: 5'-R(*UP*GP*UP*GP*CP*CP*UP*UP*A)-3', Fem-3 mRNA-binding factor 2
Authors:Wang, Y, Qiu, C, Koh, Y.Y, Opperman, L, Gross, L, Hall, T.M.T, Wickens, M.
Deposit date:2011-01-24
Release date:2011-03-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Stacking interactions in PUF-RNA complexes.
Rna, 17, 2011
6NHW
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BU of 6nhw by Molmil
Structure of the transmembrane domain of the Death Receptor 5 - Dimer of Trimer
Descriptor: Tumor necrosis factor receptor superfamily member 10B
Authors:Chou, J.J, Pan, L, Fu, Q, Zhao, L, Chen, W, Piai, A, Fu, T, Wu, H.
Deposit date:2018-12-24
Release date:2019-02-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling.
Cell, 176, 2019
6NHY
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BU of 6nhy by Molmil
Structure of the transmembrane domain of the Death Receptor 5 mutant (G217Y) - Trimer Only
Descriptor: Tumor necrosis factor receptor superfamily member 10B
Authors:Chou, J.J, Pan, L, Zhao, L, Chen, W, Piai, A, Fu, T, Wu, H, Liu, Z.
Deposit date:2018-12-24
Release date:2019-02-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling.
Cell, 176, 2019
5V4U
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BU of 5v4u by Molmil
Solution structure of VKK38 bound to plasminogen kringle 2
Descriptor: M protein
Authors:Yuan, Y, Castellino, F.
Deposit date:2017-03-10
Release date:2017-07-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Conformationally organized lysine isosteres in Streptococcus pyogenes M protein mediate direct high-affinity binding to human plasminogen.
J. Biol. Chem., 292, 2017
2YJY
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BU of 2yjy by Molmil
A specific and modular binding code for cytosine recognition in PUF domains
Descriptor: 5'-R(*AP*UP*UP*GP*CP*AP*UP*AP*UP*AP)-3', PUMILIO HOMOLOG 1
Authors:Dong, S, Wang, Y, Cassidy-Amstutz, C, Lu, G, Qiu, C, Bigler, R, Jezyk, M, Li, C, Hall, T.M.T, Wang, Z.
Deposit date:2011-05-24
Release date:2011-06-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:Specific and Modular Binding Code for Cytosine Recognition in Pumilio/Fbf (Puf) RNA-Binding Domains.
J.Biol.Chem., 286, 2011

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